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Septic Embolic Encephalitis

  • Derk Krieger
  • Johannes Brachmann
  • Werner Hacke

Abstract

Septic embolic encephalitis (SEE) results from infectious, ischemic, and hemorrhagic damage to the neuro-parenchyma following infective thromboembolism from any part of the body. The heart is the most common source (infective endocarditis), followed by bacteremia and pulmonary infections. At autopsy, SEE is characterized by diffuse congestion and hyperemia of the leptomeninges, cerebral edema, and sometimes focal subarachnoid hemorrhage. Numerous microabscesses can be seen and occasionally they coalesce to form space-occupying macroabscesses. Vessel occlusion by thromboemboli and bacterial vasculopathy (including septic erosion of the vessel wall) can result in cerebral ischemia, intracerebral hemorrhage, or both. Evaluation and treatment of septic embolic encephalitis in the neurocritical care unit requires an interdisciplinary approach.

Keywords

Infective Endocarditis Cerebral Malaria Prosthetic Valve Brain Abscess Serratia Marcescens 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Suggested Reading

  1. Aronow WS (1991) Etiology and pathogenesis of thromboembolism. Herz 16: 395–404 (no 6)Google Scholar
  2. Dajani AS, Bisno AL, Chung KJ, Durack DT, Freed M, Gerber MA, Karchmer AW, Millard HD, Rahimtoola S, Shulman ST, Watanakunakorn C, Taubert KA (1992) Prevention of bacterial endocarditis. Heart Dis Stroke 1: 53–57Google Scholar
  3. Davenport J, Hart RG (1990) Prosthetic valve endocarditis 1976–1987. Antibiotics, anticoagulation and stroke. Stroke 21: 993–999Google Scholar
  4. David G, Sherman MD (1990) Cardiac embolism: the neurologist’s perpective. Am J Cardiol 65: 32C - 37CCrossRefGoogle Scholar
  5. Paschalis C, Pugsley W, John R, Harrison MJ (1990) Rate of cerebral embolic events in relation to antibiotic and anticoagulant therapy in patients with bacterial endocarditis. Eur Neurol 30 (2): 87–90PubMedCrossRefGoogle Scholar
  6. Salgado AV, Furlan AJ, Keys TF, Nichols TR, Beck GJ (1989) Neurologic complications of endocarditis. A 12-year experience. Neurology 39: 173–178PubMedCrossRefGoogle Scholar
  7. Tettenborn B, Krämer G, Erbel R (1991) Prophylaxis and acute therapy of arterial embolism with special reference to cerebral embolism. Herz 16: 444–455 (no 6)Google Scholar
  8. Ting W, Silverman N, Levitsky S (1991) Valve replacement in patients with endocarditis and cerebral septic emboli. Ann Thorac Surg 51(1):18–21 (discussion 22 )Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • Derk Krieger
  • Johannes Brachmann
  • Werner Hacke

There are no affiliations available

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