Abstract
At the present time, there are three clinical surgical procedures that have been demonstrated to lower the circulating lipids: jejunoileal by-pass for management of morbid obesity, end-to-side portacaval shunt, and partial ileal by-pass. The primary purpose of jejunoileal by-pass is to achieve a caloric absorptive defect and subsequent weight reduction; an accompanying effect is plasma cholesterol and triglyceride lowering. Systemic diversion of the portal blood stream, long employed in the treatment of portal hypertension and esophageal varices, has been suggested as a therapeutic approach in the treatment of type IIa homozygous hyperlipoproteinemia in children. The partial ileal by-pass was designed specifically as a means to achieve cholesterol lowering.
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Supported by National Heart and Lung Institute Grants HL 11901 and HL 15265 and a Special Legislative Appropriation of the State of Minnesota. Direct reprint requests to Dr. Henry Buchwald, Box 290, University of Minnesota Hospitals, Minneapolis, Minnesota 55455.
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© 1977 Springer-Verlag Berlin Heidelberg
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Buchwald, H., Guzman, I.J., Moore, R.B., Varco, R.L. (1977). Surgical Management of Hyperlipidemia. In: Schettler, G., Goto, Y., Hata, Y., Klose, G. (eds) Atherosclerosis IV. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95308-8_99
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DOI: https://doi.org/10.1007/978-3-642-95308-8_99
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