Adriamycin in the Treatment of Acute Leukemia

  • J. M. A. Whitehouse
  • D. Crowther
  • J. S. Malpas
Conference paper


The report by Bonadonna and his colleagues in 1969 of the effectiveness of the anti-tumor antiobiotic adriamycin in a variety of malignant conditions including those affecting children suggested that a trial in acute leukemia should be undertaken. A total of 29 patients have so far been treated who have been in relapse with either acute lymphoblastic leukemia, acute myelogenous leukemia or lymphoblastic lymphosarcoma. 10 patients had acute lymphoblastic leukemia, 13 acute myelogenous leukemia and 6 had lymphoblastic lymphosarcoma (Table 1).


Complete Remission Acute Lymphoblastic Leukemia Acute Leukemia Partial Remission Acute Myelogenous Leukemia 
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  1. 1.
    Bonadonna, G., Monfardini, S., Delina, M., Fossati-Bellani, F.: Brit. med. J. 1969III, 503.Google Scholar
  2. 2.
    Hardisty, R. M., Mcelwain, T. J., Darby, C. W.: Brit. med. J. 1969II, 662.Google Scholar
  3. 3.
    Crowther, D., Bateman, C. J. T., Vartan, C. P., Whitehouse, J. M. A., Malpas, J. S., Hamilton Fairley, G., Scott, R.B.: Brit. med. J. 1970IV, 513.Google Scholar
  4. 4.
    Malpas, J. S., Scott, R. B.: Brit. med. J. 1968III, 227.Google Scholar
  5. 5.
    Malpas, J. S., Scott, R. B.: Lancet 19691, 469.Google Scholar
  6. 6.
    Mathe, G., Amiel, J. L., Hayat, M., Devassal, F., Schwartzenberg, L., Schneider, M., Jasmin, C., Rosenfeld, C.: Presse méd. 78, 1997 (1970).PubMedGoogle Scholar

Copyright information

© Springer-Verlag, Berlin Heidelberg 1972

Authors and Affiliations

  • J. M. A. Whitehouse
    • 1
  • D. Crowther
    • 1
  • J. S. Malpas
    • 1
  1. 1.Department of Medical OncologySt. Bartholomew’s HospitalLondon E.C.L./Great BritainUSA

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