Skip to main content

Die Diagnostik der Schilddrüsen-Erkrankungen mit radioaktivem Jod

  • Conference paper
Ergebnisse der Inneren Medizin und Kinderheilkunde

Part of the book series: Ergebnisse der Inneren Medizin und Kinderheilkunde ((KINDERHEILK. NF,volume 6))

Zusammenfassung

Rund fünfzehn Jahre nach den ersten tastenden Versuchen hinsichtlich der diagnostischen und therapeutischen Anwendungsmöglichkeiten der künstlich radioaktiven Isotope ist die Diagnostik der Schilddrüsenerkrankungen mit Hilfe des radioaktiven Jods eine Standardmethode der meisten führenden Kliniken der Welt geworden. Es besteht kein Zweifel, daß der Bedarf nach einer Verfeinerung und Vervollkommnung unserer technischen Hilfsmittel zur objektiven Feststellung krankhafter Veränderungen dieses Organs — besonders hinsichtlich seiner Funktion — vorhanden war und auch heute noch ist. Dieser Bedarf ist begründet in den Schwierigkeiten, denen sich der Kliniker in einem beträchtlichen Prozentsatz der Fälle gegenübersieht, wenn es gilt, die oft spärlich vorhandenen und manchmal vieldeutigen klinischen Symptome zur bestimmenden Grundlage seines therapeutischen Handelns zu verarbeiten. Die laboratoriumstechnischen Hilfsmittel wie Grundumsatz, Serumcholesterin, Elektrokardiogramm und andere versagen nicht selten, da sie nicht absolut spezifisch und von vielerlei, außerhalb des eigentlichen Geschehens liegenden Faktoren beeinflußt sind. Nur die chemische Bestimmung des eiweißgebundenen Jods im Plasma darf eine hohe Spezifität für sich beanspruchen, doch ist ihre Durchführung schwierig und zeitraubend und daher für die klinische Routine wenig geeignet.

Aus der II. Medizinischen Universitätsklinik in Wien (Vorstand: Prof. Dr. K. Fellinger)

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Ackermann, P. G., and K. I Versen: Radio-iodine excretion in the aged. J. of Gerontol. 8, 458 (1953).

    CAS  Google Scholar 

  • Albert, A.: Thyroid gland. Annual Rev. Physiol. 14, 481 (1952).

    CAS  Google Scholar 

  • Albert, A., E. Ford and N. Lorenz: Effects of altered thyroid function upon the metabolism of endogenously labeled thyroid hormone. Endocrinology (Springfield, Ill.) 53, 50 (1953).

    CAS  Google Scholar 

  • Albert, A. and F. R. Keating, Jr.: [1] Metabolic studies with I131-labeled thyroid compounds. Comparison of the distribution and fate of radioactive d-1-thyroxine after oral and intravenous administration in the human. J. Clin. Endocrin. 9, 1406 (1949).

    CAS  Google Scholar 

  • Albert, A. and F. R. Keating, Jr.: [2] The rôle of the gastrointestinal tract, including the liver, in the metabolism of radiothyroxine. Endocrinology (Springfield, Ill.) 51, 427 (1952).

    CAS  Google Scholar 

  • Albert, A. and N. Lorenz: Effect of hypophysectomy on the intrathyroid metabolism of I131. Proc. Soc. Exper. Biol. a. Med. 77, 204 (1951).

    CAS  Google Scholar 

  • Albert, A., J. E. Rall, F. R. Keating, Jr., M. H. Power and M. M. D. Williams: The behavior of labeled thyroglobulin and labeled thyroxine in patients with myxedema. J. Clin. Endocrin. 9, 1392 (1949).

    CAS  Google Scholar 

  • Albert, A., R. W. Rawson, P.Merrill, B. Lennon and C. Riddell: Reversible inactivation of thyrotropic hormone by elemental iodine. I. The action of iodine. J. of Biol. Chem. 166, 637 (1946).

    CAS  Google Scholar 

  • Albert, A., R. W. Rawson, C. Riddell, P. Merrill and B. Lennon: In vivo augmentation of thyrotropic hormone and partial reactivation of iodinated (inactive) thyrotropic hormone extract by goitrogens. Endocrinology (Springfield, Ill.) 40, 361 (1947).

    CAS  Google Scholar 

  • Albert, A. and A. Tenney: Effect of iodide, thiouracil and thyroxine on the disappearance of thyroidal I131. Proc. Soc. Exper. Biol. a. Med. 77, 202 (1951).

    CAS  Google Scholar 

  • Albright, E. C., F. G. Larson and W. P. Deiss: [1] Observations on the capacity of serum alpha globuline to bind thyroxine in vitro. J. Clin. Invest. 33, 914 (1954).

    Google Scholar 

  • Albright, E. C., F. G. Larson and W. P. Deiss: [2] Thyroxine binding capacity of serum alpha globulin in hypothyroid, euthyroid and hyperthyroid subjects. J. Clin. Invest. 34, 44 (1955).

    PubMed  CAS  Google Scholar 

  • Albright, E. C. and W. S. Middleton: The uptake of radioactive iodine by the thyroid gland of leucemic patients. Blood 5, 764 (1950).

    PubMed  CAS  Google Scholar 

  • Allen, H. C. Jr., F. J. Kelly and J. A. Greene: Observations on the nodular thyroid gland with the gammagraph. J. Clin. Endocrin. 12, 1356 (1952).

    Google Scholar 

  • Allen, H. C. Jr., R. L. Libby and B. Cassen: The scintillation counter in clinical studies of human thyroid physiology using I131. J. Clin. Endocrin. 11, 492 (1951).

    Google Scholar 

  • Allen, H. C. Jr., J. R. Risser and J. A. Greene: Improvements in outlining of thyroid and localization of brain tumors by the application of sodium iodide gamma-ray spectrometry techniques. A. E. R. E. Harwell Radioisotope Conference 1954. Vol. I., S. 76. London: Butterworths 1954.

    Google Scholar 

  • andrews, G. A., R. M. Kniseley, R. R. Bigelow, S. W. Root and M. Brucer: Pathologic changes in normal human thyroid tissue following large doses of I131. Amer. J. Med. 16, 372 (1954).

    PubMed  CAS  Google Scholar 

  • Anger, H. O.: Scintillation counters for the measurement of radioactive samples. A. E. C. Report UCRL 886, August 1950 und Februar 1951.

    Google Scholar 

  • Ansell, G., and H. Miller: Influence of iodine on the release of thyroid hormone in thyrotoxicosis. Lancet 1952/11, 5.

    Google Scholar 

  • Ansell, G. and J. Rotblat: Radioactive iodine as a diagnostic aid for intrathoracic goitre. Brit. J. Radiol. 21, 552 (1948).

    PubMed  CAS  Google Scholar 

  • Ariel, I., W. F. Bale, V. Downing, H. C. Hodge, W. Mann, S. N. Vanvoorhis, S. L. Warren and H. C. Wilson: The distribution of radioactive isotopes of iodine in normal rabbits. Amer. J. Physiol. 132, 346 (1941).

    CAS  Google Scholar 

  • Arnott, D. G., E. W. Emery, R. Fraser and Q. J. G. Hobson: Urinary excretion of radioactive iodine as a diagnostic test in thyroid disease. Lancet 1949/11, 460.

    Google Scholar 

  • Arsdel, P. Van, Jr., J. R. Hogness, R.H.Williams and N. Elgee: Comparative distribution and fate of I131 labeled thyroxine and triiodothyronine. Endocrinology (Springfield, Ill.) 55, 332 (1954).

    Google Scholar 

  • Asper, S. P., H. A. Selenkow and C. A. Plamondon: A comparison of the metabolic activities of 3:5:3M-triiodothyronine and 1-thyroxine in myxedema. Bull. Johns Hopkins Hosp. 93, 164 (1953).

    PubMed  CAS  Google Scholar 

  • Astwood, E. B.: [1] The chemical nature of compounds which inhibit the function of the thyroid gland. J. Pharmacol, a. Exper. Ther. 78, 79 (1943).

    CAS  Google Scholar 

  • Astwood, E. B.: [2] Chemotherapy of hyperthyroidism. Harvey Lect. 40, 195 (1944/45).

    Google Scholar 

  • Astwood, E. B.: [3] Mechanisms of action of various antithyroid compounds. Ann. N. Y. Acad. Sci. 50, 419 (1949).

    PubMed  CAS  Google Scholar 

  • Astwood, E. B. and A. Bissell: Effect of thiouracil on the iodine content of the thyroid gland. Endocrinology (Springfield, Ill.) 34, 282 (1944).

    CAS  Google Scholar 

  • Astwood, E. B., A. Bissell and A. M. Hughes: Further studies on the chemical nature of compounds which inhibit the function of the thyroid gland. Endocrinology (Springfield, Ill.) 37, 456 (1945).

    CAS  Google Scholar 

  • Astwood, E. B., J.Sullivan, A. Bissell and R. Tyslowitz: Action of certain sulfonamides and of thiourea upon the functions of the thyroid gland of the rat. Endocrinology (Springfield,111.) 32, 210 (1943).

    CAS  Google Scholar 

  • Atkinson, J. B.: Factitial thyrotoxic crisis induced by dextro-amphetamine sulfate and thyroid. Ann. Int. Med. 40, 615 (1954).

    PubMed  CAS  Google Scholar 

  • Azerad, E., et C. Ravaud: Valeur respective du métabolisme de base et de l’épreuve de fixation de l’iode radio-actif dans l’exploration fonctionelle de la glande thyroide. Semaine Hôp. 1954, 1373.

    Google Scholar 

  • Bansi, H. W.: [1] Jod; in Künstliche radioaktive Isotope in Physiologie, Diagnostik und Therapie. Berlin-Göttingen-Heidelberg: Springer-Verlag 1953.

    Google Scholar 

  • Bansi, H. W.: [2] Krankheiten der Schilddrüse; in Handbuch der inneren Medizin, 4. Aufl., VII. Bd., 1. Teil. Berlin-Göttingen-Heidelberg: Springer-Verlag 1955.

    Google Scholar 

  • Bansi, H. W., J. Kracht, u. Kracht u. J. Meissner: Zur Entstehung des Morbus Basedow. Praktisch wichtige Ergebnisse experimenteller Arbeiten. Dtsch. med. Wschr. 1953, 256.

    Google Scholar 

  • Barkan, G., u. W. Leistner: Das Verhalten des Jods in den Körpersäften nach Verfütterung von Jodalkalien und Jodeiweiß. Klin. Wschr. 1929, 117.

    Google Scholar 

  • Barker, M. H.: The blood cyanates in the treatment of hvpertension. J. Amer. Med. Assoc. 106, 762 (1936).

    CAS  Google Scholar 

  • Barker, S. B.: Mechanism of action of the thyroid hormone. Physiologic. Rev. 31, 205 (1951).

    CAS  Google Scholar 

  • Barrett, T. F., H. Peck, F. K. Bauer, R. L. Libby and S. R. Jarrett: Evaluation of a thyroid panel. Practical application of scintillation counter in diagnosis of diseases of the thyroid. J. Amer. Med. Assoc. 152, 1414 (1953).

    CAS  Google Scholar 

  • Barry, M. C., and A. E. Pugh: Serum concentrations of radioiodine in diagnostic tracer studies. J. Clin. Endocrin. 13, 980 (1953).

    CAS  Google Scholar 

  • Bartels, E. C., and J. T. Marrow: Factitial hyperthvroidism. Report of a case. Lahey Clin. Bull. 8, 208 (1954).

    CAS  Google Scholar 

  • Bassett, A. M., A. H. Coons and W. T. Salter: Protein-bound iodine in blood, naturally occuring iodine fractions and their chemical behavior. Amer J. Med. Sci. 202, 516 (1941).

    CAS  Google Scholar 

  • Bauer, F. K.: I131 uptake in treated hyperthyroidism. Amer. J. Med. Sci. 223, 495 (1952).

    PubMed  CAS  Google Scholar 

  • Bauer, F. K., W. E. Goodwin, T. F. Barrett, R. L. Libby and B. Cassen: Scintigrams of the thyroid gland. (The diagnosis of morphologic abnormalities with I131). Calif. Med. 77, 380 (1952).

    PubMed  CAS  Google Scholar 

  • Bauer, F. K., W. E. Goodwin, R. L. Libby and B. Cassen: Visual delineation of thyroid glands in vivo. J. Labor, a. Clin. Med. 39, 153 (1952).

    CAS  Google Scholar 

  • Becker, D. V., J. E. Rall, W. Peacock and R. W. Rawson: The effect of a thyrotrophs hormone preparation on the metabolism of radioiodine in euthyroid, hyperthvroid and acromegalic individuals. J. Clin. Invest. 32, 149 (1953).

    PubMed  CAS  Google Scholar 

  • Beierwaltes, W. H., I. Lampe, H. J. Gomberg and G. H. Lowrey: Radioiodine uptake curves in humans. III. The evaluation of radioiodine measurements made with the counter tube in apposition to the thyroid isthmus. Univ. Hosp. Bull. Ann Arbor 16, 2 (1950).

    Google Scholar 

  • Belcher, E. H., and H. D. Evans: A directional scintillation counter for clinical measurements. J. Scient. Instr. 28, 71 (1951).

    CAS  Google Scholar 

  • Benua, R. S., A.Albert and F.R.Keating, Jr.: The metabolism of radiothyroxine in exophthalmic goiter. J. Clin. Endocrin. 12, 1461 (1952).

    CAS  Google Scholar 

  • Benua, R. S. and B. M. Dobyns: Iodinated compounds in the serum, disappearance of radioactive iodine from the thyroid, and clinical response in patients treated with radioactive iodine. J. Clin. Endocrin. 15, 118 (1955).

    CAS  Google Scholar 

  • Berger, M., M. Dargent et R. Moret: Intérêt du radio-iode dans le diagnostic des affections thyroidiennes (Mesures externes de la radioactivité). J. Radiol. Electrol. 31, 540 (1950).

    CAS  Google Scholar 

  • Berger, M., P. Gutnet et R. Moret: L’apport des techniques au radio-iode dans l’étude physio- pathologique du goitre du jeune. Semaine Hôp. 1953, 1507.

    Google Scholar 

  • Berkson, J., F. R. Keating, Jr., M. H. Power and W. M. McConahey: Determination of renal clearance of radioiodine. J. Appl. Physiol. 2, 522 (1950).

    PubMed  CAS  Google Scholar 

  • Berson, S. A., andr. S. Yalow: [1] Quantitative aspects of iodine metabolism. The exchangeable organic iodine pool, and the rates of thyroidal secretion, peripheral degradation and fecal excretion of endogenously synthesized organically bound iodine. J. Clin. Invest. 33, 1533 (1954).

    PubMed  CAS  Google Scholar 

  • Berson, S. A., [2] The iodide trapping and binding functions of the thyroid. J. Clin. Invest. 34, 186 (1955).

    PubMed  CAS  Google Scholar 

  • Berson, S. A., R. S. Yalow, J. Sorrentino and B. Roswit: The determination of thyroidal and renal plasma I131 clearance rates as a routine diagnostic test for thyroid dvsfunction. J. Clin. Invest. 31, 141 (1952).

    PubMed  CAS  Google Scholar 

  • Billion, H.: Zum heutigen Stand des Radiojod-Testverfahrens. Strahlenther. Sonderb. 33, 104 (1955).

    Google Scholar 

  • Billion, H. u. P. Kühne: Der Wert verschiedener Radiojodtestverfahren für die Differentialdiagnostik von Schilddrüsenfunktionsstörungen. (Mit einem Beitrag zur aktiven Hyperplasie.) Z. klin. Med. 152, 411 (1954).

    PubMed  CAS  Google Scholar 

  • Billion, H., K. Oeff u. F. Klauer: Ergebnisse mit dem Radiojodtest der Schilddrüse. Ärztl. Wschr. 1951, 306.

    Google Scholar 

  • Blackburn, C. M., and F.R. Keating, Jr.: Comparative effectiveness of daily doses of 1-triiodothyronine or 1-thyroxine in the control of myxedema. J. Clin. Invest. 33, 918 (1954).

    Google Scholar 

  • Blackburn, C. M., F.R. Keating, Jr., and S.F.Haines: Radioiodine tracer studies in thiocyanate myxedema. J. Clin. Endocrin. 11, 1503 (1951).

    CAS  Google Scholar 

  • Blanco-Soler Y Ros, C., En. H. Vetter: El radioiodo-plasmatest en el diagnostico de las disfunciones tiroideas. Rev. Clin. Espan. 56, 96 (1955).

    Google Scholar 

  • Bloch-Michel, H.: L’exploration fonctionelle du corps thyroide. Ann. d’Endocrin. 14, 128 (1953).

    CAS  Google Scholar 

  • Blom, P. S., and J. Terpstra: High PBI131 concentrations in blood of patients with myxedema: preliminary report. J. Clin. Endocrin. 13, 989 (1953).

    CAS  Google Scholar 

  • Blondal, H.: A plasma I131 index for assessing thyroid activity. Brit. J. Radiol. 25, 260 (1952).

    PubMed  CAS  Google Scholar 

  • Bortin, M. M., and S. B. Yohalem: Thyrotoxicosis factitia masked as heart disease. Amer. Heart J. 89, 894 (1950).

    Google Scholar 

  • Bowman, K. M., E. R. Miller, M. E. Dailey, A. Simon and B. F. Mayer: Thyroid function in mental disease. A multiple test survey. J. Nerv. a. Ment. Dis. 112, 1404 (1950).

