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Zur Immunglobulinbildung in der menschlichen Milz

  • W. Mondorf
  • K. A. Lennert
  • M. Kollmar

Immunoglobulin Synthesis in the Human Spleen

Summary

Quantitative determinations of the three major immunoglobulins were made according to the immunodiffusion method of Mancini et al. in 23 patients following splenectomy.

A significant decrease of IgM concentration was noticed whereas concentrations of IgG and IgA proved to be unchanged.

It seems probable that the decrease in IgM concentration is due to the reduction of IgM producing cells following splenectomy.

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Literatur

  1. Begemann, H., Gehle, W.: Die Auswirkungen der posttraumatischen Splenektomie. Dtsch. med. Wschr. 84, 449–455 (1959).PubMedCrossRefGoogle Scholar
  2. Broberger, O., Gyulai, F., Hirschfeldt, J.: Splenectomy in childhood. A clinical and immunological study of 42 children splenectomized 1951–1958. Acta paediat. (Uppsala) 49, 679689 (1960).CrossRefGoogle Scholar
  3. Carvalho, I. F. DE, Borel, Y., Miescher, P. A.: Influence of splenectomy in rats on the formation of 19 S and 7S antibodies. Immunology 12, 505–515 (1967).PubMedGoogle Scholar
  4. Ellis, E. F., Smith, R. T.: The role of the spieen in immunity with special reference to the postsplenectomy problem in infants. Pediatrics 37, 111–119 (1966).PubMedGoogle Scholar
  5. Finland, M.: Serious infections in splenectomized children. Pediatrics 27, 689–691 (1961).PubMedGoogle Scholar
  6. Pribilla, W.: Über einige Funktionen der Milz. Internist (Berl.) 8, 345–357 (1967).Google Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1970

Authors and Affiliations

  • W. Mondorf
  • K. A. Lennert
  • M. Kollmar
    • 1
    • 2
  1. 1.Abteilung für Nephrologie des ZentrumsInneren MedizinDeutschland
  2. 2.Chirurgischen KlinikJohann Wolfgang Goethe-UniversitätFrankfurt/MainDeutschland

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