Gerinnung und Infektabwehr — Ein phylogenetisches Erfolgskonzept als Ursache disseminierter intravasaler Gerinnung?

  • A. Bierhaus
  • P. P. Nawroth
Conference paper


Die gleichzeitige Aktivierung der Immunantwort und des Gerinnungssystems nach Verletzung ist ein phylogenetisch altes, adaptives Prinzip, das bereits in frühen Entwicklungsstufen von Eukaryonten beobachtet werden kann. Die enge Verbindung von Gerinnung, Entzündung und Immunabwehr hat sich während der Evolution erhalten und kann im Menschen bei zahlreichen physiologischen Reaktionen auf potentiell schädigende Einflüsse nachgewiesen werden.


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  • A. Bierhaus
  • P. P. Nawroth

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