Untersuchungsstrategien der Leber — Parameteroptimierung

  • E. Rummeny
  • P. E. Peters
Conference paper

Zusammenfassung

Die Magnetresonanztomographie (MRT) gewinnt aufgrund ihres hohen Weiehteilkontrastes und durch die Einführung verbesserter Techniken zunehmend an Bedeutung im Bereich der abdominellen Bildgebung. Besonders bewährt hat sich dieses Verfahren inzwischen bei der Erkennung und Differenzierung von fokalen Leberläsionen. Im Vergleich zu anderen radiologischen Verfahren ist die Bildqualität jedoch von einer deutlich größeren Anzahl einzelner Faktoren abhängig. Diese lassen sich unterteilen in gerätespezifische (Hardware) Komponenten (Feldstärke, Homogenität des Magnetfeldes, Qualität der Gradienten- und RF-Spulen u. a.) und Faktoren, die vom Bediener frei einstellbar sind (Art der Pulssequenz, Repetitionszeit, Echozeit, Anzahl der Bildmittelungen, Technik der Artefaktunterdrückung). Daher ist es von entscheidender Bedeutung möglichst optimale Parameter zur Detektion und Differenzierung von Leberläsionen zu definieren um die diagnostische Aussagekraft der MR-Bilder zu optimieren [11, 14, 29].

