Zusammenfassung
Angeborene Störungen der spezifischen Infektabwehr sind seltene Erkrankungen. Aus folgenden Gründen kommt ihnen grundsätzliches Interesse zu: ihr ausführliches Studium erlaubt wesentliche Aussagen über physiologische Abwehr- und Entzündungsvorgänge; ferner vermitteln sie uns einen Einblick in die Ontogenese immunbiologischer Mechanismen, und schließlich sind manche Störungen hereditär fixiert, so daß die Krankheiten auch vom genetischen Standpunkt aus besonderes Interesse beanspruchen. Humanmedizinische Erfahrungen und tierexperimentelle Befunde haben zu interessanten neuen pathophysiologischen Vorstellungen und Arbeitshypothesen geführt, die heute zum Teil allgemein anerkannt sind, zum Teil noch lebhaft diskutiert werden (s. S. 133).
Arbeit mit Unterstützung des Schweizerisehen Nationalfonds zur Förderung der wissenschaftlichen Forschung.
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Literatur
Ackerman, G. A., and R. A. Knouff: Lymphocytopoiesis in the bursa of Fabricius. Amer. J. Anat. 104, 163 (1959).
Aiuti, F., S. Ungari, G. Turbessi, and G. B. Serra: Immunologic aspects of congenital syphilis. Helv. paediat. Acta 21, 66 (1966).
Aldrich, R. A., A. G. Steinberg, and D. C. Campbell: Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea. Pediatrics 13, 133 (1954).
Allibone, E. O., W. Goldie, and B. P. Marmion: Pneumocystis Carinii pneumonia and progressive vaccinia in siblings. Arch. Dis. Childh. 39, 26 (1964).
Amlie, R.: Moniliase. („Essentielle Lymphocytophthise“ Glanzmann et Riniker). Ann. paediat. (Basel) 179, 316 (1952).
Ammann, P., V. Lopez, R. Buetler u. E. Rossi: Das Ataxie-Teleangiektasie-Syndrom (Louis-Bar-Syndrom) aus immunologischer Sicht. Helv. paediat. Acta 20, 137 (1965).
Ariztia, A., L. Moreno, C. Garces y R. Montero: Caso fatal de generalizacion de B.C.G. Rev. chil. Pediat. 31, 70 (1960).
Astaldi, G., R. Airó, G. Costa u. N. Duarte: Milzbestrahlung und immunologische Antwort peripherer Lymphozyten von chronisch-lymphatischen Leukämien. Blut 13, 100 (1966).
Auerbach, R.: Morphogenetic interactions in the development of the mouse thymus gland. Develop. Biol. 2, 271 (1960).
— Experimental analysis of the origin of cell types in the development of the mouse thymus. Develop. Biol. 3, 336 (1961).
— Experimental analysis of the mouse thymus and spleen morphogenesis. In: The thymus in immunobiology, (Good, R. A., and A. E. Gabrielsen, eds.), p.95. New York: Hoeber & Harper 1964.
Azar, H. A., J. Williams, and K. Takatsuki: Development of plasma cells and immunoglobulins in neonatally thymectomized rats. In: The thymus (Defendi, V., and D. Metcale, eds.), p. 75. Philadelphia: Wistar Institute Press 1964.
Bach, F. H.: Cellular studies in agammaglobulinemia. 3. Developmental Immunology Workshop, Sanibel, 1967.
—, and K. Hirschhorn: γ-globulin production by human lymphocytes in vitro. Exp. Cell. Res. 32, 592 (1963).
—— Lymphocyte interaction: A potential histocompatibility test in vitro. Science N.S. 143, 813 (1964).
—, and N. K. Voynow: One-way stimulation in mixed leukocyte cultures. Science 153, 545 (1966).
Backhausz, R., M. Koltay, G. Bátory u. G. Tóth: Paragammaglobulinämie, charakterisiert durch die Bildimg von Gammaglobulin mit defizienter Antigenität, Mangel an Beta-2M-Globulin und ein partielles Antikörpermangelsyndrom. Eolia haemat. (Leipzig) 86, 3 (1966).
Barandun, S.: Die Gammaglobulin-Therapie. Chemische, immunologische und klinische Grundlagen. Bibl. Haematol. Fasc. 17. Basel/New York: Karger 1964.
— H. Buechler u. A. Haessig: Agammaglobulinämie. Helv. med. Acta 22, 456 (1955).
——— Das Antikörpermangelsyndrom (Agammaglobulinämie). Schweiz. med. Wschr. 86, 33 (1956).
— H. Cottier, and A. Haessig: New aspects of agammaglobulinemia and antibody deficiency syndrome. Immunopathology, 1st Internat. Symp., Basel/Seelisberg 1958, ed. by P. Grabar and P. Miescher, p. 60. Basel/Stuttgart: B. Schwabe 1959.
——— u. G. Riva: Das Antikörpermangelsyndrom. Basel: Schwabe 1959.
— H. J. Huser u. A. Haessig: Klinische Erscheinungsformen des Antikörpermangelsyndroms. Schweiz, med. Wschr. 88, 78 (1958).
Barbero, G. J., A. Gray, Th. F. M. Scott, and C. H. Kempe: Vaccinia gangrenosa treated with hyperimmune vaccinal gamma globulin. Pediatrics 16, 609 (1955).
Bealmear, M., and R. Wilson: Homograft rejection by neonatally thymectomized germfree mice. (in press.)
Becker, Hj., Y. Kudo, H. Argentos u. H. Fischer: Cytologische Untersuchungen bei der lokalen Entzündung. Folia haemat. (Frankfurt/Main) N.F. 5, 91 (1961).
Beltaos, E., and S. R. McCreadie: Thymic alymphoplasia with pancreatic fibrosis and mucoviscidosis. J. Lancet (Minneap.) 85, 254 (1965).
Bernard, R., J. Coignet, G. Casamata et E. Gerin: Un nouveau cas de lymphocyto-phtisie avec hypogammaglobulinémIe à manifestations respiratoires prédominantes. Pédiatrie 18, 821 (1963).
Bernheim, M., R. François, F. Larbre, D. Rosenberg, R. Creyssel, Y. Manuel et M.-T. Freycon: Les carences dissociées en anticorps. A propos d’une observation d’infections à répétition par absence de β 2M et β 2A globulines. Pédiatrie 19, 189 (1964).
Bethenod, M., J.-L. Nivelon, J. Gilly et J.-M. Pouillaude: Un nouveau cas d’aplasie lympho-plasmocytaire avec agammaglobulinémie et pneumonie à „Pneumocystis Carinii“. Echec d’une greffe de thymus. Pédiatrie 21, 87 (1966).
