Advertisement

The Applied Synthon Model

  • J. Koča
  • M. Kratochvíl
  • L. Matyska
  • V. Kvasnička
  • J. Pospíchal
Part of the Lecture Notes in Chemistry book series (LNC, volume 51)

Abstract

In the preceding chapter we have defined the notion of a synthon. Its main difference from the molecular graph (Chap. 2) is that some of its vertices are distinguished from others by virtue of being so-called virtual vertices. In our forthcoming considerations we shall often use the term atom instead of the mathematical term vertex. The virtual vertex, or atom, represents a “virtual” functional group or a molecular fragment irrelevant for the chemical transformations of interest. Let us consider a synthon constructed over an atomic set A, this synthon is chemically described by a structural formula in which some bonds are not terminated by atoms. Loosely speaking, they are sticking out of the structural formula and formally terminate in virtual atoms. A synthon constructed over the atomic set A will be denoted by the symbol S (A).

Keywords

Valence State Structural Formula Triple Bond Internal Component External Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References (Chapter 4)

  1. 1.
    Koča J (1989) J. Math. Chem. (in press)Google Scholar
  2. 2.
    Koča J (1989) Coll. Czech. Chem. Commun. (in press)Google Scholar
  3. 3.
    Dugundji J, Ugi I (1973) Top. Curr. Chem. 39:19Google Scholar
  4. 4.
    Pauling L (1931) J. Am. Chem. Soc. 53:1367CrossRefGoogle Scholar
  5. 5.
    Van Vleck JH (1934) J. Chem. Phys. 2:20CrossRefGoogle Scholar
  6. 6.
    Koča J, Kratochvíl M, Kunz M, Kvasniôka V (1984) Coll. Czech. Chem. Commun. 49:1247CrossRefGoogle Scholar
  7. 7.
    Kratochvíl M, Koča J (1985) Chemistry in graphs (in Czech), Lachema, BrnoGoogle Scholar
  8. 8.(a)
    Bock H, Bankmann H (1986) Angew. Chem. 98:287;CrossRefGoogle Scholar
  9. (8b).
    Sichl HH, Koch EW (1984) J. Org. Chem. 49:575;CrossRefGoogle Scholar
  10. (8c).
    Gisch JF, Landgrebe JA (1985) J. Org. Chem. 50:2050;CrossRefGoogle Scholar
  11. (8d).
    Redman EW (1984) J. Am. Chem. Soc. 106:4639;CrossRefGoogle Scholar
  12. (8e).
    Anderson DR, Bierbaum VM, DePuy ChH (1983) J. Am. Chem. Soc. 105:4244;CrossRefGoogle Scholar
  13. (8f).
    Weber L (1983) Angew. Chem. 95:539CrossRefGoogle Scholar
  14. 9.
    Kratochvíl M, Koča J, Kvasnička V (1985) Chem. Listy (in Czech) 79:807Google Scholar
  15. 10.
    Koča J, Kratochvíl M, Matyska L, Kvasnička V (1986) Coll. Czech. Chem. Commun. 51:2637CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • J. Koča
    • 1
  • M. Kratochvíl
    • 2
  • L. Matyska
    • 2
  • V. Kvasnička
    • 3
  • J. Pospíchal
    • 3
  1. 1.Department of Organic ChemistryJ.E. Purkyně UniversityBrnoCzechoslovakia
  2. 2.Research Institute of Pure Chemicals, LachemaBrnoCzechoslovakia
  3. 3.Department of MathematicsSlovak Technical UniversityBratislavaCzechoslovakia

Personalised recommendations