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NMR spectroscopy From experimental to clinical spectroscopy

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MRI of the Body

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Abstract

Soon after its discovery, the nuclear magnetic resonance (NMR) phenomenon became one of the most important tools of chemical analysis, which allowed the in vitro analysis of substances without splitting the molecules. In NMR, the excitation of a chemical element by a radiofrequency wave is sufficient to obtain a signal providing a great deal of information about the structure of the molecule this element belongs to. It is then theoretically possible to study biologically interesting molecules in animals or even in man, thus allowing chemical analysis leading to the direct observation of cell metabolism. In medical practice, this technique was not feasible until magnets with an intense field strength were built with an inside diameter large enough for the human body. The fast development of magnetic resonance imaging (MRI) raised early hopes that the same system would provide both images of an organ and chemical analysis of one localized area of these images.

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Authors
  1. J. Bittoun
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  2. A. Leroy-Willig
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Editors and Affiliations

  1. Service de Radiodiagnostic, Institut Gustave Roussy, rue Camille Desmoulins, 94805, Villejuif Cedex, France

    Daniel Vanel M.D.

  2. Service of Magnetic Resonance Imaging, Centre Hospitalier Princesse Grace, 98000, Principality of Monaco

    Michael T. Mc Namara M.D. (Chief) (Chief)

  3. Service de Médecine Nucléaire, Institut Gustave Roussy, rue Camille Desmoulins, 94805, Villejuif Cedex, France

    O. Arcangioli M.D.

  4. Service de Radiologie, Hôtel Dieu, 2, place du Parvis de Notre Dame, 75004, Paris, France

    L. Arrive M.D. , J.-N. Buy M.D. , J. Ecoiffier Prof. , P. Grenier Prof. , L. Malbec M.D. , E. Meary M.D.  & D. Vadrot Prof. , , , , ,  & 

  5. Service de Radiophysique, Institut Gustave Roussy, Rue Camille Desmoulins, 94805, Villejuif Cedex, France

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  6. Service de Radiologie, Hôpital Bichat, 46, rue Henri Huchard, 75018, Paris, France

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  8. Service de Biophysique et Médecine Nucléaire, CHU de Bicêtre, 94275, Le Kremlin Bicêtre Cedex, France

    J. Bittoun M.D.  & I. Idy-Peretti M.D.  & 

  9. Service de Radiologie, Hôpital de Montmorency, 95160, Montmorency, France

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  27. Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA

    H. Kressel Prof.

  28. Médecine Nucléaire, Institut Gustave Roussy, rue Camille Desmoulins, 94805, Villejuif Cedex, France

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© 1989 Springer-Verlag France

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Bittoun, J., Leroy-Willig, A. (1989). NMR spectroscopy From experimental to clinical spectroscopy. In: Vanel, D., et al. MRI of the Body. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87556-4_4

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  • DOI: https://doi.org/10.1007/978-3-642-87556-4_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-87558-8

  • Online ISBN: 978-3-642-87556-4

  • eBook Packages: Springer Book Archive

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