    Google Scholar 

  • Bradt, H., P. C. Gugelot, O. Huber, H. Medictts, P. Preiswerk and P. Scherrer: Sensivity of counter tubes with lead, brass and aluminum cathodes for gamma rays in energy range 0.1 to 3 MEV. Helvet. phys. Acta 19, 77 (1946).

    CAS  Google Scholar 

  • Brenner, O., A. B. Black and R. Gaddie: Estimation of the rate of thyroid hormone secretion in man. Clin. Sci. 13, 441 (1954).

    PubMed  CAS  Google Scholar 

  • Broser, L., and H. Kallmann: [1] Über die Anregung von Leuchtstoffen durch schnelle Korpuskularteilchen. Z. Naturforsch. 2A, 439 (1947).

    Google Scholar 

  • Broser, L., and H. Kallmann: [2] Über den Elementarprozeß der Lichtanregung in Leuchtstoffen durch -Teilchen, schnelle Elektronen und y-Quanten. Z. Naturforsch. 2A, 642 (1947).

    Google Scholar 

  • Brownell, G. L.: Analysis of techniques for the determination of thyroid function with radioiodine. J. Clin. Endocrin. 11, 1095 (1951).

    CAS  Google Scholar 

  • Brownell, G. L. and J. B. Stanbury: Instrumentation for thyroid measurement. J. Clin. Endocrin. 13, 210 (1953).

    CAS  Google Scholar 

  • Bruger, M., J. W. Hinton and W. G. Lough: The iodine content of blood, urine and saliva of normal persons in the New York city area. J. Labor a. Clin. Med. 26, 1942 (1941).

    Google Scholar 

  • Bruger, M. and S. Member: On the excretion of iodine in the saliva. Amer. J. Physiol. 139, 212 (1943).

    CAS  Google Scholar 

  • Bruner, H. D., and J. D. Perkinson, Jr.: A comparison of iodine-131 counting methods. Nucleonics 10, 57 (1952).

    CAS  Google Scholar 

  • Bullard, E. C.: British standard of radioactive iodine (131I). Nature (London) 170, 916 (1952).

    CAS  Google Scholar 

  • Burns, F. J., W. A. Fish, J. W. Hackett and F. C. Hickey: Radioactive decay and metabolic loss of iodine from normal thyroid. J. Appl. Physiol. 4, 15 (1951).

    PubMed  CAS  Google Scholar 

  • Burrows, B. A., T. Peters and J. F. Ross: The tissue utilization of endogenous thyroid hormone in human subjects. J. Clin. Invest. 33, 921 (1954).

    Google Scholar 

  • Burrows, B. A., J. F. Ross, E. S. Dell, D. E. Graham and D. F. Hammack: The thyroidal uptake of stable iodine compared with the serum concentration of protein-bound iodine in normal subjects and in patients with thyroid disease. J. Clin. Endocrin. 13, 1358 (1953).

    CAS  Google Scholar 

  • Cassen, B., L. Curtis and C. W. Reed: A sensitive directional gamma-ray detector. Nucleonics 6, 78 (1950).

    Google Scholar 

  • Castenfors, H., J. Ek u. I. G. Porje: Urrintsöndring och clearance av J131 vid olika kliniska tillstand. Nord. Med. 50, 1325 (1953).

    PubMed  CAS  Google Scholar 

  • Catz, B., I. El Rawi and E. Geiger: Increased I131 collection by the thyroid of the rat in acute starvation. Amer. J. Physiol. 172, 291 (1953).

    PubMed  CAS  Google Scholar 

  • Chagas, C., E. Derobertis and A. Conceiro: Penetration of radioactive iodine in the thyroid gland colloid. Texas Rep. Biol. a. Med. 3, 170 (1945).

    CAS  Google Scholar 

  • Chamovitz, D. L., M. H. Sleisenger and A. S. Freedberg: Measurement of the thyroid gland iodine-131-uptake andserum protein bound iodine-131. Amer. J.Med. 11, 255 (1951).

    Google Scholar 

  • Chapman, E. M., G. W. Corner, D. Robinson and R. D. Evans: The collection of radioactive iodine by the human fetal thyroid. J. Clin. Endocrin. 8, 717 (1948).

    CAS  Google Scholar 

  • Chapman, E. M., F. Maloof, J. Maisterrena and J. M. Martin: Ten years experience with radioactive iodide. J. Clin. Endocrin. 14, 45 (1954).

    CAS  Google Scholar 

  • Childs, D. S. Jr., F. R. Keating, Jr., J. E. Rall, M. M. D.Williams and M. H. Power: The effect of varying quantities of inorganic iodide (carrier) on the urinary excretion and thyroidal accumulation of radioiodine in exophthalmic goiter. J. Clin. Invest. 29, 726 (1950).

    CAS  Google Scholar 

  • Christensen, B. C., G. Jensen u. B. Strange: Thyreoidea funktionsprover med radioaktivt jod. Ugeskr. Laeg. 114, 1525 (1952).

    PubMed  CAS  Google Scholar 

  • Clark, D. E., R. H. Moe and E. E. Adams: The rate of conversion of administered inorganic radioactive iodine into protein-bound iodine of plasma as an aid in the evaluation of thyroid function. Surgery 26, 331 (1949).

    PubMed  CAS  Google Scholar 

  • Clark, G. M., and M. Concannon: Persönliche Mitteilung.

    Google Scholar 

  • Clayton, C. G.: Irregularities of iodine assimilation by the follicles of the rat thyroid. Brit. J. Radiol. 26, 99 (1953).

    PubMed  CAS  Google Scholar 

  • Clayton, J. C., A. A. Free, J. E. Page, G. F. Somers and E. A. Woollett: [1] Absorption and excretion of dl-thyroxine labelled with radioactive iodine. Biochemic. J. 45, 20 (1949).

    Google Scholar 

  • Clayton, J. C., A. A. Free, J. E. Page, G. F. Somers and E. A. Woollett: [2] Absorption and excretion of the mono-sodium salt of thyroxine labelled with radioactive iodine. Biochemic. J. 46, 598 (1950).

    CAS  Google Scholar 

  • Closuit, M.: Radioiode, métabolisme basal et cholésterinémie. Discordances observées lors l’étude fonctionelle de la glande thyroide. Helvet. med. Acta 19, 363 (1952).

    CAS  Google Scholar 

  • Cook, E. B.: Persönliche Mitteilung.

    Google Scholar 

  • Cope, O., R. W. Rawson and J. W. McArthur: The hyperfunctioning single adenoma of the thyroid. Surg. etc. 84, 415 (1947).

    CAS  Google Scholar 

  • Corbett, B. D., and A. J. Honour: Design of directional counters for clinical use. Nucle-onics 9, 43 (1951).

    Google Scholar 

  • Corrigan, K. E., and H. S. Hayden: Diagnostic studies with radioactive isotope tracers. Radiology 59, 1 (1952).

    PubMed  CAS  Google Scholar 

  • Cortell, R. E., and R. W. Rawson: The effect of thyroxine on the response of the thyroid gland to thyrotropic hormone. Endocrinology (Springfield, Ill.) 35, 488 (1944).

    CAS  Google Scholar 

  • Costa, A.: Il radioiodo nella analisi funzionale délia tiroide e nella diagnostica e terapia della tireopatie. Tireopatie (Torino) 3, 537 (1954).

    Google Scholar 

  • Crispell, K. R., W. Parson and P. Sprinkle: A simplified technique for the diagnosis of hyperthyroidism, utilizing the one-hour uptake of orally administered I131. J. Clin. Endocrin. 13, 221 (1953).

    CAS  Google Scholar 

  • Critchlow, A., and M. K. Goldfinch: The preparation of thyroxine labelled with 131I and its use as an analytical tool. A. E. R. E. Harwell Radioisotope Conference 1954. Vol. I., S. 271. London: Butterworths 1954.

    Google Scholar 

  • Dailey, M. E., S. Lindsay and R. E. Miller: Histologic lesions in the thyroid gland of patients receiving radioiodine for hyperthyroidism. J. Clin. Endocrin. 13, 1513 (1953).

    CAS  Google Scholar 

  • Danowsky, D. S., F. Mateer, F. A. Weigand, J. H. Peters and J. H. Greenwald: Serum iodine fractions in subjects receiving potassium iodide in small dosage. J. Clin. Endocrin. 10, 519 (1950).

    Google Scholar 

  • Davenport, H. W.: The secretion of iodide by the gastric mucosa. Gastroenterology 1, 1055 (1943).

    CAS  Google Scholar 

  • Deiss, W. P., E. C. Albright and F. C. Larson: [1] A study of the nature of the circulating thyroid hormone in euthyroid and hyperthyroid subjects by use of paper electrophoresis. J. Clin. Invest. 31, 1000 (1952).

    PubMed  CAS  Google Scholar 

  • Deiss, W. P., E. C. Albright and F. C. Larson: [2] Comparison of serum protein binding of thyroxine and triiodothyronine. J. Lab. a. Clin. Med. 42, 799 (1953).

    Google Scholar 

  • Deltour, G., et J. Bekaert: Effet de la 1-3:5:3’-triiodothyronine sur un cas de myxoedème congénital. Ann. d’Endocrin. 14, 87 (1953).

    CAS  Google Scholar 

  • Derobertis, E.: Cytological and cytochemical bases of thyroid function. Ann. N. Y. Acad. Sci. 50, 317 (1949).

    CAS  Google Scholar 

  • Dirnagl, K., u. H. Presch: Untersuchungen über die Jodresorption im Bade mit Hilfe von Radiojod. Klin. Wschr. 1953, 525.

    Google Scholar 

  • Dobyns, B. M., B. N. Skanse and F. Maloof: A method for the preoperative estimation of function in thyroid tumors: its significance in diagnosis and treatment. J. Clin. Endocrin. 9, 1171 (1949).

    CAS  Google Scholar 

  • Dobyns, B. M. and S. L. Steelman: The thyroid stimulating hormone of the anterior pituitary as distinct from the exophthalmos producing substance. Endocrinology (Springflied, 111.) 52, 705 (1953).

    CAS  Google Scholar 

  • Dobyns, B. M., A. L. Vickery, F. Maloof and E. M. Chapman: Functional and histologic effects of therapeutic doses of radioactive iodine on the thyroid of man. J. Clin. Endocrin. 13, 548 (1953).

    CAS  Google Scholar 

  • Dobyns, B. M. and L.A. Wilson: An exophthalmos-producing substance in the serum of patients suffering from progressive exophthalmos. J. Clin. Endocrin. 14, 1393 (1954).

    CAS  Google Scholar 

  • Doniach, I.: [1] The effect of radioactive iodine alone and in combination with methyl - thiouracil and acetylaminofluorene upon tumour production in the rat’s thyroid gland. Brit. J. Cancer 4, 223 (1950).

    PubMed  CAS  Google Scholar 

  • Doniach, I.: [2] The effect of radioactive iodine alone and in combination with methylthiouracil upon tumour production in the rat’s thyroid gland. Brit. J. Cancer 7, 181 (1953).

    PubMed  CAS  Google Scholar 

  • Drummy, W. W. Jr.: The use of radioactive iodine in the detection of thvroid dysfunction. New Engl. J. Med. 249, 970 (1953).

    Google Scholar 

  • Edwards, D. A. W., K. Fletcher and E. N. Rowlands: Antagonism between Perchlorate, iodide, thiocyanate, and nitrate for secretion in human saliva. Analogy with the iodide trap of the thyroid. Lancet 19541, 498.

    Google Scholar 

  • Eitel, H., u. A. Löser: Schilddrüsentätigkeit und Hypophysenvorderlappen. Klin. Wschr. 1932, 1748.

    Google Scholar 

  • Emery, E. W., and N. Veall: Radiation dosimetry from iodine-132. Nature (London) 174, 889 (1954).

    CAS  Google Scholar 

  • Fawcett. D. M., and S. Kirkwood: [1] The synthesis of organically bound iodine by cell-free preparation of thyroid tissue. J. of Biol. Chem. 205, 795 (1953).

    Google Scholar 

  • Fawcett. D. M., and S. Kirkwood: [2] Tyrosine iodinase. J. of Biol. Chem. 209, 249 (1954).

    Google Scholar 

  • Feitelberg, S., P. E. Kaunitz, L. R. Wasserman and S. B. Yohalem: The use of radioactive iodine in the diagnosis of thyroid disease. Amer. J. Med. Sci. 216, 129 (1948).

    PubMed  CAS  Google Scholar 

  • Fellenberg, T. V.: [1] Untersuchungen über den Jodstoffwechsel. Biochem. Z. 174, 341 (1926).

    Google Scholar 

  • Fellenberg, T. V.: [2] Kropf und Trinkwasser in der Schweiz. Mitt. Lebensmittelunters, u. Hyg. 24, 123 (1933).

    Google Scholar 

  • Feller, D. D., I. L. Chaikoff, A. Taurog and H. B. Jones: The changes induced in iodine metabolism of the rat by internal radiation of its thyroid with I131. Endocrinology (Springfield, Ill.) 45, 464 (1949).

    CAS  Google Scholar 

  • Fellinger, K.: [1] Ausgewählte Fragen aus Pathologie und Klinik der Hyperthyreosen. Wien. klin. Wschr. 1950, 217.

    Google Scholar 

  • Fellinger, K.: [2] Zur Differentialdiagnose von intrathorakalen Tumoren. Wien. klin. Wschr. 1952, 797.

    Google Scholar 

  • Fellinger, K.: [3] Zur Grenzziehung zwischen Hvperthyreosen und vegetativen Störungen. Verh. dtsch. Ges. Verdauungs- u. Stoffwechselkrkh. 17, 174 (1953).

    Google Scholar 

  • Fellinger, K., H. Braunsteiner, H. Kolder u. H. Vetter: Nebennierenrinde und Schilddrüsenfunktion. Arch, exper. Path. u. Pharmakol. 219, 440 (1953).

    CAS  Google Scholar 

  • Fellinger, K., R. Höfer u. H. Vetter: [1] Salivary and thyroidal radioiodide clearances of plasma in various states of thyroid function. (Im Druck.)

    Google Scholar 

  • Fellinger. K., R. Höfer u. H. Vetter: [2] Die moderne Schilddrüsendiagnostik mit J131. 14. ärztlicher Fortbildungskurs, Regensburg 1955.

    Google Scholar 

  • Fellinger. K., R. Höfer u. H. Vetter: [3] Die Reproduzierbarkeit kurzzeitiger Radiojoduntersuchungen zur Prüfung der Schilddrüsenfunktion. Zugleich ein Beitrag zur klinischen Verwendung eines neuen radioaktiven Jodisotops, J132. Wien. klin. Wschr. (Im Druck).

    Google Scholar 

  • Fellinger K., E. Mannheimer u. H. Vetter: [1] Der Radioj od-Plasmatest. Wien. Z. inn. Med. 34, 359 (1953).

    PubMed  CAS  Google Scholar 

  • Fellinger K., E. Mannheimer u. H. Vetter: [2] Zur Kenntnis der patho-physiologischen Grundlagen der Diagnostik und Therapie der Schilddrüsenerkrankungen mit radioaktivem Jod. Strahlenther. Sonderb. 33, 81 (1955).

    Google Scholar 

  • Fellinger K. u. H. Vetter.: [1] Radioaktives Jod in der Diagnostik aberranten Schilddrüsengewebes. Wien. klin. Wschr. 1950, 927.

    Google Scholar 

  • Fellinger K. u. H. Vetter.: [2] Radiation therapy by means of internally administered radioactive isotopes. J. Egypt. Med. Assoc. 37, 812 (1954).

    PubMed  CAS  Google Scholar 

  • Fellinger K. u. H. Vetter.: [3] Diagnostische Anwendungen radioaktiver Isotope; in Fellinger, K.: Klinische Fortschritte, Innere Medizin, Vol. II., Wien: Urban & Schwarzenberg 1955.

    Google Scholar 

  • Fellinger K. u. O. Voelkel: Über die Anwendung des Radioj od-Speichertestes zur Diagnostik von Schilddrüsenkrankheiten. Münch, med. Wschr. 1951, 47.

    Google Scholar 

  • Fields, T., and G. V. Leroy: An accurate method for the measurement of radioiodine in the thyroid gland by an external counter. Radiology 58, 57 (1952).

    PubMed  CAS  Google Scholar 

  • Findlay, D., and C. P. Leblond: Partial destruction of rat thyroid by large doses of radioiodine. Amer. J. Roentgenol. 59, 387 (1948).

    CAS  Google Scholar 

  • Fink, K., and R. M. Fink: The formation of monoiodotyrosine from radioiodine in thyroid of rat and man. Science (Lancaster, Pa.) 108, 358 (1948).

    CAS  Google Scholar 

  • Fink, R. M., C. E. Dent and K. Fink: Application of filter paper partition chromatography to radioactive tracer studies. Nature (London) 160, 801 (1947).

    CAS  Google Scholar 

  • Flexner, M., M. Bruger and S. Member: The excretion of iodine by the salivary and gastric glands. Fédérât. Proc. 1, 109 (1942).

    Google Scholar 

  • Foote, J. B., D. H. Mackenzie and N. F. Maclagan: A comparison of radioactive and metabolic methods of investigating thyroid function. Lancet 1952/1, 486.

    Google Scholar 

  • Foote, J. B. and N. F. Maclagan: The thigh-neck clearance. A simplified radioactive test for thyroid function. Lancet 1951/1, 868.

