Differentiation of the Neocortex

  • M. L. Reynolds
  • N. R. Saunders


The early evolutionary divergence of the Eutheria and Metatheria and the accessibility of the young of marsupials at a very immature stage of development make it of both theoretical and practical interest to compare the pattern of brain development in these two groups. The first aim of the study described in this chapter was to determine how the development of the neocortex in marsupials compares with more familiar eutherian species, such as the rat or sheep. The second aim was to examine the potential of these species for developmental studies, given that they are born at an extremely early stage of differentiation of many body systems, as is evident from many of the contributions to this volume.


Plexiform Layer Ventricular Zone Cortical Plate Proliferative Zone Monodelphis Domestica 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • M. L. Reynolds
  • N. R. Saunders
    • 1
  1. 1.The Wessex Area Neurosciences Group and Department of Physiology and PharmacologyUniversity of SouthamptonSouthamptonEngland

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