Zusammenfassung
Die radikale Entfernung der Bauchspeicheldrüse beim Menschen ist in mehrfacher Hinsicht problematisch: Die versteckte Lage der Drüse und ihre nahe topographische Beziehung zu anderen Organen und vor allem zu den großen Gefäßen bedingt operativ-technische Schwierigkeiten besonderer Art. Die Verhältnisse der regionalen Gefäßversorgung zwingen in der Regel zur Mitnahme weiterer Organe wie des Duodenums, der Milz und eines Teiles des Magens, was den Eingriff zu einem der schwersten in der gesamten Chirurgie macht. Der Ausfall der inkretorischen und exkretorischen Funktion der Bauchspeicheldrüse bedarf einer dauernden und sehr sorgfältigen Substitutionstherapie. Obwohl die rein technischen Fragen der Operation schon vor über 50 Jahren gelöst erschienen, ermöglichten erst die neueren Fortschritte der Schock- und Infektionsbekämpfung, der Anaesthesie und vor allem der Stoffwechselforschung eine häufigere Vornahme derartiger Eingriffe.
Aus der Medizinischen Universitätsklinik (Direktor: Prof. Dr. Dr. h. c. L. Heilmeyer) und der Chirurgischen Universitätsklinik (Direktor: Prof. Dr. H. Krauss), Freiburg i. Br.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatur
Abel, F.: Rare tumors, etiology and localisation. J. Internat. Coll. Surg. 12, 673 (1949).
Abu-Zircky, A.: Total pancreatectomy for ampullary carcinoma. Report of a case. J. Egypt. Med. Ass. 40, 793–800 (1957).
Albritten, F. F.: Recurring pancreatitis and associated stenosis of the common bile duct. Arch. Surg. (Chicago) 67, 779–789 (1953).
Allan, F. N., D. F. Bowie, J. J. R. Macleod and W. L. Robinson: Behavior of depan–creatized dogs kept alive with insulin. Brit. J. exp. Path. 5, 75–83 (1924).
D’aunoy, R., M. A. Ogden and B. Halpern: Carcinoma of the pancreas. Amer. J. Path. 15, 217–224 (1939).
Baird, C. W., and J. Bornstein: Plasma–insulin and insulin resistance. Lancet 1957 I, 1111 to 1113.
Balzer, E., U. K. Werner: Untersuchungen über die Eignung von Fermentpräparaten für die Substitution von Pankreasfermenten. Med. Klin. 1953, 1036–1038.
Banzet: Diskussionsbemerkung zu Rudler: Mém. Acad. Chir. 77, 198 (1951).
Baranger, Delangre Et Boudot: Cancer de la 2e portion du Duodénum. Ablation d’une partie du duodénum et pancréatectomie totale. Mém. Acad. Chir. 77, 681–684 (1951).
Barclay, S.: The relief of chronic recurring pancreatitis. Brit. med. J. 1955, 4935, 363–364.
Barker, W. F., K. E. Rogers and F. D. Moore: Effect of pancreatectomy on phospholipid synthesis in dog. Arch. Surg. (Chicago) 61, 1151–1162 (1950).
Barrett, D., and W. F. Bowers: Total pancreatectomy for chronic relapsing pancreatitis and calcinosis of the pancreas. U. S. armed Forces med. J. 8, 1037–1045 (1957).
Bartelheimer, H., U. J. M. Schmitt-Rohde: Osteoporese als Krankheitsgeschehen. Ergebn. inn. Med. Kinderheilk. 7, 454–585 (1956).
Bartlett, M. K.: The status of pancreaticoduodenal resection. Surg. Clin. N. Amer. 27, 1032–1036 (1947).
Beck, K.: Unveröffentlichte Untersuchungen.
Becker, D., and M. Miller: Presence of diabetic glomerulosclerosis in patients with hemo–chromatosis. N. Engl. J. Med. 263, 367–373 (1960).
Becker, W. F.: Pancreatoduodenectomy for carcinoma of the pancreas in an infant. Report of a case. Ann. Surg. 145, 170–172 (1957).
Becker, W. H., U. H. Nusselt: Über einige bemerkenswerte Beobachtungen beim Hyper– insulinismus. Dtsch. med. Wschr. 1951, 1613.
Belding, H. H.: A new method for biopsy of lesions on the head of the pancreas. J. Amer. med. Ass. 1954, 155, 123.
Bell, E. T.: Carcinoma of the pancreas. Amer. J. Path. 83, 499–523 (1957).
Belsky, H., and N. W. Cornell: Disseminates focal fat necrosis following radical pancreatico-duodenectomy for acinous carcinoma of the head of the pancreas. Ann. Surg. 141, 556–562 (1955).
Bennett, L. C.: Carcinoma of the ampulla of Vater. Whipple operation and ten–year–arrest in three cases. Calif. Med. 76, 289 (1952).
Berg, B. N., and T. F. Zucker: Liver changes after deprivation of external pancreatic secretion. Proc. Soc. exp. Biol. (N. Y.) 29, 68–70 (1931).
Bergen, St. S. Jr., and W. S. Norton: Clinical and metabolic effects of phenylbiguanide. Dianetes 9, 183–185 (1960).
Best, C. H., C. C. Ferguson and J. M. Hershey: Cholin and liver fat in diabetic dogs. J. Physiol. (Lond.) 79, 94 (1933).
Billroth, Th.: Zit. n. Cattel and Warren.
Bing and Fawcett: Zit. bei Brunschwig, A. (1949a).
Biondi: Clinica chirurgica 4, 1896. Zit. n. Körte.
Bornstein, J., and R. D. Lawrence: Plasma-insulin in human diabetes mellitus. Brit. med. J. 1951, 4747; 1541–1544.
Bornstein, J.: Insulin-reversible inhibition of glucose utilization by serum lipoprotein fractions. J. biol. Chem. 205, 513 (1953).
