Mineralocorticoid action of adrenocortical hormones

  • Robert Gaunt
  • J. J. Chart
Part of the Handbuch der Experimentellen Pharmakologie book series (HEP, volume 14 / 1)


All of the physiologically active steroids of the adrenal cortex affect the metab­olism of water and electrolytes. The term “mineralocorticoids” has been used conventionally to designate those steroids such as deoxycorticosterone (DOC) and aldosterone whose known major effects at low dosage are on electrolyte and water metabolism. Such steroids, however, cannot be considered from a physiological standpoint without reference to the related actions of the “glucocorticoids,” i.e., those compounds whose major recognized actions at low doses are on some aspect of organic metabolism. Therefore, this chapter will deal with mineralocorticoid actions of the adrenal steroids in general.


Adrenal Cortex Adrenal Insufficiency Primary Aldosteronism Adrenal Function Sodium Retention 
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© Springer-Verlag Berlin Heidelberg 1962

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  • Robert Gaunt
  • J. J. Chart

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