Beyer, P., A. Wasmer, M. Peter et M.-L. Malfroy: Acrodermatitis enteropathica. Pédiatrie 21, 677 (1966).
Bigler, J. A., and E. L. Slotkowski: Smallpox vaccination with prolonged vaccinia. Pediatrics 7, 24 (1951).
Blake, J. C.: Case of progressive vaccinia. Brit. med. J. 1958 II, 492.
Blum, A.: Pneumocystis Carinii. Schweiz. med. Wschr. 96, 471 (1966).
Boder, E., and R. P. Sedgwick: Ataxia-telangiectasia. A familial syndrome of progressive cerebellar ataxia, oculocutaneous telangiectasia and frequent pulmonary infection. Pediatrics 21, 526 (1958).
Boggs, D. R., J. W. Athens, O. P. Haab, S. O. Raab, G. E. Cartwight, and M. M. Wintrobe: Induced inflammatory exudates in normal man. A method designed to study the qualitative and quantitative cellular response to a pyogenic stimulus. Amer. J. Path. 44, 61 (1964).
Boniface, L.: Les globulines immunes de l’enfant. Thèse pour le doctorat en médecine. Lille 1962.
Bonnevier, J. O., J. Killander, L. Olding, and B. Vahlquist: Congenital agammaglobulin-aemia in the brother of a boy who died of generalized BCG infection. Acta paediat. (Uppsala) 58, 55 (1964).
Boettiger, E., u. W. Wernstedt: Beitrag zur Kenntnis der spasmophilen Diathese. Acta pediat. 6, 373 (1927).
Bouton, J., D. Mainwaring, and R. W. Smithells: B.C.G. dissemination in congenital hypogammaglobulinemia. Brit. med. J. 1963 I, 1512.
Breton, A., R. Walbaum, L. Boniface, M. Goudemand et A. Dupont: Lymphoeytophtisie avec dysgammaglobulinémie chez un nourrisson. Arch, franç. Pediat. 20, 131 (1963).
Bruton, O. C.: Agammaglobulinemia. Pediatrics 9, 722 (1952).
— L. Apt, D. Gitlin, and Ch. A. Janeway: Absence of serum gamma globulin. Trans. Soc. Ped. Research, 22nd Annual Meeting, Old Point Comfort, Va, May 5–7, 1952. Amer. J. Dis. Child. 84, 632 (1952).
Buetler, R.: Approche méthodologique des syndromes de défibrination. Méd. et Hyg. (Genève) 21, 1108 (1963).
Burke, B. A., L. J. Krovetz, and R. A. Good: Occurrence of Pneumocystis Carinii pneumonia in children with agammaglobulinemia. Pediatrics 28, 196 (1961).
Burtin, P.: Les agammaglobulinémies. Rev. franç. Étud. clin. biol. 111, 62 (1958).
— D. Buffe et P. Grabar: Les hypogammaglobulinémies atypiques. (Hypogammaglobulin-émies récessives non liées au sexe). Etude immunochimique et génétique. Ann.Inst.Pasteur 106, 519 (1964).
Carlgren, L. E., C. G. Hansson, L. Henricsson, and P. Waehlén: Fatal BCG infection in an infant with congenital lymphocytopenic agammaglobulinemia. Acta paediat. (Uppsala) 55, 636 (1966).
Centerwall, W. R., and M. M. Miller: Ataxia, telangiectasia, and sinopulmonary infections. Amer. J. Dis. Child. 95, 385 (1958).
Chang, T. S., B. Glick, and A. R. Winter: The significance of the bursa of Fabricius in chickens in antibody production. Poultry Sci. 34, 1187 (1953).
Clark, S. L.: Cytological evidences of secretion in the thymus. In: Thymus— Experimental and clinical studies. A CIBA Symposium (Wolstenholme, G. E. W., and R. Porter, eds.), p. 3. London: Churchill 1966.
Claverie, P., A. Dalous, J. Benazet, Solomiac et Lacassin: Agammaglobulinémie congénitale— Echec de la thérapeutique. Sem. Hôp. Paris 33, 1121 (1957).
Cocchi, P., e A. Ulivelli: Vaccino generalizzato trattato con 5-iodo-2'-desossiuridina. Riv. Clin, pediat. 73, 1 (1964).
Connolly, J. H., G. W. A. Dick, and C. M. B.Field: A fatal case of progressive vaccinia. Brit. med. J. 19620 I, 1315.
Cooper, M.: Immunologic defects in patients with Wiskott-Aldrich syndrome. 3rd Developmental Immunology Workshop, Sanibel (1967).
Cooper, M. D., P. Chase, J. W. ST. Geme jr., W. Krivit, and R. A. Good: Wiskott-Aldrich syndrome: Model of impaired defense mechanisms. J. Lab. clin. Med. 64, 849 (1964).
— A. E. Gabrielsen, R. D. A. Peterson, and R. A. Good: Ontogenetic development of the germinal centers and their function-relationships to the bursa of Eabricius. In: Germinal centers in immune responses (H. Cottier, N. Odartchenko, R. Schindler, and C. C. Congdon, eds.). Berlin-Heidelberg-New York: Springer 1967.
— R. D. A. Peterson, and R. A. Good.: A new concept of the cellular basis of immunity. J. Pediat. 67, 907 (1965).
——— Ontogenetic development of the germinal centers and their function-relationship to the bursa of Fabricius. In: Germinal Centers in immune responses. (H. Cottier, N. Odartchenko, R. Schindler, and C. C. Congdon, eds.) Berlin-Heidelberg-New York: Springer 1967.
— M. L. Schwartz, and R. A. Good: Restoration of gamma globulin production in agamma-globulinemic chickens. Science 151, 471 (1966).
Cottier, H.: Zur Histopathologie des Antikörpermangelsyndroms. Trans. 6th Congr. Europ. Soc. Haemat. Copenhagen 1957, p. 41. Basel-New York: Karger 1958.
— Zur Histopathologie des Antikörpermangelsyndroms. Schweiz, med. Wschr. 88, 82 (1958).
— Strahlenbedingte Lebensverkürzung. Berlin-Göttingen-Heidelberg: Springer 1961.
— Lymphoreticular dysplasia in idiopathic antibody deficiency syndromes. 16th Scientific Meeting of the Protein Foundation, Cambridge, Mass., 1961. Vox Sang. 7, 119 (1962).
— K. Buerki, M. Hess, and A. HaessiG: Pathological considerations of immunologic deficiency diseases. 3rd Developmental Immunology Workshop, Sanibel (1967).
— N. Odartchenko, G. Keiser, M. Hess, and R. D. Stoner: Incorporation of tritiated nucleosides and amino acids into lymphoid and plasmoeytoid cells during secondary response to tetanus toxoid in mice. Ann. N. Y. Acad. Sci. 113, 612 (1964).