Bornstein, J., and C. R. Park: Inhibition of glucose uptake by serum lipoprotein fractions. J. biol. Chem. 205, 503 (1953).
Bowden, L.: The fallibility of pancreatic biopsy. Ann. Surg. 139, 403–408 (1954).
Bowden, L., and G. N. Papanicolaou: Exfoliated pancreatic cancer cells in the duct of Wirsung. Ann. Surg. 150, 296–298 (1959).
Bowers, R. F.: Surgical therapy for chronic pancreatitis. Surgery 30, 116–129 (1951).
Briggs,: Zit. n. Körte. St. Louis Med. J. 1890, 154.
Brintnall, E. S.: An evaluation of surgical treatment of carcinoma of the head of the pancreas. Cancer 5, 908–910 (1952).
Brintnall, E. S.: Technical considerations in resection of the head of the pancreas. Surg. Gynec. and Obstet. 95, 181–183 (1952).
Brunschwig, A.: Univ. Chicago Press 1947, 324.
Brunschwig, A.: Pancreato-total gastrectomy and splenectomy for advanced carcinoma of the stomach. Cancer 1, 427–430 (1948).
Brunschwig, A.: Neue Fortschritte in der Behandlung des Pankreascarcinoms. Krebsarzt 1947, 2 /11, 510–511.
Brunschwig, A.: Radical pancreatectomy and splenectomy with left total pneumectomy at one sitting for sarcoma of the pancreas and pulmonary metastases. Cancer 2, 576–580 (1949 a).
Brunschwig, A.: Results of pancreatoduodenectomy. Cancer 2, 763–766 (1949b).
Brunschwig, A: Reoperation following pancreatoduodenectomy. Cancer 8, 624–628 (1950).
Brunschwig, A.: Pancreatoduodenectomy: A “curative” operation for malignant neoplasms in the pancreatoduodenal region. Report of three over-five-year survivors. Ann. Surg. 136, 610–624 (1952).
Brunschwig, A.: Radical pancreatoduodenectomy for cancer of the head of the pancreas. Cancer 9, 1160–1162 (1956).
Brunschwig, A.: Operationen Am Pankreas. Breitner U. A. Operations-Lehre Iii, 10. Wien-München: Urban and Schwarzenberg 1958.
Brunschwig, A., and F. Gentil: Postoperative diabetes mellitus following resection of the body and tail of the pancreas for secondary invasion by gastric cancer. Ann. Surg. 130, 921–928 (1949).
Burton, T. Y., T. P. Kearns and E. H. Rynearson: Diabetic retinopathy following total Pancreatectomy. Proc. Mayo Clin. 32, 735–739 (1957).
Carlson, R. J.: The problem of diagnosis at the time of operation in tumors of the head of the Pancreas. Surgery 28, 672–679 (1950).
Castiglioni, G. C., U. E. Pizzecco: Möglichkeiten und Grenzen chirurgischer Radikaleingriffe Bei Pankreaskopf- Und Papillencarcinom. Zbl. Chir. 84, 1462–1471 (1959).
Cattell, R. B.: The surgical treatment of carcinoma of the pancreatoduodenal area. Ann. Roy. Coll. Surg. (Engl.) 4, 197–205 (1949).
Cattell, R. B., and L. J. Pyrtek: An appraisal of pancreatoduodenal resection. A follow-up-study of 61 cases. Ann. Surg. 129, 840–849 (1949).
Cattell, R. B., and K. W. Warren: Surgery of the pancreas. Philadelphia: W. B. Saunders Comp. 1954.
Cattell, R. B., and W. C. Young: Long survival in a case of carcinoma of the pancreas. Lahey Clin. Bull. 10, 131–134 (1957).
Chandler, G. N., and M. C. Oldfield: Total pancreatectomy. Brit. J. Surg. 45, 263–266 (1957).
Chapman, H. S.: Surgery of the pancreas. Div. III. West. J. Surg. 58, 178–187 (1950).
Child, C. G., and J. T. ELLIS: Radical pancreaticoduodenectomy. Report of two autopsies performed five and four years after operation. Ann. Surg. 134, 80–87 (1951).
Child, C. G., G. R. Holswade, R. D. Mc Clure Jr., A. L. Gore and E. A. O’neill: Pancreaticoduoden-ectomy with resection of the portal vein in the macaca mulatta monkey and in man. Surg. Gynec. and Obstet. 94, 31–45 (1952).
Clagett, R. B.: The surgical treatment of carcinoma of the pancreatoduodenal area. Ann. roy. Coll. Surg. (Engl.) 4, 197–205 (1949).
Cliffton, E. E.: Carcinoma of pancreas. Symptoms, signs and results of treatment in one Hundred Twenty-Two Cases. Arch. Surg. (Chicago) 65, 290–306 (1952).
Codivilla: Zit. n. Hess.
Coffey, R. C.: Pancreato-enterostomy and pancreatectomy. A preliminary report. Ann. Surg. 50, 1238–1264 (1909).
Coffey, F. L., G. F. Woelfel, K. J. David and M. G. Burdette: Treatment of chronic Relapsing Pancreatitis. Amer. Surg. 21, 569–576 (1955).
Collip, J. B., H. Selye and A. Neufeld : Experimental pancreatic diabetes in the monkey.Amer. J. Physiol. 119, 289–290 (1937).
Comfort, N. W.: Treatment of pancreatitis. Arch, intern. Med. 95, 735–738 (1955).
Cook, E. T., J. A. Dye and Mccandless: Pancreatic diabetes in the calf. Amer. J. Physiol. 156, 349–354 (1949).
Cox, R. W., E. D. Henley, E. B. Fergus and R. H. Williams: Sulfonylureas and diabetes Mellitus. I. Clinical Evaluation. Diabetes 5, 358–365 (1956A).
