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The Rate of Action of Drugs on Cells

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General Pharmacology

Part of the book series: Handbuch der Experimentellen Pharmakologie ((HDBEP,volume 4))

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Abstract

The rate of response of a tissue to the action of a drug can be studied in two way:

  1. (1)

    Measurement of some graded action. The following are simple examples of this type of response: the contracture of plain or of skeletal muscle; the inhibition of the mechanical response of cardiac muscle; the relaxation of plain muscle.

  2. (2)

    Measurement of the rate of incidence of some all-or-none effect. The following are important measurements of this type: death of micro-organisms; haemolysis of red blood corpuscles; paralysis or death or small organisms.

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© 1937 Verlag von Julius Springer

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Clark, A.J. (1937). The Rate of Action of Drugs on Cells. In: General Pharmacology. Handbuch der Experimentellen Pharmakologie, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-91463-8_13

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  • DOI: https://doi.org/10.1007/978-3-642-91463-8_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-89607-1

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