Skip to main content
SpringerLink
Log in

The Pathology of Megacolon

  • Conference paper
Progress in Proctology

Abstract

Four types of megacolon are recognized at present. They are:

  1. 1.

    Hirschsprung’s disease,

  2. 2.

    secondary megacolon,

  3. 3.

    acquired megacolon and

  4. 4.

    functional megacolon.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Bibliography

  1. El-Badawi, A., and E. A. Schenk: Histochemical methods for separate, consecutive and simultaneous demonstration of acetylcholinesterase and norepinephrine in cryostat sections. J. Hictochem. Cytochem. 15, 580–588 (1967).

    Article  CAS  Google Scholar 

  2. Bennett, A., J. R. Garrett, and E. R. Howard: Adrenergic myenteric nerves in Hirschsprung’s disease. Brit. med. J. 1, 487–489 (1968).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Berger, H.: Das große atonische Colon bei gewissen Obstipationsformen der Kinder und seine Behandlung mit Sympathicolytica. Ann. paediat. (Basel) 178, 187–206 (1952).

    Google Scholar 

  4. Dalla-Valle, A.: Contributo alla conoscenza della forma famigliare del megacolon congenito. Pediatria (Barcelona) 32, 569–599 (1924).

    Google Scholar 

  5. Ehrenpreis, T.: Megacolon in the newborn. A clinical and roentgenological study with special regard to the phathogenesis. Acta chir. Scand. 94, Suppl. 112 (1946).

    Google Scholar 

  6. — Acquired megacolon as a complication of recto-sigmoidectomy for Hirschsprung’s disease. Arch. Dis. Childh. 40, 180–182 (1965).

    Google Scholar 

  7. Falck, B., and C. Owman: A detailed methological description of the fluorescence method for the cellular demonstration of biogenic monoamines. Acta Univ. Lundensis, Sectio II, No 7 (1965).

    Google Scholar 

  8. Ferreira-Santos, R.: Megacolon and megarectum in Chagas’ disease. Proc. roy. Soc. Med. 54, 1047–1053 (1961).

    CAS  PubMed  Google Scholar 

  9. Gomori, G.: Histochemical demonstration of sites of choline esterase activity. Proc. Soc. exp. Biol. 68, 354–358 (1948).

    Article  CAS  PubMed  Google Scholar 

  10. Hess, R., D. G. Scarpelli, and A. G. E. Pearse: The cytochemical localization of oxidative enzymes. II. Pyridine nucleotide-linked dehydrogenases. J. biophys. biochem. Cytol. 4, 753–760 (1958).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  11. — — — Cytochemical localization of pyridine nucleotide-linked dehydrogenases. Nature (Lond.) 181, 1531–1532 (1958).

    Google Scholar 

  12. Hiatt, R. B.: The pathologic physiology of congenital megacolon. Ann. Surg. 133, 313–320 (1951).

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  13. Hukuhara, T., S. Nakayama, and T. Sumi: The role of the intrinsic mucosal reflex in the fluid transport through the denervated intestinal loop. Jap. J. Physiol. 9, 406–418 (1959).

    Article  CAS  Google Scholar 

  14. —, T. Sumi, and S. Kotani: The role of ganglion cells in the small intestine, taken in the intrinsic reflex. Jap. J. Physiol. 11, 281–288 (1961).

    Google Scholar 

  15. Kamijo, K., R. B. Hiatt, and G. B. Koelle: Congenital megacolon. A comparison of the spastic and hypertrophied segments with respect to Cholinesterase activities and sensitivities to acetylcholine, DFP and the barium ion. Gastroenterology 24, 173–185 (1953).

    CAS  PubMed  Google Scholar 

  16. Keefer, G. P., and J. F. Mokrohisky: Congenital megacolon (Hirschsprung’s disease). Radiology 63, 157–175 (1954).

    CAS  PubMed  Google Scholar 

  17. Köberle, F.: Die Chagaskrankheit. Eine Erkrankung der neurovegetativen Peripherie. Wien. klin. Wschr. 68, 333–339 (1956).

    PubMed  Google Scholar 

  18. — Die Chagaskrankheit — ihre Pathogenese und ihre Bedeutung als Volksseuche. Z. Tropenmed. Parasit. 10, 236–268 (1959).

    Google Scholar 

  19. Koelle, G. B.: Autonomie und pharmacologic control of colonic activity. Ann. N. Y. Acad. Sci. 58, 307–315 (1954).

    Article  Google Scholar 

  20. —, and J. S. Friedenwald: The histochemical method for localizing Cholinesterase activity. Proc. Soc. exp. Biol. (N. Y.) 70, 617–622 (1949).