Craig, J. M., D. Gitlin, and T. C. Jewett: The response of lymph nodes of normal and congenitally agammaglobulinemic children to antigenic stimulation. Amer. J. Dis. Child. 88, 626 (1954).
Cruchaud, A., C. Laperrouza, S. Huguenin Dumittan, and P. E. Ferrier: Agammaglobulinemia in one of two identical twins. Amer. J. Med. 40, 127 (1966).
—— and R. Mégevand: Twins with acquired agammaglobulinemia. Therapeutical prospects. 3rd Developmental Immunology Workshop, Sanibel (1967).
— F. S. Rosen, J. M. Craig, Ch. A. Janeway, and D. Gitlin: The site of synthesis of the 19 S γ-globulins in dysgammaglobulinemia. J. exp. Med. 115, 1141 (1962).
Daamen, C. B. F., M. S. M. Daniels-Bosman, J. Engelhardt en J. Huisman: Een zuigling met vaccinia generalisata. Ned. T. Geneesk. 107, 909 (1963).
Daly, J. J., and E. Jackson: Vaccinia gangrenosa treated with N-Methylisatin β-Thiosemi-carbazone. Brit. med. J. 1962 II 1300.
Damaël, A.: A propos d’un cas de „lymphopénie du nourrisson“ avec β-2-macro-globulinémie transitoire. Thèse pour le doctorat en médecine, Lille 1962.
Delta, B. G., A. M. Rothenberg, H. D. Ainsworth, and F. Innella: Congenital alympho-plasmacytic agammaglobulinemia with thymic dysplasia. J. Amer. med. Ass. 194, 507 (1965).
Donohoe, W. L.: Alymphocytosis. Pediatrics 11, 129 (1953).
Dooren, L. J.: Persönliche Mitteilung 1966.
Dukor, P., u. J. F. A. P. Miller: Physiologie und Pathologie der Thymusfunktion. Ergebn. inn. Med. Kinderheilkunde (in Vorbereitung).
Dzieniszewska-Klepacka, A. L., et Z. Lewicki: Un cas d’infection généralisée et fatale au BCG chez un enfant de 5 mois 1/2 avec dysfonctionnement hormonal. In: Thèse de Heitz-Bauer, Strasbourg 1959, p. 60 (zit. nach Veslot). Gruźlica 26, 43 (1958).
Elves, M. W. (ed.): The biological effects of phytohaemagglutinin. Proc. of the Symposium, held at The Charles Salt Research Centre, 19–21 September 1966.
— S. Roath, and M. C. G. Israëls: The response of lymphocytes to antigen challenge in vitro. Lancet 1963 I, 806.
—— G. Taylor, and M. C. G. Israëls: The in vitro-production of antibody lymphocytes. Lancet 1963 I, 1292.
Falkmer, St., A. Lind, and L. Ploman: Fatal tuberculosis from BCG vaccination. Acta paediat. (Uppsala) 44, 219 (1955).
Färber, W., and G. F. Vawter: Clinical pathological conference. J. Pediat. 56, 690 (1960).
Fincher Hays, E.: The effects of allografts of thymic epithelial reticular cells on the lymphoid tissues of neonatally thymectomized mice. Blood 29, 29 (1967).
Finstad, J., and R. A. Good: Phylogenetic development of immunity and the lymphoid system. Proc. Xth Congr. Internat. Soc. Haemat. H 17, Stockholm 1964.
Fireman, Ph., M. Boesman, and D. Gitlin: Ataxia telangiectasia. A dysgammaglobulin-aemia with deficient gamma1A (beta2A)-globulin. Lancet 1964 I, 1193.
— H. A. Johnson, and D. Gitlin: Presence of plasma cells and γ1m-globulin synthesis in a patient with thymic alymphoplasia. Pediatrics 37, 485 (1966).
Firkin, B. G., and C. R. B. Blackburn: Congenital and acquired agammaglobulinemia. A report of four cases. Quart. J. Med. 27, 187 (1958).
Flewett, T. H., and F. L. Ker: A case of vaccinia necrosum (or progressive vaccinia), with severe hypogammaglobulinemia, treated with N-Methyl Isatin Beta-Thiosemicarbazone (33T57). J. clin. Path. 16, 271 (1963).
Ford, F. R.: Diseases of the nervous system in infancy, childhood and adolescence. 4th ed., p. 944. Springfield (Ill.): Ch. Thomas 1960.
Freycon, F.: L’aplasie lymphoplasmocytaire du nourrisson avec alymphocytose et hypo-gammaglobulinémie. Diss. med. Lyon 1960, (Editions de l’A.G.E.L. 1960).
— M. Jeune, F. Larbre et D. Germain: La lymphocytophtisie essentielle: Aplasie lymphoplasmocytaire du nourrisson avec alymphocytose et hypogammaglobulinémie. Rev. franç. Étud. clin. biol. 6, 817 (1961).
Frick, P. G., and R. A. Good: Studies on agammaglobulinemia. VI. Hemostasis in patients with agammaglobulinemia. Proc. Soc. exp. Biol. (N. Y.) 91, 169 (1956).
Frick, P. H., u. W. H. Hitzig: Zur Klinik und Pathogenese der thrombotischen Mikroangiopathie. Vorkommen bei Antikörpermangel. Schweiz, med. Wsehr. 89, 58 (1959).
Fridrich, R., and M. Schaefer: The phagocytic activity of Kupffer cells after thymectomy. Experientia (Basel) 22, 676 (1965).
Fudenberg, H. H., J. F. Heremans, and E. C. Franklin: A hypothesis for the genetic control of synthesis of the gamma-globulins. Ann. Inst. Pasteur 104, 155 (1963).
Fulginiti, V. A., W. E. Hathaway, D. S. Pearlman, W. R. Blackburn, C. W. Reiquam, J. H. Githens, H. N. Claman, and C. H. Kempe: Dissociation of delayed-hypersensitivity and antibody synthesizing capacities in the human: Report of two sibships with thymic dysplasia, lymphoid tissue depletion, and normal immunoglobulins. (in press).
— C. H. Kempe, W. E. Hathaway, D. S. Pearlman, O. F. Sieber jr., J. W. Joyner jr., J. J. Eller, and A. Robinson: Disseminated vaccinia virus infection in immunologically-defieient individuals. 3rd Developmental Immunology Workshop, Sanibel (1967).
van Furth, R., H. R. E. Schuit, and W. Hijmans: The immunological development of the human fetus. J. exp. Med. 122, 1173 (1965).
Galloway, W. H., and L. M. MacBean: Generalized vaccinia. Brit. med. J. 1956 II, 1102.
—— Generalized vaccinia in infancy. A report of four cases. Brit. med. J. 1958 II, 490.
Gardborg, O., O. H. Iversen, I. Hesselberg, and J. B. Torheim: Generalized BCG infection with fatal course in an infant. Acta paediat. (Uppsala) 52, 293 (1963).
di George, A. M.: Diskussion zu: A new concept of the cellular basis of immunity (Cooper et al.). J. Pediat. 67, 907 (1965).
— H. W. Lischner, C. Dacou, and J. B. Arey: Congenital absence of the thymus and its immunologic consequences. 3rd Developmental Immunology Workshop, Sanibel (1967).
Gewürz, H., R. Pickering, A. R. Page, A. J. Fish, and R. A. Good: Studies on complement and complement components in human disease. 3rd Developmental Immunology Workshop, Sanibel (1967).
Giedion, A., u. J. J. Scheidegger: Kongenitale Immunparese bei Fehlen spezifischer Beta2-Globuline und quantitativnormalen Gamma-Globulinen. Helv. paediat. Acta 12, 241 (1957).
Gitlin, D.: Low resistance to infection: relationship to abnormalities in gamma globulin. Bull. N. Y. Acad. Med. 31, 359 (1955).
—, and J. M. Craig: The thymus and other lymphoid tissues in congenital agammaglobulinemia. 1. Thymic alymphoplasia and lymphocytic hypoplasia and their relation to infection. Pediatrics 32, 517 (1963).
— P. A. Gross, and Ch. A. Janeway: The gamma globulins and their clinical significance. I. Chemistry, immunology, and metabolism. II. Hypogammaglobulinemia. New Engl. J. Med. 260, 21 u. 72 (1959).
— W. H. Hitzig, and Ch. A. Janeway: Multiple serum protein deficiencies in congenital and acquired agammaglobulinemia. J. clin. Invest. 35, 1199 (1956).
—, and Ch. A. Janeway: Agammaglobulinemia. Congenital, acquired and transient forms. Progr. Hemat. 11, 318 (1956).
— F. S. Rosen, and Ch. A. Janeway: The thymus and other lymphoid tissues in congenital agammaglobulinemia. II. Delayed hypersensitivity and homograft survival in a child with thymic alymphoplasia. Pediatrics 33, 711 (1964).
— G. Vawter, and J. M. Craig: Thymic alymphoplasia and congenital aleukocytosis. Pediatrics 33, 184 (1964).
Glanzmann, E., u. P. Riniker: Essentielle Lymphoeytophthise. Ein neues Krankheitsbild aus der Säuglingspathologie. Ann. paediat. (Basel) 175, 1 (1950).
Glauser, P. G.: Ataxia-Telangiectasia (Syndrom von Louis-Bar). Diss. med. Bern 1964.
Gleich, J., J. J. Condemi, and J. H. Yaughan: Dysgammaglobulinemia in the presence of plasma cells. New Engl. J. Med. 272, 331 (1965).
Glick, B.: Further evidence for the role of the bursa of Fabricius in antibody production. Poultry Sci. 37, 240 (1958).
— T. S. Chang, and R. G. Jaap: The bursa of Fabricius and antibody production. Poultry Sci. 35, 224 (1956).
Goldman, A. S., M. E. Haggard, J. W. McFadden, S. E. Ritzman, E. W. Houston, and R. L. Bratcher: Lymphopenic antibody deficiency syndrome, lymphoproliferative disease and multiple allergies. Hyper-γA, normal γM-, hypo-γG- and A-γD-globulinemia. A possible new congenital disorder. 36 th Ann. Meet. Soc. Ped. Research, Atlantic City, N. J. April 1966.
Goldstein, G., and S. Whittingham: Experimental autoimmune thymitis. An animal model of human myasthenia gravis. Lancet 1966 II, 315.
Good, R. A.: Agammaglobulinemia: an experimental study. Amer. J. Dis. Child. 88, 625 (1954).
— Studies on agammaglobulinemia. II. Failure of plasma cell formation in the bone marrow and lymph nodes of patients with agammaglobulinemia. J. Lab. clin. Med. 46, 167 (1955).
— Agammaglobulinemia. II An experimental study. Amer. J. Dis. Child. 90, 577 (1955).
— Disorders of the immune system. Hosp. Pract. 2, 39 (1967).
— A. E. Gabrielsen, R. D. A. Peterson, J. Finstad, and M. D. Cooper: The development of the central and peripheral lymphoid tissue— ontogenetic and phylogenetie considerations. In: Thymus— Experimental and clinical studies. A CIBA Symposium (G. E. W. Wolstenholme and R. Porter, eds.), p. 181. London: Churchill 1966.
— W. D. Kelly, J. Roetstein, and L. R. Yarco: Immunological deficiency diseases. Agammaglobulinemia, hypogammaglobulinemia, Hodgkin’s disease, and sarcoidosis. In: Progress in allergy, Vol. 6, p. 187. Basel-New York: Karger 1962.
— R. D. A. Peterson, J. Finstad, and A. E. Gabrielsen: Morphologic studies of the development of the lymphoid tissues. Ser. Haemat. (Suppl. toScand. J. Haemat.) 8,1 (1965).
— J. Roetstein, and W. F. Mazzitello: The simultaneous occurrence of rheumatoid arthritis and agammaglobulinemia. J. Lab. clin. Med. 49, 343 (1957).
—, and R. L. Varco: Successful homovital transplantation in agammaglobulinemia. J. clin. Invest. 34, 910 (1955).
—— A clinical and experimental study of agammaglobulinemia. J. Lancet (Minneapolis) 75, 245 (1955).
—— Successful homograft of skin in a child with agammaglobulinemia. J. Amer. med. Ass. 157, 713 (1955).
—, and S. J. Zak: Disturbances in gamma globulin synthesis as „experiments of nature“. Pediatrics 18, 109 (1956).
Gowans, J. L.: The role of lymphocytes in the destruction of homografts. Brit. med. Bull. 21, 106 (1965).
—, and D. D. McGregor: The immunological activities of lymphocytes. Progr. allergy, Vol. 9, p. 1. Basel-New York: Karger 1965.
Grabar, P., P. Burtin et M. Seligmann: Etudes immuno-électrophorétiques et immuno-ehimiques des agammaglobulinémies. Étude clin. biol. 3, 41 (1958).
Grand Rounds University Hospital of Madison, 10. 2. 1967 (Stiehm): Agammaglobulinemia, defective delayed hypersensitivity, and ulcerative colitis.
Greaves, A. A.: Personal communication.
Gross, P. A. M., D. Gitlin, and Ch. A. Janeway: The gamma globulins and their clinical significance. III. Hypergammaglobulinemia. IV. Therapeutic uses of gamma globulins. New Engl. J. Med. 260, 121 and 170 (1959).
