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Genetic Aspects of Lipidoses

  • Chapter
Lipids and Lipidoses

Abstract

The lipidoses, as covered by this book,are inborn errors of metabolism, although some of them may be rather strongly subjected to modification by exogenous influences. Their exact classification depends largely on clinical, morphological, and particularly biochemical criteria. A few years ago only, our knowledge of the biochemistry of this group of disesaes was so insufficient, that e.g. in 1959 Harris in his well known work on Human Biochemical Genetics did not include a discussion of disturbances of lipid metabolism. Even to-day, we must admit, our understanding of the basic processes involved is incomplete to the extent that in many of the diseases, which customarily are included among the hereditary dis­orders of lipid metabolism, because the most obvious abnormalities are to be found in the area of blood lipids or in lipid storage of the tissues, it is not even proved, whether the primary defect is not located in carbohydrate or protein metabolism rather than in lipid metabolism.

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  1. W. Fuhrmann
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Fuhrmann, W. (1967). Genetic Aspects of Lipidoses. In: Schettler, G. (eds) Lipids and Lipidoses. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87367-6_18

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  • DOI: https://doi.org/10.1007/978-3-642-87367-6_18

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