    Google Scholar 

  • Francke, S., and W. N. Robert: Enkele ervaringen met een eenvondige methode voor het onderzoek van de schildklierfunctie met radio-actief jodium. Nederl. Tijdschr. Geneesk. 1953, 2578.

    Google Scholar 

  • Franklin, A. L., and I. L. Chaikoff: The effect of sulfonamides on the conversion in vitro of inorganic iodide to thyroxine and diiodotyrosine by thyroid tissue with radioactive iodine as indicator. J. of Biol. Chem. 152, 295 (1944).

    CAS  Google Scholar 

  • Franklin, A. L., I. L. Chaikoff and S. R. Lerner: The influence of goitrogenic substances on the conversion in vitro of inorganic iodide to thyroxine and diiodotyrosine by thyroid tissue with radioactive iodine as indicator. J. of Biol. Chem. 153, 151 (1944).

    CAS  Google Scholar 

  • Franklin, A. L., S. R. Lerner and I. L. Chaikoff: Effect of thiouracil on the formation of thyroxine and diiodotyrosine by the thvroid gland of the rat with radioactive iodine as indicator. Endocrinology (Springfield, Ill.) 34, 265 (1944).

    CAS  Google Scholar 

  • Fraser, R., Q. J. G. Hobson, D. G. Arnott and E. W. Emery: The urinary excretion of radioiodine as a clinical test for thyroid function. Quart. J. Med. 22, 99 (1953).

    PubMed  CAS  Google Scholar 

  • Freedberg, A. S., and R. Buka: The modifying effect of inorganic iodide administered to thyrotoxic patients previously treated with I131. J. Clin. Invest. 27, 534 (1948).

    PubMed  CAS  Google Scholar 

  • Freedberg, A. S., R. Buka and M. J. Mcmanus: Comparative value and accuracy of measurements of urinary I131 by beta and gamma ray counting. J. Clin. Endocrin. 9, 841 (1949).

    CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: [1] Thyroid function in normal and pathological states as revealed by radioactive iodine studies. I. Thyroid I131 uptake and turnover in euthyroid, hyperthyroid and hypothyroid subjects. Metabolism 1, 26 (1952).

    PubMed  CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz and G. S. Kurland: [2] Thyroid function in normal and pathological states as revealed by radioactive iodine studies. II. Factors influencing the uptake and turnover of I131 by the thvroid gland. Metabolism 1, 36 (1952).

    PubMed  CAS  Google Scholar 

  • Freedberg, A. S., D. L. Chamovitz, A. Ureles and M. Van Dilla: The direct measurement of I131 uptake in the thyroid gland; further observations. J. Clin. Endocrin. 10, 910 (1950).

    CAS  Google Scholar 

  • Freedberg, A. S., G. S. Kurland and H. L. Blumgart: Pathologic effects of I131 on the normal thvroid gland of man. J. Clin. Endocrin. 12, 1315 (1952).

    CAS  Google Scholar 

  • Freedberg, A. S., A. Ureles, S. Hertz and B. Seamon: The serum level of protein bound radioactive iodine (I131) in the diagnosis of hyperthyroidism. Proc. Soc. Exper. Biol. a. Med. 70, 697 (1949).

    Google Scholar 

  • Freedberg, A. S., M. Van Dilla and M. J. Mcmanus: A new simple method for accurate measurement of urinary I131 after tracer and therapeutic doses. J. Clin. Endocrin. 10, 437 (1950).

    CAS  Google Scholar 

  • Freinkel, N., and S. H. Ingbar: Concentration gradients for inorganic I131 and chloride in mixed human saliva. J. Clin. Invest. 32, 1077 (1953).

    PubMed  CAS  Google Scholar 

  • Gemmill, C. L.: Comparison of activity of thyroxine and SS’-triiodothyronine. Amer. J. Physiol. 172, 286 (1953).

    CAS  Google Scholar 

  • Gennes, L. De, G. Deltour et J. Leprat: Effet de la 1-3:5:3’-triiodothyronine sur dix cas d’insuffisance thyroidienne. Presse méd. 1953, 1119.

    Google Scholar 

  • Gerbaulet, K., u. W. Maurer: Papierelektrophoretische und papierchromatographische Untersuchungen der organischen Jod-Verbindungen des Serums. Strahlenther. Sonderb. 33, 116 (1955).

    Google Scholar 

  • Ghosh, B. N., D. M. Woodbury and G. Sayers: Quantitative effects of thyrotropic hormone on I131 accumulation in thyroid and plasma proteins of hypophysectomized rats. Endo-crinology (Springfield, Ill.) 48, 631 (1951).

    CAS  Google Scholar 

  • Gilbert-Dreyfus, G., D. M. Woodbury, Ambrosino et Triantaphyllidis: Etude du métabolisme de l’iode radio-actif chez le sujet normal et l’hyperthyroidien. Son utilisation en vue d’élucider les cas restés douteux après l’application du test standard. Semaine Hôp. 1952, 3905.

    Google Scholar 

  • Gilbert-Dreyfus, G. et M. Zara: L’épreuve de L’I131 dans les affections thyroidiennes. Sa valeur diagnostique Ann. d’Endocrin. 11, 528 (1950).

    CAS  Google Scholar 

  • Gilbert-Dreyfus, G., M. Zara, M. Ayache et Lemaignen: Diagnostic des affections thyroidiennes par la déter-mination de la courbe de fixation thyroidienne de I131. Semaine Hôp. 1951, 2383.

    Google Scholar 

  • Gilbert-Dreyfus, G. et M. Zara: Le diagnostic des hyperthyroidies frustes par l’épreuve de fixation thyroidienne de l’iode radio-actif. Presse méd. 1952, 617.

    Google Scholar 

  • Gilbert-Dreyfus, G., M. Zara, G. Ambrosino et M. Ayache: Courbe d’utilisation thyroidienne de l’iode radioactif. L’angle de fuite test d’hyperthyroidie. Bull. Soc. méd. Hôp. Paris 66, 1793 (1950).

    PubMed  CAS  Google Scholar 

  • Gilliland, I.: Untersuchungen über das Schilddrüsen-Stimulierende Hormon im Serum von Patienten mit Schilddrüsenerkrankungen. Strahlenther. Sonderb. 33, 126 (1955).

    Google Scholar 

  • Gilliland, I. and J. I. Strudwick: The assay of thyrotrophs hormone by the discharge of 131I from the thyroid of day-old chicks. Clin. Sci. 12, 265 (1953).

    PubMed  CAS  Google Scholar 

  • Godley, A. F., and J. B. Stanbury: Preliminary experience in the treatment of hyper-thyroidism with potassium Perchlorate. J. Clin. Endocrin. 14, 70 (1954).

    CAS  Google Scholar 

  • Goldberg, R. C., and I. L. Chaikoff: [1] The cytological changes that occur in the anterior pituitary glands of rats injected with various doses of I131 and their significance in the estimation of thyroid function. Endocrinology (Springfield, Ill.) 46, 91 (1950).

    CAS  Google Scholar 

  • Goldberg, R. C., and I. L. Chaikoff: [2] Induction of thyroid cancer in the rat by radioactive iodine. Arch, of Path. 53, 22 (1952).

    CAS  Google Scholar 

  • Goldberg, R. C., I. L. Chaikoff, S. Lindsay and D. D. Feller: Histopathological changes induced in the normal thyroid and other tissues of the rat by internal radiation with various doses of radioactive iodine. Endocrinology (Springfield, Ill.) 46, 72 (1950).

    CAS  Google Scholar 

  • Goldsmith, R. E.: Experiences with the radioiodine tracer test in radioiodine-treated thyrotoxic patients. Amer. J. Med. Sci. 227, 403 (1954).

    PubMed  CAS  Google Scholar 

  • Goldsmith, R. E., J. B. Stanbury and G. L. Brownell: The effect of thyrotropin on the release of hormone from the human thyroid. J. Clin. Endocrin. 11, 1079 (1951).

    CAS  Google Scholar 

  • Goldsmith, R. E., C. D. Stevens and L. Schiff: Concentration of iodine in the human stomach and other tissues as determined with radioactive iodine. J. Labor, a. Clin. Med. 35, 497 (1950)

    CAS  Google Scholar 

  • Goodwin, J. F., A. G. Macgregor, H. Miller and E. J. Wayne: The use of radioactive iodine in the assessment of thyroid function. Quart. J. Med. 20, 353 (1951).

    PubMed  CAS  Google Scholar 

  • Goodwin, J. F., H. Miller and E. J. Wayne: A comparison of the anti-thyroid activity of paraamino- benzoic acid and thiouracil compounds. Lancet 1949 II, 1211.

    Google Scholar 

  • Goodwin, W. E.: Total accountable radioiodine. Combined thyroid uptake and urinary excretion of I131 in the study of thyroid function. Metabolism 2, 238 (1953).

    PubMed  CAS  Google Scholar 

  • Goodwin, W. E., B. Cassen and F. K. Bauer: Thyroid gland weight determination from thyroid scintigrams with post mortem verification. Radiology 61, 88 (1953).

    PubMed  CAS  Google Scholar 

  • Gorbman, A.: [1] Effects of radiotoxic dosages of I131 upon thyroid and contiguous tissues in mice. Proc. Soc. Exper. Biol. a. Med. 66, 212 (1947).

    CAS  Google Scholar 

  • Gorbman, A.: [2] Degenerative and regenerative changes in the thyroid gland following high dosage of radioactive iodine. Ann. N. Y. Acad. Sci. 11, 201 (1949).

    CAS  Google Scholar 

  • GORBMAN, A.: [3] Functional and structural changes consequent to high dosages of radioactive iodine. J. Clin Endocrin. 10, 1177 (1950).

    CAS  Google Scholar 

  • Gorbman, A. and H. M. Evans: Beginning of function in the thyroid of the fetal rat. Endocrinology (Springfield, Ill.) 32, 113 (1943).

    CAS  Google Scholar 

  • Gordon, A. H., J. Gross, D. O’connor and R. Pitt-Rivers: Nature of the circulating thyroid hormone-plasma complex. Nature (London) 169, 19 (1952).

    CAS  Google Scholar 

  • Grampa, G., E F. Marinoni: Effetto di diete iper e ipo-iodiche sulla tiroide: osservazioni istoradioautografiche con iodo radioattivo. Boll. Soc. ital. Biol. Sper. 27, 1499 (1951).

    PubMed  CAS  Google Scholar 

  • Greer, M. A.: [1] Correlation of the 24-hour radioiodine uptake of the human thyroid gland with the six- and eight-hour uptakes and the “accumulation gradient”. J. Clin. Invest. 30, 301 (1951).

    PubMed  CAS  Google Scholar 

  • Greer, M. A.: [2] The effect on endogenous thyroid activity of feeding desiccated thyroid to normal human subjects. New Engl. J. Med. 244, 385 (1951).

    CAS  Google Scholar 

  • Greer, M. A.: [3] The results of feeding desiccated thyroid to thyrotoxic subjects. J. Clin. Invest. 30, 644 (1951).

    Google Scholar 

  • Greer, M. A.: [4] The role of the hypothalamus in the control of thyroid function. J. Clin. Endocrin. 12, 1259 (1952).

    CAS  Google Scholar 

  • Greer, M. A. and G. E. Smith: Method for increasing accuracy of I131 uptake as test of thyroid function by use of desiccated thyroid. J. Clin. Endocrin. 14, 1374 (1954).

    CAS  Google Scholar 

  • Griesbach, W. E., T. H. Kennedy and H. D. Purves: Studies on experimental goiter. VI. Thyroid adenomatas in rats on brassica seed diet. Brit. J. Exper. Path. 26, 18 (1945).

    CAS  Google Scholar 

  • Gross, J.: Thyroid hormones. Brit. Med. Bull. 10, 218 (1954).

    PubMed  CAS  Google Scholar 

  • Gross, J. and C. P. Leblond: [1] Distribution of a large dose of thyroxine labeled with radioiodine in the organs and tissues of the rat. J. of Biol. Chem. 171, 309 (1947).

    CAS  Google Scholar 

  • Gross, J. and C. P. Leblond: [2] Metabolism of the thyroid hormone in the rat as shown by physiological doses of labeled thyroxine. J. of Biol. Chem. 184, 489 (1949).

    Google Scholar 

  • Gross, J. and C. P. Leblond: [3] Metabolites of thyroxine. Proc. Soc. Exper. Biol. a. Med. 76, 686 (1951).

    CAS  Google Scholar 

  • Gross, J. and C. P. Leblond: [4] The presence of free iodinated compounds in the thyroid and their passage into the circulation. Endocrinology (Springfield, Ill.) 48, 714 (1951).

    CAS  Google Scholar 

  • Gross, J., C. P. Leblond, A. E. Franklin and J. H. Quastel: Presence of iodinated amino acids in unhydrolyzed thyroid and plasma. Science (Lancaster, Pa.) 111, 605 (1950).

    CAS  Google Scholar 

  • Gross, J. and R.Pitt-Rivers: [1] Unidentified iodine compounds in human plasma. Lancet 1951 II, 766.

    Google Scholar 

  • Gross, J. and R.Pitt-Rivers: [3] Physiological activity of 3:5:3 1-1-triiodothyronine. Lancet 1952 I, 593.

    Google Scholar 

  • Gross, J. and R.Pitt-Rivers: [4] Experimental study of thyroid metabolism with radioactive iodine. Brit. Med. Bull. 8, 136 (1952).

    CAS  Google Scholar 

  • Gross, J. and R.Pitt-Rivers: [5] 3:5:31-Triiodothyronine. I. Isolation from thyroid gland and synthesis. Biochemic. J. 53, 645 (1953).

    CAS  Google Scholar 

  • Gross, J. and R.Pitt-Rivers: [6] 3:5:31-Triiodothyronine. II. Physiological activity. Biochemic. J. 53, 652 (1953).

    CAS  Google Scholar 

  • Gross, J., R.Pitt-Rivers and W. R. Trotter: Effect of 3:5:3’-1-triiodothyronine in myxedema. Lancet 1952 I, 1044.

    Google Scholar 

  • Guinet, P., et M. Berger: [1] L’épreuve à la thyréostimuline dans le diagnostic étio-patho- génique du myxoedème. Ann. d’Endocrin. 12, 585 (1951).

    CAS  Google Scholar 

  • Guinet, P., et M. Berger: [2] Résultats personelles obtenus par les explorations au radio-iode dans le goitre du jeune. Ann. d’Endocrin. 13, 790 (1952).

    CAS  Google Scholar 

  • Halmi, N. S.: [1] Thyroidal iodide trapping as influenced by serum iodide levels and thyrotropin. Endocrinology (Springfield, Ill.) 54, 97 (1954).

    CAS  Google Scholar 

  • Halmi, N. S.: [2] Regulation of the rat thyroid in short term iodine deficiency. Endocrinology (Springfield, Ill.) 54, 216 (1954).

    CAS  Google Scholar 

  • Halmi, N. S. and B. N. Spirtos: Analysis of action of propylthiouracil on the pituitary-thyroid axis of rats. Endocrinology (Springfield, Ill.) 55, 613 (1954).

    CAS  Google Scholar 

  • Hamilton, H. E., W. M. Kirkendahl and S. B. Barker: Radioactive iodine uptake of the thyroid and plasma protein bound iodine in subacute thyroiditis. J. Clin. Invest. 29, 819 (1950).

    PubMed  CAS  Google Scholar 

  • Hamilton, J. G.: [1] The rates of absorption of the radioactive isotopes of sodium, potassium, chlorine, bromine and iodine in normal human subjects. Amer. J. Physiol. 124, 667 (1938).

    CAS  Google Scholar 

  • Hamilton, J. G.: [2] The use of radioactive tracers in biology and medicine. Radiology 39, 541 (1942).

    CAS  Google Scholar 

  • Hamilton, J. G. and M. H. Soley: [1] Studies in iodine metabolism by the use of a new radioactive isotope of iodine. Amer. J. Physiol. 127, 557 (1939).

    CAS  Google Scholar 

  • Hamilton, J. G. and M. H. Soley: [2] Studies in iodine metabolism of the thyroid gland in situ by the use of radioiodine in normal subjects and in patients with various types of goiter. Amer. J. Physiol. 131, 135 (1940).

    CAS  Google Scholar 

  • Hamolsky, M. W., A. S. Freedberg, G. S. Kurland and L. Wolsky: The exchangeable thyroid hormonal pool. I. Its magnitude and rate of turnover in various thyroid states in man. J. Clin. Invest. 32, 453 (1953).

    CAS  Google Scholar 

  • Hanbury, E. M. Jr., J. Heslin, L. G. Stang, Jr., W. D. Tucker and J. E. Rall: The diagnostic use of I132. J. Clin. Endocrin. 14, 1530 (1954).

    CAS  Google Scholar 

  • Harington, C. R.: Twenty-five years of research on the biochemistry of the thyroid gland. Endocrinology (Springfield, Ill.) 49, 401 (1951).

    CAS  Google Scholar 

  • Harington, C. R. and S. S. Randall: Observations on the iodine-containing compounds of the thyroid gland. Isolation of dl-3:5:diiodotyrosine. Biochemic. J. 23, 379 (1929).

    Google Scholar 

  • Harsha, W. X.: Evaluation of the conversion of radioactive inorganic iodine to protein-bound iodine as a diagnostic aid in thyroid dysfunction. J. Clin. Endocrin. 11, 1524 (1951).

