• Martin Eisen
Part of the Lecture Notes in Biomathematics book series (LNBM, volume 30)


This year, approximately 350,000 Americans will die from cancer. The number of new cases which develop yearly is twice this figure. Cancer strikes 7,000 children each year. The purpose of this monograph is to indicate how mathematicians can play an important role in irradicating this disease.


Tumor Regression Acute Leukemia Cancer Chemotherapy Burkitts Lymphoma Biochemical Difference 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Becker, F.F. (editor). Cancer, A Comprehensive Treatise, Vol. 5, Chemotherapy, Plenum Press, New York, 1977.Google Scholar
  2. 2.
    Burchenal, J.H. The historical development of cancer chemotherapy, Seminars in Oncol., 4, 135–146, 1977.Google Scholar
  3. 3.
    Busch, H. and Lane, M. Chemotherapy, Year Book Medical, Chicago, 1967.Google Scholar
  4. 4.
    Carbone, P.P. Systemic treatment of breast cancer: past, present, and future, Int. J. Radiat. Oncol. Biol. Phys., 1, 759–767, 1976.CrossRefGoogle Scholar
  5. 5.
    Clarkson, B. and Fried, J. Changing concepts of the treatment of acute leukemia, Med. Cli. N. Amer., 55, 561–600, 1971.Google Scholar
  6. 6.
    Enstrom, J.E. and Austin, D.F. Interpreting cancer survival rates, Science, 195, 847–851, 1977.CrossRefGoogle Scholar
  7. 7.
    Farber, S., Diamond, L.K., Mercer, R.D., Sylvester, R.F., and Wolfe, J.A. Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroylglutamic acid (aminopterin), New England J. Med., 238, 787–793, 1948.CrossRefGoogle Scholar
  8. 8.
    Krakoff, I.H. Cancer chemotherapeutic agents. Ca-A Cancer J. for Clinicians, 27, 130–143, 1977.CrossRefGoogle Scholar
  9. 9.
    Li, M.C., Hertz, R., Spencer, D.B. Effects of methotrexate therapy upon choriocarcinoma and chorioadenoma, Proc. Soc. Exp. Biol., New York, 93, 361–366, 1956.Google Scholar
  10. 10.
    McKerns, K.W. (editor). Hormones and Cancer, Academic Press, New York, 1974.Google Scholar
  11. 11.
    Pratt, W.B. Fundamentals of Chemotherapy, Oxford University Press, Oxford, 1973.Google Scholar
  12. 12.
    Sartorelli, A.C. (editor). Cancer Chemotherapy, Am. Chem. Soc, Washington (D.C.), 1976.Google Scholar
  13. 13.
    Sartorelli, A.C. and Johns, D.G. (editors). Antineoplastic and Immunosuppressive Agents, Part 1. Springer-Verlag, New York, 1974.Google Scholar
  14. 14.
    Segaloff, A. The treatment of human malignancies with steroids. In Methods of Hormone Research (Steroidal Activity in Experimental Animals and Man. Part C) Vol. 5, 203–213, edited by R.I. Dorfman, Academic Press, New York, 1966.Google Scholar
  15. 15.
    Skipper, H. Combination therapy: some concepts and results, Canc. Chemo. Reports, Pt. 2, Vol. 4, No. 1, 137–145, 1974.Google Scholar
  16. 16.
    Swan, G. Some Current Mathematical Topics in Cancer, Monograph Publishing, University Microfilms, Ann Arbor, 1978.Google Scholar
  17. 17.
    Weed, R. (editor). Hematology for Internists, Little, Brown and Co., Boston, 1971.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • Martin Eisen
    • 1
  1. 1.Department of MathematicsTemple UniversityPhiladelphiaUSA

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