Surgical Management of Hyperlipidemia
At the present time, there are three clinical surgical procedures that have been demonstrated to lower the circulating lipids: jejunoileal by-pass for management of morbid obesity, end-to-side portacaval shunt, and partial ileal by-pass. The primary purpose of jejunoileal by-pass is to achieve a caloric absorptive defect and subsequent weight reduction; an accompanying effect is plasma cholesterol and triglyceride lowering. Systemic diversion of the portal blood stream, long employed in the treatment of portal hypertension and esophageal varices, has been suggested as a therapeutic approach in the treatment of type IIa homozygous hyperlipoproteinemia in children. The partial ileal by-pass was designed specifically as a means to achieve cholesterol lowering.
KeywordsEsophageal Varix Cholesterol Lowering Glycogen Storage Disease Cholesterol Reduction Portacaval Shunt
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