Properties of Human α1-Antitrypsin
Human blood plasma is known to contain at least six proteinase inhibitors. Two of these proteins, α2-macroglobulin and α1antitrypsin, are normally present in the most significant quantities in plasma and the latter has been found to account for at least 70% of the total inhibitory activity. This protein, which should more accurately be described as an α1-proteinase inhibitor because of its broad inhibition spectrum, has been implicated in several pathological conditions primarily when low levels of the molecule are present in plasma .
KeywordsCellulose Sedimentation Electrophoresis Fractionation Proline
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