Grote, L. R., u. B. Fischer-Wasels: Über totale Alymphozytose. Münch, med. Wschr. 1929 II, 2040.
Grubb, R., and A. B. Laurell: Hereditary serological human serum groups. Acta path. microbiol. scand. 39, 390 (1956).
Gruber, G. B.: Über Variationen der Thymusform und -lage. Z. angew. Anat. Konstit.-Lehre 6, 320 (1920).
Hamilton, W. J., J. D. Boyd, and H. W. Mossman: Human embryology. 2. Ed. S. 190ff. Cambridge: W. Heffer & Sons, Ltd. 1952.
Hanson, L. A.: Aspects of the Abscence of the IgA System. 3rd Developmental Immunology Workshop, Sanibel (1967).
Hansson, O., and B. Vahlquist: Yaccinia gangrenosa and compound 33T57. Lancet 1963 II, 687.
Harboe, M., H. Pande, P. Brandtzaeg, K. J. Tveter, and P. F. Hjort: Synthesis of donor type γG-globulin following thymus transplantation in hypogammaglobulinemia with severe lymphopenia. Scand. J. Haemat. 3, 351 (1966).
Hathaway, W. E., R. W. Brangle, Th. L. Nelson, and I. E. Roeckel: Aplastic anemia and alymphocytosis in an infant with hypogammaglobulinemia: Graft-versus-host reaction? J. Pediat. 68, 713 (1966).
— J. H. Githens, W. R. Blackburn, V. Fulginiti, and C. H. Kempe: Aplastic anemia, histiocytosis and erythrodermia in immunologically deficient children. Probable human runt disease. New Engl. J. Med. 273, 953 (1965).
Haworth, J. C., J. Hoogstraten, and H. Taylor: Thymic alymphoplasia. Report of 13 cases and review of the literature. Arch. Dis. Child. 42, 40 (1967).
Hayles, A. B., G. B. Stickler, and B. F. McKenzie: Decrease in serum gamma globulin (Agammaglobulinemia). Pediatrics 14, 449 (1954).
Heremans, J. F., P. A. Crabbé, and P. L. Masson: Biological significance of exocrine γA-immuno-globulin. Acta med. scand., Suppl. 445, 179, 84 (1966).
Hess, M. W., H. Cottier, and R. D. Stoner: Primary and secondary antitoxin responses in thymectomized mice. J. Immunol. 91, 425 (1963).
Heurtematte, A., J. Roux, P. Balzinc et P. Mercier: Ataxie télangiectasie: une observation familiale. Pédiatrie 21, 720 (1966).
Hirschhorn, K., F. Bach, R. L. Kolodny, I. L. Firschein, and N. Hashem: Immune response and mitosis of human peripheral blood lymphocytes in vitro. Science N. S. 142, 1185 (1963).
— R. L. Kolodny, N. Hashem, and F. Bach: Mitogenic action of phytohaemagglutinin. Lancet 1963 II, 305.
— R. R. Schreibman, S. Verbo, and R. H. Gruskin: The action of streptolysin S on peripheral lymphocytes of normal subjects and patients with acute rheumatic fever. Proc. nat. Acad. Sci. (Wash.) 52, 1151 (1964).
Hitzig, W. H.: Praktische und theoretische Ergebnisse neuerer Bluteiweißuntersuchungen. Schweiz, med. Wschr. 90, 1149 (1960).
— Die Plasmaproteine in der klinischen Medizin. Ergebnisse spezifischer Bestimmungen mit besonderer Berücksichtigung immunochemischer Methoden. Berlin-Göttingen-Heidelberg: Springer 1963.
— Phénomène de Sanarelli-Shwartzman lors de syndrome par manque d’anticorps. Méd. et Hyg. (Genève) 21, 1106 (1963).
— Zur Laboratoriumsdiagnostik des Antikörpermangelsyndroms. Dtsch. med. Wschr. 90, 1721 (1965).
— Z. Bntó, H. Bosch, and H. J. Huser: Agammaglobulinämie und Alymphozytose mit Schwund des lymphatischen Gewebes. Helv. paediat. Acta 13, 551 (1958).
—, u. E. Gautier: Generalisiertes Sanarelli-Shwartzman-Phänomen bei Agammaglobulinämie. Proc. VIIth Internat. Congr. Haematol. Rome. Pensiero Scientifico (Roma, 1959).
— H. E. M. Kay, and H. Cottier: Familial lymphopenia with agammaglobulinemia. An attempt at treatment by implantation of foetal thymus. Lancet 1965 II, 151.
—, and A. Schlaepfer: Chronic neutropenia and dysgammaglobulinaemia. Possible interrelations. 10th Congr. Internat. Soc. Haemat. Stockholm 1964.
—, u. H. Willi: Hereditäre lympho-plasmocytäre Dysgenesie („Alymphocytose mit Agammaglobulinämie“). Schweiz, med. Wschr. 91, 1625 (1961).
Hollstrom, Y. E., and S. Hard: A fatality from BCG vaccination. Acta derm.-venereol. (Stoekh.) 33, 159 (1953).
Hong, R., W. K. Schubert, E. Y. Perrin, and C. D. West: Antibody deficiency syndrome associated with β2-macroglobulinemia. J. Pediat. 61, 831 (1962).
Hoyer, J., M. D. Cooper u. R. D. Good: Persönliche Mitteilung 1966.
Huntley, C. C., and M. C. Costas: Eosinophilia and agammaglobulinemia. Pediatrics 36, 425 (1965).
— J. W. Labterty, and A. Lyerly: Antibody deficiency syndrome with increased gamma1M (B2M) globulins and absent gamma1A (B2A) globulins and gamma2 (G) globulins. Pediatrics 32, 407 (1963).
Illig, R.: Experimentelle Untersuchungen über den Einfluß des Soors auf das lymphatische Blutbild der Ratten. Diss. med. Bern 1954.
Jamieson, W. M., and M. R. Kerr: A family with several cases of hypogammaglobulinemia. Arch. Dis. Child. 37, 330 (1962).
Janeway, Ch. A.: Hypo-gamma-globulinémie et again m aglobulinémie. In: Les gammaglobulines et la médecine des enfants. Paris: Masson 1955.
— L. Apt, and D. Gitlin: Agammaglobulinemia. Trans. Ass. Amer. Phys. 66, 200 (1953).
Jeune, M., F. Larbre, D. Germain et F. Freycon: Lymphocytophtisie, alymphocytose et hypogammaglobulinémie. Arch, franç. Pédiat. 15, 1 (1959).
— R. Schier, R. Carrón et F. Challut: Vaccine tardivement généralisée et développée sur un eczéma apparu postérieurement à la vaccination. (Etudes cliniques, biologiques et pathogéniques.) Presse méd. 63, 962 (1955).
