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Broad Specificity Inhibitors from Sea Anemones

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Proteinase Inhibitors

Part of the book series: Bayer-Symposium ((BAYER-SYMP,volume 5))

Abstract

40 years after the discovery of a low molecular weight kallikrein inhibitor in bovine organs by Frey, Kraut, and Werle [1], Béress et al found similar inhibitors in sea anemones [2, 3]. These inhibitors show the same inhibition specifity [3, 4] as the trypsin-kallikrein inhibitor (BPTI) which occurs only in Bovinae and Caprinae. The biological function of inhibitors in sea anemones is unknown, but it is interesting that the highest concentration appears in the tentacles [5].

Supported by Sonderforschungsbereich 51, München and Deutsche Forschungsgemeinschaft (L.B.).

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References

  1. Kraut, H., Frey, E.K., Werle, E.: Z. physiol. Chem. 192, 1–21 (1930).

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  5. Kortmann, H., Fritz, H.: To be published.

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Author information

Authors and Affiliations

  1. Institut für Klinische Chemie und Klinische Biochemie, Universität München, 8000, München 2, Fed. Rep. Germany

    G. Wunderer, K. Kummer & H. Fritz

  2. Institut für Meereskunde, Universität Kiel, 2300, Kiel, Fed. Rep. Germany

    L. Béress

  3. Institut für Physiologische Chemie und Physikalische Biochemie, Universität München, 8000, München 2, Fed. Rep. Germany

    W. Machleidt

Authors
  1. G. Wunderer
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  2. K. Kummer
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  3. H. Fritz
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  4. L. Béress
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  5. W. Machleidt
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Editor information

Editors and Affiliations

  1. Institut für Klinische Chemie und Klinische Biochemie, Universität München, 8000, Munich 2, Fed. Rep. Germany

    Hanz Fritz

  2. Organisch-Chemisches Laboratorium, Technischen Universität München, 8000, Munich 2, Fed. Rep. Germany

    Harald Tschesche

  3. Department of Biology, Brookhaven National Laboratory, Upton, NY, 11973, USA

    Lewis J. Greene

  4. Biochemisches Laboratorium, Bayer AG, 5600, Wuppertal 1, Fed. Rep. Germany

    Ernst Truscheit (Editor-in-Chief) (Editor-in-Chief)

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© 1974 Springer-Verlag

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Wunderer, G., Kummer, K., Fritz, H., Béress, L., Machleidt, W. (1974). Broad Specificity Inhibitors from Sea Anemones. In: Fritz, H., Tschesche, H., Greene, L.J., Truscheit, E. (eds) Proteinase Inhibitors. Bayer-Symposium, vol 5. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87966-1_32

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  • DOI: https://doi.org/10.1007/978-3-642-87966-1_32

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-87968-5

  • Online ISBN: 978-3-642-87966-1

  • eBook Packages: Springer Book Archive

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