Biochemical Aspects of Carcinogenesis with Special Reference to Alkylating Agents and Some Antibiotics
That many of the methods used in the control of cancer can themselves induce cancer, may appear as a paradox. An early example of an agent producing the two effects is radiation. Soon after their discovery, X-rays were used to treat cancer and within a decade of the discovery it was recognised that X-rays caused cancer in men exposed to the radiation. Other forms of radiation used in the control of cancer and leukaemia have been found to cause cancer. In some cases the biochemical processes involved in carcinogenesis and inhibition of growth are probably similar.
KeywordsSarcoma Cyclophosphamide Porphyrin Cytosine Guanine
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