Abstract
The American College of Chest Physicians/Society of Critical Care Medicine developed a set of terms and definitions to define sepsis in a more precise manner. The term systemic inflammatory response syndrome (SIRS) was coined to describe the systemic response to a wide variety of insults and characterized by two or more of the following clinical manifestations:
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1.
A body temperature of >38°C or <36°C
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2.
A heart rate of >90 beats/min
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3.
Tachypnea, as manifested by a respiratory rate of >20 breaths/min
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4.
A WBC count of >12,000 cells/mm3, or <4000 cells/mm3 or the presence of >10% immature neutrophils
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Selected References
Bone RC. The sepsis syndrome: definition and general approach to management. Clin Chest Med. 1996;17:175–182.
Bollaert PE, Bauer P, Audibert G, Lambert H, Larcan A. Effects of epinephrine on hemodynamics and oxygen metabolism in dopamine-resistant septic shock. Chest. 1990;98:949–953.
Briegel J, Forst H, Haller M, et al. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single- center study. Crit Care Med. 1999;27:723–732.
Gattinoni L, Brazzi L, Pelosi P, et al. A trial of goal-oriented hemodynamic therapy in critically ill patients. N Engl J Med. 1995;333:1025–1032.
Hayes MA, Timmins AC, Yau E, et al. Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med. 1994;330: 1717–1722.
Marik PE, Varon J. The hemodynamic derangements in sepsis: implications for treatment strategies.Chest. 1998;114:854–860.
Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee TS. Prospective trial of supranormal values of survivors as therapeutic goals in high risk surgical patients. Chest. 1988;94:1176–1186.
Society of Critical Care Medicine Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20: 864–874.
Third European Consensus Conference in Intensive Care Medicine. Tissue hypoxia: how to detect, how to correct, how to prevent? Am J Respir Crit Care Med. 1996;154:1573–1578.
Van den Berghe G, de Zegher F. Anterior pituitary function during critical illness and dopamine treatment. Crit Care Med. 1996;24:1580–1590.
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© 2001 Springer-Verlag New York, Inc.
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Marik, P.E. (2001). Management of Septic Patients. In: Handbook of Evidence-Based Critical Care. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-86943-3_42
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DOI: https://doi.org/10.1007/978-3-642-86943-3_42
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