The Far Ultraviolet Cotton Effects of Synthetic Polyamino Acids

  • B. Jirgensons
Part of the Molecular Biology Biochemistry and Biophysics book series (MOLECULAR, volume 5)


The far ultraviolet Cotton effects of synthetic polyamino acids have been studied extensively in several laboratories. Since the conformation of some of the polymers was established by other methods, attempts have been made to correlate the Cotton effect data with conformation. Poly-α-l-glutamic acid and poly-α-l-lysine are the most thoroughly investigated polymers, and they have proved their value as models for the study of protein conformation. Very important in this field are the discoveries of Blout, Schmier, and Simmons (1962), Sarkar and Doty (1966), and Greenfield, Davidson, and Fasman (1967).


Circular Dichroism Sodium Dodecyl Sulfate Solution Cotton Effect Rotatory Power Rotatory Dispersion 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1973

Authors and Affiliations

  • B. Jirgensons
    • 1
  1. 1.M. D. Anderson Hospital and Tumor Institute, Department of BiochemistryThe University of TexasHoustonUSA

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