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Syphilis

  • Ambrose J. King
Part of the Encyclopedia of Urology book series (HDBUROL, volume 9 / 2)

Abstract

The discovery that penicillin was a safe and effective remedy for the treatment of syphilis coincided with a period of extremely high prevalence of the infectious manifestations of the disease during World War II, and was followed by a spectacular fall in incidence after the peak year of 1946. This fact has led to a spirit of optimism among public health administrators and others, who believe that the problem is solved and eradication of the disease is only a matter of time. In Western Europe and in North America, where measures of control are wellorganised and reliable figures of incidence are available, there is some evidence to support this view. In Norway, for instance, (Gjessing, 1956) the incidence of syphilis fell from 6.6 per 10,000 of the population in 1943 to 0.6 per 10,000 in 1955. In France (Durel, 1956) the official figures for the incidence of early syphilis were 12,094 in 1945 and 1,156 in 1955. These do not include many cases seen by general practitioners which are never reported. In Sweden (Tottie, 1956), during the three years preceding 1956, known cases of syphilis had been limited to 150 to 170 a year. Cn Canada (Lossing and Allen, 1956) the incidence of syphilis of all types declined from 137.8 per 100,000 in 1944 to 15.5 per 100,000 in 1955. The decline in infectious syphilis has been even more spectacular, for in 1945 early syphilis represented 37 per cent of all reported syphilis, while by 1955 this proportion had diminished to 7 per cent. Only 128 cases of primary and 49 of secondary syphilis were reported for the whole of Canada in 1955. In Australia (Booth, 1956) the figures for the State of New South Wales indicate the general trend.

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References

A. Epidemiology

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III. The treponemal immobilisation test (TPI test)

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IV. Other verification tests 1. The Neurath test

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2. The Kahn verification test

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3. Treponemal complement fixation test

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4. Treponemal agglutination test

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5. Treponemal immune-adherence test

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V. Non-syphilitic reactions

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E. The treatment of syphilis I. General medical care

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II. The treatment of early syphilis 1. Intensive arsenotherapy

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2. Fever therapy

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3. Penicillin

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4 The combination of penicillin and arsenic 5 The combination of penicillin and bismuth

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8. The composition of penicillin

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9. Further assessment

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11. Repository preparations

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13. Streptomycin

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14 Chloramphenicol (Chloromycetin)

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15 Chlortetracycline (Aureomycin)

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16. Oxytetracycline (Terramycin)

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17. Carbomycin (Magnamycin)

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III. Treatment of late syphilis

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F. The prognosis of syphilis I. Untreated syphilis

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II. Syphilis and marriage

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III. Transmission to the foetus

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IV. The results of modern treatment

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Copyright information

© Springer-Verlag Berlin Heidelberg 1959

Authors and Affiliations

  • Ambrose J. King

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