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AIDS und Interferone

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Interferone

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Zusammenfassung

1981 wurde das klinische Bild des sog. „erworbenen Immunmangelsyndroms“ („Aquired Immune Deficiency Syndrome“, AIDS) erstmals beschrieben [28]. Dieses Krankheitsbild ist charakterisiert durch einen komplexen erworbenen Immundefekt, der sich klinisch in der Entwicklung von opportunistischen Infektionen und Tumoren manifestiert [19]. Mittlerweile wurde das „Humane Immundefizienz Virus“ (HIV), ein Retrovirus aus der Gruppe der Lentiviren, als kausales Agens identifiziert [7, 67, 89] und gezeigt, daß das AIDS-Vollbild lediglich ein fortgeschrittenes Stadium eines breiten klinischen Spektrums der HIV-Infektion darstellt [9, 19]. 1988 waren über 3000 AIDS- Fälle in der Bundesrepublik gemeldet bei einer geschätzten Gesamtzahl von 50 000-100 000 HIV-infizierten Personen [81].

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  1. J. Lohmeyer
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Editors and Affiliations

  1. Med. Klinik III - Onkologie und Hämatologie, Städtisches Krankenhaus, Dhünnberg 60, D-5090, Leverkusen, Deutschland

    Norbert Niederle

  2. Abteilung Immunologie und Transfusionsmedizin, Medizinische Hochschule Hannover, Konstanty-Gutschow-Str. 8, D-3000, Hannover 61, Deutschland

    Peter von Wussow

  3. Zentrum für Innere Medizin und Dermatologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Str. 8, D-3000, Hannover 61, Deutschland

    Peter von Wussow

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Lohmeyer, J. (1990). AIDS und Interferone. In: Niederle, N., von Wussow, P. (eds) Interferone. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-93383-7_16

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