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Therapie der Schilddrüse mit Radiojod

  • Conference paper
Ergebnisse der Inneren Medizin und Kinderheilkunde

Part of the book series: Ergebnisse der Inneren Medizin und Kinderheilkunde ((KINDERHEILK. NF,volume 8))

Zusammenfassung

Die Therapie der Schilddrüse mit Radiojod ist eine strahlentherapeutische Methode, welche unter Anwendung der Atomkernenergie abnorme Funktionszustände beheben und normale oder pathologische Strukturen zerstören, zurückdrängen oder im Wachstum hemmen soll. Die im Atomkern eingeschlossene Energie wird beim radioaktiven Zerfall unter Aussendung energiereicher Korpuskular- und elektromagnetischer Wellenstrahlen frei. Die emittierten Strahlen sind befähigt, die Atome und Moleküle der Materie zu ionisieren und im Organismus mannigfache biologische Wirkungen hervorzurufen. Bei gezielter Anwendung und richtiger Dosierung können sie erstaunliche Heilwirkungen, bei unsachgemäßer Handhabung schwerste irreversible Schäden im bestrahlten Organismus hervorrufen. Die gezielte, allein auf den Krankheitsherd beschränkte Auslösung dieser destruktiven Wirkungen bildet die unerläßliche Voraussetzung für eine therapeutische Anwendung der energiereichen Strahlen. Beim Radio jod wird diese Vorbedingung in nahezu idealer Weise auf dem Stoffwechselweg erfüllt. Die Durchführung einer rationellen Therapie, die sich auf dem wissenschaftlichen Verständnis und der ärztlich begründeten Anwendung der ionisierenden Energie aufbaut, setzt nicht nur gesicherte Kenntnisse über die kernphysikalischen und strahlenbiologischen Grundlagen, sondern auch über die physiologischen und pathologischen Gesetzmäßigkeiten des Jodstoffwechsels sowie klinische Erfahrungen in der Erkennung und Behandlung der Schilddrüsenkrankheiten voraus.

Aus der Medizinischen Universitätsklinik Freiburg i. Br. (Direktor: Prof. Dr. Dr. h. c. L. Heilmeyer).

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Literatur

  • Abelin, I., U. G. Perotti: Über die Speicherung des Broms durch die Thyreoidea. Schweiz, med. Wschr. 1952, 1186.

    Google Scholar 

  • Ackermann, P. G., and K. Iversen: Radio-iodine excretion in the aged. J. of Gerontol. 8, 458 (1953).

    CAS  Google Scholar 

  • Albert, A.: Effects of altered thyroid function upon the metabolism of endogenously labeled hormone. J. Clin. Endocrin. 13, 880 (1953).

    Google Scholar 

  • Albert, A. and N. Lorenz: The effect of hypophysectomy on the intrathvroidal metabolism of I131. Proc. Soc. Exper. Biol. a. Med. 77, 204 (1951).

    CAS  Google Scholar 

  • Albright, E. C., F. C. Larson and W. P. Deiss: Thyroxine binding capacity of serum alpha globulin in hypothyroid, euthyroid, and hyperthyroid subjects. J. Clin. Invest. 34, 44 (1955).

    CAS  PubMed  Google Scholar 

  • Allen, M. S., H. H. Dunham, Ch. E. Montgomery and E. T. Siler: The treatment of hyperthyroidism with radioactive iodine I131. J. Kansas Med. Soc. 54, 120 (1953).

    CAS  Google Scholar 

  • Allen, H. C., Jr., and W. E. Goodwin: The scintillation counter as an instrument for in vivo determination of thyroid weight. Radiology 58, 68 (1952).

    CAS  PubMed  Google Scholar 

  • Allen, H. C., Jr., R. L. Libby and B. Cassen: The scintillation counter in clinical studies of human thyroid physiology using I131. J. Clin. Endocrin. 11, 492 (1951).

    Google Scholar 

  • Anderson, B. G.: Treatment of recurrent hyperthyroidism with radioactive iodine. Metabolism (N. Y.) 3, 297 (1954).

    CAS  Google Scholar 

  • Andrews, G. A.: Pathologic changes in normal human thyroid tissue following large doses of I131. Amer. J. Med. (N. Y.) 16, 372 (1954).

    CAS  Google Scholar 

  • Ansell, G., and H. Miller: Influence of iodine on the release of thyroid hormone in thyrotoxicosis. Lancet 1952 II, 5–10.

    Google Scholar 

  • Arnott, D. G., E. Wt. Emery, R. Fraser and Q. J. G. Hobson: Urinary excretion of radioactive iodine as a diagnostic test in thyroid disease. Lancet 1949 II, 460.

    Google Scholar 

  • Asper, S. P., H. A. Selenkow and C. A. Plamondon: A comparison of the metabolic activities of 3:5:3’-1-triiodothyronine and 1-thyroxine in myxedema. Bull. Johns Hopkins Hosp. 93, 164 (1953).

    CAS  PubMed  Google Scholar 

  • Balint, J. A., R. Fräser and M. G. W. Hanno: Radio-iodine measurements of thyroid function during and after P. A. S. treatment of tuberculosis. Brit. Med. J. 1954, 1234.

    Google Scholar 

  • Balls, K. F., R. H. Chamberlain, E. Rose, R. O. Gorson and H. C. Blount: The treatment of thyrotoxicosis with radioiodine. Radiology 64, 858 (1955).

    CAS  PubMed  Google Scholar 

  • Balme, H. W.: Metastatic carcinoma of the thyroid successfully treated with thyroxine. Lancet 1954 I, 812–813.

    Google Scholar 

  • Bansi, H. W.: Thyreotoxikosen und antithyreoidale Substanzen. Stuttgart: Georg Thieme 1951.

    Google Scholar 

  • Bansi, H. W.: Jodstoffwechsel, Schilddrüse und Hypophysen vor der läppen. Klin. Wschr. 1951, 33.

    Google Scholar 

  • Bansi, H. W.: “Jod” in Künstliche Radioaktive Isotope in Physiologie, Diagnostik und Therapie. Berlin-Göttingen-Heidelberg: Springer-Verlag 1953.

    Google Scholar 

  • Bansi, H. W.: Krankheiten der Schilddrüse. Im Handbuch der inneren Medizin, 4. Aufl., Bd. VII, 1. Teil. Berlin-Göttingen-Heidelberg: Springer-Verlag 1955.

    Google Scholar 

  • Barrett, T. F., H. Peck, F. K. Bauer, R. L. Libby and S. R. Jarrett: Evaluation of a thyroid panel. Practical application of scintiLations counter in diagnosis of diseases of the thyroid. J. Amer. Med. Assoc. 152, 1414 (1953).

    CAS  Google Scholar 

  • Bartels, E. C.: Postthyroidectomy myxedema after properative use of antithyroid drugs. J. Clin. Endocrin. 13, 95 (1953).

    CAS  Google Scholar 

  • Bauer, F. K.: I131 uptake in treated hyperthyroidism. Amer. J. Med. Sci. 223, 495 (1952).

    CAS  PubMed  Google Scholar 

  • Bauer, F. K., W. E. Goodwin, R. L. Libby U. B. Cassen: Visual delineation of thyroid glands in vivo. J. Labor, a. Clin. Med. 39, 153 (1952).

    CAS  Google Scholar 

  • Bauer, F. K., W. E. Goodwin, R. L. Libby U. B. Cassen: The diagnosis of morphologic abnormalities of the human thyroid gland by means of I131. Radiology 61, 935 (1953).

    CAS  PubMed  Google Scholar 

  • Baumann, E. J.: Über das normale Vorkommen des Jods im Tierkörper. III. Der Jodgehalt der Schilddrüsen von Menschen und Tieren. Z. physiol. Chem. 22, 1 (1896).

    CAS  Google Scholar 

  • Baumeister, C. F.: Radioiodine tracer and biopsy in the diagnosis and treatment of hyper-thyroidism. Arch. Surg. 67, 80 (1953).

    CAS  Google Scholar 

  • Becker, D. V., J. E. Rall, W. Peacock and R. W. Rawson: The effect of a thyrotrophs hormone preparation on the metabolism of radioiodine in euthyroid, hyperthyroid and acromegalic individuals. J. Clin. Invest. 32, 149 (1953).

    CAS  PubMed  Google Scholar 

  • Beierwaltes, W. H.: Indications and contraindications for treatment of thyroid cancer with radioactive iodine. Ann. Int. Med. 37, 23 (1952).

    CAS  PubMed  Google Scholar 

  • Berkman, A. T.: Progressive exophthalmos following thyroidectomy cured by irradiation of the cerebral centers. Radiology 62, 406 (1954).

    CAS  PubMed  Google Scholar 

  • Berkson, J., F. R. Keating Jr., M. H. Power and W. M. Mcconahey: Determination of renal clearance of radioiodine. J. Appl. Physiol. 2, 522 (1950).

    CAS  PubMed  Google Scholar 

  • Bernert, T., R. Seyss U. E. Witt: Messungen mit Radiojod in der Aerosoltherapie. Med. Klin. 1951, 1362.

    Google Scholar 

  • Berson, S. A., and R. S. Yalow: The effect of cortisone on the iodine accumulation function of the thyroid gland in euthyroid subjects. J. Clin. Endocrin. 12, 407 (1952).

    CAS  Google Scholar 

  • Berson, S. A., J. Sorrentino and B. Roswit: Determination of thyroidal plasma iodide clearance as a routine diagnostic test of thyroid function. Bull. New York Acad. Med. 27, 395 (1951).

    CAS  Google Scholar 

  • Berson, S. A., J. Sorrentino and B. Roswit: The determination of thyroidal and renal plasma I131 clearance rates as a routine diagnostic test of thyroid dysfunction. J. Clin. Invest. 31, 141 (1952).

    CAS  PubMed  Google Scholar 

  • Bertelsen, A., E. Christensen, E. Bruun and P. Becker-Christensen: Mortality, operative complications and recurrence frequency in the surgical treatment of thyrotoxicosis. Acta chir. scand. (Stockh.) 96, 133 (1947), Suppl.

    Google Scholar 

  • Beutel, A.: Der Blutcholesterinspiegel als Indikator der strahlentherapeutischen Beeinflussung der Hyperthyreosen. Strahlenther. 69, 400 (1951).

    Google Scholar 

  • Billion, H.: Radiojod zur Schilddrüsenbehandlung. Ärztl. Wschr. 1950, 689.

    Google Scholar 

  • Billion, H.: Fortschritte in der Radiojoddiagnostik und-therapie. Strahlenther. 47, 78 (1955).

    Google Scholar 

  • Billion, H., U. P. Kühne: Der Wert verschiedener Radiojodtestverfahren für die Differentialdiagnostik von Schilddrüsenfunktionsstörungen. (Mit einem Beitrag zur “aktiven Hyperplasie”.) Z. klin. Med. 152, 411 (1954).

    CAS  Google Scholar 

  • Billion, H., K. Oeff U. F. Klauer: Ergebnisse mit dem Radiojod-Test der Schilddrüse. Ärztl. Wschr. 1951, 306.

    Google Scholar 

  • Birkhill, F. R., K. E. Corrigan and H. S. Hayden: The metabolism of radioactive iodine (I131) in patients with cardiac disease. Amer. J. Roentgenol. 67, 42 (1952).

    CAS  PubMed  Google Scholar 

  • Black, B. M.: Surgical treatment of carcinoma of the thyroid gland. J. Clin. Endocrin. 9, 1422 (1949).

    CAS  Google Scholar 

  • Black, B. M., L. B. Woolner and Ch. M. Blackburn: The uptake of radioactive iodine by carcinoma of the thyroid gland: A study of 128 cases. J. Clin. Endocrin. 13, 1378 (1953).

    CAS  Google Scholar 

  • Blackburn, Ch. M., and M. H. Power: Diagnostic accuracy of serum protein bound iodine determination in thyroid disease. J. Clin. Endocrin. 15, 1379 (1955).

    CAS  Google Scholar 

  • Blomfield, G. W., J. C. Jones, A. G. Macgregor, H. Miller and E. J. Wayne: Treatment of thyrotoxicosis with radioactive iodine. Brit. Med. J. 19511, 373.

    Google Scholar 

  • Blumgart, H. L., and D. D. Berlin: Therapeutic effect of ablative of normal thyroid on congestive heart failure and angina pectoris. Arch. Int. Med. 51, 866 (1933).

    Google Scholar 

  • Blumgart, H. L., D. Davis, J. E. F. Riseman and A. A. Weinstein: Treatment of angina pectoris and congestive heart failure by total ablation of the thyroid in patients without thyro-toxicosis. Ann. Int. Med. 7, 1449 (1933/34).

    Google Scholar 

  • Blumgart, H. L., and A. St. Freedberg: The heart and the thyroid: With particular reference to I131 treatment of heart disease. Circulation (New York) 6, 222 (1952).

    CAS  Google Scholar 

  • Blumgart, H. L., and R. Buka: Treatment of euthyroid cardiac patients by producing myxedema with radioactive iodine. Proc. Soc. Exper. Biol. a. Med. 67, 190 (1948).

    CAS  Google Scholar 

  • Blumgart, H. L., and G. S. Kurland: Hypothyroidism produced by radioactive iodine (I131) in the treatment of euthyroid patients with angina pectoris and congestive heart failure. Circulation (New York) 1, 1105 (1950).

    CAS  Google Scholar 

  • Blumgart, H. L., and G. S. Kurland: Treatment of incapacitated euthyroid cardiac patients by producing hypo-thyroidism with radioactive iodine. New England J. Med. 245, 83 (1951).

    CAS  Google Scholar 

  • Blumgart, H. L., and G. S. Kurland: Treatment of incapacitated euthyreoid cardiac patients with radioactive iodine. J. Amer. Med. Assoc. 157, 1 (1955).

    CAS  Google Scholar 

  • Blumgart, H. L., S. A. Levine and D. D. Berlin: Congestive heart failure and angina pectoris: The therapeutic effect of thyroidectomy on patients without clinical or pathologic evidence of thyroid toxicity. Arch. Int. Med. 51, 866 (1933).

    Google Scholar 

  • Boatman, J. B., and C. Moses: Role of erythrocyte in blood iodine transport using radio-iodine I131. Amer. J. Physiol. 164, 783 (1951).