Kadowaki, J., R. I. Thompsen, W. W. Zuelzer, P. Y. Woolley jr., A. J. Brough, and D. Gruber: XX/XY lymphoid chimaerism in congenital immunological deficiency syndrome with thymic alymphoplasia. Lancet 1965 II, 1152.
Karpati, G., A. H. Eisen, E. Andermann, H. L. Bacal, and P. Robb: Ataxia-telangiectasia. Amer. J. Dis. Child. 110, 51 (1965).
Kay, H. E. M.: Concepts of cellular deficiency and replacement therapy in agammaglobulinemia. 3rd Developmental Immunology Workshop, Sanibel (1967).
— J. H. L. Playtair, M. R. Woleendale, and P. K. Hopper: Nature (Lond.) 196, 238 (1962).
— M. R. Woleendale, and J. H. L. Playeair: Properties of leucocytes of blood and lymphoid organs in the human foetus. Int. Congr. Haemat. Stockholm 1964.
Keidan, S. A., K. McCarthy, and J. C. Haworth: Eatal generalized vaccinia with failure of antibody production and absence of serum gamma globulin. Arch. Dis. Child. 28, 110 (1953).
Kempe, C. H.: Studies on smallpox and complications of smallpox vaccination. Pediatrics 26, 176 (1960).
Kleihauer, E., u. H. Noltenius: Unbeeinflußbares Antikörpermangelsyndrom bei einem jungen Säugling. Tgg. Südwestdtsch. Kinderärzte, Saarbrücken, 11./12. 6. 1960.
Koch, E., G. W. Schmidt u. E. Doll: Beitrag zur Agammaglobulinämie im Kindesalter. Mschr. Kinderheilk. 105, 211 (1957).
Kosenow, W., u. N. Schuemmelfeder: Allgemeiner Lymphozytenschwund (Lymphozyto-phthise). Ein Beitrag zur Pathologie des frühen Kindesalters. Klin. Wschr. 31, 1022 (1953).
Kouvalainen, K.: Significance of Hassal’s corpuscles in the light of their morphological and histoehemieal appearance. Ann. Med. exp. Fenn. 42, 177 (1964).
— Persönliche Mitteilung 1965.
KoziNN, P. J., M. M. Sigel, and R. Gorrie: Progressive vaccinia associated with agammaglobulinemia and defects in immune mechanism. Pediatrics 16, 600 (1955).
Krecke, H.-J.: Zum generalisierten Shwartzman-Phänomen und seiner Bedeutung für die menschliche Pathologie. Stuttgart: Eischer 1964.
Kulneff, N., K. O. Pedersen u. J. Waldenstroem: Drei Eälle von Agammaglobulinämie. Ein klinischer, genetischer und physikalisch-chemischer Beitrag zur Kenntnis des Protein-Stoffwechsels. Schweiz, med. Wschr. 85, 363 (1955).
Lamy, M., M.-L. Jammet, E. Martin et B. Dejoulx: L’ataxie-télangieetasie. Arch, franç. Pédiat. 21, 645 (1964).
Landolt, R. A., G. Mueller u. W. H. Hitzig: Kongenitale Alymphozytose (NÉzelof). Helv. paediat. Acta, im Druck.
Lang, N., G. Schettler u. R. Wildhack: Über einen Fall von „Agammaglobulinämie“ und das Verhalten parenteral zugeführten radioaktiv markierten Gammaglobulins im Serum. Klin. Wschr. 32, 856 (1954).
Larson, D. L., and L. J. Tomlinson: Quantitative antibody studies in man: II. The relation of the level of serum proteins to antibody production. J. Lab. clin. Med. 39, 129 (1952).
Lasch, H. G., H. J. Krecke et A. Bohle: Physiopathologie du phénomène de Sanarelli-Shwartzman. Méd. et Hyg. (Genève) 21, 1099 (1963).
Laski, B., A. Sass-Kortsak, and D. A. Hileman: Cyclic neutropenia and agammaglobulinemia. Amer. J. Dis. Child. 88, 820 (1954).
Leroy, D., J. Bizais, M. E. Richier-Chevrel et J. L. Richier: Une épidémie humaine de cow-pox en Bretagne. Sem. Hôp. Paris 29, 1182 (1953).
Lewis, H. M., and E. C. Johnson: Eatal agammaglobulinemic progressive vaccinia. Arch. Derm. 75, 837 (1957).
Linnet-Jepsen, P.: Serum groups in the newborn. Proc. 6th Congr. Europ. Soc. Haemat. Copenhagen 1957. Basel: Karger 1958.
Lobdell, D. H.: Congenital absence of the parathyroid glands. Arch. Path. 67, 412 (1959).
Louis-Bar, E.: Sur un syndrome progressif comprenant des télangiectasies capillaires cutanées et conjonetivales symétriques, à disposition naevoide et des troubles cérébelleux. Confin. neurol. (Basel) 4, 32 (1941/42).
Loutit, J. E.: Immunological and trophic functions of lymphocytes. Lancet 1962 II, 1106.
Mardarowicz, C., i R. Malec: Vaccinia generalisata. Pol. Tyg. Lek. 19, 1249 (1964).
Marshall, W. C., H. J. Weston, and M. Bodian: Pneumocystis Carinii pneumonia and congenital hypogammaglobulinemia. Arch. Dis. Child. 39, 18 (1964).
Martin, C. M., E. Bronstein, and S. Dray: Agammaglobulinemia: clinical staff conference at the National Institutes of Health. Ann. intern. Med. 47, 533 (1957).
Martin, N. H.: Agammaglobulinemia. A congenital defect. Lancet 1954 II, 1094.
Matsaniotis, N., E. Apostolopoulou, and J. Vlachos: Thymic alymphocytosis. Report of a case with normal Peyer’s patches. J. Pediat, 69, 576 (1966).
Mazzitello, W. F., and R. A. Good: The clinical problem of agammaglobulinemia. Postgrad. Med. 20, 95 (1956).
McKusick, V. A., and H. E. Gross: Ataxia-telangiectasia and Swiss-type agammaglobulinemia. Two genetic disorders of the immune mechanism in related Amish sibships. J. Amer. med. Ass. 195, 739 (1966).
McNiel, J. R.: Progressive vaccinia. Case report in a newborn infant with lymphopenia. Clin. Pediat. 4, 539 (1965).
Metcalf, D.: The thymus and its role in immunity and carcinogenesis. Med. J. Aust. 1, 225 (1965).
Miller, J. F. A. P.: Immunological function of the thymus. Lancet 1961 II, 748.
— The thymus and transplantation immunity. Brit. med. Bull. 21, 111 (1965).
