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New Ideas and Data on Competence and DNA Entry in Transformation of Bacillus subtilis

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Current Topics in Microbiology and Immunology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 53))

Abstract

The steps involved in bacterial transformation can be divided into two main categories, those leading to the juxtapositioning (synapsis) of the donor and recipient genes and those involved in the subsequent recombinational processes. The elucidation of the mechanism by which the latter step is accomplished is of general importance to the field of genetics since similar mechanisms could quite possibly be responsible for genetic exchange reactions in all living systems. On the other hand, one might consider studies concerned with the juxaposition reactions of a more limited value in view of the uniqueness of bacterial transformation as regards the ability of purified DNA to transfer information and thus to induce hertiable genetic alterations. But, to the contrary, the understanding of the basic mechanisms involved in the process of DNA transport in bacterial transformation might be of great importance since it may provide insights into the manner in which the surfaces of more complex cells can interact with and respond to informational macromolecules in the environment.

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  1. Division of Biological and Medical Research, Argonne National Laboratory, Argonne, Illinois, USA

    Robert J. Erickson

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  1. Genéve, Switzerland

    W. Arber

  2. New Brunswick, USA

    W. Braun

  3. Göttingen, Germany

    F. Cramer

  4. Freiburg, Germany

    R. Haas

  5. Philadelphia, USA

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  14. Würzburg, Germany

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Erickson, R.J. (1970). New Ideas and Data on Competence and DNA Entry in Transformation of Bacillus subtilis. In: Arber, W., et al. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology, vol 53. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95180-0_3

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