    CAS  Google Scholar 

  • Heath, C. W., and H. W. Fullerton: The rate of absorption of iodide and glycine from the gastrointestinal tract in normal persons and in diseased conditions. J. Clin. Invest. 14, 475 (1935).

    PubMed  CAS  Google Scholar 

  • Heinemann, M., C. E. Johnson and E. B. Man: Serum precipitable iodine concentrations during pregnancy. J. Clin. Invest. 27, 91 (1948).

    CAS  Google Scholar 

  • Hemtng, A. E., and D. E. Holtkamp: Comparative effects of thyroxine and triiodothyronine on oxygen consumption of rats. Federat. Proc. 12, 330 (1953).

    Google Scholar 

  • Hertz, S., A.Roberts and R.D. Evans: Radioactive iodine as an indicator in thyroid physiology. Proc. Soc. Exper. Biol. a. Med. 38, 510 (1938).

    Google Scholar 

  • Hertz, S., A.Roberts, R.D. Evans, J. H. Means and R. D. Evans: Radioactive iodine as an indicator in thyroid physiology. Iodine collection by normal and hyperplastic thyroids in rabbits. Amer. J. Physiol. 128, 565 (1940).

    Google Scholar 

  • Hertz, S., G. E. Whitham, A. Macleod, L. Hanopol and A. Miller: An analysis of the multi- counter technique for the measurement of radioactive sources independent of the geometry. Science (Lancaster, Pa.) 111, 576 (1950).

    CAS  Google Scholar 

  • Hickey, F. C., and G. L. Brownell: Dynamic analysis of iodine metabolism in 4 normal subjects. J. Clin. Endocrin. 14, 1423 (1954).

    CAS  Google Scholar 

  • Hidalgo, J. W., S. B. Nadler, T. Bloch and R. T. Nieset: A technic for measurement of radioactive iodine (131) uptake by the human thyroid gland. Proc. Soc. Exper. Biol. a. Med. 77, 764 (1951).

    CAS  Google Scholar 

  • Hird, F. J. R., and V. M. Trikojus: Partition paper chromatography with thyroxine and analogues. Austral. J. Sci. 10, 185 (1948).

    CAS  Google Scholar 

  • Hlad, C. J. Jr., and N. S. Bricker: Renal function and I131 clearance in hyperthyroidism and myxedema. J. Clin. Endocrin. 14, 1539 (1954).

    CAS  Google Scholar 

  • Hobson, Q. J. G.: Die Diagnose von Schilddrüsenerkrankungen durch Messung der Radio-jodausscheidung im Harn. Strahlenther. Sonderb. 33. 90 (1955).

    Google Scholar 

  • Hofmann-Credner, D.: [1] Isotopenstudien über die Jodresorption. Die Aufnahme von elementarem Jod durch die Atemwege. Wien. med. Wschr. 1954, 253.

    Google Scholar 

  • Hofmann-Credner, D.: [2] Experimentelle Untersuchungen zur Jodaufnahme durch die Haut und Lunge beim Menschen. Arch, internat. Pharmacodynamie 97, 363 (1954).

    CAS  Google Scholar 

  • Hofmann-Credner, D. u. H. Spitzy: Zur Frage der perkutanen und respiratorischen Jodaufnahme. Arch, physik. Ther. 6, 171 (1954).

    CAS  Google Scholar 

  • Holthusen, H., u. R. Braun: Grundlagen und Praxis der Röntgenstrahlendosierung. Leipzig: G. Thieme 1933.

    Google Scholar 

  • Honour, A. J., N. B. Myant and E. N. Rowlands: Secretion of radioiodine in digestive juices and milk in man. Clin. Sci. 11, 447 (1952).

    CAS  Google Scholar 

  • Horst, W.: [1] Die diagnostische und therapeutische Anwendung des Radiojodids (131J). Fortschr. Röntgenstr. 77. 567 (1952).

    CAS  Google Scholar 

  • Horst, W.: [2] Methoden und Ergebnisse des Radiojodstoffwechselstudiums zur Diagnostik thyreoida- ler und extrathyreoidaler Erkrankungen. Klin. Wschr. 1952, 439.

    Google Scholar 

  • Horst, W.: [3] Persönliche Mitteilung.

    Google Scholar 

  • Horst, W. u. G. A. V. Harnack: Hypothyreosen im Kindesalter. Die Differenzierung des hypo- thyreotischen Zustandsbüdes beim Kinde durch ein spezielles Radiojodstoffwechselstudium. Dtsch. med. Wschr. 1953, 1259.

    Google Scholar 

  • Horst, W. u. F. Kuhlencordt: Ergebnisse der Strahlentherapie mit Radiojod (J131) bei 150 Patienten mit Schilddrüsenüberfunktion. Zugleich ein Beitrag zur Pathogenese der Hyperthyreose auf Grund des Verhaltens des Jodstoffwechsels nach der J131-Therapie. Dtsch. med. Wschr. 1954, 399.

    Google Scholar 

  • Horst, W., u. H. Rösler: Der Transport des Hormonjods im menschlichen Serum untersucht mit Papierelektrophorese und Radiojod. (Zugleich ein Beitrag zur Frage der Existenz von sog. Zwischenfraktionen.) Klin. Wschr. 1953, 13.

    Google Scholar 

  • Hoskins, R. G.: The thyroid-pituitary apparatus as a servo (feed-back) mechanism. J. Clin. Endocrin. 9, 1429 (1949).

    Google Scholar 

  • Hubble, D.: Familial cretinism. Lancet 1953 I, 1112.

    Google Scholar 

  • Hutchison, J. H., and E. M. Mcgirr: Hypothyroidism as an inborn error of metabolism. J. Clin. Endocrin. 14, 869 (1954).

    CAS  Google Scholar 

  • Ingbar, S. H.: [1] A new method for the study of thyroidal function in man, using radioactive iodine. J. Clin. Invest. 32, 577 (1953).

    Google Scholar 

  • Ingbar, S. H.: [2] Simultaneous measurement of the iodide-concentrating and protein-binding capacities of the normal and hyperfunctioning human thyroid gland. J. Clin. Endocrin. 15, 238 (1955).

    CAS  Google Scholar 

  • Ingbar, S. H.: [3] The influence of single doses of propylthiouracil on the kinetics of iodine accumulation by the thyroid glands of normal and hyperthyroid subjects. J. Clin. Endocrin. 15, 331 (1955).

    CAS  Google Scholar 

  • Ingbar, S. H., N. Freinkel, P. D. Hoeprich and J. W. Athens: The concentration and significance of the butanol-extractable I131 of serum in patients with diverse states of thyroid function. J. Clin. Invest. 33, 388 (1954).

    PubMed  CAS  Google Scholar 

  • Jaffe, H. L., and R.E. Ottoman: Evaluation of radioiodine test for thyroid function. J. Amer. Med. Assoc. 143, 515 (1950).

    CAS  Google Scholar 

  • Jakob, A.: Persönliche Mitteilung.

    Google Scholar 

  • Jefferies, W. Mck., R.P.Levy, W. G. Palmer, J. P. Storaasli and L. W. Kelly, Jr.: The value of a single injection of thyrotropin in the diagnosis of obscure hvpothvroidism. New Engl. J. Med. 249, 876 (1953).

    CAS  Google Scholar 

  • Johns, M. W., J. H. Gregson, S. C. Foster, C. H. Jaimet and H. G. Thode: Radioiodine 131 in the diagnosis of thyroid function. Canad. Med. Assoc. J. 68, 132 (1953).

    PubMed  CAS  Google Scholar 

  • Johnson, H. W., and A. Albert: The excretion and distribution of iodine-131 following administration of physiologic amounts of labeled iodide, diiodotyrosine and thyroxine in the rat. Endocrinology (Springfield, Ill.) 48, 669 (1951).

    CAS  Google Scholar 

  • Johnson, P. C., and W. H. Beierwaltes: The urinary and fecal excretion of I131 from labeled sodium-l-thyroxine in various thyroid states and in euthyroids with bile fistulas’. J. Labor, a. Clin. Med. 41, 676 (1953).

    CAS  Google Scholar 

  • Joliot, F., R. Courrier, A. Horeau et P. Sue: Sur l’obtention de la thyroxine marquée par le radioiode et son compartment dans l’organisme. C. r. Acad. Sci. (Paris) 218, 769 (1944).

    CAS  Google Scholar 

  • Junkmann, K.: Persönliche Mitteilung.

    Google Scholar 

  • Keating, F. R. Jr., and A. Albert: The metabolism of iodine in man as disclosed with the use of radioiodine. Recent Progr. in Hormone Res. 4, 429 (1948).

    Google Scholar 

  • Keating, F. R. Jr., S.F.Haines, M. H. Power and M. M. D. Williams: The radioiodine-accumulating function of the human thyroid gland as a diagnostic test in clinical medicine. J. Clin. Endocrin. 10, 1425 (1950).

    Google Scholar 

  • Keating, F. R. Jr., M. H. Power, J. Berkson and S. F. Haines: The urinary excretion of radioiodine in various thyroid states. J. Clin. Invest. 26, 1138 (1947).

    CAS  Google Scholar 

  • Keating, F. R. Jr., R. W. Rawson, W. Peacock and R. D. Evans: The collection and loss of radioactive iodine compared with the anatomic changes induced in the thyroid of the chick by the injection of thyrotropic hormone. Endocrinology (Springfield, Ill.) 36, 137 (1945).

    CAS  Google Scholar 

  • Keating, F. R. Jr., J. C. Wang, T. J. Luellen, M. M. D. Williams, M. H. Power and W. M. McConahey: The measurement of the iodine-accumulating function of the human thyroid gland. J. Clin. Invest. 28, 217 (1949).

    CAS  Google Scholar 

  • Kelly, F. J.: Observations on the calculation of thyroid weight using empirical formulae. J. Clin. Endocrin. 14, 326 (1954).

    CAS  Google Scholar 

  • Kelly, F. J., C. T. Ray, S. A. Threefoot and G. E. Burch: Influence of self-absorption, volatization, and deliquescence in counting of radioelements. J. Labor, a. Clin. Med. 35, 606 (1950).

    CAS  Google Scholar 

  • Kendall, E. C.: The isolation in crystalline form of the compound containing iodide which occurs in the thyroid. J. Amer. Med. Assoc. 64, 2042 (1915).

    CAS  Google Scholar 

  • Keston, A. S., E. D. Goldsmith, A. S. Gordon and H. A. Charipper: The effect of thiourea upon the metabolism of iodine by rat thyroid. J. of Biol. Chem. 152, 241 (1944).

    CAS  Google Scholar 

  • Kirkeby, K., u. P. Leren: Radioaktivt jod i diagnosen av nervöse lidelser med stoffskifte- forandring. Nord. Med. 48, 1266 (1952).

    PubMed  CAS  Google Scholar 

  • Kirkland, R. H.: Impaired organic binding of radioiodine by the thyroid following radioiodine treatment of hyperthyroidism. J. Clin. Endocrin. 14, 565 (1954).

    CAS  Google Scholar 

  • Kirkwood, S.: Persönliche Mitteilung.

    Google Scholar 

  • Klauer, F., u. H. Billion: Zur Methodik des Radiojod-Testes der Schilddrüse. Fortschr. Röntgenstr. 75, 352 (1951).

    CAS  Google Scholar 

  • Klitgaard, H. M.: Biliary and urinary I131 excretion in euthyroid, hyper- and hypothyroid rats injected with labeled thyroxine. Proc. Soc. Exper. Biol. a. Med. 82, 578 (1953).

    CAS  Google Scholar 

  • Klotz, H.P., et P. Lumbroso: Note sur les fixations fortes d’iode radioactif par la thyroide sans hypersécrétion thyroidienne. Bull. Soc. méd. Hôp. Paris 68, 794 (1952).

    PubMed  CAS  Google Scholar 

  • Koller, F., u. W. Siegenthaler: Die Schilddrüsenfunktion beim Klinefelter-Syndrom. Schweiz, med. Wschr. 1955, 8.

    Google Scholar 

  • Kriss, P.: [1] Uptake of radioactive iodine, I131, by the thyroid gland after administration of tracer doses. J. Clin. Endocrin. 10, 812 (1950).

    CAS  Google Scholar 

  • Kriss, P.: [2] Uptake of radioactive iodine after i. v. administration of tracer doses. J. Clin. Endocrin. 11, 289 (1951).

    CAS  Google Scholar 

  • Kroc, R. L., G. E. Phillips, N. R. Stasilli and S. Malament: Antigoitrogenic and calorigenic assay of thyreoglobulin, desiccated thyroid and 1-thyroxine by different routes of administration in rats. J. Clin. Endocrin. 14, 56 (1954).

    CAS  Google Scholar 

  • Kühne, P., u. H. Billion: Die Altersregression der Schilddrüsenfunktion im Radiojodtest. Ärztl. Wschr. 1955, 62.

    Google Scholar 

  • Kümmer, P.: Die Erfassung sympathikotoner Funktionsstörungen durch die Radioj oddiagnostik. Münch, med. Wschr. 1954, 1479.

    Google Scholar 

  • Kurland, G. S., A. S. Freedberg and J. Fishman: Effect of thyrotropin on changes in thyroid function following administration of I131 to euthvroid cardiac patients. J. Clin. Endocrin. 14, 572 (1954).

    CAS  Google Scholar 

  • Kuschinsky, G.: Über die Bedingungen der Sekretion des thyreotropen Hormons der Hypophyse. Arch, exper. Path. u. Pharmakol. 170, 510 (1933).

    CAS  Google Scholar 

  • Lachapele, A. P., P. Blanquet et L. Capot: Description d’un dispositif de cartographie thyroidienne. J. méd. Bordeaux 129, 792 (1952).

    PubMed  CAS  Google Scholar 

  • Laidlaw, J. C.: Nature of the circulating thyroid hormone. Nature (London) 164, 927 (1949).

    CAS  Google Scholar 

  • Lamarque, P., E. Thibaut, A. Pages et Gary-Bobo: Etude comparative du métabolisme basal et du marquage par l’I131 dans 116 cas de dysthyroidie. Ann. d’Endocrin. 14, 955 (1953).

    CAS  Google Scholar 

  • Lamerton, L. F.: Grundsätzliches zur Anwendung von radioaktiven Isotopen beim Menschen mit besonderer Berücksichtigung der Probleme der Strahlenbiologie. Strahlenther. Son- derb. 33, 1 (1955).

    Google Scholar 

  • Lang, N., u. H. Nöller: Relationen der Radiojod-Ausscheidungsgeschwindigkeit bei Gesunden und Hyperthyreosen. Klin. Wschr. 1953, 846.

    Google Scholar 

  • Laroche, G., L. Mallet et J. Tremolieres: [1] Applications cliniques et étude critique du test thyroidien à l’I131. Fol. endocrinol. (Pisa) 6, 165 (1953).

    Google Scholar 

  • Laroche, G., L. Mallet et J. Tremolieres: [2] Applications cliniques et étude du test thyroidien à l’iode131. Semaine Hôp. 1953, 827.

    Google Scholar 

  • Larson, F. C., W. P. Deiss and E. C. Albright: Localization of protein-bound radioactive iodine by filter paper electrophoresis. Science (Lancaster, Pa.) 115, 626 (1952).

    CAS  Google Scholar 

  • Larson, R. A., F. R. Keating, Jr., W.Peacock and R. W. Rawson: [1] A comparison of the effect of thiouracil and injected thyrotropic hormone on the collection of radioactive iodine and the anatomic changes induced in the thyroid of the chick. Endocrinology (Springfield, Ill.) 36, 149 (1945).

    CAS  Google Scholar 

  • Larson, R. A., F. R. Keating, Jr., W.Peacock and R. W. Rawson: [2] The effect of thiouracil on the collection of radioactive iodine by the thyroid of the chick. Endocrinology (Springfield, Ill.) 36, 160 (1945).

    CAS  Google Scholar 

  • Leblond, C. P., M. B. Fertman, I. D. Puppel and G. M. Curtis: Radioiodine autography in studies of human goitrous thyroid glands. Arch, of Path. 41, 510 (1946).

    CAS  Google Scholar 

  • Leblond, C. P., and J. Gross: [1] Mechanism of the secretion of the thvroid hormone. Canad. Med. Assoc. J. 58, 404 (1948).

    Google Scholar 

  • Leblond, C. P., and J. Gross: [2] Thyreoglobulin formation in the thyroid follicle visualized by the “coated autograph” technique. Endocrinology (Springfield, Ill.) 43, 306 (1948).

    CAS  Google Scholar 

  • Leblond, C. P., and J. Gross: [3] The mechanism of the secretion of thyroid hormone. J. Clin. Endocrin. 9, 149 (1949).

    CAS  Google Scholar 

  • Leblond, C. P., and W. Mann: Fixation of iodine by the thyroid of rats given diets deficient in iodine. Proc. Soc. Exper. Biol. a. Med. 49, 102 (1942).

    CAS  Google Scholar 

  • Leblond, C. P., W. L. Percival and J. Gross: Autographic localization of radio-iodine in stained sections of thyroid gland by coating with photographic emulsion. Proc. Soc. Exper. Biol. a. Med. 67, 74 (1948).

    CAS  Google Scholar 

  • Leblond, C. P., I. D. Puppel, E. Riley, M. Radike and G. M. Curtis: Radioiodine and iodine fractionation studies of human goitrous glands. J. of Biol. Chem. 162, 275 (1946).

