In recent years, several studies have shown that diet-induced proliferative uncomplicated atherosclerotic lesions regress after removal of the dietary stimulus Such regression has been reported in monkeys (Armstrong et al., 1970; Tucker et al., 1971; Vesselinovitch et al., 1973), chickens (Pick et al., 1952; Horlick and Katz, 1949), pigeons (Clarkson et al., 1971; St. Clair et al., 1972), and dogs (Bevans et al., 1951; De Palma et al., 1970). In rabbits, however, regression of artherosclerotic lesions appears to occur only when lesions are produced by cholesterol feeding for a short period (Bortz, 1968). No appreciable regression of artherosclerotic lesions has been reported in rabbits when cholesterol was fed for a long period (Friedman and Byers, 1963; Prior and Ziegler, 1965). In many instances, withdrawal of the dietary stimulus was followed by further progression of the disease (Constantinides, 1965).
KeywordsCholesterol Catheter Estrogen Foam Corticosteroid
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