General Discussion Remark: Energetics of Inhibitor Binding

  • D. M. Blow
Conference paper
Part of the Bayer-Symposium book series (BAYER-SYMP, volume 5)


It has always seemed to me that the central question about the trypsin inhibitor system is: Why does the inhibitor bind so strongly? I think the answer may be the key to understanding all kinds of biological receptor systems. So I asked that question during the conference and there was a fairly negative response from the audience.


Entropy Hydrolysis Ethyl Enthalpy Arginine 


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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • D. M. Blow
    • 1
  1. 1.MRC Laboratory of Molecular BiologyCambridgeGreat Britain

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