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Multiple Primary Malignant Neoplasms of Different Tissues or Organs

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Multiple Primary Malignant Neoplasms

Abstract

When the inquiring physician encounters a patient with multiple malignant neoplasms of two or more different tissues of origin he will frequently succumb to the urge of speculation. He must wonder if serendipity has offered him in this patient the key to common etiologic influences inciting the two neoplasms, or perhaps to common factors of predisposition shared by the organs or tissues giving rise to these neoplasms. If the patient has received some form of therapy for an initial neoplasm, the physician may well question the possible role the therapeutic procedure might have had in inducing the subsequent neoplasm. Perhaps patients with two distinct types of cancer may show more distinct hereditary patterns than have been demonstrable to date in patients with single cancers. When one is studying a group of patients with multiple primary cancers, the urge to such speculation becomes almost irresistible.

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Moertel, C.G. (1966). Multiple Primary Malignant Neoplasms of Different Tissues or Organs. In: Moertel, C.G. (eds) Multiple Primary Malignant Neoplasms. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87565-6_2

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