Creutzfeldt, W., F. Kümmerle U. E. Kern: Beobachtungen an vier Patienten mit totaler Pankreatektomie wegen eines Karzinoms des Pankreas. Dtsch. med. Wschr. 1959, 541–549.
Creutzfeldt, W., U. H. D. Söling: Orale Diabetestherapie und ihre experimentellen Grundlagen. Ergebn. inn. Med. Kinderheilk. N. F. 15, 1–213 (1960).
Deane: Zit. bei Gruber, G. B.: Kapitel über Pankreas im Handbuch für spezielle patho-logische Anatomie und Histologie, Bd. 5. Herausgegeben von H. Henke U. O. Lubarsch. Berlin 1929.
Dennis, C., and R. L. Varco: Survival of more than five years after pancreatoduodenectomy for Cancer Of The Ampulla and Pancreatic Head. Surgery 39, 92–106 (1956).
Desjardins, A.: Technique de la pancreatectomie. Rev. Chir. (Paris) 35, 945–973 (1907).
Desjardins, A.: Zit. bei W. HESS.
Diaz, C. J.: Klinische und pathogenetische Aspekte der primären Steatorrhoen. Schweiz, med. Wschr. 89, 447–452 (1959).
Dill-Russell, A. S.: Pancreaticogastrostomy. Lancet 1952, 589.
Dituri, B.: Insulin-resistant diabetes after total pancreatectomy. Report of a case. New Engl. J. Med. 251, 13–16 (1954).
Dixon, C. F., M. W. Comfort, A. L. Lichtman and R. E. Benson: Total pancreatectomy for carcinoma of the pancreas in a diabetic person. Arch. Surg. (Chicago) 52, 619–639 (1946). Ergebnisse d. inn. Medizin, N. F., Bd. 16 6
Dolger, H.: Clinical evaluation of vascular damage in diabetes mellitus. J. Amer. med. Ass. 134, 1289 (1947).
Doubilet, H., and J. H. Mulholland: Operative contrast visualisation of pancreatic diseases. Surg. Clin. N. Amer. 1956, 385–403.
Dragstedt, L. R., J. Van Prohaska and H. P. Harms: Observations on the substance in pancreas (a fat metabolizing hormone) which permits survival and prevents liver changes in depancreatized dogs. Amer. J. Physiol. 117, 175–181 (1936).
Dragstedt, L. R., J. Van Prohaska and H. P. Harms: Some physiologic problems in surgery of pancreas. Ann. Surg. 118, 576–593 (1943).
Dragstedt, L. R., J. G. Allen and E. M. Smith: Extensive insulin tolerance in diabetic dogs. Proc. Soc. exp. Biol. (N. Y.) 54, 292 (1943).
Dragstedt, L. R., J. S. Clarke, G. R. Rogers and P. V. Harper Jr.: Effects of feeding autoclaved pancreas to depancreatized and ductligated dogs. Amer. J. Physiol. 177, 95 (1954).
Dubost, C., E. Bernier, J. Guery Et Stoicoiu: Un cas de pancréatectomie totale pour cancer de la tête de pancréas. Rev. Chir. (Paris) 70, 105–117 (1951).
Duncan, L. J. P., A. Mcfarlane and J. S. Robson: Diabetic retinopathy and nephropathy in pancreatic diabetes. Lancet 1958, 822–826.
Dunlop, D. M.: Zit. nach Duncan U. Mitarb.
Duval, M. R.: Caudal pancreaticojejunostomy for chronic pancreatitis; operative criteria and technique. Surg. Clin. N. Amer. 1956, 831–839.
Everson, T. C., and W. H. Cole: Ten-year survival following pancreaticoduodenectomy for carcinoma of the ampulla of Vater (case report). Surgery 37, 260–262 (1955).
Eijsbouts, Q. A. M.: Pancreatico-duodenectomie. Academisch Proefscrift Utrecht 1956. Helmond 1956.
Fajans, St. S., L. H. Louis, H. S. Seltzer, R. D. Gittler, A. R. Hennes, B. L. Wajchen-Berg, I. P. Ackermann and J. W. Conn: Metabolic effects of arylsulfonylurea compounds in normal men and in diabetic subjects. Metabolism 5, 820–839 (1956).
Fallis, L. S., and D. E. Szilagyi: Observations on some metabolic changes after total pan–creatoduodenectomy. Ann. Surg. 128, 639–667 (1948).
Feather, H. E., and C. L. Kuhn: Total pancreatectomy for sarcoma of the pancreas. Ann. Surg. 184, 904–912 (1951).
Flörcken, H.: Operation eines Sarkoms des Pankreas. Zbl. Chir. 1953, 503–506.
Fowweather, F. S.: Determination of the amount and the composition of the fat of faeces. Investigation of a “wet” method and comparison with the “dry” method. Brit. J. exp. Path. 7, 7–14 (1926).
Franke, F.: Über die Exstirpation der krebsigen Bauchspeicheldrüse. Arch. klin. Chir. 64, 364–392 (1901).
Frazer, A. C.: The absorption of triglyceride fat from the intestine. Physiol. Eev. 26, 103–119 (1946)
Fritsch, A.: Uber differentialdiagnostische Schwierigkeiten im Gebiet des Pankreaskopfes. Wien. klin. Wschr. 1957, 13–15.
Gaston, E. A.: Total pancreatectomy. New Engl. J. Med. 288, 345–354 (1948).
Goetz, F. C., A. S. Gilbertsen and V. Josephson: Acute effects of orinase on peripheral glucose utilization. Metabolism 5, 788–800 (1956).
Goldner, M. G., and D. E. Clark: Insulin requirement of man after total pancreatectomy. J. clin. Endoer. 4, 194–197 (1944).
Gombkötö, B.: Zit. bei Flörcken, H.
Gottlob, R.: Vortäuschung eines Pankreaskopfcarcinoms durch eine gutartige Choledochus- striktur. Klin. Med. (Wien) 10, 466–470, 1955.
