A “Case-Control Analysis within a Cohort-Study” about Malignant Lymphomas among Rubber and Tire Industry Workers

Epidemiologic Studies of the Occupational Health Studies Group (OHSG) of the University of North Carolina at Chapel Hill
  • U. Keil
  • D. Andjelkovich
  • E. Hunt
  • M. Symons
  • H. A. Tyroler
Conference paper
Part of the Lecture Notes in Medical Informatics book series (LNMED, volume 5)

Abstract

“Epidemiological studies provide an effective tool for evaluating possible causal relationships between occupational exposure and health in employed populations. Their major usefulness is not so much in the study of obvious events such as occupational injuries but in the examination of illness and death which may occur after many years of exposure and possibly even after exposure has ended.” (5)

Keywords

Lymphoma Benzene Leukemia Toluene Hydrocarbon 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Andjelkovich, D.A., Arp, E.W., Easter, P.N., Ellis, L.E., Harrell, T.J., McMichael, A.J., Smith, A.H., Tyroler, H.A., Wolf, P.H.: An Epidemiologic Study of Leukemia Among Rubber and Tire Industry Workers. Occupational Health Studies Group, School of Public Health, University of North Carolina, Chapel Hill, N.C. A Report for the National Cancer Institute, September 1977.Google Scholar
  2. 2.
    Arp, E.W., Wolf, P.H., Hunt, E.: A Retrospective Assessment of Solvent Exposure and the Relationship to Lymphatic Leukemia. Presented at the Southeastern Occupational Health and Safety Conference, Hilton Head, S.C., November 9–11, 1978.Google Scholar
  3. 3.
    Cole, P.: The Ascendence of the Case-Control Study. Presented at the Symposium on Case-Control Studies, Bermuda, April 6–8, 1978.Google Scholar
  4. 4.
    Epidemiology 268 Lecture Notes: Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, N.C., Spring Semester, 1978.Google Scholar
  5. 5.
    Gaffey, W.R.: A Brief Overview of Occupational Epidemiology. Manufacturing Chemists Association, December 1976.Google Scholar
  6. 6.
    International Classification of Diseases, 8th Revision, Vol. 1. U.S. Department of Health, Education and Welfare, Public Health Service.Google Scholar
  7. 7.
    International Classification of Diseases, 9th Revision. World Health Organization, Geneva, 1978.Google Scholar
  8. 8.
    Kupper, L.L., McMichael, A.J., Spirtas, R.: A Hybrid Epidemiologic Study Design Useful in Estimating Relative Risk. Am. Statist. Assoc. 70 (351): 524–528, September 1975.CrossRefGoogle Scholar
  9. 9.
    Li, F.P., Fraumeni, J.F., Mantel, N., Miller, R.W.: Cancer Mortality Among Chemists. J. Natl. Cancer Inst. 43: 1150–1154, 1969.Google Scholar
  10. 10.
    MacMahon, B., Pugh, T.F.: Epidemiology, Principles and Methods. Little, Brown and Company, Boston, 1970.Google Scholar
  11. 11.
    McMichael, A.J., Spirtas, R., Kupper, L.L.: An Epidemiologic Study of Mortality Within a Cohort of Rubber Workers, 1964–1972. J. Occup. Med. 16 (7): 458–464, July 1974.PubMedGoogle Scholar
  12. 12.
    McMichael, A.J., Spirtas, R., Kupper, L.L., Gamble, J.F.: Solvent Exposure and Leukemia Among Rubber Workers: An Epidemiologic Study. J. Occup. Med. 17 (4): 234–239, April 1975.PubMedGoogle Scholar
  13. 13.
    McMichael, A.J., Spirtas, R., Gamble, J.F., Tousey, P.M.: Mortality Among Rubber Workers: Relationship to Specific Jobs. J. Occup. Med. 18 (3): 178–185, March 1976.PubMedCrossRefGoogle Scholar
  14. 14.
    McMichael, A.J.: Standardized Mortality Ratios and the “Healthy Worker Effect”: Scratching Beneath the Surface. J. Occup. Med. 18 (3): 165–168, March 1976.PubMedCrossRefGoogle Scholar
  15. 15.
    McMichael, A.J., Andjelkovich, D.A., Tyroler, H.A.: Cancer Mortality Among Rubber Workers: An Epidemiologic Study. Annals of the New York Academy of Sciences 271: 125–137, May 1976.PubMedCrossRefGoogle Scholar
  16. 16.
    Mantel, H., Haenszel, W.: Statistical Aspects of the Analysis of Data from Retrospective Studies of Disease. J. Natl. Cancer Inst. 22: 719–748, 1959.PubMedGoogle Scholar
  17. 17.
    Miettinen, O.S.: Individual Matching with Multiple Controls in the Case of All- or-None Responses. Biometrics, 339–355, June 1969.Google Scholar
  18. 18.
    Occupational Health Studies. Occupational Health Studies Group, School of Public Health, University of North Carolina, Chapel Hill, N.C. September 1978.Google Scholar
  19. 19.
    Olin, G.R.: The Hazards of a Chemical Laboratory Environment-A Study of the Mortality in Two Cohorts of Swedish Chemists. Ind. Hyg. Assoc. J. 39: 557–562, July 1978.CrossRefGoogle Scholar
  20. 20.
    Robbins, S.L., Angell, M.: Basic Pathology, 2nd Edition. W.B. Saunders, Philadelphia, 1976.Google Scholar
  21. 21.
    Ury, H.K.: Efficiency of Case-Control Studies with Multiple Controls per Case: Continuous or Dichotomous Data. Biometrics 31: 643–649, 1975.PubMedCrossRefGoogle Scholar

Copyright information

© Online Conferences Ltd., Uxbridge, England 1979

Authors and Affiliations

  • U. Keil
    • 1
  • D. Andjelkovich
    • 1
  • E. Hunt
    • 1
  • M. Symons
    • 1
  • H. A. Tyroler
    • 1
  1. 1.Department of Epidemiology Occupational Health Studies Group School of Public HealthUniversity of North CarolinaChapel HillUSA

Personalised recommendations