Zur Immunglobulinbildung in der menschlichen Milz
Immunoglobulin Synthesis in the Human Spleen
Quantitative determinations of the three major immunoglobulins were made according to the immunodiffusion method of Mancini et al. in 23 patients following splenectomy.
A significant decrease of IgM concentration was noticed whereas concentrations of IgG and IgA proved to be unchanged.
It seems probable that the decrease in IgM concentration is due to the reduction of IgM producing cells following splenectomy.
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