    CAS  Google Scholar 

  • Leblond, C. P. et P. Sue: [1] Passage de l’iode radioactif (I128) dans la thyroide stimulée par l’hormone thyréotrope de l’hypophyse. C. r. Soc. Biol. (Paris) 133, 543 (1940).

    CAS  Google Scholar 

  • Leblond, C. P. et P. Sue: [2] Iodine fixation in the thyroid as influenced by the hypophysis and other factors. Amer. J. Physiol. 134, 549 (1941).

    CAS  Google Scholar 

  • Lee, N. D., and R.H. Williams: The intracellular localization of labeled thyroxine and labeled insulin in mammalian liver. Endocrinology (Springfield, Ill.) 54, 5 (1954).

    CAS  Google Scholar 

  • Lein, A.: Studies on the fixation of radioactive iodine by the rabbit thyroid. Endocrinologv (Springfield, Ill.) 32, 429 (1943).

    CAS  Google Scholar 

  • Lerman, J.: [1] Iodine components of the blood. Circulating thyreoglobulin in normal persons and in persons with thyroid disease. J. Clin. Invest. 19, 555 (1940).

    PubMed  CAS  Google Scholar 

  • Lerman, J.: [2] The physiological activity of 1-triiodothyronine. J. Clin. Endocrin. 13, 1341 (1953).

    CAS  Google Scholar 

  • Lerman, J.: [3] The contribution of triiodothyronine to thyroid physiology. J. Clin. Endocrin. 14, 690 (1954).

    CAS  Google Scholar 

  • Lindeboom, G. A., Tj. E. Hoodendijk-Van Dort and J. De Jong: [1] Blood levels of I131 after tracer doses in euthyroids and in untreated thyrotoxicosis. Acta med. scand. (Stockh.) 40, 477 (1955).

    Google Scholar 

  • Lindeboom, G. A., Tj. E. Hoodendijk-Van Dort and J. De Jong: [2] Blood levels of I131 after tracer doses in patients with thyrotoxicosis treated with radio-iodine. Acta med. scand. (Stockh.) 40, 487 (1955).

    Google Scholar 

  • Lipner, H. J., S. B. Barker and T. Winnick: The distribution of thyroxine in rat liver cell fractions. Endocrinology (Springfield, Ill.) 51, 406 (1952).

    CAS  Google Scholar 

  • Lipschitz, W.: [1] Die Bedeutung des inneren Kreislaufs für Krystalloide, speziell das Jodion. Klin. Wschr. 1929, 116.

    Google Scholar 

  • Lipschitz, W.: [2] Differenzierung des Thyroxinjods vom anorganischen Jod durch die Membranen des lebenden Organismus. Klin. Wschr. 1930, 642.

    Google Scholar 

  • Lowrey, G. H., W. H. Beierwaltes, I. Lampe and H. J. Gomberg: Radioiodine uptake curves in humans. II. Studies in children. Pediatrics 4, 627 (1949).

    Google Scholar 

  • Ludwig, W., u. P. V. Mutzenbecher: Die Darstellung von Thyroxin, Monojodtyrosin und Dijodtyrosin aus jodiertem Eiweiß. Z. physiol. Chem. 258, 195 (1939).

    CAS  Google Scholar 

  • Ltjellen, T. J., F. R. Keating, Jr., M. M. D. Williams, J. Berkson, M. H. Power and W. M. McConahey: Relative measurement in vivo of accumulation of radioiodide by the human thyroid gland: comparison with radioactivity in peripheral tissue. J. Clin. Invest. 28, 207 (1949).

    Google Scholar 

  • Macgregor, A. G.: Radioactive iodine in the diagnosis of thyrotoxicosis. Brit. J. Radiol. 23, 550 (1950).

    PubMed  CAS  Google Scholar 

  • Macgregor, A. G., H. Miller, P. J. Blanley and W. S. Whimster: Diagnosis of thyrotoxicosis by a simple out-patient radioactive iodine technique. Brit. Med. J. 1953, 21.

    Google Scholar 

  • Macintyre, W. J.: A scintillation counter for measurement of iodine-131 uptake in the thyroid gland. Proc. Soc. Exper. Biol. a. Med. 75, 561 (1950).

    CAS  Google Scholar 

  • Mackenzie, C. G., and J. B. Mackenzie: Effect of sulfonamides and thioureas on the thyroid gland and basal metabolism. Endocrinology (Springfield, Ill.) 32, 185 (1943).

    CAS  Google Scholar 

  • Maclagan, N. F., W. E. Sprott and J. H. Wilkinson: Effect of 3:5:3’-l-triiodothyronine and certain anti-thyroxine substances on the oxygen consumption of mice. Lancet 1952 II, 915.

    Google Scholar 

  • Mallet, L.: Recherches d’une thyroide aberrante a L’aide de 1’iode radio-actif 131. J. Radiol. Electrol. 31, 703 (1950).

    CAS  Google Scholar 

  • Maloof, F., and E. M. Chapman: Response to radioactive iodine therapy in hyperthyroidism, with special reference to cardiac problems. J. Clin. Endocrin. 11, 1296 (1951).

    CAS  Google Scholar 

  • Maloof, F., B. M. Dobyns and A. L. Vickery: The effects of various doses of radioactive iodine on the thyroid of the rat. Endocrinology (Springfield, Ill.) 50, 612 (1952).

    CAS  Google Scholar 

  • Man, E. B., D. M. Kydd and J. P. Peters: Butanol-extractable iodine of serum. J. Clin. Invest. 30, 531 (1951).

    PubMed  CAS  Google Scholar 

  • Mann, W., C. P. Leblond and S.L. Warren: Iodine metabolism of the thyroid gland. J. of Biol. Chem. 142, 905 (1942).

    CAS  Google Scholar 

  • Marinelli, L. D., and R. F. Hill: In Conference Report BLN-C-5, S. 98, Brookhaven National Laboratory 1948.

    Google Scholar 

  • Marinelli, L. D., E.H. Qttimby and G. J. Hine: Dosage determinations with radioactive isotopes. II- Practical considerations in therapy and protection. Amer. J. Roentgenol. 59, 260 (1948).

    CAS  Google Scholar 

  • Marinoni, V.: [1] Fissazione della J131 nella tiroide fetale umana. (Descrizione di un caso). Fol. endocrinol. (Pisa) 4, 637 (1951).

    CAS  Google Scholar 

  • Marinoni, V.: [2] La jodio radioattivo (J131) nella ricerca del tessuto tiroideo in sede anomale. Giorn. Clin. Med. 33, 862 (1952).

    CAS  Google Scholar 

  • Martin, J. H.: Radiation doses received by the skin of a patient during routine diagnostic x-ray examinations. Brit. J. Radiol. 20, 279 (1947).

    PubMed  CAS  Google Scholar 

  • Mason, A. S., and R. Oliver: Urinary excretion of radioactive iodine as a diagnostic aid in thyroid disorders. Lancet 1949 II, 456.

    Google Scholar 

  • Mason, E. E., and H. S. Bloch: Gastric secretion of iodide at low serum iodide levels. Proc. Soc. Exper. Biol. a. Med. 73, 488 (1950).

    CAS  Google Scholar 

  • Maurer, W., u. E. R. Müller: Zur Frage der Transportfunktion einzelner Serum-Eiweiß- Fraktionen für die organischen Jodverbindungen des Serums. (Papierelektrophoretische Untersuchung von J131-markierten Seren bei niedriger und hoher Strahlenbelastung der Schilddrüse.) Biochem. Z. 324, 325 (1953).

    PubMed  CAS  Google Scholar 

  • Maurer, W. u. L. Reichenbach: Über die Bindung des organischen Jods im Serum an einzelne Serum- Eiweißfraktionen. Naturwiss. 39, 261 (1952).

    CAS  Google Scholar 

  • McArthur, J. W., R. W. Rawson, R. G. Fluharty and J. H. Means: The urinary excretion of radioactive iodine as an aid in diagnosis of hyperthyroidism. Ann. Int. Med. 29, 229 (1948).

    PubMed  CAS  Google Scholar 

  • McConahey, W. M., and F. R. Keating, Jr.: Radioiodine studies in thyroiditis. J. Clin. Endocrin. 11, 1116 (1951).

    CAS  Google Scholar 

  • McConahey, W. M., F. R. Keating, Jr. and M. H. Power: [1] The behavior of radioiodine in the blood. J. Clin. Invest. 28, 191 (1949).

    CAS  Google Scholar 

  • McConahey, W. M., F. R. Keating, Jr. and M. H. Power: [2] An estimation of the renal and extrarenal clearance of radioiodide in man. J. Clin. Invest. 30, 778 (1951).

    PubMed  CAS  Google Scholar 

  • McCullagh, E. P., A. Gold and J. B. R. Mckendry: Radioactive iodine uptake in the hypermetabolism of acromegaly. J. Clin. Endocrin. 10, 687 (1950).

    CAS  Google Scholar 

  • McGinty, D. A., R. W. Rawson, R. G. Fluharty, M. Wilson, C. Riddell and H. Yee: The effect of certain goitrogenic drugs on the absorption of radioactive iodine by the thyroid gland. II. J. Pharmakol. a. Exper. Ther. 93, 246 (1948).

    CAS  Google Scholar 

  • McGinty, D. A. and E. A. Sharp: Effect of iodine intake on thyroid iodine distribution and thyroid weight of rats treated with thiouracil and other goitrogens. J. Clin. Endocrin. 6, 473 (1946).

    Google Scholar 

  • Mcgirr, E. M., and J. H. Hutchison: Radioactive-iodine studies in non-endemic goitrous cretinism. Lancet 1953 I, 1117.

    Google Scholar 

  • Means, J. H.: The thyroid hormone. Certain aspects of its elaboration in the body, the significance of its structure, and of its action on end organs. Bull. Johns Hopkins Hosp. 89, 90 (1951).

    PubMed  CAS  Google Scholar 

  • Meissner, J., J. Kracht u. N. Diller: Nachweis der Schreckthyreotoxikose des Wildkaninchens mit radioaktivem Jod. Arch, exper. Path. u. Pharmakol. 216, 424 (1952).

    CAS  Google Scholar 

  • Meites, J., and L. F. Wolterink: Uptake of radioactive iodine by the thyroids of underfed rats. Science (Lancaster, Pa.) 111, 175 (1950).

    CAS  Google Scholar 

  • Meyer Zum Gottesberge, A., u. W. Maurer: Funktionsprüfung einer Zungenstruma mit radioaktivem Jod131. HNO-Ratgeber ärztl. Praxis 2, 274 (195lJ.

    Google Scholar 

  • Middlesworth, L. Van., C. E. Nürnberger and A. Lipscomb: Simplified sensitive test for thyroid function, using protein-bound I131. J. Clin. Endocrin. 14, 1056 (1954).

    Google Scholar 

  • Miller, E. R., M. E. Dailey, A. V. Holmes, G. L. Alexander and G. E. Sheline: Studies with radioiodine. I. Function and rate of I131 uptake of thyroid. Radiology 57, 37 (1951).

    CAS  Google Scholar 

  • Money, W. L., J. E. Rall and R. W. Rawson: The effect of low iodine diet on thyroid function in rat. J. Clin. Endocrin. 12, 1495 (1952).

    CAS  Google Scholar 

  • Money, W. L. and R. W. Rawson: The experimental production of thyroid tumors in the male rat. Transact. Amer. Assoc. Study Goiter 1947, 171.

    Google Scholar 

  • Morgans, M. E., A. K. Oldham and W. R. Trotter: The effect of exogenous thyroxine on radioiodine uptake in normal subjects and in cases of thyrotoxicosis in remission. J. of Endocrin. 8, 250 (1952).

    CAS  Google Scholar 

  • Morgans, M. E. and W. R. Trotter: Treatment of thyrotoxicosis with potassium Perchlorate. Lancet 1954 I, 749.

    Google Scholar 

  • Morris, H. P., A. J. Dalton and C. D. Green: Malignant thyroid tumors occuring in the mouse after prolonged hormonal imbalance during the ingestion of thiouracil. J. Clin. Endocrin. 11, 1281 (1951).

    CAS  Google Scholar 

  • Morton, M. E.: Measurement of thyroxine synthesis with I131. A test for evaluation of thyroid function in equivocal states. Calif. Med. 78, 277 (1953).

    PubMed  CAS  Google Scholar 

  • Morton, M. E. and I. L. Chaikoff: The formation in vitro of thyroxine and diiodotyrosine in thyroid tissue with radioactive iodine as indicator. J. of Biol. Chem. 147, 1 (1943).

    CAS  Google Scholar 

  • Morton, M. E., I. L. Chaikoff and S. Rosenfeld: Inhibiting effect of inorganic iodide on the formation in vitro of thyroxine and diiodotyrosine by surviving thyroid tissue. J. of Biol. Chem. 154, 381 (1944).

    CAS  Google Scholar 

  • Morton, M. E., R. E. Ottoman and R. E. Peterson: Thyroid uptake measured one hour after small doses of radioiodine. J. Clin. Endocrin. 11, 1572 (1951).

    CAS  Google Scholar 

  • Morton, M. E., I. Perlman, E. Anderson and I. L. Chaikoff: Radioactive iodine as an indicator of the metabolism of iodine. V. The effects of hypophysectomy on the distribution of labeled thyroxine and diiodotyrosine in thyroid gland and plasma. Endocrinology (Springfield, Ill.) 30, 495 (1942).

    Google Scholar 

  • Morton, M. E. and I. L. Chaikoff: Radioactive iodine as an indicator of the metabolism of iodine. III. The effect of thyrotropic hormone on the turnover of thyroxine and diiodotyrosine in the thyroid gland and plasma. J. of Biol. Chem. 140, 603 (1941).

    CAS  Google Scholar 

  • Murray, M. M., and E. E. Pochin: Thyroid uptake of iodine from ingested iodate in man. J. of Physiol. 114, 6P (1951).

    Google Scholar 

  • Mutzenbecher, P. V.: Über die Bildung von Thyroxin aus Dijodtyrosin. Z. physiol. Chem. 261, 253 (1939).

    Google Scholar 

  • Muylder, E. De, et J. Maisin: Valeur comparative du métabolisme de base et de l’excrétion urinaire d’iode marqué comme test de la fonction thyroidienne. Ann. d’Endocrin. 12, 1098 (1951).

    Google Scholar 

  • Myant, N. B.: [1] Comparison of the effect of thiouracil, thyroxine and cortisone on the thyroid function of rabbits. J. of Physiol. 120, 288 (1953).

    CAS  Google Scholar 

  • Myant, N. B.: [2] Early effects of radioiodine on human thyroid function. Clin. Sci. 12, 235 (1953).

    PubMed  CAS  Google Scholar 

  • Myant, N. B., B. D. Corbett, A. J. Honour and E. E. Pochin: Distribution of radioiodide in man. Clin. Sci. 9, 405 (1950).

    CAS  Google Scholar 

  • Myant, N. B., A. J. Honour and E. E. Pochin: The estimation of radioiodine in the thyroid gland of living subjects. Clin. Sci. 8, 135 (1949).

    PubMed  CAS  Google Scholar 

  • Myant, N. B. and E. E. Pochin: The metabolism of radiothyroxine. Clin. Sci. 9, 421 (1950).

    CAS  Google Scholar 

  • Myant, N. B., E. E. Pochin and E. A. Goldie: The plasma iodide clearance rate of the human thyroid. Clin. Sci. 8, 109 (1949).

    PubMed  CAS  Google Scholar 

  • Nachman, H. M., V. Crawford and I. A. Bigger: Radioactive iodine (I131) in the diagnosis of lingual thyroid. J. Amer. Med. Assoc. 140, 1154 (1949).

    CAS  Google Scholar 

  • Nadler, N. J., C. P. Leblond and R. Bogoroch: The rate of iodine metabolism by the thyroid follicle as a function of its size. Endocrinology (Springfield, Ill.) 54, 154 (1954).

    CAS  Google Scholar 

  • Nelson, N., E. D. Palmes, C. R. Park, P. P. Weymouth and W. B. Bean: The absorption, excretion, and physiological effect of iodine in normal human subjects. J. Clin. Invest. 26, 301 (1947).

    CAS  Google Scholar 

  • Nitowsky, H. M., and T. T. Puck: A modified radioiodine test for thyroid function. J. Labor, a. Clin. Med. 39, 824 (1952).

    CAS  Google Scholar 

  • Noble, M. J. D., and S. Rowlands: The utilization of radio-iodine during pregnancy. J. Obstetr. Gynaec. Brit. Emp. 60, 892 (1953).

    CAS  Google Scholar 

  • Nodine, J. H., W. H. Perloff, D. De Albuquerque, L. Perczek and B. Channick: The diphasic character of thyroidal I131 clearance. J. Clin. Endocrin. 15, 347 (1955).

    CAS  Google Scholar 

  • Oddie, T. H.: An analysis of radioiodine uptake and excretion curves. Brit. J. Radiol. 22, 261 (1949).

    PubMed  CAS  Google Scholar 

  • Oddie, T. H., I. Meschan and J. Wortham: [1] Thyroid function assay with radioiodine. I. Physical basis of study of early phase of iodine metabolism and iodine uptake. J. Clin. Invest. 84, 95 (1955).

    Google Scholar 

  • Oddie, T. H., I. Meschan and J. Wortham: [2] Thyroid function assay with radioiodine. II. Routine calculation of thyroidal and renal rate factors. J. Clin. Invest. 34, 106 (1955).

