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Urinary Concentration and Dilution

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Progress in Nephrology

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Abstract

Micropuncture experiments [9] and studies on isolated renal tubules [5] have demonstrated that ADII influences final urine concentration by increasing the water permeability of the epithelium of the distal convolution and collecting duct. However, it is unclear whether a possible ADH-mediated enhancement of sodium reabsorption in the loop of Henle also participates in the concentrating mechanism [4, 8]. This is worthy of serious consideration in view of the demonstration of the stimulation of sodium transport of toad bladder epithelium by ADH [6, 7].

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Author information

Authors and Affiliations

  1. Physiologisches Institut, Universität München, Deutschland

    K. Thurau

  2. Abteilung für Pharmakologie, Technischen Hochschule Aachen, West Germany

    O. Heidenreich

  3. Pathologisches Institut, Universität Würzburg, West Germany

    K. H. Langer

  4. Medizinische Universitätsklinik Tübingen, West Germany

    H. Nieth

  5. Pathologisches Institut, Universität Heidelberg, West Germany

    G. M. Eisenbach

Authors
  1. J. Schnermann
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  2. H. Valtin
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  3. H. Fischbach
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  4. W. Nagel
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Editors and Affiliations

  1. Institut de Pharmacologie, l’Université de Lausanne, 21, rue du Bugnon, CH-1005, Lausanne, Switzerland

    Georges Peters M.D. (Professor of Pharmacology. Chairman) & Françoise Roch-Ramel Ph.D. (Privatdocent) (Professor of Pharmacology. Chairman) &  (Privatdocent)

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Schnermann, J. et al. (1969). Urinary Concentration and Dilution. In: Peters, G., Roch-Ramel, F. (eds) Progress in Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87957-9_5

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  • DOI: https://doi.org/10.1007/978-3-642-87957-9_5

  • Publisher Name: Springer, Berlin, Heidelberg

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