Detection and Therapeutic Approaches to Age-Related Infertility

  • Fady I. Sharara
  • Richard T. ScottJr.
  • David B. Seifer


Two social factors, delayed childbearing and an increase in the prevalence of divorce followed by remarriage, are contributing to a growing number of women in their mid to late thirties who desire fertility at a time when fecundity is declining. One of the most difficult challenges is the evaluation and treatment of these women, who desire fertility but have diminished ovarian reserve. The latter is due to the fact that they frequently do not produce enough quality oocytes to take full advantage of the various options offered by assisted reproductive technologies. In addition, pregnancy rates during natural and assisted cycles are dramatically reduced, and the rate of spontaneous miscarriages is markedly increased.


Pregnancy Rate GnRH Agonist Ovarian Reserve Diminished Ovarian Reserve Assisted Hatching 
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Copyright information

© Springer-Verlag New York, Inc. 2002

Authors and Affiliations

  • Fady I. Sharara
  • Richard T. ScottJr.
  • David B. Seifer

There are no affiliations available

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