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The Synthon Model and Organic Synthesis

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Synthon Model of Organic Chemistry and Synthesis Design

Part of the book series: Lecture Notes in Chemistry ((LNC,volume 51))

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Abstract

Chemical synthesis is one of the most important tasks both of pure as well as of applied organic chemistry. Since the middle of the 1960s, attempts have been made to explore the initial stages of organic synthesis design (e.g. searching for the most effective synthetic steps to prepare the target compound from the available substrate and reagents) using computers. This so-called computer-assisted organic synthesis formed a new branch of theoretical (or rather computational) chemistry. There are three basic approaches of interest in this field: (i) Synthesis in the forward direction, (ii) retrosynthesis, and (iii) reaction mechanisms of particular reactions. The third of these items has already been discussed in Chap. 4.

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Authors and Affiliations

  1. Department of Organic Chemistry, J.E. Purkyně University, CSSR-611 37, Brno, Czechoslovakia

    J. Koča

  2. Research Institute of Pure Chemicals, Lachema, CSSR-621 33, Brno, Czechoslovakia

    M. Kratochvíl & L. Matyska

  3. Department of Mathematics, Slovak Technical University, CSSR-812 37, Bratislava, Czechoslovakia

    V. Kvasnička & J. Pospíchal

Authors
  1. J. Koča
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  2. M. Kratochvíl
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  3. L. Matyska
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  4. V. Kvasnička
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  5. J. Pospíchal
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© 1989 Springer-Verlag Berlin Heidelberg

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Koča, J., Kratochvíl, M., Matyska, L., Kvasnička, V., Pospíchal, J. (1989). The Synthon Model and Organic Synthesis. In: Synthon Model of Organic Chemistry and Synthesis Design. Lecture Notes in Chemistry, vol 51. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-93416-2_6

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  • DOI: https://doi.org/10.1007/978-3-642-93416-2_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50932-5

  • Online ISBN: 978-3-642-93416-2

  • eBook Packages: Springer Book Archive

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