Summary
Oestrone sulfate and Equilin sulfate, main components of the pregnant mare urines conjugated oestrogens, are oral highly active in different biological tests. In contrast Equilenin, its sulfate and 17α-Oestradiol are weak compounds. In the human the oral dose for the proliferation of an atrophic endometrium is 30 mg for Oestrone sulfate, 30 mg for Equilin sulfate. 17α-Oestradiol was ineffective in doses up to 70 mg. The effect on vaginal smear, cervical mucus and gonadotropin excretion corresponded to the oestrogenic activity.
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© 1969 Springer-Verlag Berlin · Heidelberg
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Lauritzen, C. (1969). Oestrogenaktivität von 17α-Oestradiol, Equilin, Equilenin und ihren Sulfokonjugaten im Tierversuch und beim Menschen. In: Kracht, J. (eds) Oestrogene Hypophysentumoren. Oestrogene Hypophysentumoren, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95126-8_17
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DOI: https://doi.org/10.1007/978-3-642-95126-8_17
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