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Isolierung einer löslichen Östriol-Glucuronyltransferase aus der Leber des Menschen

Isolation of a Soluble Estriol-Glucuronyl-Transferase from Human Liver

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Oestrogene Hypophysentumoren

Part of the book series: Oestrogene Hypophysentumoren ((ENDOKRINOLOGIE,volume 15))

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Summary

The isolation and partial purification of a soluble estriol-16α-glueuronyltransferase from human liver is described. The partially purified enzyme appears to be very unstable. Kinetic studies revealed a pH optimum of 8.0 in Tris-HCl buffer, a K m of 0.96 × 10-5 M for estriol and K m of 1.43 × 10-5 M for UDP-glueuronic acid. Estrone, estradiol and testosterone are not conjugated by the enzyme.

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Literatur

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Author information

Authors and Affiliations

  1. Institut für Klinische Biochemie, Universität Bonn, Deutschland

    G. S. Rao & H. Breuer

Authors
  1. G. S. Rao
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  2. H. Breuer
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Editor information

Editors and Affiliations

  1. Pathologisches Institut der Universität, 6300, Gießen, Klinikstraße 32g, Deutschland

    Joachim Kracht

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© 1969 Springer-Verlag Berlin · Heidelberg

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Rao, G.S., Breuer, H. (1969). Isolierung einer löslichen Östriol-Glucuronyltransferase aus der Leber des Menschen. In: Kracht, J. (eds) Oestrogene Hypophysentumoren. Oestrogene Hypophysentumoren, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95126-8_33

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  • DOI: https://doi.org/10.1007/978-3-642-95126-8_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-95127-5

  • Online ISBN: 978-3-642-95126-8

  • eBook Packages: Springer Book Archive

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