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Wirkung von PETN auf die experimentelle Myokardischämie beim Schwein

  • T. Hohlfeld
  • Y. C. Vogel
  • M. Braun
  • K. Schrör
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Zusammenfassung

Organische Nitratester können bei akuter Myokardischämie die linksventrikuläre Kontraktionsfunktion verbessern und die Größe des infarzierten Myokardbereiches reduzieren [1–3]. Für die Prävention myokardialer Durchblutungsstörungen ist von Interesse, daß Nitrate die Thrombozytenfunktion hemmen [4]. Bemerkenswert ist auch, daß Nitrate möglicherweise die Akkumulation neutrophiler Granulozyten nach Koronarokklusion und Reperfusion herabsetzen. Entsprechende Daten wurden an Hunden, welche Glyceroltrinitrat erhielten, erhoben [5].

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Copyright information

© Steinkopff Verlag, Darmstadt 1999

Authors and Affiliations

  • T. Hohlfeld
  • Y. C. Vogel
  • M. Braun
  • K. Schrör

There are no affiliations available

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