—, u. P. Dukor: Die Biologie des Thymus nach dem heutigen Stande der Forschimg. Basel-New York: Karger 1964.
— A. H. E. Marshall, and R. G. White: The immunological significance of the thymus. Advances Immunology, Yol. 2, p. 111. New York-London: Academic Press 1962.
Miller, M. E.: Graft versus host reactions in immunologic deficiency with special reference to thymic dysplasia. 3rd Developmental Immunology Workshop, Sanibel (1967).
—, and K. Hummeler: Morphologic and functional observations on a case of thymic dysplasia (“Swiss agammaglobulinemia”). J. Pediat. 70, 737 (1967).
—, and R. M. Schieken: Thymic dysplasia. A separable entity from “Swiss agammaglobulinemia” J. Pediat. (in press).
Moullec, J., R. Kherumian, E. Sutton et P. Espagnon: Contribution à l’étude du facteur de groupe Gma du plasma humain. Rev. Hémat. 11, 512 (1956).
Nezelof, C., M.-L. Jammet, P. Lortholary, B. Labrune et M. Lamy: L’hypoplasie héréditaire du thymus. Arch, franç. Pédiat. 21, 897 (1964).
Nomenclature for Human Immunoglobulins: Bull. Org. mond. Santé 30, 447 (1964); Int. Arch. Allergy 25, 242 (1964).
O’Connell, E. J., P. Enriquez, J. W. Linman, G. J. Gleich, and F. C. McDuffie: Swiss-type agammaglobulinemia associated with an abnormality of the inflammatory response. 36th Ann. Meet. Soc. Ped. Research, Atlantic City, N. J., April 1966.
Page, A. R., A. E. Hansen, and R. A. Good: Occurrence of leukemia and lymphoma in patients with agammaglobulinemia. Blood 21, 197 (1963).
Patten, B. M.: Human embryology. Philadelphia-Toronto: Blakiston 1947.
Peterson, R. D. A.: Ataxia telangiectasia. 3rd Developmental Immunology Workshop, Sanibel (1967).
— M. D. Cooper, and R. A. Good: Lymphocytic malignancies: a new perspective. Meet. Amer. Ped. Soc., Philadelphia, May 1965.
—— Disorders of the thymus and other lymphoid tissues. In: Progress in Medical Genetics, vol. IV, p. 1. (Ed. A. G. Steinberg, and A. G. Bearn). New York-London: Grane & Stratton 1965.
—, and R. A. Good: Morphologic and developmental differences between the cells of the chicken’s thymus and Bursa of Fabricius. Blood 26, 269 (1965).
— W. D. Kelly, and R. A. Good: Ataxia-telangiectasia. Its association with a defective thymus, immunologieal-deficiency disease, and malignancy. Lancet 1964 I, 1189.
Pierret, R., C. Huriez, F. Demons et G. Fontaine: Vaccine grave chez des nourrissons eczémateux. Considérations cliniques et épidémiologiques. Lille méd., 3e sériel, 237 (1956).
Porter, H. M.: Immunologic studies in congenital agammaglobulinemia with emphasis on delayed hypersensitivity. Pediatrics 20, 958 (1957).
Ramon-Guerra, A. J., C. A. Queirolo e N. Temesio: Sindromo de becegeitis grave, moniliasis extensiva e hipogammaglobulinemia familiar. Arch. Pediat. Urug. 29, 618 (1958).
Reed, W. B., W. L. Epstein, E. Boder, and R. Sedgwick: Cutaneous manifestations of ataxia-telangiectasia. J. Amer. med. Ass. 195, 746 (1966).
Regamey, E.: Crise aigue de purpura thrombopénique consécutive à une généralisation vaccinale tardive. Schweiz. med. Wschr. 70, 697 (1940).
Reynolds, E. O. R.: A fatal case of eczema vaccinatum. Lancet 1960 II, 684.
Robbins, J. B., R. H. Miller, V. M. Arean, and H. A. Pearson: Successful treatment of Pneumocystis Carinii Pneumonitis in a patient with congenital hypogammaglobulinemia. New Engl. J. Med. 272, 708 (1965).
Rockey, J. H., L. A. Hanson, J. F. Heremans, and H. G. Kunkel: Beta2A aglobulinemia in two healthy men. J. Lab. clin. Med. 63, 205 (1964).
Rodgers, T. S., and M. H. K. Haggie: Pneumocystis Carinii Pneumonia associated with hypogammaglobulinemia responding to pentamidine. Lancet 1964 I, 1042.
Romagny, G., P. Joffard et G. Dorsit: Nouvelle observation d’ataxie-télangiectasie. Syndrome choréo-athétosique prédominant. Bronchectasie. Hypogammaglobulinémie progressive. Pédiatrie 20, 468 (1965).
Rosen, F. S., D. Gitlin, and C. A. Janeway: Alymphocytosis, agammaglobulinemia, homo-grafts, and delayed hypersensitivity: study of a case. Lancet 1962 II, 380.
— S. P. Gotoff, J. M. Craig, J. Ritchie, and Ch. A. Janeway: Further observations on the Swiss type of agammaglobulinemia (alymphocytosis). New Engl. J. Med. 274, 18 (1966).
— S. V. Kevy, E. Merler, C. A. Janeway, and D. Gitlin: Dysgammaglobulinemia and recurrent bacterial infection. Lancet 1961 I, 700.
Rosenthal, I. M., A. S. Markowitz, and R. Medenis: Immunologic incompetence in ataxia-telangiectasia. Amer. J. Dis. Child. 110, 69 (1965).
Roessle, R.: Über gleichzeitige Mißbildungen der branchiogenen Organe und über angeborenen Mangel der Epithelkörperehen. Virchows Arch. path. Anat. 283, 41 (1932).
— Über den angeborenen Mangel der Epithelkörperchen. Schweiz. med. Wschr. 19, 848 (1938).
—, u. E. Roulet: Maß und Zahl in der Pathologie. Berlin-Wien: Springer 1932.
Ruth, R. E., E. O. Hohn, and G. R. J. Law: Ontogeny of the lymphoid tissue. Ser. Haemat. (Suppl. to Scand. J. Haemat.) 8, 29 (1965).
Sabesin, S. M.: Lymphocytes of small mammals: spontaneous transformation in culture of blastoids. Science 149, 1385 (1965).
Sacrez, R., D. Willard, P. Beauvais et R. Korn: Etude des troubles digestifs et respiratoires dans un cas de lymphocytophtisie du nourrisson. Arch, franç. Pédiat. 20, 401 (1963).
Scheidegger, J. J.: L’immuno-électrophorèse. Sem. Hôp. Paris 32, 2119 (1956).