    CAS  PubMed  Google Scholar 

  • Bondy, P. K., and M. A. Hagewood: Effect of stress and cortisone on plasma protein-bound iodine and thyroxine metabolism in rats. Proc. Soc. Exper. Biol. a. Med. 81, 328 (1952).

    CAS  Google Scholar 

  • Bondy, P. K., and M. A. Hagewood: Effect of stress and cortisone on plasma protein-bound iodine and thyroxine metabolism in rats. Proc. Soc. Exper. Biol. a. Med. 81, 328 (1952).

    CAS  Google Scholar 

  • Botkin, A. L., and H. Jensen: The effect of epinephrine and thyrotropin on thyroid function in rats. Endocrinology (Springfield, 111.) 50, 68 (1952).

    CAS  Google Scholar 

  • Botkin, A. L., and H. Jensen: The effect of epinephrine and thyrotropin on thyroid function in rats. Endocrinology (Springfield, 111.) 50, 68 (1952).

    CAS  Google Scholar 

  • Brands, K., U. C. Montag: Die Beeinflussung der radioaktiven Jodspeicherung der Schilddrüse durch Keimdrüsenhormone. Arch. Geschwulstforsch. 6, 11 (1953).

    CAS  PubMed  Google Scholar 

  • Braun-Wotke, J.: Lungentuberkulose und Strumektomie. Wien. klin. Wschr. 1952, 836.

    Google Scholar 

  • Brockman, D. D., and R. M. Whitman: Post-thyrodectomy psychoses. J. Nerv. Ment. Dis. 116, 340 (1952).

    CAS  PubMed  Google Scholar 

  • Brügel, H.: Die Behandlung der Thyreotoxikose mit radioaktivem Jod. Dtsch. med. Wschr. 1956, 135.

    Google Scholar 

  • Burrows, B. A., T. Peters and J. F. Ross: The tissue utilization of endogenous: Thyroid hormone in human subjects. J. Clin. Invest. 33, 921 (1954).

    Google Scholar 

  • Burrows, B. A., J. F. Ross, E. S. Dell, D. E. Graham and D. F. Hammack: The thyroidal uptake of stable iodine compared with the serum concentration of protein-bound iodine in normal subjects and in patients with thyroid disease. J. Clin. Endocrin. 13, 1358 (1953).

    CAS  Google Scholar 

  • Cassen, B., L. Curtis, C. Reed and R. L. Libby: Instrumentation for I131 use in medical studies. Nucleonics 9, 46 (1951).

    Google Scholar 

  • Catz, B., I. El Rawi and E. Geiger: Increased I131 collection by the thyroid of the rat in acute starvation. Amer. J. Physiol. 172, 291 (1953).

    CAS  PubMed  Google Scholar 

  • Chaikoff, I. L., and A. Taurog: Studies on the formation of organically bound iodine compounds in the thyroid gland and their appearance in plasma as shown by the use of radioactive iodine. Ann. N. Y. Acad Sci. 50, 379 (1949).

    Google Scholar 

  • Chaikoff, I. L., and W. O. Reinhardt: The metabolic significance of protein-bound iodine of plasma: A study of its concentration under various conditions and of its rate of formation as measured with radioactive iodine. Endocrinology (Springfield, 111.) 40, 47 (1947).

    CAS  Google Scholar 

  • Chapman, E. M.: Treatment of Graves’ disease with radioactive iodine. West. J. Surg. 56, 47 (1948).

    CAS  PubMed  Google Scholar 

  • Chapman, E. M.: Radioactive iodine in therapy of cancer of the thyroid. 2nd. National Cancer Conference Cincinnati, Ohio, March 3–5, 1952.

    Google Scholar 

  • Chapman, E. M., G. W. Corner, D. Robinson and R. D. Evans: The collection of radioactive iodine by the human fetal thyroid. J. Clin. Endocrin. 8, 717 (1948).

    CAS  Google Scholar 

  • Chapman, E. M., and R. D. Evans: The treatment of hyperthyroidism with radioactive iodine. J. Amer. Med. Assoc. 181, 86 (1946).

    Google Scholar 

  • Chapman, E. M., and R. D. Evans: Treatment of toxic goiters with radioactive iodine. Med. Clin. N. Amer. 33. 1211 (1949).

    CAS  PubMed  Google Scholar 

  • Chapman, F. Maloof, J. Maisterrena and J. Martin: Ten years’ experience with radioactive iodide. J. Clin. Endocrin. 14, 45 (1954).

    CAS  Google Scholar 

  • Chapman, F. Maloof, B. Skanse and R. D. Evans: Treatment of hyperthyroidism with radioactive iodine. Radiology 51, 558 (1948).

    CAS  PubMed  Google Scholar 

  • Chester, J., P. Lerch Et A. Vannotti: A propos du traitement par l’iode radioactif du cancer et des métastases d’origine thyroidienne. Schweiz. med. Wschr. 1950, 1377.

    Google Scholar 

  • Chevalley, J., T. H. Mcgavack, S. Kenigsberg and S. Pearson: A four-year study of the treatment of hyperthyroidism with Methimazole. J. Clin. Endocrin. 14, 948 (1954).

    CAS  Google Scholar 

  • Childs, D. S. Jr., F. R. Keating, J. E. Rall, M. M. D. Williams and M. H. Power: The effect of varying quantities of inorganic idodide (carrier) on the urinary excretion and thyroidal accumulation of radioiodine in exophthalmic goiter. J. Clin. Invest. 29, 726 (1950).

    CAS  PubMed  Google Scholar 

  • Clark, D. E., J. H. Rule, O. H. Trippel and D. A. Cofrin: Five year experience with radioactive iodine in treatment of hyperthyroidism. J. Amer. Med. Assoc. 150, 1269 (1952).

    CAS  Google Scholar 

  • Clark, D. E., O. H. Trippel and G. E. Sheline: Diagnostic and therapeutic use of radioactive iodine. Arch. Int. Med. 87, 17 (1951).

    CAS  Google Scholar 

  • Coliez, R., M. Tubiana, J. Dutreix Et J. Guelfi: Résultats du traitement de 43 cas de cancer du corps thyroide par l’iode radio-actif. J. de Radiol. 34, 305 (1953).

    CAS  Google Scholar 

  • Cook, J. R., R. W. Jones and E. P. Mccullagh: Treatment of toxic adenomatous goiter by large doses of radioactive iodine. J. Clin. Endocrin. 15, 1512 (1955).

    CAS  Google Scholar 

  • Corbett, B. D., and A. J. Honour: Design of directional counters for clinical use. Nucleonics 9, 43 (1951).

    Google Scholar 

  • Crile, G.: Treatment of tumors of the thyroid with divided doses with radioactive iodine. Amer. J. Roentgenol. 65, 415 (1951).

    Google Scholar 

  • Crile, G.: The danger of surgical dissemination of papillary carcinoma of the thyroid. Surg. etc. 102, 161 (1956).

    Google Scholar 

  • Crile, G., and W. S. Dempsey: Indications for removal of nontoxic nodular goiters. J. Amer. Med. Assoc. 139, 1247 (1948).

    Google Scholar 

  • Crile, G., and W. S. Dempsey: and E. P. MCCULLAGH: The treatment of hyperthyroidism. An evaluation of thyroid-ectomy, of prolonged administration of propylthiouracyl, and of radioactive iodine. Ann. Surg. 134, 18 (1951).

    PubMed  Google Scholar 

  • Crile, G., and W. S. Dempsey: and O. GLASSER: Experience with radioactive iodine in the treatment of hyper-thyroidism. Cleveland Clin. Quart. 16, 1 (1949).

    PubMed  Google Scholar 

  • Dailey, M. E., S. Lindsay and E. R. Miller: Histologic lesions in thyroid glands of patients receiving I131 for hyperthyroidism. J. Clin. Endocrin. a. Metabol. 13, 1513 (1953).

    CAS  Google Scholar 

  • Dailey, M. E., M. H. Soley and S. Lindsay: Carcinoma of thyroid gland: A clinical and pathological study. Amer. J. Med. 9, 194 (1950).

    CAS  PubMed  Google Scholar 

  • Dargent, H., and P. Guinet: The early stages of thyroid carcinoma. Brit. Med. J. 1952, No. 4794, 1122.

    Google Scholar 

  • Dargent, M., J. Papillon Et P. Guinet: La radiosensibilisation des épithéliomas thyroidiens par l’aminothiazol (Étude critique). J. de Radiol. 30, 15 (1949).

    CAS  Google Scholar 

  • Deiss, W. P., E. C. Albright and F. C. Larson: A study of the nature of the circulating thyroid hormone in euthyroid and hyperthyroid subjects bv use of paper electrophoresis. J. Clin. Invest. 31, 1000 (1952).

    CAS  PubMed  Google Scholar 

  • Deiss, W. P., E. C. Albright and F. C. Larson: A study of the nature of the circulating thyroid hormone in euthyroid subjects by use of paper electrophoresis. J. Labor, a. Clin. Med. 40, 791 (1952).

    Google Scholar 

  • Dobyns, B. M.: Radioactive iodine as an adjunct to the surgical management of diseases of the thyroid. Surg. etc. 93, 415 (1951).

    CAS  Google Scholar 

  • Dobyns, B. M., and B. Lennon: A study of a histopathology and physiologic function of thyroid tumors, using radioactive iodine and radioautography. J. Clin. Endocrin. 8, 732 (1948).

    CAS  Google Scholar 

  • Dobyns, B. M., and B. Lennon: and F. MALOOF: The study and treatment of 119 cases of carcinoma of the thyroid with radioactive iodine. J. Clin. Endocrin. 11, 1323 (1951).

    CAS  Google Scholar 

  • Dobyns, B. M., and B. Lennon: B. SKANSE and F. MALOOF: A method for the preoperative estimation of function in thyroid tumors; its significance in diagnosis and treatment. J. Clin. Endocrin. 9, 1171 (1949).

    CAS  Google Scholar 

  • Dobyns, B. M., and B. Lennon: and S. L. S. Eelman: The thyroid stimulating hormone of the anterior pituitary as distinct from the exophthalmos producing substance. Endocrinology (Springfield, 111.) 52, 705 (1953).

    CAS  Google Scholar 

  • Dobyns, B. M., A. L. Vickery, F. Maloof and E. M. Chapman: Functional and histologic effects of therapeutic doses of radioactive iodine on the thyroid of man. J. Clin. Endocrin. 13, 548 (1953).

    CAS  Google Scholar 

  • Doering, P.: Die Messung der Jodspeicherung in der menschlichen Schilddrüse nach Gabe von Radiojod (Jod131). Klin. Wschr. 1956, 837.

    Google Scholar 

  • Doniach, I.: The effect of radioactive iodine alone and in combination with methylthiouracil upon tumor production in the rat’s thyroid gland. Brit. J. Cancer 7, 181 (1953).

    CAS  PubMed  Google Scholar 

  • Douglas, D. M., and A. T. Kennte: Thiouracil in toxic goiter; Late results in a personal series. Brit. Med. J. 1952 II, 1387.

    Google Scholar 

  • Dunlop, D. M., and C. F. Rolland: Antithyroid substance in the treatment of hyperthy-roidism. Proc. Roy. Soc. Med. 43, 937 (1950).

    CAS  PubMed  Google Scholar 

  • Egmark, A., L. G. Larsson, A. Liljestrand and I. Ragnhult: Iodine concentrating thyroid carcinomas. A report of three cases. Acta radiol. (Stockh.) 39, 423 (1953).

    CAS  Google Scholar 

  • Eichler, O., F. Hess, F. Linder U. K. Schmeiser: Zur Behandlung des Schilddrüsen-carcinoms mit Radiojod. Langenbecks Arch. 269, 19 (1951).

    CAS  Google Scholar 

  • Eiff, A. W. V., U. H. J. Jesdinsky: Die Bestimmung des „Grundumsatzes im engeren Sinn„ in der Diagnostik der Thyreotoxikosen. Klin. Wschr. 1954, 317.

    Google Scholar 

  • Eiff, A. W. V., U. H. J. Jesdinsky: u. W. MEYER-EPPLER: Elektromyointegrator, ein Gerät zur quantitativen Auswertung von Muskelaktionsströmen. Klin. Wschr. 1956, 484.

    Google Scholar 

  • Engstrom, W. W., and B. Markardt: Influence of Estrogen on thyroid function. J. Clin. Endocrin. 14, 215 (1954).

    CAS  Google Scholar 

  • Farquharson, R. F., and A. A. Squires: Inhibition of secretion of thyroid gland by continuous ingestion of substance. Trans. Assoc. Amer. Physicians 56, 87 (1941).

    CAS  Google Scholar 

  • Fauvert, D., Et S. Nicollo: Traitement de l’hyperthvroide par l’iode radioactif (J131). Semaine Hop. 1954, 4236.

    Google Scholar 

  • Feitelberg, S., P. S. Kaunitz, S. Silver, N. Simon, L. R. Wasserman and St. B. Yohalem: Hyperthyroidism, treatment with radioactive iodine. Arch. Int. Med. 85, 471 (1950).

    Google Scholar 

  • Fellenberg, Th. V.: Vorkommen von Jod in der Natur: Zusammenhang zwischen Kropf-häufigkeit und Jodgehalt der Umwelt. Biochem. Z. 52, 148 (1924).

    Google Scholar 

  • Fellinger, K, R. Höfer U. H. Vetter: Die Reproduzierbarkeit kurzzeitiger Radiojodunter-suchungen (Zugleich ein Beitrag zur klinischen Verwendung eines neuen radioaktiven Jodisotops J132). Wien. klin. Wschr. 1955, 712.

    Google Scholar 

  • Fellinger, K, R. Höfer U. H. Vetter: E. MANNHEIMER U. H. VETTER: Zur Kenntnis der pathophysiologischen Grundlagen der Diagnostik und Therapie der Schilddrüsenerkrankungen mit radioaktivem Jod. Strahlenther., Sonderbd. 33, 81 (1955).

    Google Scholar 

  • Fitting, W., U. A. W. V. Eiff: Über den diagnostischen Wert von Radiojodtest, Grundumsatz und “Grundumsatz im engeren Sinn” für die Beurteilung der Schilddrüsenfunktion. Klin. Wschr. 1956, 486.

    Google Scholar 

  • Fitzgerald, P. J.: The histological types of thyroid cancers and their respective abilities to store radioactive iodine as demonstrated by radioautograms. Brookhaven, Conf. Report on radioactive iodine, July 28 /30 (1948).

    Google Scholar 

  • Fitzgerald, P. J.: and F. W. FOOTE: The function of various types of thyroid carcinoma as revealed by the radioautographic demonstration of radioactive iodine (I131). J. Clin. Endocrin. 9, 1153 (1949).

    CAS  Google Scholar 

  • Fitzgerald, P. J.: and R. F. HILL: Concentration of I131 in thyroid cancer shown by radioautography in 100 consecutive cases: The relation of histological structure to function of thyroid cancer. Cancer (N. Y.) 3, 86 (1950).

    CAS  Google Scholar 

  • Frantz, V. K., R. P. Ball, A. S. Kesten and W. Wt. Palmer: Thyroid carcinoma with metastases, studied with radioactive iodine. Ann. Surg. 119, 668 (1944).

    CAS  PubMed  Google Scholar 

  • Frantz, V. K., R. P. Ball, A. S. Kesten and W. Wt. Palmer: W. G. LARSEN and A. JARETZKI: An evaluation of radioactive iodine therapy in metastatic thyroid cancer. J. Clin. Endocrin. 10, 1084 (1950).

    CAS  Google Scholar 

  • Fräser, R., J. D. Abbatt and F. S. Stewart: Radioiodine treatment of thyrotoxicosis: A single dose method following a drug preparation. Brit. J. Radiol. 27, 23 (1954).

    PubMed  Google Scholar 

  • Fräser, R., Q. J. G. Hobson, D. G. Arnott and E. W. Emery: The urinary excretion of radioiodine as a clinical test of thyroid function. Q. art. J. Med. N. S. 22, 99 (1953).

    Google Scholar 

  • Fräser, R., J. D. Abbatt and F. S. Stewart: E. H. QUIMBY and T. C. EVANS: Radioactive iodine studies of functional thyroid cancer. Radiology 51, 532 (1948).

    Google Scholar 

  • Fredrickson, D. S., P. H. Forsham and G. W. Thorn: The effect of massive cortisone therapy on measurements of thyroid function. J. Clin. Endocrin. 12, 541 (1952).

    CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: Thyroid function in normal and pathological states as revealed by radioactive iodine studies. I. Thyroid I131 uptake and turnover in euthyroid, hyperthyroid and hypothyroid subjects. II. Factors influencing uptake and turnover of I131 by thyroid gland. Metabolism 1, 26–48 (1952).

    CAS  PubMed  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: G. S. KURLAND and H. L. BLUMGART: The pathologic effects of I131 on the normal thvroid gland of man. J. Clin. Endocrin. 12, 1315 (1952).

    CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: D. L. CHAMOVITZ and A. L. URELES: A critical analysis of the quantitative I131 therapy of thyrotoxicosis. J. Clin. Endocrin. 12, 86 (1952).

    CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: A. L. URELES and S. HERTZ: Serum level of protein-bound radioactive iodine (I131) in the diagnosis of hyperthyroidism. Proc. Soc. Exper. Biol. a. Med. 70, 679 (1949).

    CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: and B. SEAMON: The serum level of protein bound radioactive iodine (I131) in the diagnosis of hyperthyroidism. Proc. Soc. Exper. Biol. a. Med. 70, 697 (1949).

    Google Scholar 

  • Freedberg, A. S., A. L. Ureles, M. F. Lesses and S. M. Gargill: Pulmonary metastatic lesion successfully treated with radioactive iodine. Report of a case of pulmonary metastases from a papillary adenocarcinoma of the thyroid. J. Amer. Med. Assoc. 144, 16 (1950).

    CAS  Google Scholar 

  • Freedberg, A. S., A. L. Ureles, M. F. Lesses and S. M. Gargill: Treatment of thyroid carcinoma with radioactive iodine (I131). Amer. J. Med. 11, 44 (1951).

    CAS  PubMed  Google Scholar 

  • Freedberg, A. S., A. L. Ureles, M. F. Lesses and S. M. Gargill: L. WOLSKY, G. S. KURLAND and M. W. HAMOLSKY: The thyroid hormonal pool in man and dog. J. Clin. Invest. 31, 628 (1952).

    Google Scholar 

  • Friedell, H. L., and A. M. Potts: I131 in the diagnosis and treatment of hyperthyroidism. Amer. J. Roentgenol. 64, 576 (1950).

    Google Scholar 

  • Gerbaulet, K., U. W. Fitting: Über das Jod-Konzentrierungs-und Sekretionsvermögen der Speicheldrüsen (Untersucht mit Jod131 bei Patienten mit unterschiedlicher Schild-drüsenfunktion). Klin. Wschr. 1956, 120.

    Google Scholar 

  • Gerbaulet, K., U. W. Maurer: Papierelektrophoretische und papierchromatographische Untersuchungen der organischen Jod-Verbindungen des Serums. Strahlenther., Sonderbd. 33, 116 (1955).

    Google Scholar 

  • Ghosh, B. N., D. M. Woodbury and G. Sayers: Quantitative effects of thyrotropic hormone on I131 accumulation in thyroid and plasma proteins of hypophysectomized rats. Endo-crinology (Springfield, 111.) 48, 631 (1951).

    CAS  Google Scholar 

  • Godley, A. F., and J. B. Stanbury: Preliminary experience in the treatment of hyper-thyroidism with Potassium Perchlorate. J. Clin. Endocrin. 14, 70 (1954).

    CAS  Google Scholar 

  • Goodwin, J. F., B. J. Duffy, P. J. Fitzgerald, I. B. Trunnell and R. W. Rawson: Pathological effects and radioautographic localization of I131 in humans. Post mortem study in nine patients. Cancer (N. Y.) 4, 936 (1951).

    Google Scholar 

  • Goldberg, R. C., and I. L. Chaikoff: On the nature of the hypertrophied pituitary gland induced in the mouse by I131 injections, and the mechanism of its development. Endocrinology (Springfield, 111.) 48, 1 (1951).

    CAS  Google Scholar 

  • Goldberg, R. C., and I. L. Chaikoff: Development of thyroid neoplasms in the rat following a simple injection of radio-active iodine. Proc. Soc. Exper. Biol. a. Med. 76, 563 (1951).

    CAS  Google Scholar 

  • Goldberg, R. C., S. Lindsay and D. D. Feller: Histopathological changes induced in the normal thyroid and other tissues of the rat by internal radiation with various doses of radioactive iodine. Endocrinology (Springfield, 111.) 46, 72 (1950).

    CAS  Google Scholar 

  • Goldsmith, R. E.: Experience with the radioiodine tracer test in radioiodine-treated thyro-toxic patients. Amer. J. Med. Sci. 227, 403 (1954).

    CAS  PubMed  Google Scholar 

  • Goldsmith, R. E., and E. L. Saenger: Results of therapy with radioactive iodine in hyperthyroidism. Ohio State Med. J. 50, 26 (1954).

    CAS  Google Scholar 

  • Goldsmith, R. E., J. B. Stanbury and G. L. Brownell: The effect of thyrotropin on the release of hormone from the human thyroid. J. Clin. Endocrin. 11, 1079 (1951).

    CAS  Google Scholar 

  • Goodwin, J. F., A. G. Macgregor, H. Miller and E. J. Wayne: The use of radioactive iodine in the assessment of thyroid function. Quart. J. Med. N. S. 20, 353 (1951).

    Google Scholar 

  • Goodwin, J. F., H. Miller and E. J. Wayne: A comparison of the antithyroid activity of paraamino-bezoic acid and thiouracil compounds. Lancet 1949 II, 1211.

    Google Scholar 

  • Goodwin, W. E.: Total accountable radioiodine. Combined thyroid uptake and urinary excretion of I131 in the study of thyroid function. Metabolism 2, 238 (1953).

    CAS  PubMed  Google Scholar 

  • Goodwin, W. E., B. Cassen and F. K. Bauer: Thyroid gland weight determinations from thyroid scinti-grams with post mortem verification. Radiology 61, 88 (1953).

    CAS  PubMed  Google Scholar 

  • Gorbman, A.: Degenerative and regenerative changes in the thyroid gland following high dosages of radioactive iodine. Trans. New York Acad. Sci. 11, 201 (1949).

    CAS  Google Scholar 

  • Gorbman, A.: Functional and structural changes consequent to high dosages of radioactive iodine. J. Clin. Endocrin. 10, 1177 (1950).

    CAS  Google Scholar 

  • Gorbman, A.: and H. M. EVANS: Beginning of function in the thyroid of the fetal rat. Endocrinologv (Springfield, 111.) 32, 113 (1943).

    CAS  Google Scholar 

  • Gordon, A. H., J. Gross, D. O’connor and R. Pitt-Rivers: Nature of the circulating thyroid hormone-plasma protein complex. Nature (London) 169, 19 (1952).

    CAS  Google Scholar 

  • Gordon, E. S., and E. C. Albright: Treatment of thyrotoxicosis with radioactive iodine. J. Amer. Med. Assoc. 143, 1129 (1950).

    CAS  Google Scholar 

  • Green, G. F., J. F. Tait and R. Worsnop: Some observations and problems of treatment with radioactive iodine (I131). Brit. J. Radiol. 24, 148 (1951).

    CAS  PubMed  Google Scholar 

  • Green, W. W., W. E. White, E. P. Engelmann and A. Krupp: Effect of butazolidin on I131 uptake by the thyroid gland. Proc. Soc. Exper. Biol. a. Med. 82, 155 (1953).

    CAS  Google Scholar 

  • Greer, M. A.: Correlation of the 24-hour radioiodine uptake of the human thyroid gland with the 6-and 8-hour uptakes and the “accumulation gradient”. J. Clin. Invest. 30, 301 (1951).

    CAS  PubMed  Google Scholar 

  • Greer, M. A., and G. E. Smith: Method for increasing accuracy of I131 uptake as test for thyroid function by use of dessicated thyroid. J. Clin. Endocrin. 14, 1374 (1954).

    CAS  Google Scholar 

  • Gros, H.: Untersuchungen über den Wirkungsmechanismus des Butazolidins. Klin. Wschr. 1956, 481.

    Google Scholar 

  • Gross, J., and R. Pitt-Rivers: Unidentified iodine compounds in human in addition to thyroxine and iodine. Lancet 1951II, 766.

    Google Scholar 

  • Gross, J., and R. Pitt-Rivers: Experimental study of thyroid metabolism with radioactive iodine. Brit. Med. Bull. 136, 8 (1952).

    Google Scholar 

  • Gross, J., and R. Pitt-Rivers: The identification of 3, 5, 3M-triiodothyronine in human plasma. Lancet 1952 I, 439.

    Google Scholar 

  • Guinet, P., Et M. Berger: L’épreuve à la thyréostimuline dans le diagnostic étio-pathogénique du myxoedème. Ann. d’Endocrin. 12, 585 (1951).

    CAS  Google Scholar 

  • Haines, S. F., F. R. Keating, M. H. Power, M. M. D. Williams and M. P. Kelsey: The use of radioiodine in the treatment of exophthalmic goiter. J. Clin. Endocrin. 8, 813 (1948).

    CAS  Google Scholar 

  • Hamilton, C. F., A. Albert and H. S. F. Powter: The behavior of labeled iodocasein in human myxedema. J. Clin. Endocrin. 9, 828 (1949).

    CAS  Google Scholar 

  • Hamilton, H. B., and S. C. Werner: Effect of sodium-iodide, propylthiouracil and methyl-mercaptoimidazol during radioiodine therapy of hyperthyroidism. J. Clin. Endocrin. 11, 763 (1951).

    Google Scholar 

  • Hamilton, H. B., and S. C. Werner: The effects of sodium iodide, 6-propylthiouracil, and l-methyl-2-mercaptoimidazole during radioiodine therapy of hyperthyroidism. J. Clin. Endocrin. 12, 1083 (1952).

    CAS  Google Scholar 

  • Hamilton, J. G.: The rates of absorption of the radioactive isotopes of sodium, potassium, chlorine, bromine and iodine in normal human subjects. Amer. J. Physiol. 124, 667 (1938).

    CAS  Google Scholar 

  • Hamilton, J. G.: The use of radioactive tracers in biology and medicine. Radiology 39, 341 (1942).

    Google Scholar 

  • Hamilton, J. G., C. W. Asling, W. M. Garrison and K. G. Scott: The accumulation, metabolism and biological effects of astatine in rats and monkevs. Univ. California (Berkeley) Publ. Pharmacol. 2, 283 (1953).

    Google Scholar 

  • Hamilton, J. G., and J. H. Lawrence: Recent clinical developments in the therapeutic application of radio-phosphorus and radioiodine. J. Clin. Invest. 21, 624 (1942).

    Google Scholar 

  • Hamilton, J. G., M. Parrott and P. Wallace-Durbin: The accumulation and destructive action of Astatine211 (eka-iodine) in the thyroid gland of rats and monkeys. J. Clin. Endocrin. 14, 1161 (1954).

    CAS  Google Scholar 

  • Hamilton, J. G., and M. H. Soley: A comparison of the metabolism of iodine and element 85 (eka-iodine). Proc. Nat, Acad. Sci. 26, 483 (1940).

    CAS  Google Scholar 

  • Hamilton, J. G., and K. B. Eichorn: Deposition of radioactive iodine in human thyroid tissue. Univ. California (Berkeley) Publ. Pharmacol. 1, 339 (1940).

    CAS  Google Scholar 

  • Hamilton, J. G., P. Wallace-Durbin and M. W. Parrott: Comparison of acute and chronic changes produced in rats by iodine 131 and astatine 211 at lethal levels. Preliminary clinical data on the uptake of astatine 211 in patients with thvroid disease. Proc. of Radioisotope Conf. 1, 212 (1954).

    Google Scholar 

  • Hamolsky, M. W., A. S. Freedberg, G. S. Kurland and L. Wolsky: The exchangeable thyroid hormonal pool. I. Its magnitude and rate of turnover in various thyroid states in man. J. Clin. Invest. 32, 453 (1953).

    CAS  Google Scholar 

  • Hanbury, E. M., J. Heslin, L. G. Stang, W. D. Tucker and J. E. Rall: The diagnostic use of J18?. J. Clin. Endocrin. 14, 1530 (1954).

