Summary
The myometrium cell of the rabbit contains a 17β-hydroxysteroid: NAD(P) oxidoreductase, which can be induced by the physiological amount of 1 μg estradiol-17β/kg bw. The peak of the increase of activity, caused by 17ß/-estradiol, is reached within 40 h after administration of hormone. Possibly the duration of estrogen action on this target organ may be regulated by the cytoplasmatic 17β/-hydroxysteroid: NAD(P)-oxidoreduetase, which is reacting with estradiol-17β/ as substrate.
Die Untersuchungen wurden mit Unterstützung der Deutschen Forschungsgemeinschaft durchgeführt.
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© 1969 Springer-Verlag Berlin · Heidelberg
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Jütting, G. (1969). Oestradiolabhängige Induktion einer 17β-Hydroxysteroid-Oxydoreduktase im Myometrium von Kaninchen als ein möglicher Weg zur Kontrolle der Oestrogenwirkung auf ein Erfolgsorgan. In: Kracht, J. (eds) Oestrogene Hypophysentumoren. Oestrogene Hypophysentumoren, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95126-8_30
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DOI: https://doi.org/10.1007/978-3-642-95126-8_30
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