General Discussion Remark: Energetics of Inhibitor Binding
It has always seemed to me that the central question about the trypsin inhibitor system is: Why does the inhibitor bind so strongly? I think the answer may be the key to understanding all kinds of biological receptor systems. So I asked that question during the conference and there was a fairly negative response from the audience.
KeywordsEntropy Hydrolysis Ethyl Enthalpy Arginine
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