    CAS  Google Scholar 

  • Hanngren, Ä.: Determination of the antithyroid action of para-amino-salicylic acid using radioactive iodine. Lancet 1952 II, 117.

    Google Scholar 

  • Harbers, E., U. P. Doering: Dosisfragen und Strahlenschädigungen bei Anwendung von Radioisotopen. Klin. Wschr. 1955, 777.

    Google Scholar 

  • Harington, C. R.: Chemistry of thvroxine. II. Isolation of thyroxine from the thvroid gland. Biochemic. J. 20, 293 (1926).

    CAS  Google Scholar 

  • Harington, C. R., and G. Barger: Chemistry of thyroxine. III. Constitution and synthesis of thyroxine. Biochemic. J. 21, 169 (1927).

    CAS  Google Scholar 

  • Harper, E. O., and P. A. Mattis: Federat, Proc. 10, 306 (1951); zit. bei W. HORST U. F. KUHLENCORDT (1954).

    Google Scholar 

  • Harsha, W. X.: Plasma protein-bound iodine determinations. Amer. J. Med. Sci. 221, 626 (1951).

    CAS  PubMed  Google Scholar 

  • Harsha, W. X.: Evaluation of the conversion of radioactive inorganic iodine to protein-bound iodine as a diagnostic aid in thyroid dysfunction. J. Clin. Endocrin. 11, 1524 (1951).

    CAS  Google Scholar 

  • Heidelberger, M., and W. W. Palmer: The preparation and properties of thvroglobulin. J. of Biol. Chem. 101, 433 (1933).

    CAS  Google Scholar 

  • Heidelberger, M., and K. O. Pedersen: Molecular weight and isoelectric point of the thvroglobulin. J. Gen. Physiol. 12, 95 (1935).

    Google Scholar 

  • Hertz, S., and A. Roberts: Application of radioactive iodine in therapv of Graves disease. J. Clin. Invest, 21, 624 (1942).

    Google Scholar 

  • Hertz, S., and R. D. Evans: Radioactive iodine as an indicator in the studv of thyroid physiology. Proc. Soc. Exper. Biol, a, Med. 38, 510 (1938).

    Google Scholar 

  • Herve, A., J. Closon Et J. Govaerts: Cancers thyroidiens et radio-iode. J. beige Radiol. 33, 216 (1950).

    CAS  Google Scholar 

  • Hill, S. R., R. S. Reiss, P. H. Forsham and S. W. Thorn: The effect of adrenocortico-tropin and cortisone on thyroid function: Thyroid-adrenocortical interrelationships. J. Clin. Endocrin. 10, 1375 (1950).

    Google Scholar 

  • Himsworth, H. P., M. E. Morgans and W. R. Trotter: Thyroidectomy and thiouracil in toxic goiter; interim comparison. Lancet 1947 I, 241.

    Google Scholar 

  • Hlad, Ch. J., and N. S. Bricker: Renal function and I131 clearance in hyperthyroidism and myxedema. J. Clin. Endocrin. 14, 1539 (1954).

    CAS  Google Scholar 

  • Hofmann-Credner, D.: Experimentelle Untersuchungen zur Jodaufnahme durch die Haut und Lunge beim Menschen. Arch, internat. Pharmacodynamic 97, 363 (1954).

    CAS  Google Scholar 

  • Hofmann-Credner, D., U. H. Spitzy: Zur Frage der perkutanen und respiratorischen Jodaufnahme. Arch, physik. Ther. 6, 171 (1954).

    CAS  Google Scholar 

  • Honour, A. J., N. B. Myant and E. N. Rowlands: Secretion of radioiodine in digestive juices and milk in man. Clin. Sci. 11, 447 (1952).

    CAS  Google Scholar 

  • Horst, W.: Zur diagnostischen Anwendung von Radiojod 131. Strahlenther. 85, 183 (1951).

    CAS  Google Scholar 

  • Horst, W.: Die Strahlentherapie der Schilddrüsenüberfunktion mit Radiojod 131. Dtsch. med. Wschr. 1951, 1052.

    Google Scholar 

  • Horst, W.: Methoden und Ergebnisse des Radiojodstoffwechsel-Studiums zur Diagnostik thyreoidaler und extrathyreoidaler Erkrankungen. Klin. Wschr. 1952, 439.

    Google Scholar 

  • Horst, W.: Neue Ergebnisse der Anwendung von J131 in Diagnostik und Therapie von Schilddrüsenerkrankungen. Strahlenther. 94, 169 (1954).

    CAS  Google Scholar 

  • Horst, W.: Indikationen und Behandlungserfolge der J131-Strahlentherapie von Schilddrüsen-erkrankungen unter Einbeziehung von Kreislauferkrankungen. Regensb. Jb. ärztl. Fortbild. 6, (1956).

    Google Scholar 

  • Horst, W., U. E. Gadermann: Ergebnisse der Strahlenresektion bzw. Elimination der Schilddrüse mit Radiojod bei fortgeschrittenen Herzerkrankungen. Strahlenther. 97, 87 (1955).

    CAS  Google Scholar 

  • Horst, W., U. F. Kuhlencordt: Ergebnisse der Strahlentherapie mit Radiojod (J131). Dtsch. med. Wschr. 1954, 399.

    Google Scholar 

  • Horst, W., U. H. Rösler: Der Transport des Hormonjods in menschlichem Serum untersucht mit Papierelektrophorese und Radiojod. Zugleich ein Beitrag zur Frage der Existenz von sog. Zwischen-Fraktionen. Klin. Wschr. 1953, 13.

    Google Scholar 

  • Houssay, A. B.: Acción de la adrenocorticotrofina y de la cortisona sobre la función tiroidea. Rev. Asoc. med. argent. 66, 132 (1952).

    CAS  PubMed  Google Scholar 

  • Huguenin, R., M. Ttjbiana, J. Abbatucci Et J. Dutreix: Méthodes de diagnostic et de sélection des cancers thyroidiens susceptibles d’être traités par l’iode radioactif. Bull. Assoc. franç. Étude Cane. 41, 322 (1954).

    CAS  Google Scholar 

  • Ingbar, S. H.: A new method for the study of thyroidal function in man, using radioactive iodine. J. Clin. Invest. 32, 577 (1953).

    Google Scholar 

  • Ingbar, S. H.: Simultaneous measurement of the iodide concentrating and protein-binding capacities of the normal and hyperfunctioning human thyroid gland. J. Clin. Endocrin. 15, 238 (1955).

    CAS  Google Scholar 

  • Ingbar, S. H., and B. F. Chandler: Influence of cortisone and desoxycorticosterone upon the renal and thyroidal metabolism of iodine. J. Clin. Endocrin. 13, 853 (1953).

    Google Scholar 

  • Ingbar, S. H., and N. Freinkel: The effect of cortisone and hydrocortisone on the peripheral utilization of thyroid hormone. J. Clin. Invest. 33, 945 (1954).

    Google Scholar 

  • Ingbar, S. H., P. D. Hoeprich and J. W. Athens: The concentration and significance of the butanol-extractable I131 of serum in patients with diverse states of thyroidal function. J. Clin. Invest. 33, 388 (1954).

    CAS  PubMed  Google Scholar 

  • Ingbar, S. H., P. D. Hoeprich and J. W. Athens: Simultaneous estimation of rates of thyroxine degradation and thyroid hormone synthesis. J. Clin. Invest. 24, 808 (1955).

    Google Scholar 

  • Iversen, K.: Late results from continuous treatment of thyrotoxicosis with M. T. U.; Late results. J. Clin. Endocrin. 11, 298 (1951).

    CAS  Google Scholar 

  • Jaffe, H. L., and R. E. Ottoman: Evaluation of radioiodine test for thyroid function. J. Amer. Med. Assoc. 143, 515 (1950).

    CAS  Google Scholar 

  • Jaffe, H. L., M. H. Rosenfeld, F. W. Pobirs and L. J. Stuppy: Treatment of advanced heart disease. Endresults in one hundred patients. J. Amer. Med. Assoc. 151, 716 (1953).

    CAS  Google Scholar 

  • Jagic, N. V., U. O. V. Zimmermann-Meinzingen: Totale Thyreoidektomie bei Herz-und Kreislauf-Kranken. Münch, med. Wschr. 1939, 245.

    Google Scholar 

  • Johnson, P. C., and W. H. Beierwaltes: The urinary and fecal excretion of I131 from labeled sodium-1-thyroxine in various thvroid states and in euthyroids with bile fistulas. J. Labor, a. Clin. Med. 41, 676 (1953).

    CAS  Google Scholar 

  • Johnston, M. A. W., A. H. Squires and R. F. Farquharson: The effect of prolonged administration of thyroid. Ann. Int. Med. 35, 1008 (1951).

    CAS  PubMed  Google Scholar 

  • Judd, E. S.: The role of the surgeon in thyrotoxicosis. Surg. Clin. N. Amer. 32, 981 (1952)

    Google Scholar 

  • Kaae, S.: The treatment of thyroid carcinoma with radioactive iodine. Acta radiol. (Stockh.) 33, 539 (1951).

    Google Scholar 

  • Kaae, S., and O. Petersen: The treatment of thyroid carcinoma with radioactive iodine. Acta radiol. (Stockh.) 33, 539 (1950).

    CAS  Google Scholar 

  • Keating, F., and A. Albert: The metabolism of iodine in man as disclosed with the use of radioiodine. Ree. Progr. in Hormone Res. 4, 429 (1949).

    Google Scholar 

  • Keating, F., and A. Albert: Distribution and metabolism of radioactive 1-triiodothyronine compared with radioactive 1-thyroxine in the rat. J. Clin. Invest. 32, 580 (1953).

    Google Scholar 

  • Keating, F., S. F. Haines, M. H. Power and M. M. D. Williams: The radioiodine-accumulating function of the human thyroid gland as a diagnostic test in clinical medicine. J. Clin. Endocrin. 10, 1425 (1950).

    Google Scholar 

  • Keating, F., M. H. Power, J. Berkson and S. F. Haines: The urinary excretion of radioiodine in various thyroid states. J. Clin. Invest. 26, 1138 (1947).

    CAS  Google Scholar 

  • Keating, F., R. W. Rawson, W. Peacock and R. D. Evans: The collection and loss of radioactive iodine compared with the anatomic changes induced in the thyroid of the duck by the injection of thyreotropic hormone. Endocrinology (Springfield, 111.) 36, 137 (1945).

    CAS  Google Scholar 

  • Keating, F., J. C. Wang, Th. J. Luellen, M. M. D. Williams, M. H. Powder and W. M. Mcconahey: The measurement of the iodine-accumulating function of the human thvroid gland. J. Clin. Invest. 28, 217 (1949).

    CAS  Google Scholar 

  • Kelly, F. J.: Observations on the calculation of thyroid weight, using empirical formulae. J. Clin. Endocrin. 14, 326 (1954).

    CAS  Google Scholar 

  • Kelsey, M. P., S. F. Haines and F. R. Keating: Radioiodine in the study and treatment of thyroid disease. A review. J. Clin. Endocrin. 9, 171 (1949).

    CAS  Google Scholar 

  • Kendall, E. C.: The isolation on crystalline form of the compound containing iodine which occurs in the thyroid; its chemical nature and phvsiological activity. Trans. Assoc. Amer. Physicians 30, 420 (1915).

    Google Scholar 

  • Keston, A. S., R. P. Ball, V. K. Frantz and W. W. Palmer: Storage of radioactive iodine in a metastasis from thyroid carcinoma. Science (Lancaster, Pa.) 95, 362 (1942).

    CAS  Google Scholar 

  • Kirkland, R. H.: Impaired organic binding of radioiodine by the thyroid following radio-iodine treatment of hyperthyroidism. J. Clin. Endocrin. 14, 565 (1954).

    CAS  Google Scholar 

  • Klein, E.: Verschiedene Zustandsformen der Schilddrüsenhormone im Blut. Acta endocrinol. (Copenh.) 18, 22 (1955).

    CAS  Google Scholar 

  • Kohl, D., G. Moore and S. Chou: A scintillation counter for clinical use. Nucleonics 9, 68 (1951).

    CAS  PubMed  Google Scholar 

  • Koneff, A. A., C. W. Nichols, J. Wolff and I. L. Chaikoff: The fetal bovine thyroid: Morphogenesis as related to iodine accumulation. Endocrinologv (Springfield, 111.) 45. 242 (1949).

    CAS  Google Scholar 

  • Kreutzer, F. L., E. R. Miller, M. H. Soley and S. Lindsay: Histologie localization of absorbed radioactive iodine in some human thyroid diseases. Arch. Surg. 60, 707 (1950).

    CAS  Google Scholar 

  • Kriss, P.: Uptake of radioactive iodine, I131, by the thyroid gland after administration of tracer doses. J. Clin. Endocrin. 10, 812 (1950).

    CAS  Google Scholar 

  • Kühne, P., U. H. Billion: Die Altersregression der Schilddrüsenfunktion im Radiojodtest. Ärztl. Wschr. 1955, 62.

    Google Scholar 

  • Kühl, W. J., and M. Ziff: Alternation of thyroid function by ACTH and Cortisone. J. Clin. Endocrin. 12, 554 (1952).

    Google Scholar 

  • Kurland, G. S., D. L. Chamovitz and A. S. Freedberg: The distribution and the pathologie effects of I131 in man. J. Clin. Invest. 29, 829 (1950).

    CAS  PubMed  Google Scholar 

  • Kurland, G. S., and A. S. Freedberg: The distribution of I131 in tissue obtained at necropsy or at surgical operation in man. J. Clin. Endocrin. 11, 843 (1951).

    CAS  Google Scholar 

  • Kurland, G. S., and J. Fishman: Effect of thyrotropin on changes in thyroid function following administration of I131 to euthyroid cardiac patients. J. Clin. Endocrin. 14, 572 ( 1954;

    Google Scholar 

  • Lamberg, B. A.: Acta med. scand. (Stockh.) 148, 225 (1954); zit. bei H. SAUTER (1956).

    Google Scholar 

  • Larson, F. C., W. P. Deiss and E. C. Albright: Localization of protein bound radioactive iodine by filter paper electrophoresis. Science (Lancaster, Pa.) 115, 626 (1952).