    PubMed  CAS  Google Scholar 

  • Oddie, T. H. and R. K. Scott: [1] External measurement of radio-iodine in the thyroid gland. Brit. J. Radiol. 22, 698 (1949).

    PubMed  CAS  Google Scholar 

  • Oddie, T. H. and R. K. Scott: [2] Results of uptake and excretion test with radio-iodine. Brit. J. Radiol. 23, 349 (1950).

    Google Scholar 

  • Oliver, R., and F. Ellis: Radioactive iodine studies in non-endemic goitrous cretinism. Lancet 1953 II, 138.

    Google Scholar 

  • Owen, C. A. Jr., and M.H. Power: Distribution of iodide between cells and plasma as measured by means of radioactive iodide. J. of Biol. Chem. 200, 111 (1953).

    CAS  Google Scholar 

  • Pahaut, J., J. Govaerts and P. Bonhomme: Effect of diuresis on uptake of radioiodine (I131) by the thyroid. Nature (London) 172, 545 (1953).

    CAS  Google Scholar 

  • Papper, S., B. A. Burrows, S. H. Ingbar, J. H. Sisson and J. F. Ross: The effects of 1-thyroxine sodium on nontoxic goiter, on myxedema and on the thyroid uptake of iodine. New Engl. J. Med. 247, 897 (1952).

    CAS  Google Scholar 

  • Pearson, J. D., and N. Veall: Persönliche Mitteilung.

    Google Scholar 

  • Perlman, I., M. E. Morton and I. L. Chaikoff: Radioactive iodine as an indicator of the metabolism of iodine. II. The rate of formation of thyroxine and diiodotyrosine by the intact normal thyroid gland. J. of Biol. Chem. 139, 449 (1941).

    CAS  Google Scholar 

  • Perlmutter, M., and P. H. Forsham: Thyroid uptake of radioactive iodine in the normal and hypometabolic human. J. Clin. Endocrin. 8, 610 (1948).

    CAS  Google Scholar 

  • Perlmutter, M. and M. Mufson: Inhibition of a cervical thyroid gland by a functioning struma ovarii. J. Clin. Endocrin. 11, 621 (1951).

    CAS  Google Scholar 

  • Perlmutter, M. and D. S. Riggs: Thyroid collection of radioiodide and serum protein-bound iodine concentration in senescence, in hypothyroidism and in hypopituitarism. J. Clin. Endocrin. 9, 430 (1949).

    CAS  Google Scholar 

  • Perlmutter, M., S. L. Slater and J. Attie: Method for preoperative differentiation between the benign and the possibly malignant solitary nontoxic thyroid nodule. J. Clin. Endocrin. 14, 672 (1954).

    CAS  Google Scholar 

  • Perlmutter, M., S. Weisenfeld and M. Mufson: Comparison of a single G-M tube method and a multitube methode of assaying I131 uptake by the human thyroid. J. Clin. Endocrin. 11, 1012 (1951).

    CAS  Google Scholar 

  • Perlmutter, M., S. Weisenfeld, M. Mufson, S. L. Slater and E. Z. Wallace: A study of the mechanism of the inhibition of the thyroid gland induced by ingestion of thyroid substance. J. Clin. Endocrin. 12, 208 (1952).

    CAS  Google Scholar 

  • Perloff, W. H., L.M. Levy and A. Despopoulos: The use of thyrotropic hormone (TSH) in the diagnosis of myxedema. J. Clin. Endocrin. 11, 1495 (1951).

    CAS  Google Scholar 

  • Perry, W. F., and J. P. Gemelli The use of radioactive iodine in the diagnosis of hyper- and hypothyroidism. Canad. Med. Assoc. J. 62, 484 (1950).

    PubMed  CAS  Google Scholar 

  • Perry, W. F. and J. F. Hughes: The urinary excretion and thyroid uptake of iodine in renal disease. J. Clin. Invest. 31, 457 (1952).

    PubMed  CAS  Google Scholar 

  • Pfeifer, W.: Kritisches zur Radiotestung und Behandlung von Schilddrüsenerkrankungen. Med. Klin. 1954, 1749.

    Google Scholar 

  • Pickering, D. E., and E. R. Miller: Thyrotropic hormone in infants and children. Differentiation between primary and hypopituitary hypothyroidism. Amer. J. Dis. Childr. 85, 135 (1953).

    CAS  Google Scholar 

  • Pitt-Rivers, R.: [1] Mode of action of antithyroid compounds. Physiologic. Rev. 30,194(1950).

    Google Scholar 

  • Pitt-Rivers, R.: [2] Persönliche Mitteilung.

    Google Scholar 

  • Pitt-Rivers, R. and W. R. Trotter: The site of accumulating of iodide in the thyroid of rats treated with thiouracil. Lancet 1953 II, 918.

    Google Scholar 

  • Pochin, E. E.: [1] Investigation of thyroid function and disease with radioactive iodine I131. Lancet 1950 II, 41.

    Google Scholar 

  • Pochin, E. E.: [2] The iodine uptake of the human thyroid throughout the menstrual cycle and in pregnancy. Clin. Sci. 11, 441 (1952).

    PubMed  CAS  Google Scholar 

  • Potts, A. M., R. A. Shipley, J. P. Storaasli and H. L. Friedell: The effect of thyroid secretory activity on the distribution of radioiodine in plasma. J. Labor, a. Clin. Med. 34, 1520 (1949).

    CAS  Google Scholar 

  • Purves, H. D., and W. E. Griesbach: [1] Studies on experimental goiter. VII. Thyroid carcinomata in rats treated with thiourea. Brit. J. Exper. Path. 27, 294 (1946).

    CAS  Google Scholar 

  • Purves, H. D., and W. E. Griesbach: [2] The effect of thyroid administration on the thyrotropic activity of the rat pituitary. Endocrinology (Springfield, Ill.) 39, 274 (1946).

    CAS  Google Scholar 

  • Querido, A., and J. B. Stanbury: The response of the thyroid gland to thyrotropic hormone as an aid in the differential diagnosis of primary and secondary hvpothyroidism. J. Clin. Endocrin. 10, 1192 (1950).

    CAS  Google Scholar 

  • Quimby, E. H., and S. C. Werker: Late radiation effects in roentgentherapy for hyperthyroidism. J. Amer. Med. Assoc. 140, 1046 (1949).

    Google Scholar 

  • Quimby, E. H., S. C. Werker and C. Schmidt: Influence of age, sex and season upon radioiodine uptake by the human thyroid. Proc. Soc. Exper. Biol. a. Med. 75, 537 (1950).

    CAS  Google Scholar 

  • Raben, M. S.: The paradoxical effects of thiocyanate and thyrotropin on the organic binding of iodine by the thyroid in the presence of large amounts of iodide. Endocrinology (Springfield, Ill.) 45, 296 (1949).

    CAS  Google Scholar 

  • Raben, M. S., and E. B. Astwood: The use of radioiodine in physiological and clinical studies on the thyroid gland. J. Clin. Invest. 28, 1347 (1949).

    PubMed  CAS  Google Scholar 

  • Rall, J. E.: Iodine compounds in the blood and urine of man. J. Clin. Endocrin. 10, 996 (1950).

    CAS  Google Scholar 

  • Rall, J. E., M. H. Power and A. Albert: Distribution of radioiodine in erythrocytes and plasma in man. Proc. Soc. Exper. Biol. a. Med. 74, 460 (1950).

    CAS  Google Scholar 

  • Rall, J. E., M. S. Sonenberg, J. Robbins, R. Lazerson and R. W. Rawson: The blood level as a guide to therapy with radioiodine. J. Clin. Endocrin. 13, 1369 (1953).

    CAS  Google Scholar 

  • Randall, R. V., and A. Albert: The effect of hypophysectomy on the uptake of radioactive iodine by the thyroid gland of the rat. Endocrinology (Springfield, Ill.) 48, 327 (1951).

    CAS  Google Scholar 

  • Randall, R. V., N. Lorenz and A. Albert: The effect of hypophysectomy on the biological decay of thyroidal iodine. Endocrinology (Springfield, Ill.) 48, 339 (1951).

    CAS  Google Scholar 

  • Rawson, R. W.: Persönliche Mitteilung.

    Google Scholar 

  • Rawson, R. W., R. D. Evans, J. H. Means, W. Peacock, J. Lerman and R. E. Cortell: The action of thiouracil upon the thyroid gland in Graves’ disease. J. Clin. Endocrin. 4, 1 (1944).

    CAS  Google Scholar 

  • Rawson, R. W., S. Hertz and J. H. Means: Thiocyanate goiter in man. Ann. Int. Med. 19, 829 (1943).

    CAS  Google Scholar 

  • Rawson, R. W., D. A. McGinty and W. Peacock: The comparative effect of various goitrogenic agents on the collection of radioactive iodine by the thyroid in rats and chicks. Endocrinology (Springfield, Ill.) 39, 78 (1946).

    Google Scholar 

  • Rawson, R. W., D. A. McGinty, W. Peacock, P. Merrill, M. Wilson and H. Lockhardt: The effect of certain goitrogenic drugs on the absorption of radioactive iodine by the thyroid gland of rats and chicks. I. J. Pharmacol, a. Exper. Ther. 93, 240 (1948).

    CAS  Google Scholar 

  • Rawson, R. W., and W. L. Money: Physiologic reactions of the thyroid stimulating hormone. Recent Progr. in Hormone Res. 4, 397 (1949).

    Google Scholar 

  • Rawson, R. W., J. E. Rall and W. Peacock: Limitations and indications in the treatment of cancer of the thyroid with radioactive iodine. J. Clin. Endocrin. 11, 1128 (1951).

    CAS  Google Scholar 

  • Rawson, R. W., J. E. Rall, O.H.Pearson, J. Robbins, H. F. Poppell and C. D. West: 1-Triiodothyronine versus 1-thyroxine. A comparison of their metabolic effects in human myxedema. Amer. J. Med. Sci. 226, 405 (1953).

    CAS  Google Scholar 

  • Rawson, R. W., J. F. Tannheimer and W. Peacock: The uptake of radioactive iodine by the thyroids of rats made goiterous by potassium thiocyanate and bv thiouracil. Endocrinology (Springfield, Ill.) 34, 245 (1944).

    CAS  Google Scholar 

  • Recant, L., and D. S. Riggs: Thyroid function in nephrosis. J. Clin. Invest. 31, 789 (1952).

    PubMed  CAS  Google Scholar 

  • Reid, A. F., and J. Sorenson: Effective thyroid depth and compensating measurements for iodine uptake determination. Radiology 58, 390 (1952).

    PubMed  CAS  Google Scholar 

  • Reilly, W. A., and D. I. Bayer: The value of the measurement of thyroid uptake and urinary excretion of I131 in assessing thyroid function of normal and congenitally hypothyroid children. J. of Pediatr. 40, 714 (1952).

    CAS  Google Scholar 

  • Reiss, M., C. P. Haigh, R. E. Hemphill, R. Maggs, J. M. Reiss and S. Smith: Studies of the human thyroid function, measured by radio-iodine and its relation to the basal metabolic rate. J. of Endocrin. 8, 1 (1952).

    CAS  Google Scholar 

  • Reiss, M., R. E. Hemphill, R. Maggs, C. P. Haigh and J. M. Reiss: The significance of the thyroid in psychiatric illness and treatment. Brit. Med. J. 1953, 906.

    Google Scholar 

  • Reiss, M., R. E. Hemphill, R. Maggs, S.Smith, C. P. Haigh and J. M. Reiss: Thyroid activity in mental patients; evaluation by radioactive tracer methods. Brit. Med. J. 1953, 1181.

    Google Scholar 

  • Reiss, M., R. E. Hemphill, B.M. Murphy, J. M. Halkerston and F. E. Badrick: Investigations of human thyroid function with the use of small doses of radioactive iodine, and the effect of thyrotrophs hormone on I131 uptake and excretion. J. of Endocrin. 6, 235 (1949).

    CAS  Google Scholar 

  • Reynolds, L., K. E. Corrigan and H. S. Hayden: Detection of concealed thyroid disease by tracer technique. J. Amer. Med. Assoc. 151, 368 (1953).

    CAS  Google Scholar 

  • Richards, C. E., R. J. Brockhtjrst and T. H. Coleman: Thiocyanate goiter with myxedema. Report of two cases. J. Clin. Endocrin. 9, 446 (1949).

    CAS  Google Scholar 

  • Riggs, D. S.: [1] Elevation of serum protein-bound iodine after large doses of radioactive iodine. Federat. Proc. 7, 251 (1948).

    CAS  Google Scholar 

  • Riggs, D. S.: [2] Quantitative aspects of iodine metabolism in man. Pharmacol. Rev. 4, 284 (1952).

    PubMed  CAS  Google Scholar 

  • Riggs, D. S., D. F. Gildea, E. B. Man and J. B. Peters: Blood iodine in patients with thyroid disease. J. Clin. Invest. 20, 345 (1941).

    PubMed  CAS  Google Scholar 

  • Riggs, D. S., P. H. Lavietes and E. B. Man: Investigations on the nature of blood iodine. J. of Biol. Chem. 143, 363 (1942).

    CAS  Google Scholar 

  • Robbins, J.: [1] Thyroglobulin in serum after I131 therapv. I. Salting out. J. of Biol. Chem. 208, 377 (1954).

    CAS  Google Scholar 

  • Robbins, J.: [2] Persönliche Mitteilung.

    Google Scholar 

  • Robbins, J., M. L. Petermann and J. E. Rall: Thyroglobulin in serum after I131 therapy. II. Sedimentation in the ultracentrifuge. J. of Biol. Chem. 208, 387 (1954).

    CAS  Google Scholar 

  • Robbins, J. and J. E. Rall: Zone electrophoresis in filter paper of serum I131 after radioiodide administration. Proc. Soc. Exper. Biol. a. Med. 81, 530 (1952).

    CAS  Google Scholar 

  • Robbins, J., D. V. Becker and R. W. Rawson: The nature of the serum iodine after large doses of I131. J. Clin. Endocrin. 12, 856 (1952).

    CAS  Google Scholar 

  • Robbins, J. and M. L. Petermann: Protein-binding of thyroxine in normal and nephrotic serum. J. Clin. Invest. 33, 959 (1954).

    Google Scholar 

  • Robbins, J., M. L. Petermann, J. B. Trunnell and R. W. Rawson: The effect of thyroid-stimulating hormone in acute thyroiditis. J. Clin. Endocrin. 10, 1106 (1950).

    Google Scholar 

  • Roche, J., G. H. Deltour, S. Lissitzky et R. Michel: Sur les constituants iodés de la thyro- globuline marquée et leur libération au cours de l’hydrolyse trypsique. C. r. Soc. Biol. (Paris) 144, 1321 (1950).

    CAS  Google Scholar 

  • Roche, J., G. H. Deltour, R. Michel et S. Lissitzky: Sur la protéolyse thyroidienne de la thyroglobuline radioactive. C. r. Soc. Biol. (Paris) 144, 1647 (1950).

    CAS  Google Scholar 

  • Roche, J., M. Jtjtisz, S. Lissitzky et R. Michel: Chromatographie quantitative des acides aminés iodés radioactifs de la thyroglobuline marquée. Biochim. et Biophysica Acta 7, 257 (1951).

    CAS  Google Scholar 

  • Roche, J., S. Lissitzky et R. Michel: [1] Sur la triiodothyronine, produit intermédiaire de la transformations de la diiodothyronine en thyroxine. C. r. Acad. Sci. (Paris) 234, 997 (1952).

    CAS  Google Scholar 

  • Roche, J., S. Lissitzky et R. Michel: [2] Sur la triiodothyronine et sur sa présence dans les proteines thyroidiennes. Ann. pharm, franç. 10, 166 (1952).

    CAS  Google Scholar 

  • Roche, J., S. Lissitzky et R. Michel: [3] Sur la présence de triiodothyronine dans la thyroglobuline. C. r. Acad. Sci. (Paris) 234, 1223 (1952).

    Google Scholar 

  • Roche, J., O. Michel, G. H. Deltour et R. Michel: Sur la thyroglobuline humaine marquée par l’iode radioactif, à l’état normal et dans la maladie de Basedow. Ann. d’Endocrin. 13, 1 (1952).

    CAS  Google Scholar 

  • Roche, J., O. Michel, R. Michel and J. Tata: On the products of hepatic and renal elimination of thyroxine and triiodothyronine labelled with iodine-131. A. E. R. E. Harwell Radioisotope Conference 1954. Vol. I., S. 325. London: Butterworths 1954.

    Google Scholar 

  • Roche, J., R. Michel, S. Lissitzky et O. Michel: Sur la formation d’iodures à partir de la diiodo- tyrosine dans le corps thyroide et sur leur réutilisation. C. r. Acad. Sci. (Paris) 232, 2148 (1951).

    CAS  Google Scholar 

  • Roche, J., R. Michel, O. Michel, G. H. Deltour et S. Lissitzky: Thyroglobuline marquée on artificiellement iodée sans dénaturation. Formation dans des conditions experimentales diverses et propriétés. Biochim. et Biophysica Acta 6, 572 (1951).

    CAS  Google Scholar 

  • Roche, J., R. Michel, O. Michel, et S. Lissitzky: [1] Déshalogénation enzymatique des acides aminés iodés dans le thyroide et thyroxinémie. C. r. Soc. Biol. (Paris) 145, 288 (1951).

