Structure of the Renal Artery and its Vasoconstriction
The structure of the renal arteries within the kidney is characterized by well-developed smooth muscle in the media. The smooth muscle cells are connected with each other by intercalating pattern; protrusion of cytoplasma of one smooth muscle cell invaginating into the cytoplasma of neighboring cells (Burnstock, 1970; Somlyo and Somlyo, 1968). With the aid of high magnification of the electron microscope, there are seen a considerable number of nexus where two cytomembranes are merged inperseptively. The fluorescent method according to Falck (1962) reveals that monoamines involving noradrenaline and adrenaline are located at the outer most layer of medial smooth muscle cells. No site of monoamine deposition within the media is discernible. This indicates that sympathetic innervation terminates subjacent to the adventitia. And the stimulus leading to vasoconstriction is conducted by action potential running on the surface of cytomembrane of the medial cells from the outer most cell to the inner most one, when the sympathetic nerve is excited.
KeywordsRenal Artery Chondroitin Sulfate Sympathetic Innervation Study Risk Factor Sclerotic Change
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