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Prothesen-Endokarditis

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Infektiöse Endokarditis

Zusammenfassung

Die kontinuierliche Fortentwicklung der Konstruktion, der Materialien und der Fertigung von Herzklappenprothesen sowie ihre Implantation vor dem Eintritt irreversibler Komplikationen hat nachhaltig zur Verbesserung der Prognose und Lebensqualität von Patienten mit funktionseingeschränkten nativen Herzklappen beigetragen (15, 61, 95). Diese augenfällig günstige Beeinflussung des natürlichen Verlaufs erworbener Herzklappenfehler wird durch eine kleine Zahl schwerwiegender Komplikationen erkauft, die im Einzelfall die weitere Prognose erheblich beeinträchtigen können. Bei den lebensbedrohlichen Komplikationen steht die Prothesen-Endokarditis zahlenmäßig an erster Stelle (15, 59, 65, 86). Das Implantat prädisponiert seinen Träger in besonderer Weise für Polymer-assoziierte Infektionen, insbesondere Novobiocin-empfindliche, Koagulase-negative Staphylokokken (S.-epidermidis-Gruppe; 93) mit zum Teil phänotypischen Variationen, die eine mögliche Ursache dafür sein mögen, daß diese Erreger über besondere Fähigkeiten verfügen, unter unterschiedhchen Bedingungen verschiedenartigste Oberflächen zu besiedeln (116, 130).

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  1. Dieter Horstkotte
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    Klaus Gahl

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© 1994 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt

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Horstkotte, D. (1994). Prothesen-Endokarditis. In: Gahl, K. (eds) Infektiöse Endokarditis. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-87079-8_9

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  • DOI: https://doi.org/10.1007/978-3-642-87079-8_9

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