Advertisement

Acute Dyskalemic Periodic Paralysis

  • Uta Meyding-Lamadé
  • Robert Stingele
  • Michael N. Diringer
  • Daniel F. Hanley

Abstract

The periodic paralyses are rare disorders of skeletal muscle characterized by transient, often acute attacks of muscle weakness. The associated alterations of serum potassium concentration have led to a classification into hypo-, hyper-, and normokalemic forms (Table 1). These occur as primary disorders, mostly transmitted as an autosomal dominant trait with variable expressivity, which have to be distinguished from secondary or acquired periodic paralysis, e.g., associated with thyrotoxicosis. Electrolyte changes are less marked in primary periodic paralysis than in secondary periodic paralysis.

Keywords

Periodic Paralysis Autosomal Dominant Trait Ancillary Test Periodic Para Hypokalemic Periodic Paralysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Suggested Reading

  1. Barchi RL, Furman RE (1992) Pathophysiology of myotonia and periodic paralysis. In: Ashbury AK, McKhann GM, McDonald WI (eds) Diseases of the nervous system, clinical neurobiology, vol 1. ButterworthsHeinemann, Sevenoaks, pp 146 – 163Google Scholar
  2. Buruma OJS, Schipperheyn JJ (1979) Periodic paralysis. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 41. Elsevier, New York, pp 147 – 174Google Scholar
  3. Dalakas MC, Engel WK (1983) Treatment of permanent muscle weakness in familial hypokalemic periodic paralysis. Muscle Nerve 6: 182 – 186PubMedCrossRefGoogle Scholar
  4. Griggs RC, Resnick J, Engel WK (1983) Intravenous treatment of hypokalemic periodic paralysis. Arch Neurol 40: 539 – 540PubMedCrossRefGoogle Scholar
  5. Jerusalem F, Zierz S (1992) Episodische Lähmungen. In: Jerusalem F, Zierz S (eds) Muskelerkrankungen — Klinik — Therapie — Pathologie. Thieme, Stuttgart, pp 311 – 316Google Scholar
  6. Riggs JE, Griggs RC (1979) Diagnosis and treatment of the periodic paralyses. Clin Neuropharmacol 4: 123 – 138CrossRefGoogle Scholar
  7. Riggs JE, Griggs R, Moxley RT (1984) Dissociation of glucose and potassium arterial-venous differences across the forearm by acetazolamide. Arch Neurol 41: 35 – 38PubMedCrossRefGoogle Scholar
  8. Ricker K, Rohkamm R, Böhlen R (1986) Adynamia episodica and paralysis periodica paramyotonica. Neruology 36: 682 – 686CrossRefGoogle Scholar
  9. Rüdel R, Lehmann-Horn F, Ricker K, Küther G (1984) Hypokalemic periodic paralysis: in vitro investigation of muscle fibre parameters. Muscle Nerve 7: 110 – 120PubMedCrossRefGoogle Scholar
  10. Torres CF, Griggs R, Moxley RT, Bender AN (1981) Hypokalemic periodic paramyotonica. Neurology 31: 1423 – 1428PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • Uta Meyding-Lamadé
  • Robert Stingele
  • Michael N. Diringer
  • Daniel F. Hanley

There are no affiliations available

Personalised recommendations