Steroid Hormones and Ageing

  • R. I. Dorfman
Part of the Symposion der Deutschen Gesellschaft für Endokrinologie book series (ENDOKRINOLOGIE, volume 5)


Advanced technics of steroid hormone analysis in body fluids coupled with a more detailed knowledge of steroid hormone metabolism permits at this time the formulation of a working hypothesis to explain the changes in steroid hormones in the ageing individual. In this review a brief summary of our present knowledge of steroid biosynthesis will be presented together with an analysis of the changes that are associated with the ageing process.


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  1. Baggett, B., L. L. Engel, K. Savard and R. I. Dorfman: J. biol. Chem. 221, 931 (1956).PubMedGoogle Scholar
  2. Bloch, E., K. Benirschke and R. I. Dorfman: J. clin. Endocr. 15, 379 (1955).CrossRefGoogle Scholar
  3. Bloch, E., K. Benirschke and E. Rosemberg: Endocrinology 58, 598 (1956).PubMedCrossRefGoogle Scholar
  4. Dorfman, R. I.: Amer. J. Med. 21, 679 (1956).PubMedCrossRefGoogle Scholar
  5. Dorfman, R. I.: Ann. Rev. Biochem. 26, 529 (1957).CrossRefGoogle Scholar
  6. Dorfman, R. I. and R. A. Shipley: Androgens, Biochemistry, Physiology and Clinical Significance. New York: John Wiley & Sons, Inc. 1956.Google Scholar
  7. Hamburger, C.: Acta endocr. (Kbh.) 1, 19 (1948).Google Scholar
  8. Hamilton, H. B., and J. B. Hamilton: J. clin. Endocr. 8. 433 (1948).PubMedCrossRefGoogle Scholar
  9. Heard, R. D. H., E. G. Bligh, M. C. Cann, P. H. Jellinck, V. J. O’donnell, B. G. Rao and J. L. Webb: Recent Progr. Hormone Res. 12, 45 (1956).PubMedGoogle Scholar
  10. Heard, R. D. H., P. H. Jelinck and V. J. O’Donnell: Endocrinology 57, 200 (1955).PubMedCrossRefGoogle Scholar
  11. Heller, A. K., and R. A. Shipley: J. clin. Endocr. 11, 945 (1951).PubMedCrossRefGoogle Scholar
  12. Meyer, A. S.: Biochem. biophys. Acta 24, 1435 (1955).Google Scholar
  13. Pincus, G., R. I. Dorfman, L. P. Romanoff, B. L. Rubin, E. Bloch, J. Carlo and H. Freeman: Recent Progr. Hormone Res. 11, 307 (1955).Google Scholar
  14. Pincus, G., R. I. Dorfman, L. P. L. P. Romanoff and J. Carlo: J. Geront. 9, 113 (1954).PubMedGoogle Scholar
  15. Rubin, B. L., R. I. Dorfman and G. Pincus: Ciba Found. Coll. 1, 126 (1955).Google Scholar
  16. Savard, K., R. I. Dorfman, B. Baggett and L. L. Engel: J. clin. Endocr. 16, 1629 (1956).PubMedCrossRefGoogle Scholar
  17. Savard, K., J. L. Gabrilove and L. J. Soffer: Proc. Endocrine Society, 39th Meeting, New York City, p. 89, 1957.Google Scholar
  18. Slaunwhite, W. R. jr., and L. T. Samuels: J. biol. Chem. 220, 341 (1956).PubMedGoogle Scholar
  19. Solomon, S., P. Levitan and S. Lieberman: Rev. canad. Biol. 15, 282 (1956).Google Scholar
  20. Stone, D., and O. Hechter: Arch. Biochem. 51, 457 (1954).PubMedCrossRefGoogle Scholar

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© Springer-Verlag oHG. Berlin · Göttingen · Heidelberg 1958

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  • R. I. Dorfman

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