Zusammenfassung
Nach Erwähnung der Überlegungen, die dem Einsatz der immunsuppressiven Zytostatika bei Uveitis zugrunde liegen, werden die heute dafür verwendeten Medikamente und ihre Wirkungsweise vorgestellt Speziell wird dabei auf die an der Zürcher Universitätsaugenklinik gebrauchte Kombination von Zyklophosphamid und Prokarbazin hingewiesen. Es werden die absoluten und relativen Indikationen dieser Behandlung angegeben und die mit der obigen Therapie erzielten Resultate erwähnt. Schließlich werden für die 15–20% Mißerfolge solcher Behandlungen Hinweise auf andere therapeutische Möglichkeiten (Immunostimulation, Chirurgie) gegeben.
Summary
After some considerations about the necessity for an immunosuppressive therapy in severe uveitis, the currently available drugs are listed, with special reference to cyclophosphamide and procarbazine, the drug combination actually used at the University Eye Clinic in Zurich. The absolute and relative indications for these therapies are given as well as the obtained results. For the 15–20% failures, alternative treatment such as immunostimulation or surgery is proposed.
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© 1981 Springer-Verlag Berlin Heidelberg
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Martenet, AC. (1981). Immunsuppression. In: Jaeger, W. (eds) Uveitis. Deutsche Ophthalmologische Gesellschaft Bericht über die 78. Zusammenkunft in Kiel 1980, vol 78. J.F. Bergmann-Verlag, Munich. https://doi.org/10.1007/978-3-642-88589-1_42
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DOI: https://doi.org/10.1007/978-3-642-88589-1_42
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