The Use of Hyaluronic Acid in the Treatment of Ocular Hypotonia

  • F. Körner
Conference paper


An ocular hypotensive syndrome may result from chronically recurring uveitis and it may lead to a considerable reduction of vision. Under certain conditions the intraocular pressure may be raised for several months in these cases by intraocular injections of Healon®. These conditions, as defined after analysis of a case observed by us, are a pathological increase in outflow resistance of the trabecular system and a reduction, though not arrest, of the production of aqueous humour (Körner et al. 1985, 1986).


Hyaluronic Acid Intraocular Pressure Anterior Chamber Outflow Resistance Retinal Edema 
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  1. Denlinger JL, Balazs EA (1980) Replacement of the liquid vitreous with sodium hyaluronate in monkeys. I. Short-term evaluation. Exp Eye Res 31: 81–99PubMedCrossRefGoogle Scholar
  2. Hultsch E, Balazs EA (1975) Transport of hyaluronic acid from vitreous: mechanism and dynamics. Annual Meeting of the Association for Research and Ophthalmology (Arvo), p 2Google Scholar
  3. Körner F, Niesei P, König H (1985) Inflow and outflow relations after intraocular fluid — Healon exchange in a case of chronic ocular hypotension. Int Ophthalmol 8: 261–266CrossRefGoogle Scholar
  4. Körner F, Niesel P, König H (1986) Chronische okuläre Hypotonie: Langzeitverlauf und Therapie mit Natrium-Hyaluronat. Klin Mbl Augenheilk 188: 373–375CrossRefGoogle Scholar
  5. Laurent UBG, Fraser JRE (1983) Turnover of hyaluronate in the aqueous humor and vitreous body of the rabbit. Exp Eye Res 36: 493–504PubMedCrossRefGoogle Scholar
  6. Moses RA (1975) Intraocular pressure. In: Moses RA (ed.) Adler’s Physiology of the Eye. Clinical Application, 6th ed. Mosby, St. Louis, pp 179-209Google Scholar
  7. Schubert H, Denlinger JL, Balazs EA (1981) Na-Hyaluronate injected into the anterior chamber of the owl monkey: effect on IOP and rate of disappearance. Invest Ophthalmol Vis Sci (Suppl) 20: 118Google Scholar
  8. Widder W (1962) Tierversuche über die Verweildauer verschiedener Glaskörperimplantate. Graefe’s Arch Clin Exp Ophthalmol 164: 550–569CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • F. Körner

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