    CAS  Google Scholar 

  • Roche, J., R. Michel, O. Michel, et S. Lissitzky: [2] Sur la déshalogénation enzymatique des iodotyrosines par le corps thyroide et sur son rôle physiologique. Biochim. et Biophysica Acta 9, 161 (1952).

    CAS  Google Scholar 

  • Rollman, H. S., and D. W. Petit: Plasma levels of radioactive iodine (I131) in human tracer studies. Proc. Soc. Exper. Biol, a, Med. 72, 474 (1949).

    CAS  Google Scholar 

  • Rollman, H. S., D. W. Petit and P. Starr: Serial observations of I131 levels in the plasma as an aid to the diagnosis of hypothyroidism. J. Labor, a. Clin. Med. 39, 697 (1952).

    CAS  Google Scholar 

  • Rose, G., and E. W. Emery: Effects of solution composition on a G-M counter for liquid samples. Nucleonics 9, 5 (1951).

    PubMed  CAS  Google Scholar 

  • Rosenberg, I.N.: [1] The nature of the circulating thyroid hormone in Graves’ disease. J. Clin. Invest. 30, 1 (1951).

    PubMed  CAS  Google Scholar 

  • Rosenberg, I.N.: [2] Column chromatographv of thvroid gland hydrolysates. J. Clin. Endocrin. 11, 1063 (1951).

    CAS  Google Scholar 

  • Roswit, B., J. A. Rosenkrantz, J. Sorrentino, R. Yalow and I. Berlin: Evaluation of diagnostic methods in diseases of thyroid function, with particular reference to radioiodine tracer tests. Amer. J. Med. Sci. 223, 229 (1952).

    PubMed  CAS  Google Scholar 

  • Rotblat, J., and G. M. Owen: The biological half-life of 131I in thyroid carcinoma. A. E. R. E. Harwell Radioisotope Conference 1954. Vol. I. S. 68. London: Butterworths 1954.

    Google Scholar 

  • Rowlands, E. N., D. A. W. Edwards and A. J. Honour: Study of effect of Perchlorate and thiocyanate on salivary iodide. Clin. Sci. 12, 399 (1953).

    PubMed  CAS  Google Scholar 

  • Saegesser, M.: Jodfraktionen des Kropfes und funktionelle Minderwertigkeit. Mitt. Grenzgeb. Med. u. Chir. 43, 55 (1932/34).

    Google Scholar 

  • Salter, W. T.: The metabolic circuit of the thvroid hormone. Ann. N. Y. Acad Sci. 50, 358 (1949).

    PubMed  CAS  Google Scholar 

  • Salter, W. T. and Mac A. W. Johnston: Tracing the thvroid hormone in peripheral tissues. J. Clin. Endocrin. 8, 911 (1948).

    CAS  Google Scholar 

  • Salter, W. T., G. Karandikar and P. Block: Organic and inorganic iodine: their reciprocal metabolic fates. J. Clin. Endocrin. 9, 1080 (1949).

    CAS  Google Scholar 

  • Salzmann, F., u. H. Vetter: Unveröffentlichte Beobachtungen.

    Google Scholar 

  • Schachner, H., A. L. Franklin and I. L. Chaikoff: [1] The effect of cytochrome oxydase inhibitors on the formation of thyroxine and diiodotyrosine by thyroid tissue with radioactive iodine as indicator. J. of Biol. Chem. 151, 191 (1943).

    CAS  Google Scholar 

  • Schachner, H., A. L. Franklin and I. L. Chaikoff: [2] On the in vitro accumulation of inorganic iodide by surviving thyroid tissue with radioactive iodine as indicator. Endocrinology (Springfield, Ill.) 34, 159 (1944).

    CAS  Google Scholar 

  • Schiff, L., C. D. Stevens, W. E. Molle, H. Steinberg, C. W. Kumpe and P. Stewart: Gastric (and salivary) excretion of radioiodine in man (preliminary report). J. Nat. Cancer Inst. 7, 349 (1947).

    PubMed  CAS  Google Scholar 

  • Schilling, J. A., J. W. Karr and J. B. Hursh: The treatment of a lingual thyroid with radioactive iodine. Surgery 27, 130 (1950).

    PubMed  CAS  Google Scholar 

  • Schmeiser, K.: Nachweis radioaktiver Isotope; in Künstliche radioaktive Isotope in Physiologie, Diagnostik und Therapie. Berlin-Göttingen-Heidelberg: Springer-Verlag 1953.

    Google Scholar 

  • Schneeberg, N. G., W. H. Perloff and L. M. Levy: Diagnosis of equivocal hypothyroidism using thyrotrophs hormone (TSH). J. Clin. Endocrin. 14, 223 (1954).

    CAS  Google Scholar 

  • Schneeberg, N. G., W. H. Perloff, L. M. Levy, W. Serber, T. E. Sopp and L. Stanton: An evaluation of the radioiodine concentration test in the study of thyroid disease. Radiology 56, 869 (1951).

    PubMed  CAS  Google Scholar 

  • Schoenheimer, R.: The Dynamic State of Body Constituents. Cambridge, Mass.: Harvard Univ. Press 1942.

    Google Scholar 

  • Schuchter, A., u. W. Bartsch: Über die Beeinflussung der Schilddrüsenfunktion durch Tumore im Bereich der Sella und des Zwischenhirns. Ärztl. Wschr. 1952, 939.

    Google Scholar 

  • Schultz, A. L., and L. Zieve: Clinical value of the butanol extractable (thyroxine) I131 in the diagnosis of hyperthyroidism. J. Labor, a. Clin. Med. 42, 949 (1953).

    Google Scholar 

  • Scott, K. G., J. G. Reavis, W. W. Saunders and W. E. White: The use of the I131 red cell plasma ratio as a measure of thyroid function. Proc. Soc. Exper. Biol. a. Med. 76, 592 (1951).

    CAS  Google Scholar 

  • Seed, L., B. Jaffe and C. Baumeister: The tracer dose of radioactive iodine in the diagnosis of thyroid disease. J. Clin. Endocrin. 11, 1143 (1951).

    CAS  Google Scholar 

  • Seidlin, S. M., E. Oshry, I. Rossman and L. Leiter: Radioiodine uptake by the thyroid as an aid in differential diagnosis. J. Clin. Endocrin. 8, 609 (1948).

    CAS  Google Scholar 

  • Selenkow, H. A., and S. P. Asper: The effectiveness of triiodothyronine or thyroxine administered orally in the treatment of myxedema. J. Clin. Endocrin. 15, 285 (1955).

    CAS  Google Scholar 

  • Sexton, D. L., and R. Mack: Cretinism, with or without goiter, in 5 of 10 siblings. J. Clin. Endocrin. 14, 747 (1954).

    CAS  Google Scholar 

  • Sheline, G. E., and D. E. Clark: Index of thyroid function: estimation by rate of organic binding of I131. J. Labor, a. Clin. Med. 36, 450 (1950).

    CAS  Google Scholar 

  • Sheline, G. E., M.C. Moore, A. Kappas and D.E. Clark: A correlation between the serum protein- bound iodine and the radioiodine conversion ratio in various thyroid states. J. Clin. Endocrin. 11, 91 (1951).

    CAS  Google Scholar 

  • Shipley, R. A., and R. E. Clark: Performance of a sodium iodide scintillation counter in measurement of I131 uptake by the thyroid. J. Labor, a. Clin. Med. 41, 179 (1953).

    CAS  Google Scholar 

  • Shipley, R. A., J. P. Storaasli, H. L. Friedell and A. M. Potts: I131 in the diagnosis and treatment of hyperthyroidism. Amer. J. Roentgenol. 64, 576 (1950).

    CAS  Google Scholar 

  • Silver, S., and M. H. Fieber: Blood levels of I131 after tracer doses in the diagnosis of hyper-thyroidism. Proc. Soc. Exper. Biol. a. Med. 75, 570 (1950).

    CAS  Google Scholar 

  • Silver, S., M. H. Fieber and S. B. Yohalem: Blood levels after tracer doses of radioactive iodine in the diagnosis of thyroid disorders. Amer. J. Med. 13, 725 (1952).

    PubMed  CAS  Google Scholar 

  • Silverman, S. H., and L. Wilkins: Radioiodine uptake in the study of different types of hypothyroidism in childhood. Pediatrics 12, 288 (1953).

    PubMed  CAS  Google Scholar 

  • Sinclair, W. K., and E. W. Emery: The half-life of iodine131 and the anomalous decay of exposed sodium iodide sources. Brit. J. Radiol. 23, 576 (1950).

    PubMed  CAS  Google Scholar 

  • Skanse, B. N.: [1] Radioactive iodine: its use in studying the urinary excretion of iodine by humans in various states of thyroid function. Acta med. scand. (Stockh.) 131, 251 (1948).

    CAS  Google Scholar 

  • Skanse, B. N.: [2] The biologic effect of irradiation by radioactive iodine. J. Clin. Endocrin. 8, 707 (1948).

    CAS  Google Scholar 

  • Skanse, B. N.: [3] Radioactive iodine in the diagnosis of thyroid disease. Acta med. scand. (Stockh.) Suppl. 235 (1949).

    Google Scholar 

  • Skanse, B. N.: [4] The use of thyrotrophin in the differential diagnosis of primary and secondary hypo-thyroidism. Acta endocrinol. (Copenh.) 13, 358 (1953).

    CAS  Google Scholar 

  • Skanse, B. N. and D. S. Riggs: Thyrotoxicosis factitia (alimentary thyrotoxicosis). Its differentiation from spontaneous thyrotoxicosis with the aid of radioactive iodine. J. Clin. Endocrin. 8, 532 (1948).

    CAS  Google Scholar 

  • Smith, H. W.: Lectures on the Kidney. Lawrence, Kans.: Univ. Kansas 1943.

    Google Scholar 

  • Solomon, A. K.: Equations for tracer experiments. J. Clin. Invest. 28, 1297 (1949).

    PubMed  CAS  Google Scholar 

  • Spector, H., H. H. Mitchell and T. S. Hamilton: The effect of environmental temperature and of potassium iodide supplementation on the excretion of iodide by normal human subjects. J. of Biol. Chem. 161, 137 (1945).

    CAS  Google Scholar 

  • Speert, H., E. H. Quimby and S. C. Werner: Radioiodine uptake by the fetal mouse thyroid and resultant effects in later life. Surg. etc. 93, 230 (1951).

    CAS  Google Scholar 

  • Stanbury, J. B.: [1]Cretinism with goiter: a case report. J. Clin. Endocrin. 11, 740 (1951).

    CAS  Google Scholar 

  • Stanbury, J. B.: [2] Preliminary studies of iodine metabolism in patients from an area of endemic goitre. Bull. org. mond. Santé. 9, 183 (1953).

    CAS  Google Scholar 

  • Stanbury, J. B., G. L. Brownell, D. S. Riggs, H. Perinetti, E. Del Castillo and J. Itoiz: The iodine deficient human thyroid gland. A preliminary report. J. Clin. Endocrin. 12, 191 (1952).

    CAS  Google Scholar 

  • Stanbury, J. B., G. L. Brownell, D. S. Riggs, H. Perinetti, J. Itoiz and E. B. Del Castillo: Endemic Goiter: the Adaptation of Man to Iodine Deficiency. Cambridge, Mass.: Harvard Univ. Press 1954.

    Google Scholar 

  • Stanbury, J. B. and A. N. Hedge: A study of a family of goitrous cretins. J. Clin. Endocrin. 10, 1471 (1950).

    CAS  Google Scholar 

  • Stanbury, J. B., K. Ohela and R. Pitt-Rivers: Metabolism of iodine in 2 goitrous cretins compared with that in 2 patients receiving methimazole. J. Clin. Endocrin. 15, 54 (1955).

    CAS  Google Scholar 

  • Stanbury, J. B. and J. B. Wyngaarden: Effect of perchlorate on the human thyroid gland. Metabolism 1, 533 (1952).

    PubMed  CAS  Google Scholar 

  • Stanley, M. M.: The direct estimation of the rate of thyroid hormone formation in man. The effect of the iodide ion on thyroid iodine utilization. J. Clin. Endocrin. 9, 941 (1949).

    CAS  Google Scholar 

  • Stanley, M. M. and E. B. Astwood: [1] Determination of the relative activities of antithyroid compounds in man using radioactive iodine. Endocrinology (Springfield, Ill.) 41, 66 (1947).

    CAS  Google Scholar 

  • Stanley, M. M. and E. B. Astwood: [2] The accumulation of radioactive iodide by the thyroid gland in normal and thyrotoxic subjects and the effect of thiocyanate on its discharge. Endocrinology (Springfield, Ill.) 42, 107 (1948).

    CAS  Google Scholar 

  • Stanley, M. M. and E. B. Astwood: [3] The response of the thyroid gland in normal human subjects to the administration of thyrotropin, as shown by studies with I131. Endocrinology (Springfield, Ill.) 44, 49 (1949).

    CAS  Google Scholar 

  • Stanley, M. M. and E. B. Astwood: [4] l-Methyl-2-mercaptoimidazole: an antithyroid compound highly active in man. Endocrinology (Springfield, Ill.) 44, 588 (1949).

    CAS  Google Scholar 

  • Starr, P., and R. Liebhold-Schueck: [1] Effect of oral thyroxine and tri-iodo-thyronine on radioactive iodine uptake and serum protein bound iodine in normal human subjects. Proc. Soc. Exper. Biol. a. Med. 83, 52 (1953).

    CAS  Google Scholar 

  • Starr, P., and R. Liebhold-Schueck: [2] Theory of thyroid hormone action. Conclusions derived from differences in effect of sodium-l-thyroxine, sodium-d-thyroxine, triiodothyronine, and potassium iodide on uptake of radioactive iodine by thyroid gland of normal subjects. Ann. Int. Med. 82, 880 (1953).

    Google Scholar 

  • Starr, P., G. Snipes and R. Liebhold-Schueck: Biologic effects of triiodothyronine in human subjects. J. Clin. Endocrin. 15, 98 (1955).

    CAS  Google Scholar 

  • Steiner, H., u. O. Voelkel: Die Schilddrüse nach der Strumektomie. (Untersuchungen mit radioaktivem Jod.) Wien. Z. inn. Med. 35, 515 (1954).

    PubMed  CAS  Google Scholar 

  • Stenstrom, K. W., and J. F. Marvin: Urinary excretion of radioiodine in a case of severe hyperthyroidism. Proc. Soc. Exper. Biol. a. Med. 66, 47 (1947).

    CAS  Google Scholar 

  • Sterling, K., J. C. Lashof and E.B. Man: Disappearance from serum of I131-labeled 1-thyroxine and 1-triiodothyronine in euthyroid subjects. J. Clin. Invest. 33, 1031 (1954).

    PubMed  CAS  Google Scholar 

  • Stöa, K. F.: The excretion of radioactive iodine after oral administration of small doses. Acta endocrinol. (Copenh.) 12, 97 (1953).

    Google Scholar 

  • Stoll, R., et P. Blanquet: Sur l’activité des thyroides de l’embryon de poulet, étudiée à l’aide du radio-iode I131. Ann. d’Endocrin. 13, 569 (1952).

    CAS  Google Scholar 

  • Storaasli, J. P., S. Rosenberg and H. L. Friedell: Effect of food and water on thyroid uptake of radio-iodine (I131). Proc. Soc. Exper. Biol. a. Med. 83, 748 (1953).

    CAS  Google Scholar 

  • Strauss, E., A. Jakob u. J. Hiller: Die Untersuchung der Schilddrüsenfunktion mit Radiojod. Med. Klin. 1951, 1102.

    Google Scholar 

  • Stump, W.: Ergebnisse des Radiojodtestes (Jodid131) bei endemischer Struma. Verh. dtsch. Ges. inn. Med. 59, 323 (1953).

    Google Scholar 

  • Süe, P., et M. Tubiana: Examen topographique de la glande thyroide par mesure externe des rayonnements y émis par I131. C. r. Acad. Sci. (Paris) 232, 572 (1951).

    Google Scholar 

  • Tait, J. F., J. R. Cook and R. Worsnop: Physical measurements in routine clinical diagnosis with I131. Brit. J. Radiol. 24, 14 (1951).

    PubMed  CAS  Google Scholar 

  • Taurog, A., F. N. Briggs and I. L. Chaikoff: [1] I131-labeled 1-thyroxine. I. An unidentified excretion product in bile. J. of Biol. Chem. 191, 29 (1951).

    CAS  Google Scholar 

  • Taurog, A., F. N. Briggs and I. L. Chaikoff: [2] I131-labeled 1-thyroxine. II. Nature of the excretion product in bile. J. of Biol. Chem. 194, 655 (1952).

    CAS  Google Scholar 

  • Taurog, A., and I. L. Chaikoff: [1] The metabolic interrelations of thyroxine and diiodotyrosine as shown by a study of their specific activity-time relations in rats injected with radioactive iodine. J. of Biol. Chem. 169, 49 (1947).

    CAS  Google Scholar 

  • Taurog, A., and I. L. Chaikoff: [2] On the nature of plasma iodine. J. of Biol. Chem. 171, 439 (1947).

    CAS  Google Scholar 

  • Taurog, A., and I. L. Chaikoff: [3] The nature of the circulating thyroid hormone. J. of Biol. Chem. 170, 639 (1948).

