Congenital Rubella Syndrome (C.R.S.): Models of Disease Control by Vaccination

  • Roy M. Anderson
Conference paper
Part of the Lecture Notes in Biomathematics book series (LNBM, volume 57)


An important consequence of mass immunization programmes is their tendency to increase the average age at which an individual typically acquires an infection over that which pertained before vaccination. As emphasized in a number of recent papers, such an increase in the average age at infection may, under certain circumstances, result in an increased incidence of infection among older age classes of the community than was the case before the implementation of immunization (Knox, 1980; Dietz, 1981; Cvjetanovic, Grab and Dixon, 1982; Hethcote, 1983; Anderson and May, 1983a). This observation is a cause for concern if the effects of infection are typically more severe among adults than among children.


Vaccination Coverage Measle Vaccine Critical Coverage Congenital Rubella Syndrome Rubella Vaccination 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Roy M. Anderson
    • 1
  1. 1.Department of Pure and Applied Biology, Imperial CollegeLondon UniversityLondonUK

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