The Theory of Plaque Growth Kinetics for a Lymphocyte Source

Abstract

Antibody heterogeneity is inextricably involved in the specificity and dynamics of the humoral response, and hence the latter cannot be fully understood without detailed knowledge of the former. At the same time, however, the presence of heterogeneity complicates the analysis of conventional experiments which would be used to elucidate its features. This problem might, in principle, be avoided by studies at a single cell level. That means using a method for isolating, enumerating, and identifying individual antibody secreting cells and adapting it to physical chemical studies.