Procion Yellow and Cobalt as Tools for the Study of Structure-Function Relationships in Vertebrate Central Nervous Systems

  • Rodolfo Llinás


The relationship between neuronal morphology and neuronal function may be approached from two different points of view. It has been stated in the past that neurons which have similar inputs and whose axons terminate on similar target cells have similar functions (“l’identité ou la dissemblance physiologique des neurones se jugera exclusivement par la similitude ou la difference de leurs relations”—Ramón y Cajal, 1909, p. 149). This statement summarizes the view held by many circuit analysts in neurobiology today, namely that the shape of neurons has little to do with their integrative properties. In a holistic sense, therefore, this approach postulates that connectivity is the dominant morphological parameter determining the functional properties of the nervous system.


Purkinje Cell Cerebellar Purkinje Cell Synaptic Potential Intracellular Injection Renshaw Cell 
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  • Rodolfo Llinás

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