    CAS  Google Scholar 

  • Larsson, L. G.: Acta radiol. (Stockh.) Suppl. 126, 38 (1955); zit. bei H. BRÜGEL (1956).

    Google Scholar 

  • Larsson, L. G., and J. Ragnhult: A study of the iodine-concentrating function of the thyroid after treatment with radioactive iodine. Acta radiol. (Stockh.) 39, 477 (1952).

    Google Scholar 

  • Leblond, C. P., M. B. Fertman, I. D. Puppel and G. M. Curtis: Radioiodine autography in studies of human goitrous thyroid glands. Arch, of Path. 41, 510 (1946).

    CAS  Google Scholar 

  • Larsson, L. G., and J. Gross: The mechanism of the secretion of thyroid hormone. J. Clin. Endocrin. 9, 149 (1949).

    Google Scholar 

  • Larsson, L. G., and W. Mann: Function of iodine by the thyroid of rats given diets deficient in iodine. Proc. Soc. Exper. Biol. a. Med. 49, 102 (1942).

    Google Scholar 

  • Larsson, L. G., Et J. Sue: Passage de l’iode radioactif (J128) dans la thyroide stimulée par l’hormone thyreotrope de l’hypophyse. C. r. Soc. Biol. (Paris) 133, 543 (1940).

    Google Scholar 

  • Leblond, C. P., J. Sue: Iodine fixation in the thyroid as influenced by hypophysis and other factors. Amer. J. Physiol. 134, 549 (1941).

    CAS  Google Scholar 

  • Leiter, L., S. M. Scidlin, L. D. Marinelli and E. J. Baumann: The effect of thiouracil on hyperthyroidism and on the uptake of radioactive iodine in patients with adeno-carcinoma of the thyroid and functioning metastases. J. Clin. Invest. 23, 941 (1944).

    Google Scholar 

  • Leiter, L., S. M. Scidlin, L. D. Marinelli and E. J. Baumann: Adenocarcinoma of the thyroid with hyperthyroidism and functioning metastases. I. Studies with thiouracil and radio-iodine. J. Clin. Endocrin. 6, 247 (1946).

    CAS  Google Scholar 

  • Letton, A. H., and J. P. Wilson: Cancer of the thyroid. J. Internat. Coll. Surg., Chicago 24, 79 (1955).

    CAS  Google Scholar 

  • Levy, R. P., L. W. Kelly and W. M. Jefferies: The study of thyroid function by means of a single injection of thyrotropin. J. Clin. Invest. 32, 583 (1953).

    Google Scholar 

  • Levy, R. P., L. W. Kelly and W. M. Jefferies: The relationship between changes in thyroidal I131 uptake and serum protein-bound iodine following thyrotropin. J. Clin. Invest. 33, 953 (1954).

    Google Scholar 

  • Lewis, J. W.: Simplified method for determining thyroid function with radioiodine. Nucleonics 12, 59 (1954).

    Google Scholar 

  • Lindeboom, G. A., T. E. Hoogendijk Van Dort and J. De Jong: Blood levels of I131 after tracer doses in patients with thyrotoxicosis with radioiodine. Acta med. scand. (Stockh.) 150, 487 (1955).

    CAS  Google Scholar 

  • Linder, F., U. F. Ruf: Schilddrüsen-Carcinom und Radiojod. Künstliche Radioaktive Isotope in Physiologie, Diagnostik und Therapie. Berlin-Göttingen-Heidelberg: Springer-Verlag 1953.

    Google Scholar 

  • Loeser, A.: Über endokrine Jodwirkungen, ihre Streuung und medikamentöse Beeinflussung. Dtsch. med. Wschr. 1950, 36.

    Google Scholar 

  • Luellen, T. J., F. R. Keating, M. M. D. Williams, J. Bergson, M. J. Power and W. M. Mcconahey: Relative measurement in vivo of accumulation of radioiodine by the human thyroid gland: Comparison with radioactivity in peripheral tissues. J. Clin. Invest. 28, 207 (1948).

    Google Scholar 

  • Macgregor, A. G.: Radioactive iodine in the diagnosis of thyrotoxicosis. Brit. J. Radiol. 23, 550 (1950).

    CAS  PubMed  Google Scholar 

  • Macintyre, W. J.: A scintillation counter for measurement of I131 uptake in the thyroid gland. Proc. Soc. Exper. Biol. a. Med. 75, 561 (1950).

    CAS  Google Scholar 

  • Mack, R. E.: The use of radioactive iodine in the diagnosis and treatment of hyperthyroidism. Missouri Med. 50, 267 (1953).

    CAS  PubMed  Google Scholar 

  • Maloof, F., and E. M. Chapman: Responses to radioactive iodine therapy in hyperthyroidism, with special reference to cardiac problems. J. Clin. Endocrin. 11, 1296 (1951).

    CAS  Google Scholar 

  • Maloof, F., B. M. Dobyns and S. L. Vickery: The effects of various doses of radioactive iodine on the function and structure of the thyroid of the rat. Endocrinology (Springfield, 111.) 50, 612 (1952).

    CAS  Google Scholar 

  • Mandl, F., U. E. Singer: Thyreoidektomie bei Herzkranken. Wien. klin. Wschr. 1936 II, 1355.

    Google Scholar 

  • Marine, D., and A. Johnson: Experimental observations on the effects of the administration of iodine in three cases of thyroid carcinoma. Arch. Int. Med. 2, 228 (1913).

    Google Scholar 

  • Marine, D., and J. M. Rogoff: The absorption of potassium iodide by the thyroid gland in vivo, following its intravenous injection in constant amounts. J. Pharmacol. 8, 439 (1916).

    CAS  Google Scholar 

  • Marinelli, L. D.: Dosage determination in the use of radioactive isotopes. J. Clin. Invest. 28, 1271 (1949).

    CAS  PubMed  Google Scholar 

  • Marinelli, L. D., F. W. Foote, R. F. Hill and A. Hocker: Retention of radioactive iodine in thyroid carcinomas; histopathologic and radioautographic studies. Amer. J. Roentgenol. 58, 17 (1947).

    CAS  Google Scholar 

  • Marinelli, L. D., U. R. F. Hill: Studies on dosage in cancer therapy. Brookhaven Conf. Rep. on radio-iodine Assoc., Univ., Inc., Upton, N. Y. p. 98, 1948.

    Google Scholar 

  • Marinelli, L. D., U. R. F. Hill: Radiation dosimetry in the treatment of functional thyroid carcinoma with I131. Radiology 55, 494 (1950).

    CAS  PubMed  Google Scholar 

  • Marinelli, L. D., E. H. Quimby and G. J. Hine: Dosage determination with radioactive isotopes. II. Practical considerations in therapy and protection. Amer. J. Roentgenol. 59, 260 (1948).

    CAS  Google Scholar 

  • Marinoni, U., E C. Picchio: Tumori della tiroide e iodio radioattivo. Radiol, med. 40, 790 (1954).

    CAS  Google Scholar 

  • Martin, J. M., and J. B. Stanbury: The response of the I131-treated thyroid gland to thyro-tropic hormone. J. Clin. Endocrin. 15, 811 (1955).

    CAS  Google Scholar 

  • Martint, P.: Diagnostik und Therapie der Hyperthyreose. Dtsch. med. Wschr. 1955, 1625.

    Google Scholar 

  • Mason, A S., and R. Olivier: Urinary excretion of radioactive iodine as a diagnostic aid in thyroid disorders. Lancet 1949 II, 456.

    Google Scholar 

  • Maurer, W., U L. Reichenbach: Über die Bindung des organischen Jods im Serum an einzelne Serum Eiweißfraktionen. Naturwiss. 39, 261 (1952).

    CAS  Google Scholar 

  • Mayneord, W. V., and W. K. Sinclair: A dosimetry of artificial radioactive isotopes. Adv. Biol. Med. Phys N. Y. 3, 1 (1953).

    CAS  Google Scholar 

  • Mcarthur, J. W., R. W. Rawson, R. G. Fluharty and J. H. Means: The urinary excretion of radioactive iodine as an aid in diagnosis of hyperthyroidism. Ann. Int. Med. 29, 229 (1948).

    CAS  PubMed  Google Scholar 

  • Mcconahey, W. M., F. R. Keating and M. H. Power: An estimation of the renal and extrarenal clearance of radioiodine in man. J. Clin. Invest. 30, 778 (1951).

    CAS  PubMed  Google Scholar 

  • Mccullagh, E. P.: Radioactive iodine in the treatment of hyperthvroidism. Ann. Int. Med. 37, 739 (1952).

    CAS  PubMed  Google Scholar 

  • Mccullagh, E. P., A. Gold and J. B. R. Mckendry: Radioactive iodine uptake in the hypermetabolism of acromegaly. J. Clin. Endocrin. 10, 687 (1950).

    CAS  Google Scholar 

  • Mccullagh, E. P., and C. E. Richards: Radioactive iodine in the treatment of hyperthvroidism. xlrch. Int. Med. 87, 4 (1951).

    CAS  Google Scholar 

  • Mcgavack, T. H.: The current treatment of hyperthyroidism. Med. Clin. N. Amer. 37, 695 (1953).

    Google Scholar 

  • Mcginty, D. A., and E. A. Sharp: Effect of iodine intake on thyroid iodine distribution and thyroid weight of rats treated with thiouracil and other goitrogens. J. Clin. Endocrin. 6, 473 (1946).

    Google Scholar 

  • Meckstroth, C. V., and G. M. Curtis: Criteria for therapy of malignant thyroid lesions with I131. Arch. Surg. 67, 187 (1953).

    CAS  Google Scholar 

  • Meissner, J., J. Kracht U. W. Diller: Nachweis der Schreckthyreotoxikose des Wild-kaninchens mit radioaktivem Jod. Arch, exper. Path. u. Pharmakol. 216, 424 (1952).

    CAS  Google Scholar 

  • Middlesworth, L. Van: Metabolism of I131 in severe anoxia. Science (Lancaster, Pa.) 110, 120 (1949).

    Google Scholar 

  • Middlesworth, L. Van, and M. M. Berry: Iodide metabolism during anoxia, nephrectomy, trauma, avitaminoses and starvation in the rat. Amer. J. Physiol. 167, 576 (1951).

    Google Scholar 

  • Migeon, C. J., L. I. Gardner, J. F. Crigler and L. Wilkins: Effect of cortisone treatment for 28 days on radio-iodine metabolism in normal rats and adrenalectomized rats main-tained with desoxycorticosterone. Endocrinology (Springfield, 111.) 51, 117 (1952).

    CAS  Google Scholar 

  • Miller, E. R., M. E. Dailey and H. J. Mccorkle: Evaluation of treatment of hyperthyroidism with radioiodine. Arch. Surg. 65, 12 (1952).

    CAS  Google Scholar 

  • Miller, E. R., A. V. Holmes, G. L. Alexander and G. E. Sheline: Studies with radioiodine. I. Function and rate of I131 uptake of thyroid. Radiology 57, 37 (1951).

    CAS  Google Scholar 

  • Miller, E. R., M. H. Soley, N. Foreman, A. V. Holmes, G. L. Alexander and G. E. Sheline: Studies with radioiodine. II. Treatment of patients with hyperthyroidism by I131. Radiology 57, 227 (1951).

    CAS  PubMed  Google Scholar 

  • Miller, E. R., and G. E. Sheline: Studies with radioiodine. III. Problems of dosage in the treatment of hyperthyroidism. Radiology 57, 72 (1951).

    Google Scholar 

  • Miller, O. B., W. A. Selle and T. Gibbs: Studies in percutaneous absorption of radioiodine. J. Invest. Dermat. 12, 19 (1949).

    CAS  Google Scholar 

  • Mitchell, J. S.: Practical aspects of radioactive isotopes in relation to medical treatment. Brit. Med. J. 1951, No. 4734, 747.

    Google Scholar 

  • Moe, R. H., E. E. Adams, J. H. Rule, M. C. Moore, J. E. Kearns and D. E. Clark: An evaluation of radioactive iodine in the treatment of hyperthyroidism. J. Clin. Endocrin. 10, 1022 (1950).

    CAS  Google Scholar 

  • Money, W. L., P. J. Fitzgerald, J. T. Godwin and R. W. Rawson: The effect of thiouracil on the collection of radioactive iodine in experimentally induced thyroid tumors. Cancer (N. Y.) 6, 11 (1953).

    Google Scholar 

  • Money, W. L., J. E. Rall and R. W. Rawson: The effect of low iodine diet on thyroid function in rat. J. Clin. Endocrin. 12, 1495 (1952).

    CAS  Google Scholar 

  • Morgans, M. F., A. K. Oldham and W. R. Trotter: The effect of exogenous thyroxine on radioiodine uptake in normal subjects and in cases of thyrotoxicosis in remission. J. of Endocrin. 8, 250 (1952).

    CAS  Google Scholar 

  • Morgans, M. E., and W. R. Trotter: Treatment of thyrotoxicosis with potassium Perchlorate. Lancet 1954 I, 749.

    Google Scholar 

  • Morris, H. P.: The experimental development and metabolism of thyroid gland tumors. Adv. Cancer Res. 3, 51–115 (1955), Acad. Press. Inc. Publishers.

    Google Scholar 

  • Morton, M. E., I. L. Chaikoff and S. Rosenfeld: Inhibiting effect of inorganic iodide on the formation in vitro of tissue with radioactive iodine as indicator. J. of Biol. Chem. 147, 1 (1943).

    CAS  Google Scholar 

  • Morton, M. E., I. Perlman, E. Anderson and I. L. Chaikoff: Radioactive iodine as an indicator of the metabolism of iodine. V. The effects of hypophysectomy on the distribution of labeled thyroxine and diiodotyrosine in thyroid gland and plasma. Endocrinologv (Spring-field, 111.) 30, 495 (1942).

    Google Scholar 

  • Muller, H. J.: Gene mutations caused bv radiation. Symposium on Radiobiolgy (N. Y. ) 1952, 296–332.

    Google Scholar 

  • Müller, J. H., U. H. Aeppli: Über die Verwendung von Radiojod (J131) als Indikator der Schilddrüsenfunktion nach Einwirkung von Gonadotropin, männlichen und weiblichen Sexualhormonen. Experientia (Basel) o, 297 (1949).