Gotjrevitch, A., and A. G. W. Whitfield: Total pancreatectomy. Brit. J. Surg. 40, 104–107 (1952).
Greenfield, J., and J. H. Sanders: Total pancreatectomy with report of postoperative physiologic studies. Surgery 25, 824–838 (1949).
Gross : Zit. im Addendum zur Arbeit von W. F. Becker.
Grossman, M. I., and P. H. Jordan: The Radio-jodinated triolein test for steatorrhea. Gastroenterology 34, 892–900 (1958).
Grttber, G. B.: Pathologie der Bauchspeicheldrüse in Henke–Lubarsch, Handbuch der speziellen pathologischen Anatomie. Berlin: Springer 1929. Bd. V, 2.
Halsted, W. S.: Contributions to the surgery of the bilepassage. Boston med. surg. J. 141, 645–654 (1899).
Halsted, W. S.: Zit. bei HESS, W.
Hartmann, F., U. K. Kellerhoff: Der Eiweißstoffwechsel bei fehlendem Pankreas unter Behandlung mit tierischen und pflanzlichen Fermentpräparaten. Klin. Wschr. 1955, 896–899.
Harvey: Zit. bei Cliffton, E. E.
Hawk, P. B., B. L. Oser and W. H. Summerson: Practical physiological chemistry, p. 772. Philadelphia: The Blakiston Comp. 12th Ed. 1947.
Hegglin, R.: Differentialdiagnose innerer Krankheiten. 7. Aufl. Stuttgart: Thieme-Verlag 1960.
Helsdingen, G. C. F. Van: Pancreatico-duodenectomy. S. Afr. med. J. 32, 475–477 (1958).
Henning, N., H. Schön U. W. Fahsold: Untersuchungen über die Fettresorption beim Menschen. Dtsch. Med. Wschr. 1960, 777–781.
Hernberg, C. A.: The bone structure in alloxan-induced diabetes mellitus in rats. Acta med. scand. 142, 274 (1952).
Hernberg, C. A.: Skelettveränderungen Bei Diabetes Mellitus Des Erwachsenen. Acta Med.Scand. 143, 1 (1952).
Hess, W.: Chirurgie des Pankreas. Basel: Benno Schwabe u. Co. 1950.
Hess, W.: Fragen Und Ergebnisse Der Pankreaschirurgie. Gastroenterologia (Basel) 78, 127–151 (1952).
Hilst, W., C. L. Kaufman and G. S. Wilson: Pancreatoduodenectomy for periampullary Carcinoma. Arch. Surg. (Chicago) 78, 738–744 (1959).
Honjo, J.: Especially total pancreatico-duodenectomy and the subsequent physiologic changes. Fclia endocrin. jap. 28, 55–68 (1952).
Honjo, J.: Total pancreatectomy. J. int. Coll. Surg. 25, 551–557 (1956).
Hubbard, T. B.: Carcinoma of the head of the pancreas; resection of the portal vein and porto-Caval Shunt. Ann. Surg. 147, 935–944 (1958).
Hudson, J. R.: Ocular findings in haemochromatosis. Brit. J. Ophthal. 37, 242–246 (1953).
L’huillier, A.: A case of congenital lymphosarcoma of the pancreas in a 9 days old girl. Virchows Arch. Path. Anat. 178, 507 (1904).
Jacobi, J.: Folgezustände nach totaler Pankreatektomie. Dtsch. med. J. 1955, 365–367.
Jarret, I. G.: Aust. J. exp. Biol. med. Sei. 24, 95 (1946).
Jarret, I. G., B. J. Potter and A. Packttam: Effects of pancreatectomy in the sheep. Aust. J. exp. Biol, med. Sei. 34, 133–142 (1956).
Jarrin, N.: A case of total pancreatectomy. Alex. Blain. 9iA birthday nr., p. 68–72. Detroit: Hosp. Bull. 1950.
Johnsson, S.: Retinopathy and nephropathy in diabetes, comparison of the effects of two Forms of Treatment. Diabetes 9, 1–8 (1960).
Jordan, P. H., and M. J. Grossman: Pancreatoduodenectomy for chronic relapsing pancreatitis. Metabolic effects created by total and subtotal ablations. Arch. Surg. (Chicago) 74, 871–880 (1957).
Jordan, G. L., and E. L. Shelton: Symptom of jaundice following pancreatoduodenal Resection. J. Amer. Med. Ass. 162, 196–197 (1956).
Kausch, W.: Das Karzinom der Papilla duodeni und seine radikale Entfernung. Beitr. klin. Chir. 78, 439–486 (1912).
Keiding, N. R., H. E. Root and A. Marble: Importance of control of diabetes in prevention of Vascular Complications. J. Amer. Med. Ass. 150, 964 (1952).
Kirtland, A. B.: A safe methode of pancreatic biopsy. A preliminary report. Amer. J. Surg. 82, 451–457 (1954).
Körte, H.: Die chirurgischen Krankheiten und die Verletzungen des Pankreas. Stuttgart: Enke 1898.
Kornerup, T.: Studies in diabetic retinopathy. Acta med. scand. 153, 81 (1955).
Krönlein, U.: Klinische und topographisch-anatomische Beiträge zur Chirurgie des Pankreas. Bruns’ Beitr. Klin. Chir. 14, 663–696 (1895).
Kühnlein, E.: Stoffwechselstudien nach totaler Pankreatektomie wegen Hyperinsulinismus (Beobachtungszeit 9 Monate). Yerh. dtsch. Ges. Verdau.- u. Stoffwechselkr. 1953, 174–177.
Lahey, F. H., and D. C. Mckinnon: Carcinoma of the pancreas. Surg. Clin. N. Amer. 18, 695–704 (1938).
Leger, L., Et J. Brehant: Chirurgie du pancréas. Paris: Masson et Cie 1956.