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Literatur

  1. 1.
    Bailes DR, Gilderdale DJ, Bydder GM, Collins AG, Firmin DN (1985) Respiratory ordered phase encoding (ROPE): a method for reducing respiratory motion artifacts in MR imaging. J Comput Assist Tomogr 9: 835–838PubMedCrossRefGoogle Scholar
  2. 2.
    Bousquet JC, Saini S, Stark DD, Hahn PF, Nigam M, Wittenberg J, Ferrucci JT (1988) Gadolinium-DOTA: characterization of a new paramagnetic complex. Radiology 166: 693–698PubMedGoogle Scholar
  3. 3.
    Buxton RB, Edelman RR, Rosen BR, Wismer GL, Brady TJ (1987) Contrast in rapid MR imaging: T1- und T2-weighted imaging. J Comput Assist Tomogr 11 (1): 7–16PubMedCrossRefGoogle Scholar
  4. 4.
    Buxton RB, Fisel CR, Chien D, Brady TJ (1989) Signal intensity in fast NMR Imaging with short repetition times. J of Magn Reson, 83: 576–585CrossRefGoogle Scholar
  5. 5.
    Dousset M, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Elizondo G, Hahn PF, Saini S, Ferrucci JT (1989) Short T1 inversion-recovery imaging of the liver: pulse- sequence optimization and comparsion with spin-echo imaging. Radiology 171: 327–333PubMedGoogle Scholar
  6. 6.
    Edelman RR, Hahn PF, Buxton R, Wittenberg J, Ferrucci JT, Saini S, Brady TJ (1986) Rapid MR imaging with suspended respiration: Clinical application in the liver. Radiology 161: 125–131PubMedGoogle Scholar
  7. 7.
    Edelman RR, Atkinson DJ, Silver MS, Loaiza FL, Warren WS (1988) FRODO pulse sequences: A new means of eliminating motion, flow and wraparound artifacts. Radiology 166: 231–236PubMedGoogle Scholar
  8. 8.
    Foley WD, Kneeland JB, Cates JD, Kellman GM, Lawson TL, Middleton WD, Hendrick RE (1987) Contrast optimization for the detection of focal hepatic lesions by MR imaging at 1.5 T. AJR 149: 1155–1160PubMedGoogle Scholar
  9. 9.
    Fretz CJ, Elizondo G, Weissleder R, Hahn PF, Stark DD, Ferrucci JT Jr. (1989) Superparamagnetic iron oxide-enhanced MR imaging: Pulse sequence optimization for detection of liver cancer. Radiology 172: 393–397PubMedGoogle Scholar
  10. 10.
    Hamm B, Felix R, Wolf KJ (1989) Dynamische MR-Tomographie intrahepatischer Tumoren. Fortsch Röntgenstr 150, 4: 434–441CrossRefGoogle Scholar
  11. 11.
    Hendrick RE, Nelson TR, Hendee WR (1984) Optimizing tissue contrast in magnetic resonance imaging. Magn Reson Imag, Vol. 2, pp. 192–204Google Scholar
  12. 12.
    Henkelman RM, Hardy P, Poon PY, Bronskill MJ (1986) Optimal pulse sequence for imaging hepatic metastases. Radiology 161: 727–734PubMedGoogle Scholar
  13. 13.
    Itho K, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Ferrucci JT(1989) MR imaging contrast parameters: correlation with lesion detectability. Radiology 173 (P):228Google Scholar
  14. 14.
    Kneeland JB, Knowles JR, Cahill DT (1984) Magnetic resonance imaging systems: Optimization in clinical use. Radiology 153: 473–478PubMedGoogle Scholar
  15. 15.
    Reinig JW, Dwyer AJ, Miller DL, White M, Frank JA, Sugarbaker PH, Chang AE, Doppmann JL (1987) Liver metastases detection: Comparative sensitivities of MR imaging and CT. Radiology 162: 43–47PubMedGoogle Scholar
  16. 16.
    Ruda H, Weissleder R (1988) Persönliche Mitteilung, BostonGoogle Scholar
  17. 17.
    Rummeny E, Saini S, Stark DD, Weissleder R, Compton CC, Ferrucci JT (1989) Detection to hepatic metastases with MR imaging: Spin-Echo vs phase-contrast pulse sequences at 0.6 T. AJR, 153: 1207–1211PubMedGoogle Scholar
  18. 18.
    Rummeny E, Stark DD, Weissleder R, Saini S, Hahn PF, Simeone JF, Gelker SC, Wittenberg J, Ferrucci JT (1987) Differential diagnosis of hepatic hemangioma and metastases by MR imaging: quantitative and qualitative criteria. Radiology 165 (P): 147Google Scholar
  19. 19.
    Rummeny E, Wernecke K, Vassallo P, Bongartz G, Östmann J, Kirelitz D, Wiesmann W, Reiser M, Peters PE(1989) High-field MR imaging versus CT in the detection of hepatic metastases: prospektion study. Radiology 173 (P):174Google Scholar
  20. 20.
    Runge VM, Wood ML (1988) Fast imaging and other motion artifact reduction schemes: a pictorial overview. Magn Reson Imag, pp 595–608Google Scholar
  21. 21.
    Saini S, Stark DD, Wittenberg J, Brady TH, Ferrucci JT (1986) Dynamic gadolinium- DTPA imaging of liver cancer: animal investigation. AJR 147: 357–362PubMedGoogle Scholar
  22. 22.
    Saini S, Stark DD, Hahn PF, Wittenberg J, Brady TJ, Ferrucci JT (1987) Ferrite particles: a superparamagnetic MR contrast agent for enhanced detection of liver cancer. Radiology 162: 217–222PubMedGoogle Scholar
  23. 23.
    Stark DD, Wittenberg J, Edelmann RR, Middelton MS, Saini S, Butch RY, Brady TJ, Ferrucci JT (1986) Detection of hepatic metastases: analysis of pulse sequence performance in MR imaging. Radiology 159: 365–370PubMedGoogle Scholar
  24. 24.
    Stark DD, Hendrick RE, Hahn PF, Ferrucci JT Jr. (1987) Motion artifact reduction with fast spin-echo imaging. Radiology 164: 183–191PubMedGoogle Scholar
  25. 25.
    Stark DD, Wittenberg J, Butch RJ, Ferrucci JT Jr (1987) Hepatic metastases: Randomized controlled comparsion of detection with MR-imaging and CT. Radiology, 165: 399–406PubMedGoogle Scholar
  26. 26.
    Stark DD, Weissleder R, Elizondo G, Hahn PF, Saini S, Todd LE, Wittenberg J, Ferrucci JT (1988) Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver. Radiology 168: 297–301PubMedGoogle Scholar
  27. 27.
    teStrake LT, Freiing NJM, Kamman RL, Mooyaart EL, Doorenbos H, Schraffordt Koops H (1989) Abdominal applications of fast MR imaging: A comparison of fast field echo (FFE) and spin echo ( SE) pulse sequences. Magn Reson Imag, 297–303Google Scholar
  28. 28.
    Tsang YM, Stark DD, Chen MC, Weissleder R, Wittenberg J, Ferrucci JT (1988) Hepatic micrometastases in the rat with ferrite enhanced MR imaging. Radiology 167: 21–24PubMedGoogle Scholar
  29. 29.
    Wehrli FW, MacFall DJR, Glover GH, Grigsby N, Haughton V, Johanson J (1984) The dependence of nuclear magnetic resonance ( NMR) image contrast on intrinsic and pulse sequence timing parameters. Magn Reson Imag 2: 3–16CrossRefGoogle Scholar
  30. 30.
    Weissleder R, Stark DD (1989) Magnetic resonance imaging of the liver. Magn Reson Quarter 5: 97–121Google Scholar
  31. 31.
    Wittenberg J, Stark DD, Forman B, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT(1988) Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR 151: 79–84PubMedGoogle Scholar
  32. 32.
    Wood ML, Runge VM, Henkelman RM (1988) Overcoming motion in abdominal MR imaging. AJR 150: 513–522PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • E. Rummeny
  • P. E. Peters

There are no affiliations available

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