    Google Scholar 

  • Mueller, R., C. C. Brausch, E. Z. Hirsch, R. S. Benua and B. M. Dobyns: Uptake of radioactive iodine in the thyroid of patients with impaired liver function. J. Clin. Endocrin. 14, 1287 (1954).

    CAS  Google Scholar 

  • Muylder, E. De, Et J. Maisin: Valeur comparative du métabolisme de base de l’excrétion urinaire d’iode marqué comme test de la fonction thyroidienne. Ann. d’Endocrin. 12, 1098 (1951).

    Google Scholar 

  • Myant, N. B.: Prognostic value of early tests of thyroid function after treatment of thyrotoxicosis by I131. Brit. J. Radiol. 26, 139 (1953).

    CAS  PubMed  Google Scholar 

  • Myant, N. B., B. D. Corbett, A. J. Honour and E. E. Pochin: Distribution of radioiodide in man. Clin. Sci. 9, 405 (1950).

    CAS  Google Scholar 

  • Myant, N. B., A. J. Honour and E. E. Pochin: Estimation of radioiodine in the thyroid gland of living subjects. Clin. Sci. 8, 135 (1949).

    CAS  PubMed  Google Scholar 

  • Myant, N. B., and E. E. Pochin: The thyroid clearance rate of plasma iodine and a measure of thyroid activity. Proc. Roy. Soc. Med. 42, 959 (1949).

    CAS  PubMed  Google Scholar 

  • Myant, N. B.: The metabolism of radiothyroxine in man. Clin. Sci. 9, 421 (1950).

    CAS  Google Scholar 

  • Myant, N. B., and E. A. G. Goldie: The plasma iodide clearance rate of the human thyroid. Clin. Sci. 8, 109 (1949).

    CAS  PubMed  Google Scholar 

  • Nelson, N., E. D. Palmes, C. R. Park, P. P. Weymouth and W. B. Bean: The absorption, excretion, and physiological effect of iodine in normal human subjects. J. Clin. Invest. 26, 301 (1947).

    CAS  Google Scholar 

  • Nicholson, J. P., C. W. Wilson and K. A. Newton: The distribution of radioiodine observed in thyroid disease by means of GEIGER counters-Its determination and significance. Amer. J. Roentgenol. 72, 849 (1954).

    CAS  PubMed  Google Scholar 

  • Nicholson, J. P., and R. G. C. Maclaren: The use of radioiodine in the study of thyroid disorders. Radiology 64, 567 (1955).

    CAS  PubMed  Google Scholar 

  • Nodine, J. H., W. H. Perloff, D. De Albuquergue, L. Perczek and B. Channick: The diphasic character of thyreoidal I131 clearance. J. Clin. Endocrin. 15, 347 (1955).

    CAS  Google Scholar 

  • Oberdisse, K.: Die Behandlung der Hyperthyreosen mit antithyreoidalen Substanzen. Dtsch. med. Wschr. 1956, 506.

    Google Scholar 

  • Oddie, T. H., I. Meschen and J. T. Wortham: Thyroid function assay with radioiodine III. Clinical test results and diagnostic limits for rate constants. J. Clin. Invest. 24, 1044 (1955).

    Google Scholar 

  • Oddie, T. H., and R. K. Scott: External measurement of radio-iodine in the thyroid gland. Brit. J. Radiol. 22, 698 (1949).

    CAS  PubMed  Google Scholar 

  • Oddie, T. H., and R. K. Scott: Results of uptake and excretion test with radio-iodine. Brit. J. Radiol. 23, 349 (1950).

    Google Scholar 

  • Odenthal, F.: Die Behandlung der Thyreotoxikose mit radioaktivem Jod. Dtsch. med. Wschr. 1954, 1568.

    Google Scholar 

  • Oeff, K., K. Kreutz U. M. Kessel: J131-Clearance der normalen und pathologischen Magen-schleimhaut. Klin. Wschr. 1955, 59.

    Google Scholar 

  • Oeser, H., H. Billion U. H. G. Mehl: Die Behandlung der Hyperthyreosen mit Radiojod. Künstliche Radioaktive Isotope in Physiologie, Diagnostik und Therapie. S. 798–825. Berlin-Göttingen-Heidelberg: Springer-Verlag 1953.

    Google Scholar 

  • Oliver, R.: Use of a scintillation gamma counter for the estimation of iodine 131 in liquid samples. Brit. J. Radiol. 26, 663 (1953).

    CAS  PubMed  Google Scholar 

  • Owen, C. A., and M. H. Power: Distribution of iodide between cells and plasma as measured by means of radioactive iodide. J. of Biol. Chem. 200, 111 (1953).

    CAS  Google Scholar 

  • Papper, S., B. A. Burrows, S. H. Ingbar, J. H. Sisson and J. F. Ross: The effects of 1-thyroxine sodium on nontoxic goiter, on myxedema and on the thyroid uptake of radioactive iodine. New England J. Med. 247, 897 (1952).

    CAS  Google Scholar 

  • Paschkis, K. E., A. Cantarow, E. Eberhard and D. Boyle: Thyroid function in the alarm reaction. Proc. Soc. Exper. Biol. a. Med. 73, 116 (1950).

    CAS  Google Scholar 

  • Paterson, R.: The treatment of thyroid carcinoma by radioiodine. Brit. J. Radiol. 23, 553 (1950).

    CAS  PubMed  Google Scholar 

  • Perinetti, H., E. B. Del Castillo, J. E. Itoiz, J. B. Stanbury, G. L. Brownell, D. S. Riggs, E. Trucco, A. Houssay Y A. G. Yaciofano: La glandula tiroidea humana déficiente en yodo. Medicina (Buenos Aires) 12, 17 (1952).

    CAS  Google Scholar 

  • Perlmutter, M., and D. S. Riggs: Thyroid collection of radioactive iodide and serum protein-bound iodine concentration in senescence, in hyperthyroidism and hypo-pituitarism. J. Clin. Endocrin. 9, 430 (1949).

    CAS  Google Scholar 

  • Perlmutter, M., S. Weisenfeld, S. Slater, E. Wallace and M. M. David: A study of the mechanism of the inhibition of the thyroid gland induced by ingestion of thyroid substance. J. Clin. Endocrin. 12, 208 (1952). Ergebnisse d. inn. Medizin, N. F. Bd. 8 17

    Google Scholar 

  • Müller, J. H., U. H. Aeppli: Über die Verwendung von Radiojod (J131) als Indikator der Schilddrüsenfunktion nach Einwirkung von Gonadotropin, männlichen und weiblichen Sexualhormonen. Experientia (Basel) o, 297 (1949).

    Google Scholar 

  • Mueller, R., C. C. Brausch, E. Z. Hirsch, R. S. Benua and B. M. Dobyns: Uptake of radioactive iodine in the thyroid of patients with impaired liver function. J. Clin. Endocrin. 14, 1287 (1954).

    CAS  Google Scholar 

  • Muylder, E. De, Et J. Maisin: Valeur comparative du métabolisme de base de l’excrétion urinaire d’iode marqué comme test de la fonction thyroidienne. Ann. d’Endocrin. 12, 1098 (1951).

    Google Scholar 

  • Myant, N. B.: Prognostic value of early tests of thyroid function after treatment of thyrotoxicosis by I131. Brit. J. Radiol. 26, 139 (1953).

    CAS  PubMed  Google Scholar 

  • Myant, N. B., B. D. Corbett, A. J. Honour and E. E. Pochin: Distribution of radioiodide in man. Clin. Sci. 9, 405 (1950).

    CAS  Google Scholar 

  • Myant, N. B., A. J. Honour and E. E. Pochin: Estimation of radioiodine in the thyroid gland of living subjects. Clin. Sci. 8, 135 (1949).

    CAS  PubMed  Google Scholar 

  • Myant, N. B., and E. E. Pochin: The thyroid clearance rate of plasma iodine and a measure of thyroid activity. Proc. Roy. Soc. Med. 42, 959 (1949).

    CAS  PubMed  Google Scholar 

  • Myant, N. B:., The Metabolism Of Radiothyroxine In Man. Clin. Sci. 9, 421 (1950).

    CAS  Google Scholar 

  • Myant, N. B., and E. A. G. Goldie: The plasma iodide clearance rate of the human thyroid. Clin. Sci. 8, 109 (1949).

    CAS  PubMed  Google Scholar 

  • Nelson, N., E. D. Palmes, C. R. Park, P. P. Weymouth and W. B. Bean: The absorption, excretion, and physiological effect of iodine in normal human subjects. J. Clin. Invest. 26, 301 (1947).

    CAS  Google Scholar 

  • Nicholson, J. P., C. W. Wilson and K. A. Newton: The distribution of radioiodine observed in thyroid disease by means of GEIGER counters-Its determination and significance. Amer. J. Roentgenol. 72, 849 (1954).

    CAS  PubMed  Google Scholar 

  • Nicholson, J. P., and R. G. C. Maclaren: The use of radioiodine in the study of thyroid disorders. Radiology 64, 567 (1955).

    CAS  PubMed  Google Scholar 

  • Nodine, J. H., W. H. Perloff, D. De Albuquergue, L. Perczek and B. Channick: The diphasic character of thyreoidal I131 clearance. J. Clin. Endocrin. 15, 347 (1955).

    CAS  Google Scholar 

  • Oberdisse, K.: Die Behandlung der Hyperthyreosen mit antithyreoidalen Substanzen. Dtsch. med. Wschr. 1956, 506.

    Google Scholar 

  • Oddie, T. H., I. Meschen and J. T. Wortham: Thyroid function assay with radioiodine III. Clinical test results and diagnostic limits for rate constants. J. Clin. Invest. 24, 1044 (1955).

    Google Scholar 

  • Oddie, T. H., and R. K. Scott: External measurement of radio-iodine in the thyroid gland. Brit. J. Radiol. 22, 698 (1949).

    CAS  PubMed  Google Scholar 

  • Oddie, T. H., and R. K. Scott: Results of uptake and excretion test with radio-iodine. Brit. J. Radiol. 23, 349 (1950).

    Google Scholar 

  • Odenthal, F.: Die Behandlung der Thyreotoxikose mit radioaktivem Jod. Dtsch. med. Wschr. 1954, 1568.

    Google Scholar 

  • Oeff, K., K. Kreutz U. M. Kessel: J131-Clearance der normalen und pathologischen Magen-schleimhaut. Klin. Wschr. 1955, 59.

    Google Scholar 

  • Oeser, H., H. Billion U. H. G. Mehl: Die Behandlung der Hyperthyreosen mit Radiojod. Künstliche Radioaktive Isotope in Physiologie, Diagnostik und Therapie. S. 798–825. Berlin-Göttingen-Heidelberg: Springer-Verlag 1953.

    Google Scholar 

  • Oliver, R.: Use of a scintillation gamma counter for the estimation of iodine 131 in liquid samples. Brit. J. Radiol. 26, 663 (1953).

    CAS  PubMed  Google Scholar 

  • Owen, C. A., and M. H. Power: Distribution of iodide between cells and plasma as measured by means of radioactive iodide. J. of Biol. Chem. 200, 111 (1953).

    CAS  Google Scholar 

  • Papper, S., B. A. Burrows, S. H. Ingbar, J. H. Sisson and J. F. Ross: The effects of 1-thyroxine sodium on nontoxic goiter, on myxedema and on the thyroid uptake of radioactive iodine. New England J. Med. 247, 897 (1952).

    CAS  Google Scholar 

  • Paschkis, K. E., A. Cantarow, E. Eberhard and D. Boyle: Thyroid function in the alarm reaction. Proc. Soc. Exper. Biol. a. Med. 73, 116 (1950).

    CAS  Google Scholar 

  • Paterson, R.: The treatment of thyroid carcinoma by radioiodine. Brit. J. Radiol. 23, 553 (1950).

    CAS  PubMed  Google Scholar 

  • Perinetti, H., E. B. Del Castillo, J. E. Itoiz, J. B. Stanbury, G. L. Brownell, D. S. Riggs, E. Trucco, A. Houssay Y A. G. Yaciofano: La glandula tiroidea humana déficiente en yodo. Medicina (Buenos Aires) 12, 17 (1952).

    CAS  Google Scholar 

  • Perlmutter, M., and D. S. Riggs: Thyroid collection of radioactive iodide and serum protein-bound iodine concentration in senescence, in hyperthyroidism and hypo-pituitarism. J. Clin. Endocrin. 9, 430 (1949).

    CAS  Google Scholar 

  • Perlmutter, M., S. Weisenfeld, S. Slater, E. Wallace and M. M. David: A study of the mechanism of the inhibition of the thyroid gland induced by ingestion of thyroid substance. J. Clin. Endocrin. 12, 208 (1952). Ergebnisse d. inn. Medizin, N. F. Bd. 8 17

    Google Scholar 

  • Rawson, R. W., J. E. Rall and W. Peacock: Limitations and indications in the treatment of cancer of the thyroid with radioactive iodine. J. Clin. Endocrin. 11, 1128 (1951).

    CAS  Google Scholar 

  • Rawson, R. W., and J. Robbins: Uses and misuses of radioactive iodine in treatment of cancer of thyroid. Arch. Int. Med. 92, 299 (1953).

    CAS  Google Scholar 

  • Rawson, R. W., B. N. Skanse, L. D. Marinelli and R. G. Fluharty: Radioactive iodine, its use in studying certain functions of normal and neoplastic thyroid tissues. Cancer (N. Y.) 2, 279 (1949).

    CAS  Google Scholar 

  • Rawson, R. W., and J. Trunnell: Radioactive iodine in the study and treatment of carcinoma of the thyroid. (A manual of artifical radioisotope therapy, Chapter VII. New York: Academic Press., Inc. N. Y. 1951.

    Google Scholar 

  • Redon, H., M. Tubiana, J. Abbatucci Et Fortier: Exploration thyrodienne par forage biopsique (drilling-ponction), mesures de radioactivité et autoradiographie des fragments prélevés. Ann. d’Endocrin. 14, 450 (1953).

    CAS  Google Scholar 

  • Reid, Q. F., and J. A. Sorenson: Effective thyroid depth and compensating measurements for iodine uptake determination. Radiology 58, 390 (1952).

    CAS  PubMed  Google Scholar 

  • Reiss, M., C. P. Haigh, R. E. Hemphill, R. Maggs, J. M. Reiss and S. Smith: Studies of the human thyroid function, measured by radioiodine, and its relation to the basal metabolic rate. J. of Endocrin. 8, 1 (1952).

    CAS  Google Scholar 

  • Reynolds, L., K. E. Corrigan and H. S. Hayden: Diagnostic use of radioactive isotopes. Amer. J. Roentgenol. 68, 421 (1952).

    CAS  PubMed  Google Scholar 

  • Richards, C. E. S G. Crile and E. P. Mccullagh: Radioactive iodine in the treatment of the hyperthyroidism of nodular goiter. J. Clin. Endocrin. 10, 1077 (1950).

    CAS  Google Scholar 

  • Riggs, D. S., E. B. Man and Winkler: Serumjodide of euthyroid subjects treated with disseccated thyroid. J. Clin. Invest. 24, 722 (1945).

    CAS  PubMed  Google Scholar 

  • Rigler, R. G., and P. W. Scanton: Radiation parotitis from radioactive iodine therapv. Proc. Staff Meet. Mayo Clin. 30, 149 (1955).

    CAS  Google Scholar 

  • Ritter, K., G. Bornmann U. A. Loeser: Allgemeinstoffwechsel und Trijodthyronin. Klin. Wschr. 1955, 743.

    Google Scholar 

  • Robbins, J., and J. E. Rall: Zone electrophoresis in filter paper of serum I131 after radio-iodide administration. Proc. Soc. Exper. Biol. a. Med. 81, 530 (1952).

    CAS  Google Scholar 

  • Robertis, E. De: Cytological and cytochemical bases of thyroid function. Ann. N. Y. Acad. Sci. 50, 317 (1949).

    Google Scholar 

  • Robertson, J. S., and J. T. Godwin: Calculation of radioactive iodine beta radiation dose to the bone marrow. Brit. J. Radiol. 27, 241 (1954).

    CAS  PubMed  Google Scholar 

  • Roche, J., S. Lissitzky Et R. Michel: Sur la triiodothyronine, produit intermédiaire de la transformation de la diiodothyronine en thyroxine. C. r. Acad. Sci. (Paris) 234, 997 (1952).

    CAS  Google Scholar 

  • Rotblat, J., and G. M. Owen: The biological half-life of I131 in thyroid carcinoma. Proc. Radioisotope Conf. 1, 68 (1954).

    Google Scholar 

  • Ruedemann, A. D., and K. E. Corrigan: Glandular type exophthalmos methods of treatment, including radioactive iodine. Trans. Amer. Ophthalm. Soc. 51, 333 (1954).

    Google Scholar 

  • Ruegamer, W. R.: The kinetics of I131 metabolism in the dog and human. Arch, of Biochem. 47, 119 (1953).

    CAS  Google Scholar 

  • Rugh, R., and E. Booth: Modification of maternal and fetal effects of radioiodine by pre-treatment of the mother. J. of Pediatr. 44, 516 (1954).

    CAS  Google Scholar 

  • Salter, W. T., M. De Visscher, G. B. Mcadams and I. Rosenblum: Changes in blood iodine fractions and radioactivity under therapy. J. Clin. Endocrin. 11, 1512 (1951).

    CAS  Google Scholar 

  • Sauter, H.: Der isolierte “Basedow”-Exophthalmus. Dtsch. med. Wschr. 1950, 1614.

    Google Scholar 

  • Sauter, H.: Weitere Erfahrungen mit der Hypophysenbestrahlung beim malignen Exophthalmus. Dtsch. med. Wschr. 1952, 1388.

    Google Scholar 

  • Sauter, H.: Die Stellung des endokrinen Exophthalmus innerhalb des Hypophysen-Schilddrüsensystems. Dtsch. med. Wschr. 1956, 761.

    Google Scholar 

  • Scherf, D.: Totale Thyreoidektomie bei Herzkrankheiten. Med. Klin. 1987, 1126.

    Google Scholar 

  • Schiff, L., C. D. Stevens, W. E. Molle, H. Steinberg, C. W. Kumpe and P. Stewart: Gastric (and salivary) excretion of radioiodine in man. J. Nat. Cancer Inst. 7, 349 (1947).

    CAS  PubMed  Google Scholar 

  • Schuchter, A., U. W. Bartsch: Über die Beeinflussung der Schilddrüsenfunktion durch Tumoren im Bereich der Sella und des Zwischenhirns. Ärztl. Wschr. 1952, 939.

    Google Scholar 

  • Schultz, A. L., and W. E. Jacobson: The effect of propylthiouracil on the thyroid uptake of I131 and the plasma conversion ratio in hyperthyroidism. J. Clin. Endocrin. 12, 1205 (1952).

    CAS  Google Scholar 

  • Schultz, A. L., S. Sandhaus, H. L. Demorest and L. Zieve: Clinical value of the plasma butanol-extractable (Thyroxine) I131 in the diagnosis of hyperthyroidism and myxedema. Clin. Endocrin. 14, 1062 (1954).

    CAS  Google Scholar 

  • Scott, W. G., W. B. Seaman, C. Macbryde, L. Gottlieb, W. H. Daughaday and B. J. Sweeney: Observations and results in the treatment of hyperthyroidism with radioactive iodine (I131). Amer. J. Roentgenol. 66, 171 (1951).

    CAS  Google Scholar 

  • Searle, H. H., O. Davies and S. Lindsay: Metastatic carcinoma of thyroid gland as initial manifestation of disease. Calif. Med. 76, 62 (1952).

    Google Scholar 

  • Seed, L., and T. Fields: Treatment of toxic goiter with radioactive iodine. Springfield, 111.: Ch. C. Thomas 1953.

    Google Scholar 

  • Seed, L., and B. Jaffe: Results of treatment of toxic goiter with radioactive iodine. J. Clin. Endocrin. 13, 107 (1953).

    CAS  Google Scholar 

  • Seed, L., and B. Jaffe: Comparison of the tracer dose and the therapeutic dose of I131 as to thyroid uptake, effective half life, and roentgen dosage. Radiology 63, 551 (1954).

    CAS  PubMed  Google Scholar 

  • Seidlin, S. M.: Twelve cases of metastatic carcinoma of the thyroid studied with radioactive iodine. Proc. for Study of Internal Secretion, June 6–7 (1947).

    Google Scholar 

  • Seidlin, S. M.: Clinical methods and results of radioiodine therapy in metastatic cancer. Brookhaven Conf. Report BNL-C-5, 106 (1948).

    Google Scholar 

  • Seidlin, S. M.: Radioiodine as a diagnostic and therapeutic tool in clinical medicine. Rec. Progr. in Hormone Res. 4, 483 (1949).

    Google Scholar 

  • Seidlin, S. M.: Radioiodine in the treatment of metabolic thyroid carcinoma. Med. Clin. N. Amer. 1952, 663–680

    Google Scholar 

  • Seidlin, S. M., and L. D. Marinelli: Therapeutic effect of radioactive iodine on adenocarcinoma of the thyroid with functioning metastases. Bull. N. Y. Acad. Med. 21, 440 (1945).

    Google Scholar 

  • Seidlin, S. M., and E. Oshry: Radioactive iodine therapy: Effect on functioning metastases of adenocarcinoma of the thyroid. J. Amer. Med. Assoc. 132, 838 (1946).

    CAS  Google Scholar 

  • Seidlin, S. M., E. Oshry, B. S. Yalow and A. A. Yalow: Spontaneous and experimentally induced uptake of radioactive iodine in metastases from thyroid carcinoma. J. Clin. Endocrin. 8, 423 (1948).

    CAS  Google Scholar 

  • Seidlin, S. M., J. Rossman, E. Oshry and E. Siegel: Radioiodine therapy of metastases from carcinoma of the thyroid (A six year progress report). J. Clin. Endocrin. 9, 1122 (1949).

    CAS  Google Scholar 

  • Seidlin, S. M., A. A. Yalow and E. Siegel: Irradiation produced rise in blood radioiodine concentration following ingested therapeutic dose for metastatic thyroid carcinoma. Proc. Soc. Exper. Biol. a. Med. 76, 711 (1951).

    CAS  Google Scholar 

  • Seidlin, S. M., A. A. Yalow and E. Siegel: Blood radiation dose during radioiodine therapy of metastatic thyroid carcinoma. Radiology 63, 797 (1954).

    CAS  PubMed  Google Scholar 

  • Shapiro, M. R.: Morphologic changes in the thyroid gland following radioiodine therapy. Ann. West. Med. Surg. 4, 274 (1950).

    CAS  PubMed  Google Scholar 

  • Shellabarger, C. J., and J. T. Godwin: Studies on the thyroidal uptake of Astatine in the rat. J. Clin. Endocrin. 14, 1149 (1954).

    CAS  Google Scholar 

  • Shipley, R. A., and F. H. Macintyre: Effect of stress, TSH and ACTH on the level of serum hormonal I131. J. Clin. Endocrin. 14, 309 (1954).

    CAS  Google Scholar 

  • Shipley, R. A., I. P. Storaasli, H. L. Friedell and A. M. Potts: I131 in the diagnosis and treatment of hyperthyroidism. Amer. J. Roentgenol. 64, 576 (1950).

    CAS  Google Scholar 

  • Siedek, H.: Totale Thyreoidektomie bei Herzkranken. Erg. inn. Med. 59, 1 (1940).

    Google Scholar 

  • Silver, S., M. H. Fieber and S. B. Yohalem: Blood levels after tracer doses of radioactive iodine in the diagnosis of thyroid disorders. Amer. J. Med. 13, 725 (1952).

    CAS  PubMed  Google Scholar 

  • Skanse, B. N.: Radioactive iodine: Its use in studying the urinary excretion of iodine by humans in various states of thyroid function. Acta med. scand. 131, 251 (1948).

    CAS  PubMed  Google Scholar 

  • Skanse, B. N.: Radioactive iodine in the diagnosis of thyreoid disease. Acta med. scand. (Stockh.) 235, 1 (1949).

    Google Scholar 

  • Soffer, L. J., J. L. Gabrilove and J. W. Jailer: Role of adrenal in uptake of I131 by thyroid following parenteral administration of epinephrine. Proc. Soc. Exper. Biol. a. Med. 71, 117 (1949).

    CAS  Google Scholar 

  • Soliman, F. A., and E. P. Reineke: Changes in uptake of radioactive iodine by the thyroid of the rat during the estrous cycle. Amer. J. Physiol. 178, 89 (1954).

    CAS  PubMed  Google Scholar 

  • Soliman, F. A., and E. P. Reineke: Cyclic variation in thyroid function of female mice as assessed by radioactive iodine. J. of Endocrin. 10, 305 (1954).

    CAS  Google Scholar 

  • Soley, M. H., and N. Foreman: Radioiodine therapy in Graves’ disease (A review). J. Clin. Invest, 28, 1367 (1949).

    CAS  PubMed  Google Scholar 

  • Soley, M. H., and E. R. Miller: Treatment of Graves’ disease with radioactive iodine. Med. Clin. N. Amer. 32, 3 (1948).

    CAS  PubMed  Google Scholar 

  • Soley, M. H., and N. Foreman: Graves’ disease: Treatment with radioiodine (I131). J. Clin. Endocrin. 9, 29 (1949).

    CAS  Google Scholar 

  • Sorrentino, J., B. Roswit and R. Yalow: Thyroid carcinoma with multiple metastases and pathological fracture-successfully treated with radioiodine. Report of a case. Radiology 57, 729 (1951).

    Google Scholar 

  • Specht, N. W., F. K. Bauer and R. M. Adams: Thyroid carcinoma. Visualization of a distant osseus metastasis by Scintiscanner, observations during I131 therapv. Amer. J. Med. 14, 766 (1953).

    CAS  PubMed  Google Scholar 

  • Stanbury, J. B., G. L. Brownell, J. Barzelatto, J. Correa, J. Maisterrena, J. Cortazar and J. Rodriguez-Soto: The metabolic fate of I131 after large therapeutic doses in patients with metastatic carcinoma of the thyroid. J. Clin. Endocrin. 12, 1480 (1952).

    CAS  Google Scholar 

  • Stanbury, J. B., D. S. Riggs, H. Perinetti, E. Del Castillo, I. Itoiz, A. Houssay and E. Trucco: The iodine-deficient human thyroid gland. A preliminary report. J. Clin. Endocrin. 12, 191 (1952).

    CAS  Google Scholar 

  • Stanbury, J. B., and J. B. Wyngaarden: Effect of Perchlorate on the human thyroid gland. Metabolism 1, 533 (1952).

    CAS  PubMed  Google Scholar 

  • Stang, L. G., W. D. Tucker, H. O. Banks, R. F. Doering and T. H. Mills: Production of iodine-132. Nucleonics 12, 22 (1954).

    CAS  Google Scholar 

  • Stanley, M. M., and E. B. Astwood: Determination of the relative activities of antithyroid compounds in man using radioactive iodine. Endocrinology (Springfield, 111.) 41, 66 (1947).

    CAS  Google Scholar 

  • Stanley, M. M., and E. B. Astwood: The accumulation of radioactive iodide by the thyroid gland in normal and thyrotoxic subjects and the effect of thiocyanate on its discharge. Endocrinology (Springfield, 111.) 42, 107 (1948).

    CAS  Google Scholar 

  • Stanley, M. M., and E. B. Astwood: The response of the thyroid gland in normal administration of thyrotropin, as shown by studies with I131. Endocrinology (Springfield, 111.) 44, 49 (1949).

    CAS  Google Scholar 

  • Starr, P., and R. Liebhold-Schueck: Theory of thyroid hormone action. Conclusions derived from differences in effect of sodium 1-thyroxine, sodium d-thyroxine, triijdo-thyronine and potassium iodide on uptake of radioactive iodine by thyroid gland of normal human subjects. Arch. Int. Med. 92, 880 (1953).

    CAS  Google Scholar 

  • Starr, P., and R. W. Rawson: A graphic representation of thyroid response to stimulation by thyrotropic hormone. Proc. Soc. Exper. Biol. a. Med. 35, 603 (1937).

    Google Scholar 

  • Starr, P., and R. Roskelley: A comparison of the effects of cold and thyrotropic hormone on the thyroid gland. Amer. J. Physiol. 130, 549 (1940).

    CAS  Google Scholar 

  • Steinitz, K.: Fortschritte in der Diagnose und Therapie der Erkrankungen der Schilddrüse. Klin. Wschr. 1956, 265.

    Google Scholar 

  • Sterling, K., J. C. Lashof and E. B. Man: Disappearance from serum of I131-labeled 1-thyr-oxine and 1-triiodothyronine in euthyroid subjects. J. Clin. Invest. 33, 1031 (1954).

    CAS  PubMed  Google Scholar 

  • Stirrett, R. L., D. W. Petit and P. Starr: Therapeutic studies in hyperthyroidism: Methyl-thiouracil. J. Clin. Endocrin. 12, 719 (1952).

    CAS  Google Scholar 

  • Storaasli, J. P., S. Rosenberg and H. L. Friedell: Effect of food and water on thyroid uptake of radio-iodine (I131). Proc. Soc. Exper. Biol. a. Med. 83, 748 (1953).

    CAS  Google Scholar 

  • Strauss, E., J. Hiller U. A. Jakob: Zur Statistik des Radiojodtestes. Verh. dtsch. Ges. Verdauungskrkh. 1954, 181.

    Google Scholar 

  • Stump, W.: Funktionelle Störungen der Schilddrüse bei endemischer Struma, untersucht mittels radioaktiven Jods ( J131 ). Habilitationsschrift, Freiburg 1954.

    Google Scholar 

  • Sturgeon, C. T., F. E. Davis, B. Catz, D. Petit and P. Starr: Treatment of thyroid cancer metastases with TSH and I131 during thyroid hormone medication. J. Clin. Endocrin. 13, 1391 (1953).

    CAS  Google Scholar 

  • Sturm, A., U. W. Wernitz: Hormonjod im Gehirn. Klin. Wschr. 1956, 93.

    Google Scholar 

  • Szilagyi, D. E., R. Mcclure, T. H. Connell, J. H. L. Wtatson and L. E. Preuss: Radio-iodine (I131) tracer studies after total thyreoidectomy. Ann. Surg. 134, 546 (1951).

    CAS  PubMed  Google Scholar 

  • Taurog, A., I. L. Chaikoff and D. D. Feller: The mechanism of iodine concentration by the thyroid gland: Its non-organic iodine-binding capacity in the normal and propyl-thiouracil-treated rat. J. of Biol. Chem. 171, 189 (1947).

    CAS  Google Scholar 

  • Taylor, S., and F. X. Stewart: Distribution of Radio-iodine in human thyroid gland. Lancet 1951 II, 232.

    Google Scholar 

  • Thode, G. H., C. H. Jaimet and S. Kirkwood: Studies and diagnostic tests of salivary and thyroid gland function with radioiodine. Proc. Radioisotope Conf. 1, 55 (1954).

    Google Scholar 

  • Thode, G. H., C. H. Jaimet and S. Kirkwood: New England J. Med. 251, 129 (1954).

    CAS  Google Scholar 

  • Thompson, W. O.: The present status of the treatment of toxic goiter. J. Clin. Endocrin. 12, 130 (1952).

    CAS  Google Scholar 

  • Tighe, W. I.: Temporary hypoparathyroidism following radioactive iodine treatment for thyreotoxicosis. J. Clin. Endocrin. 12, 1220 (1952).

    CAS  Google Scholar 

  • Tishkoff, G. H., R. Bennett, V. Bennett and L. L. Miller: Radioiodine and paper chromatography technique in the study of thyroid metabolism. Science (Lancaster, Pa.) 110, 452 (1949).

    CAS  Google Scholar 

  • Trippel, O. H., G. E. Sheline, R. H. Moe and D. E. Clark: Clinical application of radioactive iodine in diseases of the thyroid. Med. Clin. N. Amer. 35, 37 (1951).

    CAS  PubMed  Google Scholar 

  • Trunnell, J. B., B. J. Duffy, J. T. Godwin, W. Peacock, L. Kirschner and R. Hill: The distribution of radioactive iodine in human tissues-Necropsy study in nine patients. J. Clin. Endocrin. 10, 1007 (1950).

    CAS  Google Scholar 

  • Trunnell, J. B., L. D. Marinelli, B. L. Duffy, R. Hill, W. Peacock and R. W. Rawson: The treatment of metastatic thyroid cancer with radioactive iodine: Credits and debits. J. Clin. Endocrin. 9, 1138 (1949).

    CAS  Google Scholar 

  • Trunnell, J. B., and P. Wade: Factors governing the development of the chick embryo thyroid. II. Chronology of iodinated compounds studied by chromatographic analysis. J. Clin. Endocrin. 15, 107 (1955).

    CAS  Google Scholar 

  • Uotila, U. U.: The regulation of thyrotropic function by thyroxin after pituitary stalk section. Endocrinology (Springfield, 111.) 26, 129 (1940).

    CAS  Google Scholar 

  • Vanderlaan, J. E., and W. P. Vanderlaan: The iodide concentrating mechanism of the rat thyroid and its inhibition by thiocyanate. Endocrinology (Springfield, 111.) 40, 403 (1947).

    CAS  Google Scholar 

  • Vanderlaan, W. P., and A. Bissell: Effect of propylthiouracil and potassium thiocyanate on the uptake of iodine by the thyroid gland of the rat. Endocrinology (Springfield, 111.) 39. 157 (1946).

    CAS  Google Scholar 

  • Vanderlaan, W. P., and M. A. Greer: Some effects of the hypophysis on iodine metabolism by the thyroid gland of the rat. Endocrinology (Springfield, 111.) 47, 36 (1950).

    CAS  Google Scholar 

  • Vannotti, A., Et M. Closuit: Relations fonctionelles entre la thyroide et le système endocrinien étudiées à l’aide du test au radio-iode. Bull. Schweiz. Akad. Med. Wiss. 8, 476 (1952).

    CAS  PubMed  Google Scholar 

  • Verzár, F., and Y. Vidovic: The action of thyrotrophs hormone and cortisone on the uptake of I131 by the thyroid gland. J. of Endocrin. 8, 321 (1952).

    Google Scholar 

  • Verzár, F., E. Sailer and V. Vidovic: Changes in thyroid activity at law atmospheric pressures and at high altitudes, as tested with I131. J. of Endocrin. 8, 308 (1952).

    Google Scholar 

  • Vetter, H.: Die Diagnostik der Schilddrüsenerkrankungen mit radioaktivem Jod. Erg. inn. Med. 6, 695–790 (1955).

    CAS  Google Scholar 

  • Visscher, M. De, G. B. Mcadams Et W. T. Salter: Emploi de l’iode radioactif dans la détermination de l’activité sécrétoire thyroidienne. Ann. d’Endocrin. 12, 573 (1951).

    Google Scholar 

  • Warren, S.: A classification of tumors of the thyroid. Amer. J. Roentgenol. 46, 447 (1941).

    Google Scholar 

  • Wayne. E. J.: The treatment of thyrotoxicosis with radioactive iodine. Proc. Roy. Soc. Med. 45, 338 (1952).

    PubMed  Google Scholar 

  • Wayne. E. J.: The diagnosis of thjTotoxicosis. Brit. Med. J. 19541, 411.

    Google Scholar 

  • Wayne. E. J., A. G. Macgregor and G. W. Blomfield: Treatment of thyrotoxicosis with I131. Brit. Med. Bull. 8, 148 (1952).

    Google Scholar 

  • Wegelin, C.: Die Schilddrüse, in: Handbuch der speziellen pathologischen Anatomie und Histologie. Bd. 8, pp. 175–176. Berlin: Julius Springer 1926.

    Google Scholar 

  • Wegelin, C.: Die pathologische Anatomie der Struma maligna und der Kretinenschilddrüse. Ber. Internat. Kropfkonf. in Bern 1927. Bern: H. Huber 1928.

    Google Scholar 

  • Weinbren, M.: Carcinom of the thyroid in children. S. Afric. J. Clin. Sci. 5, 179 (1954).

    Google Scholar 

  • Weissbecker, L.: Krankheiten des endokrinen Systems und der Stoffwechselfunktion. In Lehrbuch der inneren Medizin. Berlin-Göttingen-Heidelberg: Springer-Verlag 1955.

    Google Scholar 

  • Werner, S. C.: Results in treatment of hyperthyroidism writh radioiodine I131. Med. Clin. X. Amer. 1952, 623.

    Google Scholar 

  • Werner, S. C., L. D. Goodwin and E. H. Quimby: The tracer technique wdth radioactive iodine, I131, as a potential substitute for the basal metabolic rate determination in routine clinical practice. J. Clin. Endocrin. 9, 664 (1949).

    Google Scholar 

  • Werner, S. C., and C. Schmidt: Some results from use of radioactive iodine, I131, in diagnosis and treatment of toxic goiter. Amer. J. Roentgenol. 63, 889 (1950).

    CAS  Google Scholar 

  • Werner, S. C., H. B. Hamilton, E. Leifer and L. D. Goodwin: An appraisal of the radioiodine tracer technic as a clinical procedure in the diagnosis of thyroid disorders. Uptake measurement directly over the gland and a note on the use of thyrotropin (TSH). J. Clin. Endocrin. 10, 1054 (1950).

    CAS  Google Scholar 

  • Werner, S. C., and M. R. Nemeth: Therapeutic effects from repeated diagnostic doses of I131 in adult and juvenile hyperthyroidism. J. Clin. Endocrin. 12, 1349 (1952).

    CAS  Google Scholar 

  • Werner, S. C., E. H. Quimby and C. Schmidt: Clinical experience in diagnosis and treatment of thyroid disorders with radioactive iodine. Radiology 51, 564 (1948).

    CAS  PubMed  Google Scholar 

  • Werner, S. C., E. H. Quimby and C. Schmidt: The use of tracer doses of radioactive iodine, I131, in the study of normal and disordered thyroid function in man. J. Clin. Endocrin. 9, 342 (1949).

    CAS  Google Scholar 

  • Werner, S. C., E. H. Quimby and C. Schmidt: Radioactive iodine I131 in the treatment of hyperthyroidism. Amer. J. Med. 7, 731 (1949).

    CAS  PubMed  Google Scholar 

  • White, W. E., and W. A. Reilly: Chromatographic changes in plasma I131 during the treatment of Graves’ and cardiac diseases correlated with clinical course. J. Labor, a. Clin. Med. 43, 553 (1954).

    CAS  Google Scholar 

  • Wichmann, F. W., U. P. Schmidt: Über die Beeinflussung der Luftröhre bei Strumen und die Bedeutung der röntgenologischen Voruntersuchungen für die Strumektomie. Chirurg 21. 280 (1950).

    CAS  PubMed  Google Scholar 

  • Williams, R. H., H. Jaffe and J. A. Taylor: Effect of halides thiocyanate and propylthiouracil upon the distribution of radioiodine in the thyroid gland, blood and urine. Amer. J. Med. Sci. 219, 7 (1950).

    CAS  PubMed  Google Scholar 

  • Williams, R. H., G. T. Towery, W. F. Rogers and R. Tagnon: Factors influencing the effectiveness of radioiodotherapeusis. Amer. J. Med. 7, 718 (1949).

    CAS  PubMed  Google Scholar 

  • Williams, R. H., B. T. Towery, H. Jaffe, W. F. Rogers and R. Tagnon: Radioiodotherapeusis. Amer. J. Med. 7, 702 (1949).

    CAS  PubMed  Google Scholar 

  • Wing, E. S., and S. P. Asper: Observations on the use of propylthiouracil in hyperthyroidism with especial reference to long term treatment. Bull. Johns Hopkins Hosp. 90, 201 (1952).

    CAS  PubMed  Google Scholar 

  • Winkler, C.: Aussichten der Behandlung maligner Strumen mit radioaktivem Jod. Dtsch. med. Wschr. 1950, 1438.

    Google Scholar 

  • Winkler, C.: Radioaktives Jod zur Diagnose und Therapie von Schilddrusenerkrankungen. Strahlen-ther. 85, 126 (1951).

    CAS  Google Scholar 

  • Winzler, R. J., and S. R. Notrica: Association of thyroxine with plasmaproteins. Federat. Proc. 11, 312 (1952).

    Google Scholar 

  • Wolff, J., I. L. Chaikoff, A. Taurog and L. Rubin: The disturbance in iodine metabolism produced by thiocyanate: The mechanism of its goitrogenic action with radioactive iodine as indicator. Endocrinology (Springfield, 111.) 39, 140 (1946).

    CAS  Google Scholar 

  • Wollman, S. H., and R. D. Scow: The effect of propylthiouracil on radioiodide concentrating, by the thyroid gland in normal and hypophysectomized mice. Endocrinology (Springfield, 111.) 53, 332 (1953).

    CAS  Google Scholar 

  • Wyngaarden, J. B., J. B. Stanbury and B. Rapp: The effects of iodide, perchlorate, thiocyanate, and nitrate administration upon the iodide concentrating mechanism of the rat thyroid. Endocrinology (Springfield, 111.) 52, 568 (1953).

    CAS  Google Scholar 

  • Wyngaarden, J. B., and C. H. Du Toit: On the mechanism of iodide accumulation by the thyroid gland. J. Clin. Endocrin. 11, 1259 (1951).

    CAS  Google Scholar 

  • Wyngaarden, J. B., B. M. Wright U. P. Ways: The effect of certain anions upon the accumulating and reten-tion of iodide by the thyroid gland. Endocrinology (Springfield, 111.) 50, 537 (1952).

    CAS  Google Scholar 

  • Zieve, L., B. Skanse and A. L. Schultz: Comparative value of the basal metabolic rate, chemical protein-bound iodine, and radioactive excretion or uptake in the diagnosis of borderline hyperthyroidism, when used individually or in combination. J. Labor, a. Clin. Med. 45, 281 (1955).

    CAS  Google Scholar 

  • Zingg, W., and W. F. Perry: Influence of adrenal and gonadal steroids on the uptake of iodine by the thyroid gland. J. Clin. Endocrin. 13, 712 (1953).

    CAS  Google Scholar 

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Keiderling, W. (1957). Therapie der Schilddrüse mit Radiojod. In: Heilmeyer, L., Schoen, R., Glanzmann, E., De Rudder, B. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde. Ergebnisse der Inneren Medizin und Kinderheilkunde, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-94687-5_6

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