— E. Martin et G. Riotton: L’apparition des diverses composantes antigéniques du sérum au cours du développement foetal. Schweiz, med. Wschr. 86, 224 (1956).
Schlaepfer, A., u. W. H. Hitzig: Die immunochemische Untersuchung des Antikörpermangelsyndroms (AMS). Schweiz, med. Wschr. 92, 1347 (1962).
Schorn, J.: Über die Lymphocytophthise des Säuglings. Verh. dtsch. path. Ges. 40, 291 (1956).
Schubert, W. K., R. Fowler, L. Martin, and C. D. West: Studies of homograft survival in children with inborn errors of protein metabolism associated with increased susceptibility to infection. Soc. Pediatr. Res., 30th Ann. Meeting, 1960.
Sédaillan, P., A. Badon, J. Eayolle et M. Rouchon: Vaccine généralisée mortelle avec virémie et agammaglobulinémie. Presse méd. 65, 319 (1957).
Seligmann, M., et J. Badin: Béta2-macroglobulinémie familiale. Rev. franç. Étud. clin. biol. 7, 1107 (1962).
Shuster, J., Z. Hart, C. W. Stimson, A. J. Brough, and M. D. Poulik: Ataxia telangiectasia with cerebellar tumor. Pediatrics 37, 776 (1966).
Silverstein, A. M.: Congenital syphilis and the timing of immunogenesis in the human foetus. Nature (Lond.) 194, 196 (1962).
Simonsen, M.: Recent experiments on the graft-versus-host reaction in the chick embryo. Brit. med. Bull. 21, 129 (1965).
Somers, K.: Vaccinia gangrenosa and agammaglobulinemia. Arch. Dis. Child. 32, 220 (1957).
Soothill, J. E.: The concentration of γ-globulin and γ-macroglobulin in the serum of patients with hypogammaglobulinemia. Proc. roy. Soc. Med. 55, 395 (1962).
Squire, J. R.: Hypogammaglobulinemia in Great Britain. Acta haemat. (Basel) 24, 99 (1960).
— Hypogammaglobulinemia in the United Kingdom, 1956–1961. Proc. roy. Soc. Med. 55, 393 (1962).
Stoelinga, G. B. A.: Dysimmunoglobulinaemie bij kinderen. Nijmegen: Centrale Drukkerij 1966.
Szenberg, A., and N. L. Warner: Dissociation of immunological responsiveness in folws with a hormonally arrested development of lymphoid tissues. Nature (Lond.) 194, 146 (1962).
Tadjoedin, M. K., and F. C. Fraser: Heredity of ataxia-telangiectasia (Louis-Bar Syndrome). Amer. J. Dis. Child. 110, 64 (1965).
Taitz, L. S., C. Zarate-Salvador, and E. Schwartz: Congenital absence of the parathyroid and thymus glands in an infant. (HI and IV Pharyngeal Pouch Syndrome). Pediatrics 38, 412 (1966).
Tobler, R., u. H. Cottier: Familiäre Lymphopenie mit Agammaglobulinämie und schwerer Moniliasis. Die „essentielle Lymphocytophthise“ als besondere Form der frühkindlichen Agammaglobulinämie. Helv. Paediat. Acta 13, 313 (1958).
de Vaal, O. M., and V. Seynhaeve: Reticular dysgenesia. Lancet 1959 II, 1123.
Varco, R. L., L. D. MacLean, J. B. Aust, and R. A. Good: Agammaglobulinemia: an approach to homovital transplantation. Ann. Surg. 142, 334 (1955).
Veslot, J., C. NÉzelof et P. Villemin: Bécégite mortelle, agammaglobulinémie, alympho-plasmocytose et hypoplasie thymique. Arch, franç. Pédiat. 23, 1113 (1966).
Villemin, P.: Alymphocytose et risque vaccinal. Thèse méd., Paris 1965.
Vivell, O.: Persönliche Mitteilung 1965.
Volkman, A., and J. L. Gowans: The production of macrophages in the rat. Brit. J. exp. Path. 46, 50 (1965).
—— The origin of macrophages from bone marrow in the rat. Brit. J. exp. Path. 46,62 (1965).
de Vries, M. J., and L. J. Dooren: Graft versus host or autoimmune lesions in Swiss type agammaglobulinemia. Their relation to a deficient development of the thymic epithelium. 3rd Developmental Immunology Workshop, Sanibel (1967).
Waldmann, Th. A.: Kinetic studies of immunoglobulin metabolism in immunologic deficiency. 3rd Developmental Immunology Workshop, Sanibel (1967)
Wallgren, A.: Einige Probleme der Calmetteschen Impfung. Dtsch. med. Wschr. 86,105(1961).
Warner, N. L., and A. Szenberg: Immunologic studies on hormonally burseetomized and surgically thymectomized chickens: dissociation of immunologic responsiveness. In: The Thymus in Immunbiology (Good, R. A., and A. E. Gabrielsen, eds.), pp. 395–411. New York: Hoeber & Harper 1964.
— and F. M. Burnet: The immunological role of different lymphoid organs in the chicken. I. Dissociation of immunological responsiveness. Aust. J. exp. Biol. Sci. 40, 373 (1962).
White, C. M.: Vaccinia gangrenosa due to hypogammaglobulinaemia. Lancet 1963 I, 969.
— Vaccinia gangrenosa. Lancet 1963 I, 1162.
Wiener, A. S., and E. B. Gordon: Studies on human serum gamma globulin. I. Half-life and rate of production. J. Lab. clin. Med. 49, 258 (1957).
Wilson, R., K. Sjodin, and M. Bealmear: The absence of wasting in thymectomized germ-free (Axenic) mice. Proc. Soc. exp. Biol. (N. Y.) 117, 237 (1964).
Wiskott, A.: Familiärer, angeborener Morbus Werlhofü? Mschr. Kinderheilk. 68, 212 (1937)
Wolfe, J. A.: Wiskott-Aldrich syndrome: Clinical, immunologic, and pathologic observations. J. Pediat. 70, 221 (1967).
Wollheim, F.: Inherited “acquired” hypogammaglobulinemia. Lancet 1961 I, 316.
Yakovac, W. C.: Thymic dysplasia in congenital agammaglobulinemia. J. Pediat. 63, 699 (1963).
Yamamoto, H.: Reversible transformation of lymphocytes in human leucocyte cultures. Nature (Lond.) 212, 997 (1966).
Zoethout, H. E.: Persönliche Mitteilung 1966.
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Hitzig, W.H., Barandun, S., Cottier, H. (1968). Die schweizerische Form der Agammaglobulinämie. In: Heilmeyer, L., Prader, A., Muller, AF., Schoen, R. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde. Ergebnisse der Inneren Medizin und Kinderheilkunde, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-95016-2_3
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