    Google Scholar 

  21. Lenz, H.: Zur Physiologie der Peristaltik des Dünndarms. Dtsch. med. Wschr. 90, 1657–1663 (1965).

    Article  CAS  PubMed  Google Scholar 

  22. Lewitan, A., L. Nathanson, and W. R. Slade, Jr.: Megacolon and dilatation of the small bowel in Parkinsonism. Gastroenterology 17, 367–374 (1951).

    CAS  PubMed  Google Scholar 

  23. Marshak, R. H., L. J. Lester, and A. J. Friedman: Megacolon, a complication of ulcerative colitis. Gastroenterology 16, 768–772 (1950).

    CAS  PubMed  Google Scholar 

  24. Mc Inernney, G. R., W. G. Sauer, A. H. Baggenstoss, and J. R. Hodgson: Fulminating ulcerative colitis with marked colonic dilation: A clinicopathologic study. Gastroenterology 42, 244–257 (1962).

    Google Scholar 

  25. Mei, N.: Nouvelles données sur la décharge des mécanorécepteurs vagaux de l’intestin. C. R. Soc. Biol. 160, 2382–2387 (1966).

    CAS  Google Scholar 

  26. Meier-Ruge, W.: Zur Pathologie und bioptischen Diagnostik des Morbus Hirschsprung in Relation zum Megacolon acquisitum und functionale. Verh. dtsch. Ges. Path. 51, 323–328 (1967).

    CAS  Google Scholar 

  27. — Das Megacolon, seine Diagnose und Pathophysiologie. Virchows Arch. path. Anat. 344, 67–85 (1968).

    Google Scholar 

  28. —, and R. Morger: Neue Gesichtspunkte zur Pathogenese und Klinik des Morbus Hirschsprung. Schweiz. med. Wschr. 98, 209–214 (1968).

    Google Scholar 

  29. McLamed, M., and E. Kubian: Relationship of the autonomic nervous system to “functional” obstruction of the intestinal tract: report of four cases, one with perforation. Radiology 80, 22–29 (1963).

    Google Scholar 

  30. Morger, R., u. W. Meier-Ruge: Pseudo-Hirschsprung. Mschr. Kinderheilk. 114, 579 bis 581 (1966).

    CAS  PubMed  Google Scholar 

  31. Okamoto, E., and T. Ueda: Embryogenesis of intramural ganglia of the gut and its relation to Hirschsprung’s disease. J. Ped. Surg. 2, 437–443 (1967).

    Article  Google Scholar 

  32. —, T. Iwasaki, T. Kakutani, and T. Ueda: Selective destruction of the myenteric plexus: Its relation to Hirschsprung’s disease, achalasia of the esophagus and hypertrophic pyloric stenosis. J. Ped. Surg. 2, 444–455 (1967).

    Google Scholar 

  33. Scharar, L. L., and H. J. Burhenne: Megacolon associated with administration of an anticholinergic drug in a patient with ulcerative colitis. Amer. J. dig. Dis. 9, 268–274 (1946).

    Article  Google Scholar 

  34. Smith, A. N., and M. Ridgeway: Use of telemetering capsules in disorders of alimentary tract. II. Application to study of human gastrointestinal motility. Gut 3, 371–376 (1962).

    Google Scholar 

  35. Spriggs, T. L. B., J. D. Lever, P. M. Rees, and J. D. P. Graham: Controlled formaldehyde-catecholamine condensation in cryostat section to show andrenergetic nerves by fluorescence. Stain Technol. 41, 323–327 (1966).

    CAS  PubMed  Google Scholar 

  36. Zypen, E., Van Der: Licht- und elektronenmikroskopische Befunde am vegetativen Nervensystem des Colon bei Colitis ulcerosa des Menschen. Dtsch. Z. Nervenheilk. 187, 787–836 (1965).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Basel, Switzerland

    W. Meier-Ruge

Authors
  1. W. Meier-Ruge
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Chirurgische Abteilung, Stadtkrankenhauses, Wolfsburg, Germany

    J. Hoferichter (Privatdozent für Chirurgie) (Privatdozent für Chirurgie)

Rights and permissions

Reprints and permissions

Copyright information

© 1969 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Meier-Ruge, W. (1969). The Pathology of Megacolon. In: Hoferichter, J. (eds) Progress in Proctology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87959-3_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-87959-3_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-87961-6

  • Online ISBN: 978-3-642-87959-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation