Abstract
Development of antitumor drugs. Modern cancer chemotherapy dates from 1946, when the first clinical reports were published by Haddow et al. on the therapeutic effect of urethane in myeloid leukemia and on nitrogen mustard in Hodgkin’s disease, chronic leukemia, and lymphoreticulosarcoma (Gilman and Philips, 1946; Goodman et al., 1946; Rhoads, 1946). Hormone treatment1 was started at about the same time (Huggins and Hodges, 1941).
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Ainbinder, N. M., V. M. Dilman, E. P. Mukhina, I. D. Nechaeva, and J. M. Sharkova: The use of the antibiotic 2703 in six cases of chorionepithelioma of the uterus. Vop. onkol. 10 (5), 103 (1964).
Allaire, F. J., E. T. Thieme, and D. R. Korst: Cancer chemotherapy with 5-fluorouracil alone and in combination with X-ray therapy. Cancer Chemother. Rep. 14, 59 (1961).
Blokhina, N. G.: The use of 5-fluorouracil in cancer patients. Vop. onkol. 10, (11), 62 (1964).
Blokhina, N. G.: The treatment of cancer of the gastrointestinal tract by 5-fluorouracil. Diss. Moscow, 1965.
Boiron, M., C. Jacquillat, M. Weil, and J. Bernard: Combination of methylglyoxal bis (guanylhydrazone) (NSC-32946) and 6-mercaptopurine in acute granulocytic leukemia. Cancer Chemother. Rep. 45, 69 (1965).
Brock, N.: Neue experimentelle Ergebnisse mit N-Lost-Phosphamidestern. Strahlentherapie 41, 347 (1959).
Bronstein, B. L., and V. G. Khodzhaev: Regional intra-arterial chemotherapy in cancer of the maxillofacial area. Vop. onkol. 10 (4), 8 (1964).
Bross, I.D. J.: Is toxicity necessary? Proc. Amer. Ass. Cancer Res. 6, 8 (1965).
Brulé, G., J. R. Schlumberger, and C. Griscelli: N-isopropyl-α-2(-methyl-hydrazmo)-p-toluamide hydrochloride in treatment of solid tumors. Cancer Chemother. Rep. 44, 31 (1965).
Burchenal, J. H.: Recent advances and perspectives in the chemotherapy of acute leukemia. Fifth National Cancer Conference: Philadelphia, 1964 a.
Burchenal, J. H.: Improvement of cancer chemotherapy in man. Multiple drug therapy. Acta Un. int. Cancr. 20, 48 (1964 b).
Chebotareva, L. I.: Long-term results in treatment of testicular seminoma with sarcolysin. In 8th International Cancer Congress: Moscow, Medgiz, 346 (1962)
Chebotareva, L. I.: Long-term results in treatment of testicular seminoma with sarcolysin. Acta Un. Int. Cancr. 20, 380 (1964).
Creech, O. jr., E. T. Krementz, R. F. Ryan, and J.N. Winblad: Chemotherapy of cancer: regional perfusion utilizing an extracorporeal circuit. Ann. Surg. 148, 616 (1958).
Davis, W., and L. F. Larionov: Progress in chemotherapy of cancer. Bull. Wld Hlth Org. 30, 327 (1964).
Dederick, M. M.: Effect of actinomycin D and 5-fluorouracil in combination with X-ray in carcinoma of the lung. Proc. Amer. Ass. Cancer Res. 5, 14 (1964).
Denk, W., K. Karrer, and P. Wurnig: Ueber den Wert und die Risiken einer postoperativen Chemotherapie maligner Tumoren. Arzneimittel-Forsch. 11 (2a), 233 (1961).
Druckrey, H.: Pharmacological tests in cancer chemotherapy. Acta Un. int. Cancr. 15 bis, 85 (1959).
Druckrey, B. T. Kuk, D. Schmahl, and D. Steinhoff: Kombination von Operation und Chemotherapie beim Krebs. Münch. med. Wschr. 100, 1913 (1958).
Emmanuel, N. M., L. M. Dronova, I. P. Konovalova, Z. K. Maizus, and I. P. Skibida: Antileukemic action of 2,6-di (tert.) butyl-4-methylchinol (Ionol Dokl). Akad. Nauk SSSR. Otd. Biokh. 152, 481 (1963).
Emmanuel, and L. P. Lipchina: Anti-tumor activity and the mechanism of action of radical reaction inhibitors. In 8th International Cancer Congress: Moscow, Medgiz, (1962)
Emmanuel, and L. P. Lipchina: Anti-tumor activity and the mechanism of action of radical reaction inhibitors. Acta Un. int. Cancr. 20 (1–2), 103 (1964).
Farber, S.: Current clinical and experimental studies in cancer chemotherapy. Cancer Chemother. Rep. 13, 154 (1961).
Farber, L. K. Diamond, R. D. Marker, R. F. Sylvester, and J. A. Wolff: Temporary remission in the acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid (aminopterin). New Engl. J. Med. 238, 787 (1948).
Foye, L. V. jr., F. M. Willett, B. Hall, and M. Roth: The potentation of radiation effect with 5-fluorouracil. Cancer Chemother. Rep. 6, 12 (1960).
Frank, W., and A. R. Osterberg: Mitomicin C — an evaluation of the Japanese reports. Cancer Chemother. Rep. 9, 144 (1960).
Freckman, H. A.: Cancer chemotherapy: continuous intraarterial infusion. Cancer Chemother. Rep. 28, 57 (1963).
Freireich, E. J., M. Karon, and E. Frei: Quadruple combination therapy (VAMP) for acute lymphocytic leukemia of childhood. Proc. Amer. Ass. Cancer Res. 5, 20 (1964).
Gilman, A., and F. S. Philips: The biological actions and therapeutic applications of the β-chloroethyl-amines and sulfides. Science, 103, 2675, 409 (1946).
Goldin, A., and N. Mantel: The employment of combinations of drugs in the chemotherapy of neoplasia. Cancer. Res. 17, 635 (1952).
Golomb, F. M., B. P. Sammons, and J. C. Wright: A new technique of visceral artery catheterization for infusion cancer chemotherapy. Proc. Amer. Ass. Cancer Res. 5, 22 (1964).
Goodman, L. S., M. L. Wintrobe, N. Dameshek, M. I. Goodman, A., Gilman, and M. T. McLennan: Nitrogen mustard therapy. Use of methyl-bis-(β-chloroethyl)-amine hydrochloride and tris-(β-chloroethyl)-amine hydrochloride for Hodgkin’s disease, lymphosarcoma, leukemia and certain allied and miscellaneous diseases. Amer. Med. Ass. 132, 126 (1946).
Greenspan, E. M.: Combinations of methotrexate, thio-tepa and 5-fluorouracil in advanced breast carcinoma. Proc. Amer. Ass. Cancer Res. 5, 23 (1964).
Hananian, J., J. F. Holland, and P. Sheche: Intensive chemotherapy of acute lymphocytic leukemia in children. Proc. Amer. Ass. Cancer Res. 6, 26 (1965).
Harris, M. N., T. Medrek, F. M. Golomb, S. L. Gumport, A. H. Postel, and J. C. Wright: Chemotherapy with streptonigrin in advanced cancer. Proc. Amer. Ass. Cancer Res. 5, 25 (1964).
Hertz, R., D. M. Bergenstal, M. B. Lipsett, E. B. Price, and T. F. Hillebish: Chemotherapy of choriocarcinoma and related trophoblastic tumors in women. J. Amer. med. Ass. 168, 845 (1958).
Hertz, J. L. Lewis jr., and M. B. Lipsett: Five years experience with chemotherapy of metastatic choriocarcinoma and related trophoblastic disease in women. Proc. Amer. Ass. Cancer Res. 3, 235 (1961).
Hertz, and M. C. Li: Cited by Cancer Chemotherapy Abstr. 5, 73 (1964).
Hertz, M. B. Lipsett, and R. H. Moy: Effect of vincaleukoblastine on metastatic choriocarcinoma. Cancer Res. 20, 1050 (1960).
Hesse, F., and G. Kampen: Orale Dauermedikation von Bayer E-39. Krebsarzt 12, 150 (1957).
Huggins, C., and C.V. Hodges: The effect of castration, of oestrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1, 293 (1941).
Hurley, J. D.: Perfusion therapy with streptonigrin. Proc. Amer. Ass. Cancer Res. 5, 29 (1964).
Ivanova, Ye. M.: Direct and long-term results of treatment of Hodgkin’s disease with Dopan. In 8th International Cancer Congress: Moscow, Medgiz, 345 (1962)
Ivanova, Ye. M.: Direct and long-term results of treatment of Hodgkin’s disease with Dopan. Acta Un. Int. Cancr. 20, 375 (1964).
Johnson, R. O., W. A. Kisken, and A. R. Curreri: The response of squamous cell carcinoma to intra-arterial infusion with 5-fluorouracil. Cancer Chemother. Rep. 24, 29 (1962).
Jones, A.C.: Thio-tepa in the treatment of tumours of the bladder. Lancet, 2, 615 (1961).
Karon, M., S. Freireich, and P. Carbone: Effective combination therapy of adult leukemia. Proc. Amer. Ass. Cancer Res. 6, 34 (1966).
Karrer, K.: Zur kombinierten cytostatischen und operativen Behandlung des Carcinoms. Arzneimittel-Forsch. 14, 859 (1964).
Kazansky, D. A.: Regional chemotherapy of maxillary, lingual and pharyngeal tumors by the method of carotid perfusion and infusion. Vop. onkol. 11, 42 (1965).
Kisken, W. A., R. O. Johnson, and A. R. Curreri: A technique of intra-arterial infusion. Cancer chemotherapy Rep. 24, 27 (1962).
Krementz, E. T., and O. Creech Jr.: Current evaluation of cancer chemotherapy by perfusion. Proc. Amer. Ass. Cancer Res. 5, 37 (1964).
Larionov, L. F.: Immediate and remote results of chloroethylamine treatment of Hodgkin’s disease. Brit. med. J. 1, 252 (1956).
Larionov, L. F.: Cancer chemotherapy, Moscow: Medgiz 1962 (English edition. London: Pergamon Press 1965).
Larionov, L. F.: Ten years of experimental and clinical study and use of sarcolysin. Moscow: Medexport 1965.
Larionov, L. F., and M. A. Chudakova: The treatment of esophageal carcinoma by sarcolysin with colchamine. Vop. onkol. 9 (12), 3 (1963).
Larionov, L. F., and M. A. Ziv: Late results of chemotherapy of Hodgkin’s disease. Vop. onkol. 4 (2), 161 (1958).
Li, M. Ch.: Management of choriocarcinoma and related tumors of uterus and testis. Med. Clin. N. Amer. 45, 661 (1961).
Merkulova, N. V.: Treatment of multiple myeloma with sarcolysin. In 8th International Cancer Congress, Moscow: Medgiz, 347 (1962)
Merkulova, N. V.: Treatment of multiple myeloma with sarcolysin. Acta Un. int. Cancr. 20, 389 (1964).
Merkulova, N. V.: Treatment of multiple myeloma with sarcolysin. Vop. onkol. 10 (3), 51 (1964).
Mitchell, J. S.: Clinical trials of tetrasodium 2-methyl-1:4-naphthohydroquinone diphosphate as a radiosensitiser. A. R. Brit. Emp. Cancer Campgn 34, 274 (1954).
Molkov, Yu. N.: Prevention by aurantin of recurrence and metastases after surgical removal of transplantable tumors. Vop. onkol. 6 (9), 19 (1960).
Movsesyan, A. Kh. Cited by Vermel, E. M.: The next tasks of cancer chemotherapy. Vop. onkol. 11 (6), 115 (1965).
Owens, G., R. Javid, and L. Belmusto: Intraarterial vincristine therapy of primary gliomas. Proc. Amer. Ass. Cancer Res. 5, 49 (1964).
Paterson, E., A. Haddow, J. A. Thomas, and J. M. Watkinson: Leukaemia treated with urethane combined with deep X-ray therapy. Lancet, 1, 677 (1946).
Perevodchikova, N. I.: The use of chloroethylamines in the oncological clinic. Inaugur. Diss.: Moscow (1965).
Rhoads, C. P.: Nitrogen mustard in the treatment of neoplastic diseases. J. Amer. med. Ass. 131, 656 (1946).
Sorokina, I. B.: The study of combined action of 6-mercaptopurine with some other drugs of chloroethylamino group on transplantable mouse tumors. Vop. Onkol. 3 (6), 683 (1957).
Stehlin, J. S. jr., R. L. Clark, E. C. White, and J. L. Smith: Adjuvant regional chemotherapy (perfusion) for malignant melanoma. Amer. Surg. 25, 595 (1959).
Sullivan, R. D., E. Miller, and M. P. Sykes: Antimetabolite-metabolite combination cancer chemotherapy: effects of intra-arterial methotrexate-intramuscular citrovorum factor therapy in human cancer. Cancer, 12, 1248 (1959).
Sullivan, C. W. Yung, E. Miller, N. Gladstein, B. Clarkson, and J. H. Burchenal: The clinical effect of the continuous administration of fluorinated pyrimidines. Cancer Chemother. Rep. 8, 77 (1960).
Sullivan, E. Miller, W. Z. Zurek, and F. R. Rodrigues: Clinical effects of prolonged infusion of streptonigrin (NSC-45383) in advanced cancer. Cancer Chemother. Rep. 33, 27 (1963).
Sullivan, E. Watkinson Jr., W. S. Zurek, and A. M. Kazei: Chemotherapy of liver cancer by prolonged ambulatory hepatic artery infusion. Proc. Amer. Ass. Cancer Res. 6, 63 (1965).
Trapeznikov, N. N., and I. A. Avdeeva: Preliminary data in regional chemotherapy of malignant tumors of the extremities by perfusion. In 8th International Cancer Congress, Moscow: Medgiz, 350 (1962)
Trapeznikov, N. N., and I. A. Avdeeva: Preliminary data in regional chemotherapy of malignant tumors of the extremities by perfusion. Acta Un. Int. Cancr. 20, 462 (1964).
Watkins, E. jr.: Chronometric infusor — an apparatus for protracted ambulatory infusion therapy. New Engl. J. Med. 269, 850 (1963).
Wright, J. C., F. M. Golomb, and S. Gumport: Summary of results with methylene thiophosphoramide. Ann. N. Y. Acad. Sci. 68, 937 (1958).
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Larionov, L.F. (1967). Cancer Chemotherapy. In: Manuila, L., Moles, S., Rentchnick, P. (eds) New Trends in the Treatment of Cancer. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87620-2_3
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DOI: https://doi.org/10.1007/978-3-642-87620-2_3
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