    Google Scholar 

  • Taurog, A., I. L. Chaikoff and D. D. Feller: The mechanism of iodine concentration by the thyroid gland: its non-organic iodine-binding capacity in the normal and propylthiouracil-treated rat. J. of Biol. Chem. 171, 189 (1947).

    CAS  Google Scholar 

  • Taurog, A., I. L. Chaikoff, and A. L. Franklin: The structural specifity of sulfonilamid-like compounds as inhibitors of the in vitro conversion of inorganic iodide to thyroxine and diiodotyrosine by thyroid tissue. J. of Biol. Chem. 161, 537 (1945).

    CAS  Google Scholar 

  • Taurog, A., I. L. Chaikoff and W. Tong: [1] On the occurence of monoiodotyrosine in the thyroid gland. J. of Biol. Chem. 178, 997 (1949).

    CAS  Google Scholar 

  • Taurog, A., I. L. Chaikoff and W. Tong: [2] The nature of plasma iodine as revealed by filter paper partition chromatography. J. of Biol. Chem. 184, 99 (1950).

    CAS  Google Scholar 

  • Taurog, A., I. L. Chaikoff, W. Tong and I. L. Chaikoff: [1] Fractionation of thyroid iodine by means of filter paper partition chromatography. Nature (London) 164, 181 (1949).

    CAS  Google Scholar 

  • Taurog, A., I. L. Chaikoff, W. Tong and I. L. Chaikoff: [2] The monoiodotyrosine content of the thyroid gland. J. of Biol. Chem. 184, 83 (1950).

    CAS  Google Scholar 

  • Taylor, S.: [1] The size of follicles in non-toxic goitre. Lancet 1952 I, 175.

    Google Scholar 

  • Taylor, S.: [2] The evolution of nodular goiter. J. Clin. Endocrin. 13, 1232 (1953).

    CAS  Google Scholar 

  • Taylor, S.: [3] An autoradiographic study of simple goitre. Bull. org. mond. Santé 9, 197 (1953).

    CAS  Google Scholar 

  • Taylor, S.: [4] Calcium as a goitrogen. J. Clin. Endocrin. 14, 1412 (1954).

    CAS  Google Scholar 

  • Taylor, S. and F. S. Stewart: Distribution of radioiodine in human thyroid glands. Lancet 1951 II, 232.

    Google Scholar 

  • Thibault, O.: Principales donées expérimentales concernant le rôle de la tri-iodothyronine en tant qu “hormone thyroidienne”. Ann. d’Endocrin. 14, 732 (1953).

    CAS  Google Scholar 

  • Thode, H. G., C. H. Jaimet and S. Kirkwood: Studies and diagnostic tests of salivary-gland and thyroid-gland function with radioiodine. New. Engl. J. Med. 251, 129 (1954),

    Google Scholar 

  • Thompson, W. O., L. L. Mclellan, P. K. Thompson and L. F. N. Dickie: The rates of utilization of thyroxine and of desiccated thyroid in man: the relation between the iodine in desiccated thyroid and in thyroxine. J. Clin. Invest. 12, 235 (1933).

    PubMed  CAS  Google Scholar 

  • Timmons, J. R., and J. M. Timmons: Lingual thyroid; the use of radioactive iodine in diagnosis. Ann. Surg. 133, 90 (1951).

    PubMed  CAS  Google Scholar 

  • Tishkoff, G. H., R. Bennett, V. Bennett and L. L. Miller: Radioiodine and paper chromatography technique in the study of thvroid metabolism. Science (Lancaster, Pa.) 110, 452 (1949).

    CAS  Google Scholar 

  • Tomich, E. G., and E. A. Woollett: The biological activity of triiodothyronine. Lancet 1953 I, 726.

    Google Scholar 

  • Tong, W., A. Taurog and I. L. Chaikoff: Nature of plasma iodine following destruction of the rat thyroid with I131. J. of Biol. Chem. 195, 407 (1952).

    CAS  Google Scholar 

  • Trunnell, J. B., and F. T. Brayer: Factors governing the development of the chick embryo thyroid. I. Determination of the time at which I131 collection begins. J. Clin. Endocrin. 13, 88 (1953).

    CAS  Google Scholar 

  • Trunnell, J. B., L. D. Marinelli, B. J. Duffy, Jr., R. Hill, W. Peacock and R. W. Rawson: The treatment of metastatic thyroid cancer with radioactive iodine: credits and debits. J. Clin. Endocrin. 9, 1138 (1949).

    CAS  Google Scholar 

  • Trunnell, J. B., R. W. Rawson, L. D. Marinelli and R. Hill: The effect of thyroid stimulating hormone on the function of human normal and malignant thyroid tissue. J. Clin. Endocrin. 8, 598 (1948).

    CAS  Google Scholar 

  • Trunnell, J. B. and P. Wade: Factors governing the development of the chick embryo thyroid. II. Chronology of the synthesis of iodinated compounds studied by chromatographic analysis. J. Clin. Endocrin. 15, 107 (1955).

    CAS  Google Scholar 

  • Tubiana, M.: Mesure du temps de renouvellement d’hormone thyroidienne naturelle marquée par le radioiode chez le lapin et chez l’homme. C. r. Soc. Biol. (Paris) 145, 1011 (1951).

    CAS  Google Scholar 

  • Tubiana, M. et P. Stïe: Intérêt médical de l’examen topographique de la thyroide par mesure externe du radioiode. Presse méd. 1951, 1027.

    Google Scholar 

  • Vanderlaan, J. E., and W. P. Vanderlaan: The iodide concentrating mechanism of the rat thyroid, and its inhibition by thiocyanate. Endocrinology (Springfield, Ill.) 40, 403 (1947).

    CAS  Google Scholar 

  • Vanderlaan, W. P., and A. Bissell: Effects of propylthiouracil and potassium thiocyanate on the uptake of iodine by the thyroid gland of the rat. Endocrinology (Springfield, Ill.) 39, 157 (1946).

    CAS  Google Scholar 

  • Vanderlaan, W. P. and R. Caplan: Observations on a relationship between total thyroid iodine content and the iodide-concentrating mechanism of the thvroid gland of the rat. Endocrinology (Springfield, Ill.) 54, 437 (1954).

    CAS  Google Scholar 

  • Vanderlaan, W. P. and M. A. Greer: Some effects of the hypophysis on iodine metabolism by the thyroid gland of the rat. Endocrinology (Springfield, Ill.) 47, 36 (1950).

    CAS  Google Scholar 

  • Vannotti, A.: [1] Sur quelques discordances entre le métabolisme basal et le test au radio-iode dans l’étude de la fonction thyroidienne. Ann. d’Endocrin. 14, 455 (1953).

    CAS  Google Scholar 

  • Vannotti, A.: [2] Über die Anwendung des radioaktiven Jodes zur Prüfung der neuro-hormonalen Regulation der Schilddrüse. Strahlenther. Sonderb. 33, 96 (1955).

    Google Scholar 

  • Veall, N.: A Geiger-Müller counter for measuring the beta-ray activity of liquids, and its application to medical tracer experiments. Brit. J. Radiol. 21, 347 (1948).

    PubMed  CAS  Google Scholar 

  • Veall, N. and A. M. Baptista: A multi-tube gamma counting apparatus for small samples. Brit. J. Radiol. 27, 198 (1954).

    PubMed  CAS  Google Scholar 

  • Veall, N. and H. Vetter: An apparatus for the rapid estimation of tracer quantities of radioactive isotopes in excreta. Brit. J. Radiol. 25, 85 (1952).

    PubMed  CAS  Google Scholar 

  • Veil, W. H., u. A. Stitrm: Beiträge zur Kenntnis des Jodstoffwechsels. Dtsch. Arch. klin. Med. 14, 166 (1925).

    Google Scholar 

  • Vetter, H.: [1] Zur Methodik der Radiojodbestimmung im Harn. Wien. Z. inn. Med. 32, 436 (1951).

    CAS  Google Scholar 

  • Vetter, H.: [2] Einige graphische Behelfe zur Ermittlung einer therapeutisch wirksamen Radio jodmenge. Strahlenther. 93, 118 (1954).

    CAS  Google Scholar 

  • Vetter, H.: [3] Diskussionsbemerkungen zu ROTBLAT und OWEN, A. E. R. E. Radioisotope Conference 1954. Vol. I. S. 74. London: Butterworths 1954.

    Google Scholar 

  • Vickery, A. L.: Histologie effects of therapeutic doses of radioactive iodine on the thyroid gland of man. Amer. J. Path. 28, 552 (1952).

    Google Scholar 

  • Visscher, M. De, et J. Lederer: Emploi de l’hormone thyréotrope dans le diagnostic des hypothyroidies. Ann. d’Endocrin. 15, 622 (1954).

    Google Scholar 

  • Visscher, M. De, G. B. Mcadams et W. T. Salter: Emploi de l’iode radioactif dans la détermination de l’activité sécrétoire thyroidienne. Ann. d’Endocrin. 12, 573 (1951).

    Google Scholar 

  • Visscher, M. De et J. De Schrevel: Fonctions thyroidiennes et radioactivité du sang après administration de radioiode. Ann. d’Endocrin. 14, 460 (1953).

    Google Scholar 

  • Vogliazzo, u., G. Viale, A. Scorta E E. Marchis: Valutazione de la funzione tiroidea nel cretinismo endemico. Rass. clin. Sci. 28, 53 (1952).

    Google Scholar 

  • Wallace, G. B., and B. B. Brodie: The distribution of administered iodide and thiocyanate in comparison with chloride, and their relation to body fluids. J. Pharmacol, a. Exper. Ther. 61, 397 (1937).

    CAS  Google Scholar 

  • Warren, S.: Effects of radiation on normal tissues. Arch, of Path. 35, 304 (1943).

    Google Scholar 

  • Wayne, E. J.: The diagnosis of thyrotoxicsis. Brit. Med. J. 1954 I, 411.

    Google Scholar 

  • Werner, S. C., L. D. Goodwin and E. H. Qtjimby: The tracer technique with radioactive iodine, I131, as a potential substitute for the basal metabolic rate determination in routine clinical practice. J. Clin. Endocrin. 9, 664 (1949).

    Google Scholar 

  • Werner, S. C. and H.B. Hamilton: Hyperthyroidism without apparent hypermetabolism. J. Amer. Med. Assoc. 146, 450 (1951).

    CAS  Google Scholar 

  • Werner, S. C., H.B. Hamilton, E. Leifer and L. D. Goodwin: An appraisal of the radioiodine tracer technic as a clinical procedure in the diagnosis of thyroid disorders. J. Clin. Endocrin. 10, 1054 (1950).

    CAS  Google Scholar 

  • Werner, S. C., H.B. Hamilton and M. R. Nemeth: [1] Therapeutic effects in hyperthyroidism from repeated diagnostic doses of I131. Radiology 59, 720 (1952).

    PubMed  CAS  Google Scholar 

  • Werner, S. C., H.B. Hamilton and M. R. Nemeth: [2] Therapeutic effects from repeated diagnostic doses of I131 in adult and juvenile hyperthyroidism. J. Clin. Endocrin. 12, 1349 (1952).

    CAS  Google Scholar 

  • Werner, S. C. and E. H. Quimby: The use of radioactive iodine in the study of normal and disordered thyroid function in man. J. Clin. Endocrin. 8, 597 (1948).

    CAS  Google Scholar 

  • Werner, S. C.,E. H. Quimby and C. Schmidt: [1] Radioactive I131 in the treatment of toxic goiter and as indicator of thyroid function in man. Brookhaven Conference Report on Radio-Iodine, S. 69, 1948.

    Google Scholar 

  • Werner, S. C., E. H. Quimby and C. Schmidt: [2] The use of tracer doses of radioactive iodine, I131, in the study of normal and disordered thyroid function in man. J. Clin. Endocrin. 9, 342 (1949).

    CAS  Google Scholar 

  • Wespi, H. J.: Jodprophylaxe und Jodmangel theorie. Untersuchungen über die Schilddrüsen - Verhältnisse bei Schulkindern in einigen Schweizer Dörfern. Schweiz, med. Wschr. 1953, 452.

    Google Scholar 

  • White, W. E.: The rate of formation of nondiffusible (organic) fraction of I131 in plasma correlated with apparent thyroid state. J. Labor, a. Clin. Med. 41, 516 (1953).

    CAS  Google Scholar 

  • White, W. E. and W. A. Reilly: Chromatographic changes in plasma I131 during the treatment of Graves’ and cardiac disease correlated with clinical course. J. Labor, a. Clin. Med. 43, 553 (1954).

    CAS  Google Scholar 

  • Wilkins, L., G. W. Clayton and M. Berthrong: Development of goiters in cretins without iodine deficiency: hypothyroidism due to apparent inability of the thyroid gland to synthesize hormone. Pediatrics 13, 235 (1954).

    PubMed  CAS  Google Scholar 

  • Williams, R. H., H. Jaffe and B. Bernstein: Comparison of the distribution of radioactive iodine in serum and urine in different levels of thyroid function. J. Clin. Invest. 28, 1222 (1949).

    CAS  Google Scholar 

  • Winzler, R. J., and S. R. Notrica: Association of thyroxine with plasma proteins. Federat. Proc. 11, 312 (1952).

    Google Scholar 

  • Wolff, J.: Some factors that influence the release of iodine from the thyroid gland. Endocrinology (Springfield, Ill.) 48, 284 (1951).

    CAS  Google Scholar 

  • Wolff, J. and I. L. Chaikoff: [1] The inhibitory action of iodide upon organic binding of iodine by the normal thyroid gland. J. of Biol. Chem. 172, 855 (1948).

    CAS  Google Scholar 

  • Wolff, J. and I. L. Chaikoff: [2] Plasma inorganic iodine, a chemical regulator of normal thyroid function. Endocrinology (Springfield, Ill.) 42, 468 (1948).

    CAS  Google Scholar 

  • Wolff, J. and I. L. Chaikoff: [3] The inhibitory action of excessive iodide upon the synthesis of diiodotyrosine and of thyroxine in the thyroid gland of the normal rat. Endocrinology (Springfield, Ill.) 43, 174 (1948).

    CAS  Google Scholar 

  • Wolff, J. and I. L. Chaikoff: [4] Plasma inorganic iodide as a homeostatic regulator of thyroid function. J. of Biol. Chem. 174, 555 (1948).

    CAS  Google Scholar 

  • Wolff, J., I. L. Chaikoff, R. C. Goldberg and J. R. Meier: The temporary nature of the inhibitory action of excess iodide on organic iodine synthesis in the normal thyroid. Endocrinology (Springfield 111.) 45, 504 (1949).

    CAS  Google Scholar 

  • Wolff, J., I. L. Chaikoff, A. Tattrog and L. Rubin: The disturbance in iodine metabolism produced by thiocyanate: the mechanism of its goitrogenic action with radioactive iodine as indicator. Endocrinology (Springfield, Ill.) 39, 140 (1946).

    CAS  Google Scholar 

  • Wollman, S. H.: A thyroid model describing kinetics of exchange, concentrating, and organic binding of iodide. Endocrinology (Springfield, Ill.) 54, 35 (1954).

    CAS  Google Scholar 

  • Wollman, S. H. and R. D. Scow: [1] The effect of propylthiouracil on radioiodide concentrating by the thyroid gland in normal and hypophysectomized mice. Endocrinology (Springfield, Ill.) 53, 332 (1953).

    CAS  Google Scholar 

  • Wollman, S. H. and R. D. Scow: [2] Dependence of ratio of radioiodide concentrations in thyroid gland and serum on serum iodide concentration: with propylthiouracil. Endocrinology (Springfield, Ill.) 55, 828 (1954).

    CAS  Google Scholar 

  • Wollman, S. H. and R. D. Scow: [3] Dependence of ratio of radioiodide concentrations in thyroid gland and serum on serum iodide concentration: without propylthiouracil. Endocrinology (Springfield, Ill.) 55, 837 (1954).

    CAS  Google Scholar 

  • Wyngaarden, J. B., J. B. Stanbttry and B. Rapp: The effects of iodide, Perchlorate, thiocyanate, and nitrate administration upon the iodide concentrating mechanism of the rat thyroid. Endocrinology (Springfield, Ill.) 52, 568 (1953).

    CAS  Google Scholar 

  • Wyngaarden, J. B., B. M. Wright and P. Ways: The effect of certain anions upon the accumulating and retention of iodide by the thyroid gland. Endocrinology (Springfield, Iu.) 50, 537 (1952).

    CAS  Google Scholar 

  • Yount, E., and J. M. Little: Renal clearance in patients with myxedema. J. Clin. Endocrin. 15, 343 (1955). Zakovsky, J.: Persönliche Mitteilung.

    Google Scholar 

  • Zilversmit, D. B., C. Entenman and M. C. Fishler: On the calculation of “turnover time” and “turnover rate” from experiments involving the use of labeling agents. J. Gen. Physiol. 26, 325 (1943).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1955 Springer-Verlag OHG. Berlin · Göttingen · Heidelberg

About this paper

Cite this paper

Vetter, H. (1955). Die Diagnostik der Schilddrüsen-Erkrankungen mit radioaktivem Jod. In: Heilmeyer, L., Schittenhelm, A., Schoen, R., Glanzmann, E., de Rudder, B. (eds) Ergebnisse der Inneren Medizin und Kinderheilkunde. Ergebnisse der Inneren Medizin und Kinderheilkunde, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-94644-8_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-94644-8_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-94645-5

  • Online ISBN: 978-3-642-94644-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics