Properties of Human α1-Antitrypsin

  • J. Travis
  • D. Johnson
  • R. Pannell
Conference paper
Part of the Bayer-Symposium book series (BAYER-SYMP, volume 5)


Human blood plasma is known to contain at least six proteinase inhibitors[1]. Two of these proteins, α2-macroglobulin and α1antitrypsin, are normally present in the most significant quantities in plasma and the latter has been found to account for at least 70% of the total inhibitory activity. This protein, which should more accurately be described as an α1-proteinase inhibitor because of its broad inhibition spectrum, has been implicated in several pathological conditions primarily when low levels of the molecule are present in plasma [2].


Cellulose Sedimentation Electrophoresis Fractionation Proline 


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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • J. Travis
    • 1
  • D. Johnson
    • 1
  • R. Pannell
    • 1
  1. 1.Department of BiochemistryUniversity of GeorgiaAthensUSA

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