Skip to main content
SpringerLink
Log in

β-Blocker bei schwerer Herzinsuffzienz

  • Chapter
Der schwerkranke und multimorbide Herzpatient

  • 47 Accesses

Zusammenfassung

Die 1987 publizierte CONSENSUS-I-Studie zeigte erstmals, dass mit der Gabe von ACE-Hemmern, hier Enalapril, die Mortalität von Patienten mit schwerer Herzinsuffizienz (NYHA IV) reduziert werden kann [3]. Obwohl der 10-Jahres-Followup der Patienten der CONSENSUS-I-Studie auch unter kontinuierlicher Therapie mit ACE-Hemmern eine weiterhin unbefriedigend hohe Mortalität zeigte [9], wurde mit dieser Studie doch erstmals die neurohumorale Hypothese bei der Herzinsuffizienz klinisch eindrücklich bestätigt.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Bristow MR (2000) β-adrenergic receptor blockade in chronic heart failure. Circulation 101: 558–569

    PubMed  CAS  Google Scholar 

  2. CIBIS-II Investigators and Committees (1999) The cardiac insufficiency bisoprolol study II (CIBIS-II): a randomised trial. Lancet 353: 9–13

    Article  Google Scholar 

  3. The CONSENSUS Trial Study Group (1987) Effects of enalapril on mortality in severe heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 316: 1429–1435

    Article  Google Scholar 

  4. Kaye DM, Lefkovits J, Jennings GL et al. (1995) Adverse consequences of high sympathetic nerve activity in the failing human heart. J Am Coll Cardiol 26: 1257–1263

    Article  PubMed  CAS  Google Scholar 

  5. Kukin ML, Kalmann J, Mannino N, Freudenberger R, Buchholz C, Ocampo O (1996) Combined alpha-beta blockade (doxzosin plus metoprolol) compared with beta blockade alone in chronic congestive heart failure. Am J Cardiol 77: 486–491

    Article  PubMed  CAS  Google Scholar 

  6. Kurz T, Richardt D, Görge B et al. (2000) Differential effects of carvedilol on norepinephrine release in normoxic and ischemic heart. J Cardiovasc Pharmacol 36: 96–100

    Article  PubMed  CAS  Google Scholar 

  7. MERIT-HF Study Group (1999) Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL randomized intervention trial in congestive heart failure (MERIT-HF). Lancet 353: 2001–2006

    Article  Google Scholar 

  8. Packer M, Coats AJS, Fowler MB et al. (2001) Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 344: 1651–1658

    Article  PubMed  CAS  Google Scholar 

  9. Swedberg K, Kjekshus J, Snapinn S for the CONSENSUS investigators (1999) Long-term survival in severe heart failure in patients treated with enalapril. Ten year follow-up of CONSENSUS I. Eur Heart J 20: 136–139

    Article  PubMed  CAS  Google Scholar 

  10. Ungerer M, Hartmann F, Richardt G (1996) Das sympatho-adrenerge System bei Herzinsuffizienz. Dtsch Med Wochenschr 121: 141–145

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medizinische Klinik II, Universitätsklinikum Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland

    Prof. Dr. G. Richardt

  2. Medizinische Klinik II, Universitätsklinikum Lübeck, Deutschland

    T. Kurz, F. Hartmann & H. A. Katus

Authors
  1. Prof. Dr. G. Richardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. Kurz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. Hartmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. A. Katus
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Herz-Kreislauf-Klinik Waldkirch, Kandelstraße 41, 79183, Waldkirch, Deutschland

    Bernhard Rauch

  2. Deutsche Gesellschaft für Prävention und Rehabilitation von Herz-Kreislauf-Erkrankungen, Friedrich-Ebert-Ring 38, 56058, Koblenz, Deutschland

    Klaus Held

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Steinkopff Verlag Darmstadt

About this chapter

Cite this chapter

Richardt, G., Kurz, T., Hartmann, F., Katus, H.A. (2001). β-Blocker bei schwerer Herzinsuffzienz. In: Rauch, B., Held, K. (eds) Der schwerkranke und multimorbide Herzpatient. Steinkopff. https://doi.org/10.1007/978-3-642-93723-1_22

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-93723-1_22

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-1323-5

  • Online ISBN: 978-3-642-93723-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation