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Protein metabolism of bacteria

  • Kenneth McQuillen
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Part of the Handbuch der Pflanzenphysiologie / Encyclopedia of Plant Physiology book series (532, volume 8)

Abstract

Bacteria are much the same as other organisms so far as proteins are concerned — they contain various kinds including enzymes and can synthesise and degrade proteins. They have, however, certain attributes which make them particularly useful in the study of protein metabolism. Most bacteria grow relatively rapidly — mean generation times of about 30 minutes are common and imply a fourfold increase in protein each hour. Often their nutritional requirements are simple and defined and since bacteria are easy to grow, harvest and fractionate, much isotopic tracer work has been done with them. The study of “biochemical mutants” has also led to a great deal of information notably about synthetic mechanisms in amino acid metabolism. A further, much exploited property is their ability to synthesise adaptive enzymes under the stimulus of an appropriate inducing agent (see symposium edited by Gale and Davies). Recent work on bacteriophage formation and on protein synthesis in sub-cellular bacterial preparations has raised hopes that before long we shall know much more about the way in which living organisms can, from some twenty amino acids, produce a large number (probably hundreds per cell) of uniquely specific proteins. Because of the similarity in the basic patterns of all living organisms it is justifiable to anticipate close parallels in the properties of proteins and mechanisms of protein synthesis.

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© Springer-Verlag oHG. Berlin · Göttingen · Heidelberg 1958

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  • Kenneth McQuillen

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