S-Adenosyl-L-Methionine (SAMe) and Biogenic Amine Methylation Processes

  • G. Stramentinoli
  • F. Maffei
Part of the Monographien aus dem Gesamtgebiete der Psychiatrie book series (PSYCHIATRIE, volume 18)


Among catecholamines, norepinephrine (NE) and dopamine (DA) serve as synaptic mediators in the central nervous system (CNS). The dopaminergic pathways constitute the ascending nigrostriatal system and connect the dorsal neurons of the interpeduncular nucleus with the accumbens nucleus and the olfactory tubercle (20). The noradrenergic pathways, all of them ascending, originate from neurons in the pons and medulla oblongata and spread partly to the hypothalamus, preoptic area, septum, amygdala, hippocampus, and cingulate gyrus, and partly to the neocortex.


Vanillic Acid Preoptic Area Methyl Donor Methylation Process Dihydroxybenzoic Acid 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • G. Stramentinoli
    • 1
  • F. Maffei
    • 2
  1. 1.Department of BiochemistryBioResearch CompanyLiscate (Milan)Italy
  2. 2.Neuropsychiatric HospitalsVeronaItaly

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