Lehner, A.: Die Chirurgie des Pankreaskarzinoms. Gastroenterologia (Basel) 78, 152–168 (1952).
Lehner, A.: Ergebnisse Der Duodenopankreatektomie. Helvet. Chir. Acta 24, 340–345 (1957).
Leites, S. M.: Über die Rolle des Lipokains (lipocaic substance) in der Pathogenese des Diabetes mellitus. Diabetes mellitus. 3. Kongr. int. Diab. Feder. Düsseldorf 1958, 740–746. Stuttgart: G. Thieme 1959.
Lieber, M. M., H. C. Stewart and H. Lund: Carcinoma of the periampullary portion of the Duodenum. Ann. Surg. 109, 219–245 (1939).
Litten, M.: Ein Fall von Pankreassarkom mit enormen Metastasen bei einem 4jährigen Knaben. Dtsch. Med. Wschr. 1888, 901.
Loeweneck, M., U. J. Jacobi: Beobachtungen beim Pankreatektomierten. Verh. dtsch. Ges. Verdau.- U. Stoffwechselkr. 1953, 177–179.
Longmire, W. P., P. H. Jordan and J. D. Briggs: Experience with resection of the pancreas in the treatment of chronic relapsing pancreatitis. Ann. Surg. 144, 681–695 (1956).
Loggan, P. B., B. Powell and L. J. Kleins Asser: Surgery of the pancreas; the results of pancreaticoduodenal resections reported in the literature. Surg. Gynec. Obstet. 93, 521–543 (1951).
Lukens, F. D. W.: Pancreatectomy in the goat. Amer. J. Physiol. 122, 729–733 (1938).
Lukens, F. D. W.: Pancreatectomy in the pig. Amer. J. Physiol. 118, 321–327 (1937).
Lukens, F. D. W.: Experimental diabetes and its relation to diabetes mellitus. Amer. J. Med. 19, 790–797 (1955).
Lundbaek, K.: Das spätdiabetische Syndrom-Angiopathia diabetica. Ergebn. inn. Med. Kinderheilk. N. F. 8, 1–75 (1957).
Lynch, R. C., and D. M. L. Rosenberg: Intraintestinal hemorrhage following total pancreatectomy for carcinoma of the pancreas. Surgery 31, 436–442 (1952).
Malcolm, J. D.: Removal of a sarcomatous tumor from the tail of the pancreas of a child 4 Years and 8 Months Old. Lancet 1902, 586.
Mallet-Guy, P.: Sur les pancréatectomies pour cancer du pancréas. Mém. Acad. Chir. 74, 35–40 (1948).
Mallet-Guy, P.: Sphincterotomy and splanchnicectomy in the treatment of chronic relapsing pancreatitis. Arch. Surg. (Chicago) 72, 366–370 (1956).
Malthe: Festschrift für Prof. Heiberg. Kristiania 1895. Zit. nach Körte, H. Marble, A., u. J. Steinke: Hämochromatose. Bericht über 42 Fälle mit Diabetes. Medizinische 1959, 19–23.
Marraffino, B.: Total pancreatectomy for adenocarcinoma of the pancreas. N. Y. St. J. Med. 50, 1124–1127 (1950).
Matthewson Jr., C.: Indications for pancreatico-duodenectomy. West. J. Surg. 60, 503–509 (1952).
Mazingarbe, A.: Papillectomie pour cancer de l’ampoule de Vater (Récidive. Pancréatectomie totale. Guérison de quatre moins). Mém. Acad. Chir. 77, 685–687 (1951).
Mazingarbe, A., J. Roussillon, Y. Geffroy Et P. Renault: Deux cas deduodéno-pancréatectomie totale. Mém. Acad. Chir. 78, 771–775 (1952).
Mcclure, R. D., and B. E. Brush: Experiences with islet cell tumors. Arch. Surg. (Chicago) 59, 507–513 (1949).
Mccullagh, E. P., R. J. Cook and E. K. Shirey: Diabetes following total pancreatectomy. Diabetes 7, 298–307 (1958).
Mccullagh, E. P., R. J. Cook and H. W. Goebert: Effects of insulin with and without tolbutamide in a pancreatectomized woman. Diabetes 8, 315–316 (1959).
Mcdermott Jr., W. Y.: A one-stage pancreatoduodenectomy with resection of the portal vein for Carcinoma of the Pancreas. Ann. Surg. 136, 1012–1018 (1952).
Mcintosh, H. W., and E. P. Carruthers: Metabolic effects of the administration of growthhormon to a pancreatectomized individual. Canad. med. Ass. J. 67, 428–431 (1952).
Mclaughlin, E. F., and J. S. C. Harris: Total pancreatectomy for recurrent calcerous pancreatitis. Ann. Surg. 186, 1024–1030 (1952).
Mentha, C.: Ostéodystrophies pancréatiques humaines et expérimentales. Schweiz. Z. allg. Path. 4, 209–300 (1941).
Mering, J. Von, U. O. Minkowski: Diabetes mellitus nach Pankreasexstirpation. Naunyn-Schmiedeberg’s Arch. Exp. Path. Pharmak. 26, 371–387 (1890).
Meythaler, F., U. E. Kühnlein: Der Pankreatektomiediabetes beim Menschen. Neuraimedizin 4, 312–315 (1956).
Meythaler, F., U. E. Kühnlein: Die totale Pankreasentfernung beim Menschen. Mit Bericht über einen bisher 20 Monate Beobachteten Fall. Ärztl. Forsch. 7, 489–503 (1953).
Millar, T. W.: The management of the carcinoma of the bile ducts, of the ampulla of Vater and Of The Pancreas. Edinb. Med. J. 1951, 1–24.
Millbourn, E.: Experiences of radical pancreatic surgery in cases of carcinoma of the head of The Pancreas or the Papilla of Vater. Acta Chir. Scand. 116, 1–11 (1958).
Miller, E. M., and O. T. Clagett: Survival five years after radical pancreatoduodenectomy for carcinoma of the head of the pancreas. Ann. Surg. 134, 1013–1017 (1951).
Miller, E. M., M. B. Dockerty, E. E. Wollaeger and J. M. Waugh: Carcinoma in the region of the papilla of Vater. A study of cases in which resection was performed. Surg. Gynec. Obstet. 92, 172–182 (1950).
Miller, E. M., and J. W. Craig: Hypoglycemic effects of l-butyl-3-p-toluene sulfonylurea given orally in human diabetic subjects. Metabolism 5, 162–164 (1956).
Minkowski, O.: Untersuchungen über den Diabetes mellitus nach Exstirpation des Pankreas. Naunyn-Schmiedeberg’s Arch. Exp. Path. Pharmak. 81, 85–189 (1893).
Mirsky, I. A.: Insulinase, Insulinase-Inhibitors and diabetes mellitus. Recent Progr. Hormone Res. 13, 429 (1956).
Mirsky, I. A., and R. H. Broh-Kahn: The inactivation of insulin by tissue extracts. Arch. Biochem. 20, 1 (1949).
Mirsky, I. A., P. Futtermann, J. Wachmann and G. Perisutti: The influence of pancreatectomy on the metabolic state of the alloxandiabetic dog. Endocrinology 49, 73–81 (1951).
Mirsky, I. A., N. Nelson, J. Grayman and M. Koremberg: Studies on normal and depancreatized domestic ducks. Amer. J. Physiol. 135, 223–229 (1941).
Montgomery, M. L., C. Entenman, G. E. Gibbs and I. L. Chaikoff: Influence of ingestion of pancreatic juice upon liver fat in depancreatized dogs maintained with insulin. Proc. Soc. exp. Biol. (N. Y.) 43, 349–351 (1940).
Moore, G. E., and B. Ure: One-stage-pancreatico-duodenectomy with resection of the superior mesenteric vein. Surgery 35, 734–742 (1954).
Moore, R. G., and J. D. Younghttsband: Carcinoma of the head of the pancreas. A review of 49 personal cases. Brit. J. Surg. 41, 562–574 (1954).
Morel, E. L., J. Janzen and J. Carter: Pancreaticoduodenal resection. Amer. J. Gastroent 21, 435–440 (1954).
Mount, L. E.: Alloxandiabetes in the piglet. Nature (Lond.) 180, 344 (1957).
Muir, E. G.: Resection for carcinoma of head of pancreas. Two 5-years survivals. Brit. J. Surg. 42, 489–490 (1955).
Nadal, J. W.: Islet cell carcinoma of the pancreas: report of a survival of eight years. Ann. Surg. 136, 13 (1952).
Nanson, E. M.: An unusual case of carcinoma of the head of the pancreas. Brit. J. Surg. 41. 439 (1954).
Nardi, G. L.: Metabolic studies following total pancreatectomy for retroperitoneal leiomyo-sarcoma. New Engl. J. Med. 247, 548–550 (1952).
Natjnyn, B.: Der Diabetes mellitus. 2. Aufl. Wien 1906.
Ogryzlo, M. A., and J. Harrison: The effect of BZ 55 on pancreatic diabetes following pancreatectomy. Canad. med. Ass. J. 74, 977–978 (1956).
Olsson, O.: Total pancreasexstirpation. Nord. Med. 43, 988–991 (1950).
Orr, T. G.: Resection of duodenum and head of pancreas for carcinoma of the ampulla. Surg. Gynec. Obstet. 73, 240–243 (1941).
Oughterson: Zit. bei Cliffton, E. E.
Parsons, W. B.: Carcinoma of the pancreas and carcinoma of the ampulla of Yater: an evaluation. Bull. N. Y. Acad. Med. 27, 339 (1951).
Patel, J., M. Arsac Et M. Redox: L’expérience qu’on a, jusqu’ici, de la duodéno–pancréat– ectomie totale. Presse méd. 1951, 1267–1270.
Popper, H. L., and H. Necheles: Relation of pancreatic secretion to fatty acids in liver. Proc. Soc. exp. Biol. (N. Y.) 51, 63–65 (1942).
Porter, M. R.: Carcinoma of the pancreatico-duodenal area. Operability and choice of procedure. Ann. Surg. 148, 711–724 (1958).
Pratt, J. H., and J. S. Welch: Carcinoma of the head of the pancreas, longterm survival, report of a case. Arch. Surg. (Chicago) 72, 500–501 (1956).
Priestley, J. T., M. W. Comfort and J. Radcliffe: Total pancreatectomy for hyperinsulinism due to islet-cell adenoma; survival and cure at 16 months after operation; presentation of metabolic studies. Ann. Surg. 119, 211–221 (1944).
Priestley, J. T., and R. G. Spragtje : Total pancreatectomy for hyperinsulinism due to islet–cell adenoma.
Follow-up report five and one-half years after operation including metabolic studies. Ann. Surg. 130, 211–217 (1949).
Purnell, R., Y. Arai, E. Pratt, C. Hlad and H. Elrick: Some observations on the mode of action of orinase. Metabolism 5, 779–787 (1956).
Ramström: Zit. bei Olsson, O.
Ransom, H. K.: Carcinoma of the body and tail of the pancreas. Arch. Surg. (Chicago) 30, 584–606 (1935).
Redon, H.: Un sujet des duodéno-pancréatectomies. Mém. Acad. Chir. 77, 214–216 (1951).
Rhoads, J. E., H. A. Zintel and J. Helwig Jr.: Results of operation of the Whipple type in pancreaticoduodenal carcinoma. Ann. Surg. 146, 661–668 (1957).
Ricketts, H. T., A. Brunschwig and K. Knowlton: Effects of total pancreatectomy in a patient with diabetes. Amer. J. Med. 1, 229–245 (1946).
Ricketts, H. T., A. Brunschwig and K. Knowlton: Diabetes in total depancreatized man. Proc. Soc. exp. Biol. (N. Y.) 58, 254–255 (1945).
Ripstein, C. B., and W. Ostrow: Gastrointestinal function following radical pancreato–duodenectomy. Rev. Gastroenterol. 18, 272–282 (1951).
Rives, J., S. Romano and F. Sandifer: Carcinoma of the pancreas. Surg. Gynec. Obstet. 65, 164 (1937).
Rivorola, J. E., R. Maggi U. A. Toce: Verschlußikterus bei einem 1jährigen Mädchen; Tumor des Pankreaskopfes; einzeitige Gastroduodenalpankreatektomie. Bol. Soc. Cir. Buenos Aires 78, 442–458 (1954).
Rob, C., and R. Smith: Diagnosis and results of treatment of cancer of the pancreas and Ampulla Of Vater. Brit. Med. J. 1954, 330.
Rockey, E. W.: Total pancreatectomy for carcinoma. Ann. Surg. 118, 603–611 (1943).
Rodríguez-Candela, J. L.: The hyperglycemic-glycogenolytic factor produced by the pancreas. J. clin. Endoer. 12, 245 (1952).
Root, G. T.: Diskuss. Bemerkung. Arch. Surg. (Chicago) 78, 742 (1959).
Ross, D. E.: Cancer of the pancreas with two case reports of 5-years-survivals. Amer. J. Surg. 93, 990–994 (1957).
Ross, D. E.: Cancer Of Pancreas: a plea for total pancreatectomy. Amer. J. Surg. 87, 20–33 (1954).
Routier: Rev. de Chirurgie 12, 1892. Zit. nach Körte, H.
Rudler, J. C., Et P. Monod-Broca: Duodéno-pancréatectomie totale pour cancer du 2 Duodénum. Mém. Acad. Chir. 77, 195–198 (1951).
Rudström, P.: Kirurgish behandling av pancreas cancer. Nord. Med. 57, 69 (1957).
Ruggi: G. ital. Sei. Med. 12 (1890). Zit. nach Körte, H.
Sauer, H., J. G. Rausch-Stroomann U. E. Hoffmann-Conrads: Über die Bedeutung der Nebennierenrindenfunktion bei der diabetischen Retinopathie und Glomerulosklerose. Endokrinologie 36, 237–247 (1958).
Sauvé, L.: Des pancréatectomies et spécialement de la pancréatectomie céphalique. Rev. Chir. (Paris) 87, 113 U. 335 (1908).
Saviano, M. E P. De Franciscis: SOC. Ital. biol. Sper. 22, 1245 (1946).
Schnedorf, J. G., and T. G. ORR: Fifty-two proven cases of carcinoma of the pancreas and ampulla of Vater: with special reference to fatty infiltration of the liver. Ann. Surg. 114, 603–611 (1941).
Schupbach, A.: Endokrines System und Skelett. Helv. med. Acta 15, 537 (1948).
Scow, R. O.: “Total” pancreatectomy in the rat: operation, effects and postoperative care. Endocrinology 60, 359–367 (1957).
Seltzer, H. S., and W. L. Smith: Plasma insulin activity after glucose. Diabetes 8, 417–424 (1959b).
Sendler, P.: Zur Pathologie und Chirurgie des Pankreas. Dtsch. Z. Chir. 44, 329 (1897).
Senff, A.: Neue, vereinfachte Resektionsmethode beim Pankreaskopf-Ca. Arch. klin. Chir. 264, 446–447 (1950). Shay: Zit. bei DITURI.
Siler, V. E., and M. M. Zinninger: Surgical treatment of carcinoma of the ampulla of Vater and The Extrahepatic Bile Ducts. Arch. Surg. (Chicago) 56, 199–223 (1948).
Silver, G. B., U. R. K. Lubliner: Zit. bei Hess, W.
Silverstone, M.: Pancreaticoduodenectomy and pancreaticogastrostomy. A five year-survival, Whithin Notes On The Metabolism. Brit. J. Surg. 44, 299–302 (1956).
Skillman, Th. G., F. A. Kruger and G. J. Hamwi: Metabolic and endocrine studies with Phenethylbiguanide (Dbi). Diabetes 8, 274–278 (1959).
Smith, J. O., and G. Brown: Pancreatico-duodenal resection for carcinoma. Aust. N. Z. J. Surg. 22, 1–7 (1952).
Smith, R.: Long-term-survival after pancreatectomy for cancer. Brit. J. Surg. 44, 294–296 (1956).
Späth, F., U. W. Köle: Über den derzeitigen Stand der Chirurgie des Pankreaskopfkarzinoms. Langenbecks Arch. Klin. Chir. 278, 272–289 (1954).
Spjut, H. J., and A. J. Ramos : An evaluation of biopsy-frozen section of the ampullary region
And Pancreas: a report of 68 consecutive patients. Ann. Surg. 146, 923–930 (1957).
Sprague, R., and A. C. Ivy: Studies in avian carbohydrate metabolism. Amer. J. Physiol. 115, 389–394 (1936).
Sprague, R., and A. C. Ivy: Diabetes Associated With Chronic Relapsing Pancreatitis. Proc. Mayo Clin. 22,553–558 (1947). Stawell: Zit. nach Duncan U. Mitarb.
Stritzko, O.: Zur Radikaloperation des Pankreaskopfcarcinoms. Wien. med. Wschr. 1958, 986–990.
Tendler, M. J., and G. R. Livermore Jr.: Role of biopsy and radical operation in the management of carcinoma of the head of the pancreas. Ann. Surg. 150, 290–295 (1959).
Terrier: Ann. Univ. med. Sci. 1891, 56. Zit. nach Körte, H. Thompson: Zit. bei Cattell and Pyrtek.
Thompson, J. A., J. R. Derrick and J. M. Howard: Relapsing pancreatitis in alcoholic and Nonalcoholic Patients. Surgery 42, 841–845 (1957).
Thorogod, E., and B. Zimmermann: The effects of pancreatectomy on glucosuria and ketosis In Dogs Made Diabetic By Alloxan. Endocrinology 37, 191–200 (1945).
Tidwell, H. C., C. Dunkelberg, W. A. Wood and W. W. Burr: Measurement of the rate of fat absorption. J. biol. Chem. 220, 733–740 (1956).
Tidwell, H. C., and J. M. Johnston: Methods for measuring fat absorption. Proc. Soc. exp. Biol. (N. Y.) 94, 150 (1957).
Trendelenburg, W.: Zit. bei Franke, F.
Trendelenburg, W.: Dtsch. Z. Chir. 24, 326 (1886). Zit. nach Körte, H..
Trimble, J. R., J. Ridgeway, J. W. Parsons and C. P. Sherman: A one stage operation for the cure of carcinoma of the ampulla of Vater and of the head of the pancreas. Surg. Gynec. Obstet. 78, 711–722 (1941).
Tscherepina, M. J.: Ein Fall von primärem Pankreassarkom. Zbl. allg. Path. path. Anat. 50, 50 (1930).
Vossschulte, K.: Über totale und partielle Pankreasresektion wegen perniciösem Hyper-insulinismus. Verh. dtsch. Ges. Verdau.-u. Stoffwechselkr. 1953, 193–195.
Vossschulte, K., U. W. H. Becker: Über die Problematik der chirurgischen Maßnahmen bei der Hypoglykämie durch Tumor oder sogenannte Hyperplasie des Inselapparates. Dtsch. med. Wschr. 1958, 185–190.
Wallau, F.: Verhältnis des Krebses der Bauchspeicheldrüse zu seinen Absiedlungen. Virchows Arch. path. Anat. 283, 321–324 (1932).
Walters, W., and W. H. Cleveland: Surgical lesions of the pancreas. Arch. Surg. (Chicago) 42, 819 (1941).
Waugh, J. M.: Radical resections of head of pancreas and total pancreatectomy. J. Amer. med. Ass. 137, 141–144 (1948).
Waugh, J. M., and O. T. Clagett: Resection of the duodenum and head of the pancreas for carcinoma. Surgery 20, 224–232 (1946).
Waugh, J. M., C. F. Dixon, 0. T. Clagett, J. L. Bollman, R. G. Sprague and M. W. Comfort: Total pancreatectomy: a symposium presenting four successful cases and a report on metabolic observations. Proc. Mayo Clin. 21, 25–48 (1946).
Waugh, J. M., and R. G. Giberson: Radical resections of the head of the pancreas for malignant lesions. Analysis of 85 cases. Surg. Clin. N. Amer. 37, 965–979 (1957).
Wells, C., J. A. Shepherd and N. Gibbon: Pancreaticogastrostomy. Lancet 1952, 588.
Wenzl, M.: Über den derzeitigen Stand der Chirurgie des Pankreaskopfkarzinoms. Krebsarzt 4, 129–135 (1949).
Westerborn: Zit. bei Olsson, O.
Wetzel, U., U. H. G. Meyer-Wegener: Zur Klinik des Pankreaskopfkarzinoms. Ärztl. Wschr. 1954, 721–724.
Whitfield, A. G. W., A. Gourevitch and G. Thomas: Metabolie effects of total pancreatectomy in man. Lancet 1952, 180–183.
Whipple, A. O.: Surgical treatment of carcinoma of the ampullary region and head of pancreas. Amer. J. Surg. 40, 260–263 (1938).
Whipple, A. O.: Radical surgery for certain cases of pancreatic fibrosis associated with calcereous deposits. Ann. Surg. 124, 991–1008 (1946).
Whipple, A. O., W. B. Parsons and C. R. Mullins: Treatment of carcinoma of the ampulla of Vater. Ann. Surg. 102, 763–779 (1935).
Wollaeger, E. E., M. W. Comfort, 0. T. Clagett and A. E. Osterberg: Efficiency of gastrointestinal tract after resection of head of pancreas. J. Amer. Med. Ass. 137, 838–848 (1948).
Wrenshall, G. A., A. Bogoch and R. C. Ritchie: Extractable insulin of pancreas, correlation with pathological and clinical findings in diabetic and nondiabetic cases. Diabetes 1, 87 (1952).
Wrenshall, G. A., and J. D. Hamilton: Sex differences in the amount of insulin extractable from diabetic human pancreas. Ann. N. Y. Acad. Sei. 71, 154–163 (1957).
Yoshioka, H., and T. Wakabayashi: Therapeutic neurotomy of head of pancreas for relief of pain due to chronic pancreatitis. Arch. Surg. (Chicago) 76, 546–554 (1958).
Ziegler, H. R.: Excision of the head of the pancreas for carcinoma with studies of its blood supply. Surg. Gynec. Obstet. 74, 137–145 (1942).
Zollinger, R. N.: Late Postoperative Problems Following Radical Surgery of the Stomach and Pancreas. Postgrad. Med. 23, 297–304 (1958).
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1961 Springer-Verlag OHG. Berlin · Göttingen · Heidelberg
About this paper
Cite this paper
Creutzfeldt, W., Kern, E., Kümmerle, F., Schumacher, J. (1961). Die radikale Entfernung der Bauchspeicheldrüse beim Menschen—Indikationen, Ergebnisse, Folgeerscheinungen. In: Heilmeyer, L., Schoen, R., De Rudder, B. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde. Ergebnisse der Inneren Medizin und Kinderheilkunde , vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-94808-4_3
Download citation
DOI: https://doi.org/10.1007/978-3-642-94808-4_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-94809-1
Online ISBN: 978-3-642-94808-4
eBook Packages: Springer Book Archive